메뉴 건너뛰기




Volumn 163, Issue , 2014, Pages 47-55

Serotonin 2A receptor clustering in peripheral lymphocytes is altered in major depression and may be a biomarker of therapeutic efficacy

Author keywords

5 HT2A receptor; Membrane protein clustering; Mood disorders; Peripheral biomarkers; Translational psychiatry

Indexed keywords

5-HT2A RECEPTOR; MEMBRANE PROTEIN CLUSTERING; MOOD DISORDERS; PERIPHERAL BIOMARKERS; TRANSLATIONAL PSYCHIATRY;

EID: 84899069087     PISSN: 01650327     EISSN: 15732517     Source Type: Journal    
DOI: 10.1016/j.jad.2014.03.011     Document Type: Article
Times cited : (28)

References (34)
  • 1
    • 79953697662 scopus 로고    scopus 로고
    • 5-HT and the immune system
    • G.P. Ahern 5-HT and the immune system Curr. Opin. Pharmacol. 11 2011 1 5
    • (2011) Curr. Opin. Pharmacol. , vol.11 , pp. 1-5
    • Ahern, G.P.1
  • 6
    • 77952570888 scopus 로고    scopus 로고
    • Regulation of serotonin receptor function in the nervous system by lipid rafts and adaptor proteins
    • K. Bjork, B. Sjogren, and P. Svenningsson Regulation of serotonin receptor function in the nervous system by lipid rafts and adaptor proteins Exp. Cell Res. 316 2010 1351 1356
    • (2010) Exp. Cell Res. , vol.316 , pp. 1351-1356
    • Bjork, K.1    Sjogren, B.2    Svenningsson, P.3
  • 7
    • 84894361065 scopus 로고    scopus 로고
    • G-protein signaling, lipid rafts and the possible sites of action for the antidepressant effects of N-3 polyunsaturated fatty acids
    • (Epub ahead of print)
    • A.H. Cszysz, and M.M. Rasenick G-protein signaling, lipid rafts and the possible sites of action for the antidepressant effects of N-3 polyunsaturated fatty acids CNS Neurol. Disord. Drug Targets 2013 (Epub ahead of print)
    • (2013) CNS Neurol. Disord. Drug Targets
    • Cszysz, A.H.1    Rasenick, M.M.2
  • 8
    • 53449087663 scopus 로고    scopus 로고
    • Behavioral and serotonergic consequences of decreasing or increasing hippocampus brain-derived neurotrophic factor protein levels in mice
    • T. Deltheil, B.P. Guiard, and J. Cerdan et al. Behavioral and serotonergic consequences of decreasing or increasing hippocampus brain-derived neurotrophic factor protein levels in mice Neuropharmacology 55 2008 1006 1014
    • (2008) Neuropharmacology , vol.55 , pp. 1006-1014
    • Deltheil, T.1    Guiard, B.P.2    Cerdan, J.3
  • 9
    • 77953539546 scopus 로고    scopus 로고
    • Human serotonin transporter expression during megakaryocytic differentiation of MEG-01 cells
    • G. Giannaccinni, L. Betti, and L. Palego et al. Human serotonin transporter expression during megakaryocytic differentiation of MEG-01 cells Neurochem. Res. 35 2010 628 635
    • (2010) Neurochem. Res. , vol.35 , pp. 628-635
    • Giannaccinni, G.1    Betti, L.2    Palego, L.3
  • 10
    • 0036154094 scopus 로고    scopus 로고
    • Mechanisms of ligand-induced desensitization of the 5-hydroxytryptamine (2A) receptor
    • N.R. Hanley, and J.G. Hensler Mechanisms of ligand-induced desensitization of the 5-hydroxytryptamine (2A) receptor J. Pharmacol. Exp. Ther. 300 2002 468 477
    • (2002) J. Pharmacol. Exp. Ther. , vol.300 , pp. 468-477
    • Hanley, N.R.1    Hensler, J.G.2
  • 11
    • 69149100929 scopus 로고    scopus 로고
    • Cluster size regulates protein sorting in the immunological synapses
    • N.C. Hartman, J.A. Nye, and J.T. Groves Cluster size regulates protein sorting in the immunological synapses Proc. Natl. Acad. Sci. U. S. A. 106 2009 12729 12734
    • (2009) Proc. Natl. Acad. Sci. U. S. A. , vol.106 , pp. 12729-12734
    • Hartman, N.C.1    Nye, J.A.2    Groves, J.T.3
  • 12
    • 78651422980 scopus 로고    scopus 로고
    • Regulation of antigen-specific CTL and Th1 cell activation through 5-hydroxytryptamine 2A receptor
    • M. Inoue, T. Okazaki, and T. Kitazono et al. Regulation of antigen-specific CTL and Th1 cell activation through 5-hydroxytryptamine 2A receptor Int. Immunopharmacol. 11 2011 67 73
