Topical ethosomal capsaicin attenuates edema and nociception in arthritic rats

Drug Delivery

Volumn 22, Issue 8, 2015, Pages 1043-1052

  Kumar Sarwa, Khomendra ^a   Rudrapal, Mithun ^a,b   Mazumder, Bhaskar ^a  

^a DIBRUGARH UNIVERSITY   (India)

^b Aditya Pharmacy College   (India)

Author keywords

Arthritis; Capsaicin; Ethosomes; Transdermal

Indexed keywords

CAPSAICIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTINOCICEPTION; ARTHRITIS; ARTICLE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG FORMULATION; GEL; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; LONG TERM CARE; MALE; NOCICEPTION; NONHUMAN; PAW EDEMA; PHASE TRANSITION; PRIORITY JOURNAL; RAT; SKIN IRRITATION; ZETA POTENTIAL;

EID: 84949548952     PISSN: 10717544     EISSN: 15210464     Source Type: Journal    
DOI: 10.3109/10717544.2013.861041     Document Type: Article

References (54)

1. Aranda FJ, Jos V, Comez-Fernfindez JC. Capsaicin affects the structure and phase organization of phospholipid membranes. Biochim Biophy Acta 1995; 1234: 225-34
2. Backonja MM, Malan TP, Vanhove GF, Tobias JK. NGX-4010, a high-concentration capsaicin patch, for the treatment of postherpetic neuralgia: a randomized, double-blind, controlled study with an open-label extension. Pain Med 2010; 1: 600-8
3. Donnerer J, Amann R, Schuligoi R, Lembeck F. Absorption and metabolism of capsaicinoids following intragastric administration in rats. Naunyn Schmiedebergs Arch Pharmacol 1990; 342: 357-61
4. Fusco BM, Giacovazzo M. Peppers and pain: the promise of capsaicin. Drugs 1997; 53: 909-14
5. Gebhardt M, Reuter A, Knopf B. Allergic contact dermatitis from topical diclofenac. Contact Dermatitis 1994; 30: 183-4
6. Jain SN, Jain D, Bhadra A, et al. Transdermal delivery of an analgesic agent using elastic liposomes: preparation, characterization and performance evaluation. Curr Drug Deliv 2005; 2: 223-33
7. Kaithwas G, Gautam R, Jachak SM, Saklai A. Antiarthritic effect of Ajga bracteosa Wall ex Benth. in acute and chronic models of arthritis in albino rats. Asian Pac J Trop Biomed 2012; 2: 185-8
8. Kawada T, Watanabe T, Katsura K, et al. J Chromatogr 1985; 329: 99-105
9. Kuijk-Meuwissen ME, Junginger HE, Bouwstra JA. Interactions between liposomes and human skin in vitro, a confocal laser scanning microscopy study. Biochim Biophys Acta 1998; 1371: 31-9
10. Lariviere WR, Melzack R. The bee venom test: a new tonic-pain test. Pain 1996; 66: 271-7
11. Lee J, Kim KA, Jeong S, et al. Anti-inflammatory, anti-nociceptive, and anti-psychiatric effects by the rhizomes of Alpinia officinarum on complete Freund's adjuvant-induced arthritis in rats. J Ethnopharmacol 2009; 126: 258-64
12. Lodzki M, Godin B, Rakou L, et al. Cannabidiol-transdermal delivery and anti-inflammatory effect in a murine model. J Control Release 2003; 93: 377-87
13. Newbould BB. Chemotherapy of arthritis induced in rats by mycobacterial adjuvants. Br J Pharmacol 1963; 21: 127-36
14. Porreca E, Sergi R, Baccante G, et al. Peripheral blood mononuclear cell production of interleukin-8 and IL-8-dependent neutrophil function in hypercholesterolemic patients. Atherosclerosis 1999; 146: 345-50
15. Raghavendra V, Tanga F, DeLeo JA. Inhibition of microglial activation attenuates the development but not existing hypersensitivity in a rat model of neuropathy. J Pharmacol Exp Ther 2003; 306: 624-30
