메뉴 건너뛰기




Volumn 24, Issue 2, 2014, Pages 83-89

Fluidity enhancement: A critical factor for performance of liposomal transdermal drug delivery system

Author keywords

Flexibility; Fluidizing agents; Lipid bilayer; Lipid vesicles

Indexed keywords

ALCOHOL; LIPID; LIPOSOME; NIOSOME; PENETRATION ENHANCING AGENT; PHOSPHOLIPID; POLYCARBONATE; STEARIC ACID; SURFACTANT; PHOSPHATIDYLCHOLINE;

EID: 84903774851     PISSN: 08982104     EISSN: 15322394     Source Type: Journal    
DOI: 10.3109/08982104.2013.847956     Document Type: Review
Times cited : (32)

References (88)
  • 1
    • 0002056886 scopus 로고
    • Preparation and use of liposomes as models of biological membranes
    • Korn ND, ed New York: Plenum
    • Bangham AD, Hill MW, Miller NGA. (1974). Preparation and use of liposomes as models of biological membranes. In: Korn ND, ed. Methods in Membrane Biology. Vol. 1. New York: Plenum, 1-68.
    • (1974) Methods in Membrane Biology. , vol.1 , pp. 1-68
    • Bangham, A.D.1    Hill, M.W.2    Miller, N.G.A.3
  • 2
    • 0034902043 scopus 로고    scopus 로고
    • Novel mechanisms and devices to enable successful transdermal drug delivery
    • DOI 10.1016/S0928-0987(01)00167-1, PII S0928098701001671
    • Barry BW. (2001). Novel mechanisms and devices to enable successful transdermal drug delivery. Eur J Pharm Sci 14:101-14. (Pubitemid 32737532)
    • (2001) European Journal of Pharmaceutical Sciences , vol.14 , Issue.2 , pp. 101-114
    • Barry, B.W.1
  • 3
    • 0023597397 scopus 로고
    • Mode of action of penetration enhancers in human skin
    • DOI 10.1016/0168-3659(87)90066-6
    • Barry BW. (1987). Mode of action of penetration enhancers in human skin. J Control Release 6:85-97. (Pubitemid 18017724)
    • (1987) Journal of Controlled Release , vol.6 , Issue.SPEC.NO. , pp. 85-97
    • Barry, B.W.1
  • 4
    • 0015927357 scopus 로고
    • Single bilayer liposomes prepared without sonication
    • Batzri S, Korn ED. (1973). Single bilayer liposomes prepared without sonication. Biochim Biophys Acta 298:1015-19.
    • (1973) Biochim Biophys Acta , vol.298 , pp. 1015-1019
    • Batzri, S.1    Korn, E.D.2
  • 5
    • 77950491967 scopus 로고    scopus 로고
    • Elastic liposomes for topical and transdermal drug delivery
    • Benson HA. (2010). Elastic liposomes for topical and transdermal drug delivery. Methods Mol Biol 605:77-86.
    • (2010) Methods Mol Biol , vol.605 , pp. 77-86
    • Benson, H.A.1
  • 6
    • 0037136041 scopus 로고    scopus 로고
    • Ultradeformable lipid vesicles can penetrate the skin and other semi-permeable barriers unfragmented. Evidence from double label CLSM experiments and direct size measurements
    • DOI 10.1016/S0005-2736(02)00401-7, PII S0005273602004017
    • Cevc G, Schätzlein A, Richardsen H. (2002). Ultra deformable lipid vesicles can penetrate the skin and other semi-permeable barriers unfragmented. Evidence from double label CLSM experiments and direct size measurements. Biochim Biophys Acta 1564:21-30. (Pubitemid 34717865)
    • (2002) Biochimica et Biophysica Acta - Biomembranes , vol.1564 , Issue.1 , pp. 21-30
    • Cevc, G.1    Schatzlein, A.2    Richardsen, H.3
  • 7
    • 77957043061 scopus 로고
    • Material transport across permeability barriers by means of lipid vesicles
    • Lipowsky RSE, ed Amsterdam: Elsevier
    • Cevc G. (1995). Material transport across permeability barriers by means of lipid vesicles. In: Lipowsky RSE, ed. Handbook of Biological Physics. Amsterdam: Elsevier, 465-90.