    • (2011) Int. Immunopharmacol. , vol.11 , pp. 67-73
    • Inoue, M.1    Okazaki, T.2    Kitazono, T.3
  • 13
    • 0037831023 scopus 로고    scopus 로고
    • The epidemiology of major depressive disorder. Results from the national comorbidity survey replication (NCS-R)
    • R.C. Kessler, P. Berglun, and O. Demler et al. The epidemiology of major depressive disorder. Results from the national comorbidity survey replication (NCS-R) J. Am. Med. Assoc. 289 2003 3095 3105
    • (2003) J. Am. Med. Assoc. , vol.289 , pp. 3095-3105
    • Kessler, R.C.1    Berglun, P.2    Demler, O.3
  • 14
    • 77958068373 scopus 로고    scopus 로고
    • The concept of depression as a dysfunction of the immune system
    • B.E. Leonard The concept of depression as a dysfunction of the immune system Curr. Immunol. Rev. 6 2010 205 212
    • (2010) Curr. Immunol. Rev. , vol.6 , pp. 205-212
    • Leonard, B.E.1
  • 15
    • 80755153592 scopus 로고    scopus 로고
    • Inflammatory biomarkers in depression: An opportunity of novel therapeutic intervention
    • M. Li, J.K. Soczynska, and S.H. Kennedy Inflammatory biomarkers in depression: an opportunity of novel therapeutic intervention Curr. Psychiatry Rep. 13 2011 316 320
    • (2011) Curr. Psychiatry Rep. , vol.13 , pp. 316-320
    • Li, M.1    Soczynska, J.K.2    Kennedy, S.H.3
  • 16
    • 77951667861 scopus 로고    scopus 로고
    • CRF receptor 1 regulates anxiety behaviour via sensitization of 5-HT2 receptor signaling
    • A.C. Magalhaes, K.D. Holmes, and L.B. Dale et al. CRF receptor 1 regulates anxiety behaviour via sensitization of 5-HT2 receptor signaling Nat. Neurosci. 13 2010 622 629
    • (2010) Nat. Neurosci. , vol.13 , pp. 622-629
    • Magalhaes, A.C.1    Holmes, K.D.2    Dale, L.B.3
  • 17
    • 63449122724 scopus 로고    scopus 로고
    • Inflammation and its discontents: The role of cytokines in the pathophysiology of major depression
    • A.H. Miller, V. Malestic, and C.L. Raison Inflammation and its discontents: the role of cytokines in the pathophysiology of major depression Biol. Psychiatry 65 2009 732 741
    • (2009) Biol. Psychiatry , vol.65 , pp. 732-741
    • Miller, A.H.1    Malestic, V.2    Raison, C.L.3
  • 18
    • 34547410247 scopus 로고    scopus 로고
    • Consensus paper of the WFSBP task force on biological markers: Biological markers in depression
    • R. Mossner, O. Mikova, and E. Koutsilieri et al. Consensus paper of the WFSBP task force on biological markers: biological markers in depression World J. Biol. Psychiatry 8 2007 141 174
    • (2007) World J. Biol. Psychiatry , vol.8 , pp. 141-174
    • Mossner, R.1    Mikova, O.2    Koutsilieri, E.3
  • 19
    • 0025345457 scopus 로고
    • Platelet serotonin-2 receptor binding sites in depression and suicide
    • G.N. Pandey, S.C. Pandey, and P.G. Janicak et al. Platelet serotonin-2 receptor binding sites in depression and suicide Biol. Psychiatry 28 1990 215 222
    • (1990) Biol. Psychiatry , vol.28 , pp. 215-222
    • Pandey, G.N.1    Pandey, S.C.2    Janicak, P.G.3
  • 20
    • 0029045106 scopus 로고
    • Platelet serotonoin-2A receptors; A potential biological marker for suicidal behavior
    • G.N. Pandey, S.C. Pandey, and Y. Dwivedi et al. Platelet serotonoin-2A receptors; a potential biological marker for suicidal behavior Am. J. Psychiatry 152 1995 850 855
    • (1995) Am. J. Psychiatry , vol.152 , pp. 850-855
    • Pandey, G.N.1    Pandey, S.C.2    Dwivedi, Y.3
  • 21
    • 30544445602 scopus 로고    scopus 로고
    • Cytokines sing the blues: Inflammation and the pathogenesis of depression
    • C.L. Raison, L. Capuron, and A.H. Miller Cytokines sing the blues: inflammation and the pathogenesis of depression Trends Immunol. 27 2006 24 31
    • (2006) Trends Immunol. , vol.27 , pp. 24-31
    • Raison, C.L.1    Capuron, L.2    Miller, A.H.3
  • 23
    • 84857367666 scopus 로고    scopus 로고
    • Serotonin transporter clustering in blood lymphocytes as a putative biomarker of therapeutic efficacy in major depressive disorder