16. Sarwa KK, Mazumder B, Rudrapal M, Verma VK. Potential of capsaicin-loaded transfersomes in arthritic rats. Drug Deliv 2013a;Early Online: 1-9. doi: 10.3109/10717544.2013.871601
17. Sarwa KK, Suresh PK, Debnath M, Ahmad MZ. Tamoxifen citrate loaded ethosomes for transdermal drug delivery system: preparation and characterization. Curr Drug Deliv 2013 b; 10: 466-76
18. Severcan F, Sahin I, Kazanci N. Melatonin strongly interacts with zwitterionic model membranes-evidence from Fourier transform infrared spectroscopy and differential scanning calorimetry. Biochim Biophys Acta. 2005; 1668: 215-22
19. Sharma VK, Sarwa KK, Mazumder B. Fluidity enhancement: a critical factor for performance of liposomal transdermal drug delivery system. J Liposome Res 2013;published online 25 October 2013. doi: 10.3109/08982104.2013.847956
20. Simionescus M. Ciba Found. Symp 71 (1980)
21. Tappeiner C, Flueckiger F, Boehnke M, et al. Effect of topical anesthetic agents and ethanol on corneoepithelial wound healing in an ex vivo whole-globe porcine model. J Cataract Refract Surg 2012; 38: 519-24
22. Touitou E, Dayan N, Bergelson L, et al. Ethosomes-novel vesicular carriers for enhanced delivery: characterization and skin penetration properties. J Control Release 2000; 65: 403-18
23. Tsuchiya H. Biphasic membrane effects of capsaicin, an active component in Capsicum species. J Ethnopharmacol 2001; 75: 295-9
24. Verma DD, Fahr A. Synergistic penetration enhancement effect off ethanol and phospholipids on the topical delivery of cyclosporine A. J Controlled Release 2004; 97: 55-66
25. Watkins LR, Milligan ED, Maier SF. Glial activation: a driving force for pathological pain. Trends Neurosci 2001; 24: 450-5
26. Winter CA, Risley EA, Nuss GW. Carrageenin-induced edema in the hind paw of the rat as an assay for anti-inflammatory drugs. Proc Soc Exp Biol Med III 1962; 544-7
27. Zhang W, Moskowitz RW, Nuki G, et al. OARSI recommendations for the management of hip and knee osteoarthritis, part II: OARSI evidence based, expert consensus guidelines, Osteoarthr. Cartil 2008; 16: 137-62
28. Aranda FJ, Jos V, Comez-Fernfindez JC. Capsaicin affects the structure and phase organization of phospholipid membranes. Biochim Biophy Acta 1995; 1234: 225-34
29. Backonja MM, Malan TP, Vanhove GF, Tobias JK. NGX-4010, a high-concentration capsaicin patch, for the treatment of postherpetic neuralgia: a randomized, double-blind, controlled study with an open-label extension. Pain Med 2010; 1: 600-8
30. Donnerer J, Amann R, Schuligoi R, Lembeck F. Absorption and metabolism of capsaicinoids following intragastric administration in rats. Naunyn Schmiedebergs Arch Pharmacol 1990; 342: 357-61
31. Fusco BM, Giacovazzo M. Peppers and pain: the promise of capsaicin. Drugs 1997; 53: 909-14
32. Gebhardt M, Reuter A, Knopf B. Allergic contact dermatitis from topical diclofenac. Contact Dermatitis 1994; 30: 183-4
33. Jain SN, Jain D, Bhadra A, et al. Transdermal delivery of an analgesic agent using elastic liposomes: preparation, characterization and performance evaluation. Curr Drug Deliv 2005; 2: 223-33
34. Kaithwas G, Gautam R, Jachak SM, Saklai A. Antiarthritic effect of Ajga bracteosa Wall ex Benth. in acute and chronic models of arthritis in albino rats. Asian Pac J Trop Biomed 2012; 2: 185-8