    • (1995) Handbook of Biological Physics , pp. 465-490
    • Cevc, G.1
  • 8
    • 0030470587 scopus 로고    scopus 로고
    • Transfersomes, liposomes and other lipid suspensions on the skin: Permeation enhancement, vesicle penetration, and transdermal drug delivery
    • Cevc G. (1996). Transfersomes, liposomes and other lipid suspensions on the skin: permeation enhancement, vesicle penetration, and transdermal drug delivery. Crit Rev Ther Drug Carrier Syst 13: 257-388. (Pubitemid 27024259)
    • (1996) Critical Reviews in Therapeutic Drug Carrier Systems , vol.13 , Issue.3-4 , pp. 257-388
    • Cevc, G.1
  • 9
    • 0026508985 scopus 로고
    • Lipid vesicles penetrate into intact skin owing to the transdermal osmotic gradients and hydration force
    • Cevc G, Blume G. (1992). Lipid vesicles penetrate into intact skin owing to the transdermal osmotic gradients and hydration force. Biochim Biophys Acta 1104:226-32.
    • (1992) Biochim Biophys Acta , vol.1104 , pp. 226-232
    • Cevc, G.1    Blume, G.2
  • 10
    • 0041704830 scopus 로고    scopus 로고
    • Biological activity and characteristics of triamcinolone-acetonide formulated with the self-regulating drug carriers, Transfersomes®
    • DOI 10.1016/S0005-2736(03)00172-X
    • Cevc G, Blume G. (2003). Biological activity and characteristics of triamcinolone-acetonide formulated with the self-regulating drug carriers, transfersomes. Biochim Biophys Acta 1614:156-64. (Pubitemid 36929979)
    • (2003) Biochimica et Biophysica Acta - Biomembranes , vol.1614 , Issue.2 , pp. 156-164
    • Cevc, G.1    Blume, G.2
  • 11
    • 0031047776 scopus 로고    scopus 로고
    • Transfersomes-mediated transepidermal delivery improves the regio-specificity and biological activity of corticosteroids in vivo
    • Cevc G, Blume G, Schatzlein A. (1997). Transfersomes-mediated transepidermal delivery improves the regio-specificity and biological activity of corticosteroids in vivo. J Control Release 45:211-26.
    • (1997) J Control Release , vol.45 , pp. 211-226
    • Cevc, G.1    Blume, G.2    Schatzlein, A.3
  • 14
    • 0017101625 scopus 로고
    • Large volume liposomes by an ether vaporization method
    • Deamer D, Bangham AD. (1976). Large volume liposomes by an ether vaporization method. Biochim Biophys Acta 443:629-34.
    • (1976) Biochim Biophys Acta , vol.443 , pp. 629-634
    • Deamer, D.1    Bangham, A.D.2
  • 15
    • 40649104527 scopus 로고    scopus 로고
    • Temoporfin-loaded invasomes: Development, characterization and in vitro skin penetration studies
    • Dragicevic-Curic N, Scheglmann D, Albrecht V, Fahr A. (2008). Temoporfin-loaded invasomes: development, characterization and in vitro skin penetration studies. J Control Release 127:59-69.
    • (2008) J Control Release , vol.127 , pp. 59-69
    • Dragicevic-Curic, N.1    Scheglmann, D.2    Albrecht, V.3    Fahr, A.4
  • 16
    • 62349100156 scopus 로고    scopus 로고
    • Development of different temoporfin-loaded invasomes-novel nano-carriers of temoporfin: Characterization, stability and in vitro skin penetration studies
    • Dragicevic-Curic N, Scheglmann D, Albrecht V, Fahr A. (2009). Development of different temoporfin-loaded invasomes-novel nano-carriers of temoporfin: characterization, stability and in vitro skin penetration studies. Colloids Surf B Biointerfaces 70:198-206.
