Penetration of tamoxifen citrate loaded ethosomes and liposomes across human skin: A comparative study with confocal laser scanning microscopy

Current Drug Delivery

Volumn 11, Issue 3, 2014, Pages 332-337

  Sarwa, Khomendra K ^a   Suresh, Preeti K ^b   Rudrapal, Mithun ^c   Verma, Vinod K ^a  

^a DIBRUGARH UNIVERSITY   (India)

^b PT RAVISHANKAR SHUKLA UNIVERSITY   (India)

^c Aditya Pharmacy College   (India)

Author keywords

CLSM; Ethosomes; Liposomes; Tamoxifen citrate

Indexed keywords

DRUG CARRIER; ETHOSOME; LIPOSOME; TAMOXIFEN CITRATE; UNCLASSIFIED DRUG; ANTIESTROGEN; TAMOXIFEN;

ADULT; ARTICLE; CADAVER; COMPARATIVE STUDY; CONFOCAL LASER MICROSCOPY; DIFFUSION; FLUORESCENCE; FRANZ DIFFUSION CELL; HUMAN; HUMAN TISSUE; MALE; PARTICLE SIZE; PRIORITY JOURNAL; SKIN PENETRATION; SKIN PERMEABILITY; SKINFOLD THICKNESS; TRANSDERMAL DRUG DELIVERY SYSTEM; ZETA POTENTIAL; CONFOCAL MICROSCOPY; IN VITRO STUDY; INTRADERMAL DRUG ADMINISTRATION; METABOLISM; SKIN; SKIN ABSORPTION;

ADMINISTRATION, CUTANEOUS; ADULT; ESTROGEN ANTAGONISTS; HUMANS; IN VITRO TECHNIQUES; LIPOSOMES; MALE; MICROSCOPY, CONFOCAL; SKIN; SKIN ABSORPTION; TAMOXIFEN;

EID: 84899046001     PISSN: 15672018     EISSN: 18755704     Source Type: Journal    
DOI: 10.2174/1567201811666140115113127     Document Type: Article

References (18)

1. Jagdale, S.C.; Shah, T.P.; Kuchekar, B.S.; Chabukswar, A.R.; Baviskar, D.T. Cancer nanotechnology. Asian J. Pharm., 2009, 3, 4-8.
2. Gragnani, A.; Warde, M.; Furtado, F.; Ferreira, M.; Topical tamoxifen therapy in hypertrophic scars or keloids in burns. Arch. Dermatol. Res., 2010, 302, 1-4.
3. Hu, D.; Hughes, M.A.; Cherry, G.W. Topical tamoxifen-a potential therapeutic regime in treating excessive dermal scarring. Br. J. Plast. Surg., 1998, 5, 462-469.
4. De Lima, G.R.; Facina, G.; Shida, J.Y.; Chein, Mbc.; Tanaka, P.; Dardes, R.C.; Jordan, V.C.; Gebrim, L.H. Effects of low dose tamoxifen on normal breast tissue from premenopausal women. Eur. J. Cancer, 2003, 39, 891-898.
5. Gao, S.; Singh, J. In vitro percutaneous absorption enhancement of a lipophilic drug tamoxifen by terpenes. J. Control Release., 1998, 51, 193-199.
6. Mezei, M.; Gulasekharam, V. Liposomes-a selective drug delivery system for the topical route of administration, lotion dosage form. Life Sci., 1980, 26, 1473-1477.
7. Sharma, V.K.; Sarwa, K.K.; Mazumder, B. Fluidity enhancement: a critical factor for performance of liposomal transdermal drug delivery system. J. Liposome. Res., 2013 (Early online DOI: 10.3109/ 08982104.2013.847956).
8. Shao, M.; Sun, S.; Li, M.; Li, B.; Yu, H.; Shen, Z.; Ren, Y.; Hao, Z.; Chang, N.; Peng, H.; Yang, B. The liposomal daunorubicin plus tamoxifen: improving the stability, uptake, and biodistribution of carriers. J. Liposome Res., 2012, 22, 168-176.
9. Sarwa, K.K.; Suresh, P.K.; Debnath, M.; Ahmad, M.Z. Tamoxifen citrate loaded ethosomes for transdermal drug delivery system: preparation and characterization. Curr. Drug Deliv., 2013, 10, 466-476.
10. Bhatia, A.; Kumar, R.; Katare, O.P. Tamoxifen in topical liposomes: development, characterization and in-vitro evaluation. Int. J. Pharmacy Pharm. Sci., 2004, 7, 252-259.
11. Sarwa, K.K.; Mazumder, B.; Rudrapal, M.; Verma, V. Potential of capsaicin-loaded transfersomes in arthritic rats. Drug Deliv., 2013. Early Online: 1-9. DOI: 10.3109/10717544.2013.871601.
12. Heard, C.M.; Monk, B.W.; Modley, A.J. Binding of primaquine to epidermal membranes and keratin. Int. J. Pharm., 2003, 257, 237-244.
13. De Medina, P.; Favre, G.; Poirot, M.; multiple targeting by the antitumor drug tamoxifen: a structure-activity study. Curr. Med. Chem. Anti. Canc. Agents, 2004, 4, 491-508.
14. Sarwa, K.K.; Rudrapal, M.; Mazumder, B. Topical ethosomal capsaicin attenuates edema and nociception in arthritic rats. Drug Deliv., 2013, Early Online: 1–10, DOI: 10.3109/10717544.2013.861041.
15. Kuijk-Meuwissen, M.E.; Junginger, H.E.; Bouwstra, J.A. Interactions between liposomes and human skin in vitro, a confocal laser scanning microscopy study. Biochim. Biophys. Acta., 1998, 1371, 31-39.
16. Dayan, N.; Touitou, E. Carrier for skin delivery of trihexyphenidyl HCl: Ethosomes vs liposomes. Biomaterials., 2000, 21, 1879-1885.
17. Kirjavainen, M.; Urtti, A.; Valjakka-Koskela, R.; Kiesvaara, J.; Monkkonen, J. Liposome-skin interactions and their effects on the skin permeation of drugs. Eur. J. Pharm. Sci., 1999, 7, 279-286.
18. Sarwa, K.K.; Das, P.J.; Mazumder, B. A Nanovesicle Topical Formulation of Bhut Jolokia (Hottest Capsicum): A potential antiarthritic medicine. Expert Opin. Drug. Deliv., 2014, 11, 661-676.