    • T. Rivera-Baltanas, J.M. Olivares, and M. Calado-Otero et al. Serotonin transporter clustering in blood lymphocytes as a putative biomarker of therapeutic efficacy in major depressive disorder J. Affect. Disord. 137 2012 46 55
    • (2012) J. Affect. Disord. , vol.137 , pp. 46-55
    • Rivera-Baltanas, T.1    Olivares, J.M.2    Calado-Otero, M.3
  • 25
    • 33751338530 scopus 로고    scopus 로고
    • Acute and long-term outcomes in depressed outpatients requiring one or several treatment steps: A STARD report
    • A.J. Rush, M.H. Trivedi, and S.R. Wisniewski et al. Acute and long-term outcomes in depressed outpatients requiring one or several treatment steps: a STARD report Am. J. Psychiatry 163 2006 1905 1917
    • (2006) Am. J. Psychiatry , vol.163 , pp. 1905-1917
    • Rush, A.J.1    Trivedi, M.H.2    Wisniewski, S.R.3
  • 26
    • 84896825306 scopus 로고    scopus 로고
    • Synaptic integration in the central nervous system
    • E.R. Kandel, J.H. Schwartz, T.M. Jessell, 5th ed. McGraw-Hill New York
    • S.A. Siegelbaum, E.R. Kandel, and R. Yuste Synaptic integration in the central nervous system E.R. Kandel, J.H. Schwartz, T.M. Jessell, Principles of Neural Science 5th ed. 2013 McGraw-Hill New York 210 235
    • (2013) Principles of Neural Science , pp. 210-235
    • Siegelbaum, S.A.1    Kandel, E.R.2    Yuste, R.3
  • 28
    • 0034456505 scopus 로고    scopus 로고
    • MRNA expression of serotonin receptors in cells of the immune tissue of the rat
    • J. Stefulj, B. Jernej, and L. Cicin-Sain et al. mRNA expression of serotonin receptors in cells of the immune tissue of the rat Brain Behav. Immun. 14 2000 219 224
    • (2000) Brain Behav. Immun. , vol.14 , pp. 219-224
    • Stefulj, J.1    Jernej, B.2    Cicin-Sain, L.3
  • 30
    • 0037453204 scopus 로고    scopus 로고
    • 5-HT2A and 5-HT2C receptors and their atypical regulation profiles
    • D. Van Oekelen, W.H. Luyten, and J.E. Leysen 5-HT2A and 5-HT2C receptors and their atypical regulation profiles Life Sci. 72 2003 2429 2449
    • (2003) Life Sci. , vol.72 , pp. 2429-2449
    • Van Oekelen, D.1    Luyten, W.H.2    Leysen, J.E.3
  • 31
    • 49549119585 scopus 로고    scopus 로고
    • Treatment-resistant depression: Critique of current approaches
    • C. Wijeratne, and P. Sachdev Treatment-resistant depression: critique of current approaches Aust. N. Z. J. Psychiatry 42 2008 751 762
    • (2008) Aust. N. Z. J. Psychiatry , vol.42 , pp. 751-762
    • Wijeratne, C.1    Sachdev, P.2
  • 32
    • 0037484186 scopus 로고    scopus 로고
    • 2A serotonin receptors regulates receptor trafficking and signal transduction
    • 2A serotonin receptors regulates receptor trafficking and signal transduction J. Biol. Chem. 278 2003 2190121908
    • (2003) J. Biol. Chem. , vol.278 , pp. 2190121908
    • Xia, Z.1    Gray, J.A.2    Compton-Topth, B.A.3
  • 33
    • 80053146959 scopus 로고    scopus 로고
    • Antagonist functional selectivity: 5-HT2A serotonin receptor antagonists differentially regulate 5-HT2A protein level in vivo
    • P.N. Yadav, W.K. Kroeze, and M.S. Farrell et al. Antagonist functional selectivity: 5-HT2A serotonin receptor antagonists differentially regulate 5-HT2A protein level in vivo J. Pharmacol. Exp. Ther. 339 2011 99 105
    • (2011) J. Pharmacol. Exp. Ther. , vol.339 , pp. 99-105
    • Yadav, P.N.1    Kroeze, W.K.2    Farrell, M.S.3
  • 34
    • 33748268092 scopus 로고    scopus 로고
    • Expression of mRNA for multiple serotonin (5-HT) receptor types/subtypes by the peripheral blood mononuclear cells of rhesus macaques
    • G.B. Yang, C.L. Qiu, and H. Zhao et al. Expression of mRNA for multiple serotonin (5-HT) receptor types/subtypes by the peripheral blood mononuclear cells of rhesus macaques J. Neuroimmunol. 178 2006 24 29
    • (2006) J. Neuroimmunol. , vol.178 , pp. 24-29
    • Yang, G.B.1    Qiu, C.L.2    Zhao, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.