    • (2009) Colloids Surf B Biointerfaces , vol.70 , pp. 198-206
    • Dragicevic-Curic, N.1    Scheglmann, D.2    Albrecht, V.3    Fahr, A.4
  • 17
    • 79957521133 scopus 로고    scopus 로고
    • Assessment of fluidity of different invasomes by electron spin resonance and differential scanning calorimetry
    • Dragicevic-Curic N, Friedrich M, Petersen S, et al. (2011). Assessment of fluidity of different invasomes by electron spin resonance and differential scanning calorimetry. Int J Pharm 412:85-94.
    • (2011) Int J Pharm , vol.412 , pp. 85-94
    • Dragicevic-Curic, N.1    Friedrich, M.2    Petersen, S.3
  • 18
    • 33644997763 scopus 로고    scopus 로고
    • Transdermal delivery of a pineal hormone: Melatonin via elastic liposomes
    • Dubey V, Mishra D, Asthana A, Jain NK. (2006). Transdermal delivery of a pineal hormone: melatonin via elastic liposomes. Biomaterials 27: 3491-6.
    • (2006) Biomaterials , vol.27 , pp. 3491-3496
    • Dubey, V.1    Mishra, D.2    Asthana, A.3    Jain, N.K.4
  • 19
    • 47249159342 scopus 로고    scopus 로고
    • Liposomes and skin: From drug delivery to model membranes
    • El Maghraby GM, Barry BW, Williams AC. (2008). Liposomes and skin: from drug delivery to model membranes. Eur J Pharm Sci 34:203-22.
    • (2008) Eur J Pharm Sci , vol.34 , pp. 203-222
    • El Maghraby, G.M.1    Barry, B.W.2    Williams, A.C.3
  • 20
    • 0034758065 scopus 로고    scopus 로고
    • Skin hydration and possible shunt route penetration in controlled estradiol delivery from ultradeformable and standard liposomes
    • DOI 10.1211/0022357011777800
    • El Maghraby GM, Williams AC, Barry BW. (2001). Skin hydration and possible shunt route penetration in controlled estradiol delivery from ultradeformable and standard liposomes. J Pharm Pharmacol 53: 1311-22. (Pubitemid 32982247)
    • (2001) Journal of Pharmacy and Pharmacology , vol.53 , Issue.10 , pp. 1311-1322
    • El Maghraby, G.M.M.1    Williams, A.C.2    Barry, B.W.3
  • 21
    • 0033951387 scopus 로고    scopus 로고
    • Oestradiol skin delivery from ultradeformable liposomes: Refinement of surfactant concentration
    • DOI 10.1016/S0378-5173(99)00441-X, PII S037851739900441X
    • El Maghraby GMM, Williams AC, Barry BW. (2000). Oestradiol skin delivery from ultradeformable liposomes: refinement of surfactant concentration. Int J Pharm 196:63-74. (Pubitemid 30089515)
    • (2000) International Journal of Pharmaceutics , vol.196 , Issue.1 , pp. 63-74
    • El Maghraby, G.M.M.1    Williams, A.C.2    Barry, B.W.3
  • 23
    • 77955980602 scopus 로고    scopus 로고
    • Role of edge activators and surface charge in developing ultradeformable vesicles with enhanced skin delivery
    • El Zaafarany GM, Awad GA, Holayel SM, Mortada ND. (2010). Role of edge activators and surface charge in developing ultradeformable vesicles with enhanced skin delivery. Int J Pharm 397:164-72.
    • (2010) Int J Pharm , vol.397 , pp. 164-172
    • El Zaafarany, G.M.1    Awad, G.A.2    Holayel, S.M.3    Mortada, N.D.4
  • 24
    • 0016639379 scopus 로고
    • Fatty acid chain flexibility in the membranes of normal and transformed fibroblasts
    • Gaffney BJ. (1975). Fatty acid chain flexibility in the membranes of normal and transformed fibroblasts. Proc Natl Acad Sci USA 72: 664-8.
    • (1975) Proc Natl Acad Sci USA , vol.72 , pp. 664-668
    • Gaffney, B.J.1
  • 25
    • 33645562994 scopus 로고    scopus 로고
    • Ethinylestradiol loaded ultraflexible liposomes: Pharmacokinetics and pharmacodynamics
    • Garg M, Mishra D, Agashe H, Jain NK. (2006). Ethinylestradiol loaded ultraflexible liposomes: pharmacokinetics and pharmacodynamics. J Pharm Pharmacol 58:459-68.