35. Kawada T, Watanabe T, Katsura K, et al. J Chromatogr 1985; 329: 99-105
36. Kuijk-Meuwissen ME, Junginger HE, Bouwstra JA. Interactions between liposomes and human skin in vitro, a confocal laser scanning microscopy study. Biochim Biophys Acta 1998; 1371: 31-9
37. Lariviere WR, Melzack R. The bee venom test: a new tonic-pain test. Pain 1996; 66: 271-7
38. Lee J, Kim KA, Jeong S, et al. Anti-inflammatory, anti-nociceptive, and anti-psychiatric effects by the rhizomes of Alpinia officinarum on complete Freund's adjuvant-induced arthritis in rats. J Ethnopharmacol 2009; 126: 258-64
39. Lodzki M, Godin B, Rakou L, et al. Cannabidiol-transdermal delivery and anti-inflammatory effect in a murine model. J Control Release 2003; 93: 377-87
40. Newbould BB. Chemotherapy of arthritis induced in rats by mycobacterial adjuvants. Br J Pharmacol 1963; 21: 127-36
41. Porreca E, Sergi R, Baccante G, et al. Peripheral blood mononuclear cell production of interleukin-8 and IL-8-dependent neutrophil function in hypercholesterolemic patients. Atherosclerosis 1999; 146: 345-50
42. Raghavendra V, Tanga F, DeLeo JA. Inhibition of microglial activation attenuates the development but not existing hypersensitivity in a rat model of neuropathy. J Pharmacol Exp Ther 2003; 306: 624-30
43. Sarwa KK, Mazumder B, Rudrapal M, Verma VK. Potential of capsaicin-loaded transfersomes in arthritic rats. Drug Deliv 2013a;Early Online: 1-9. doi: 10.3109/10717544.2013.871601
44. Sarwa KK, Suresh PK, Debnath M, Ahmad MZ. Tamoxifen citrate loaded ethosomes for transdermal drug delivery system: preparation and characterization. Curr Drug Deliv 2013 b; 10: 466-76
45. Severcan F, Sahin I, Kazanci N. Melatonin strongly interacts with zwitterionic model membranes-evidence from Fourier transform infrared spectroscopy and differential scanning calorimetry. Biochim Biophys Acta. 2005; 1668: 215-22
46. Sharma VK, Sarwa KK, Mazumder B. Fluidity enhancement: a critical factor for performance of liposomal transdermal drug delivery system. J Liposome Res 2013;published online 25 October 2013. doi: 10.3109/08982104.2013.847956
47. Simionescus M. Ciba Found. Symp 71 (1980)
48. Tappeiner C, Flueckiger F, Boehnke M, et al. Effect of topical anesthetic agents and ethanol on corneoepithelial wound healing in an ex vivo whole-globe porcine model. J Cataract Refract Surg 2012; 38: 519-24
49. Touitou E, Dayan N, Bergelson L, et al. Ethosomes-novel vesicular carriers for enhanced delivery: characterization and skin penetration properties. J Control Release 2000; 65: 403-18
50. Tsuchiya H. Biphasic membrane effects of capsaicin, an active component in Capsicum species. J Ethnopharmacol 2001; 75: 295-9
51. Verma DD, Fahr A. Synergistic penetration enhancement effect off ethanol and phospholipids on the topical delivery of cyclosporine A. J Controlled Release 2004; 97: 55-66
52. Watkins LR, Milligan ED, Maier SF. Glial activation: a driving force for pathological pain. Trends Neurosci 2001; 24: 450-5
53. Winter CA, Risley EA, Nuss GW. Carrageenin-induced edema in the hind paw of the rat as an assay for anti-inflammatory drugs. Proc Soc Exp Biol Med III 1962; 544-7
54. Zhang W, Moskowitz RW, Nuki G, et al. OARSI recommendations for the management of hip and knee osteoarthritis, part II: OARSI evidence based, expert consensus guidelines, Osteoarthr. Cartil 2008; 16: 137-62