    • (2006) J Pharm Pharmacol , vol.58 , pp. 459-468
    • Garg, M.1    Mishra, D.2    Agashe, H.3    Jain, N.K.4
  • 26
    • 0003443075 scopus 로고
    • Differential scanning calorimetry of human stratum corneum: Effect of penetration enhancers azone and DMSO
    • Goodman M, Barry BW. (1983). Differential scanning calorimetry of human stratum corneum: effect of penetration enhancers azone and DMSO. Anal Proc 26:397-8.
    • (1983) Anal Proc , vol.26 , pp. 397-398
    • Goodman, M.1    Barry, B.W.2
  • 27
    • 84986703960 scopus 로고
    • Differential scanning calorimetry (DSC) of human stratum corneum: Effect of azone
    • Goodman M, Barry BW. (1985). Differential scanning calorimetry (DSC) of human stratum corneum: effect of azone. J Pharm Pharmacol 37:80P.
    • (1985) J Pharm Pharmacol , vol.37
    • Goodman, M.1    Barry, B.W.2
  • 28
    • 84986706431 scopus 로고
    • Action of skin permeation enhancers azone, oleic acid and decylmethyl sulphoxide: Permeation and DSC studies
    • Goodman M, Barry BW. (1986). Action of skin permeation enhancers azone, oleic acid and decylmethyl sulphoxide: permeation and DSC studies. J Pharm Pharmacol 38:71P.
    • (1986) J Pharm Pharmacol , vol.38
    • Goodman, M.1    Barry, B.W.2
  • 29
    • 0023680522 scopus 로고
    • Action of penetration enhancers on human skin as assessed by permeation of model drugs 5-fluorouracil and estradiol. I. Infinite dose technique
    • Goodman M, Barry BW. (1988). Action of penetration enhancers on human skin as assessed by permeation of model drugs 5-fluorouracil and estradiol. I. Infinite dose technique. J Invest Dermatol 91:323-7.
    • (1988) J Invest Dermatol , vol.91 , pp. 323-327
    • Goodman, M.1    Barry, B.W.2
  • 30
    • 0021797372 scopus 로고
    • Novel multilayered lipid vesicles: Comparison of physical characteristics of multilamellar liposomes and stable plurilamellar vesicles
    • DOI 10.1021/bi00333a004
    • Gruner SM, Leak RP, Janoff S, Ostro MJ. (1985). Novel multilayered lipid vesicles: comparison of physical characteristics of multilamellar liposomes and stable plurilamellar vesicles. Biochemistry 24: 2833-42. (Pubitemid 15004429)
    • (1985) Biochemistry , vol.24 , Issue.12 , pp. 2833-2842
    • Gruner, S.M.1    Lenk, R.P.2    Janoff, A.S.3    Ostro, M.J.4
  • 32
    • 0642290928 scopus 로고
    • French pressure cell liposomes: Preparation, properties, and potential
    • Gregoriades G, ed Florida: CRC Press, Chapter 4
    • Hamilton RL, Guo LSS. (1984). French pressure cell liposomes: preparation, properties, and potential. In: Gregoriades G, ed. Liposome Technology. Vol. 1. Florida: CRC Press, Chapter 4, 37-49.
    • (1984) Liposome Technology. , vol.1 , pp. 37-49
    • Hamilton, R.L.1    Guo, L.S.S.2
  • 34
    • 33745261719 scopus 로고    scopus 로고
    • Novel ultra-deformable vesicles entrapped with bleomycin and enhanced to penetrate rat skin
    • DOI 10.1016/j.jconrel.2006.04.016, PII S0168365906001945
    • Hiruta Y, Hattori Y, Kawano K, et al. (2006). Novel ultra-deformable vesicles entrapped with bleomycin and enhanced to penetrate rat skin. J Control Release 113:146-54. (Pubitemid 43928150)
    • (2006) Journal of Controlled Release , vol.113 , Issue.2 , pp. 146-154
    • Hiruta, Y.1    Hattori, Y.2    Kawano, K.3    Obata, Y.4    Maitani, Y.5
  • 35
    • 0029061075 scopus 로고
    • Interactions between liposomes and human stratum corneum in vitro: Freeze fracture electron microscopical visualization and small angle X-ray scattering studies
    • Hofland HE, Bouwstra JA, Bodde HE, et al. (1995). Interactions between liposomes and human stratum corneum in vitro: freeze fracture electron microscopical visualization and small angle X-ray scattering studies. Br J Dermatol 132:853-66.
    • (1995) Br J Dermatol , vol.132 , pp. 853-866
    • Hofland, H.E.1    Bouwstra, J.A.2    Bodde, H.E.3
  • 36
    • 21744457427 scopus 로고    scopus 로고
    • Vesicles as a tool for transdermal and dermal delivery
    • DOI 10.1016/j.ddtec.2005.05.003, PII S1740674905000089
    • Honeywell-Nguyen PL, Bouwstra J. (2005). Vesicles as a tool for transdermal and dermal delivery. Drug Discov Today Technol 2: 67-74. (Pubitemid 40946310)
    • (2005) Drug Discovery Today: Technologies , vol.2 , Issue.1 , pp. 67-74
    • Honeywell-Nguyen, P.L.1    Bouwstra, J.A.2
  • 37
    • 0028272947 scopus 로고
    • Forum in ''Liposomes in Controlled Release''
    • Huang L. (1994). Forum in ''Liposomes in Controlled Release''. J Liposome Res 4:327-30.
    • (1994) J Liposome Res , vol.4 , pp. 327-330
    • Huang, L.1
  • 38
    • 0015241658 scopus 로고
    • Molecular motion in spin-labeled phospholipids and membranes
    • Hubbel WL, McConnel HM. (1971). Molecular motion in spin-labeled phospholipids and membranes. J Am Chem Soc 93:314-26.
    • (1971) J Am Chem Soc , vol.93 , pp. 314-326
    • Hubbel, W.L.1    McConnel, H.M.2
  • 39
    • 0014822895 scopus 로고
    • Spin-labeled Neurospora mitochondria
    • Keith AD, Bulfield G, Snipes W. (1970). Spin-labeled Neurospora mitochondria. Biophys J 10:618-26.
    • (1970) Biophys J , vol.10 , pp. 618-626
    • Keith, A.D.1    Bulfield, G.2    Snipes, W.3
  • 40
    • 0142165039 scopus 로고    scopus 로고
    • In vitro and in vivo transfection efficiency of a novel ultradeformable cationic liposome
    • DOI 10.1016/S0142-9612(03)00534-9
    • Kim A, Lee EH, Choi SH, Kim CK. (2004). In vitro and in vivo transfection efficiency of a novel ultradeformable cationic liposome. Biomaterials 25:305-13. (Pubitemid 37329720)
    • (2004) Biomaterials , vol.25 , Issue.2 , pp. 305-313
    • Kim, A.1    Lee, E.H.2    Choi, S.-H.3    Kim, C.-K.4
  • 41
    • 0022424856 scopus 로고
    • Preparation of multilamellar vesicles of defined size-distribution by solvent-spherule evaporation
    • Kim S, Jacobs RE, White SH. (1985). Preparation of multilamellar vesicles of defined size-distribution by solvent-spherule evaporation. Biochim Biophys Acta 812:793-801.
    • (1985) Biochim Biophys Acta , vol.812 , pp. 793-801
    • Kim, S.1    Jacobs, R.E.2    White, S.H.3
  • 42
    • 0021098343 scopus 로고
    • Preparation of multivesicular liposomes
    • Kim S, Turker MS, Chi EY, et al. (1983). Preparation of multivesicular liposomes. Biochim Biophys Acta 728:339-48.
    • (1983) Biochim Biophys Acta , vol.728 , pp. 339-348
    • Kim, S.1    Turker, M.S.2    Chi, E.Y.3
  • 44
    • 0025308099 scopus 로고
    • Controlled drug release from a novel liposomal delivery system. II. Transdermal delivery characteristics
    • Knepp VM, Szoka FC, Guy RH. (1990). Controlled drug release from a novel liposomal delivery system. II. Transdermal delivery characteristics. J Control Release 12:25-30. (Pubitemid 20101608)
    • (1990) Journal of Controlled Release , vol.12 , Issue.1 , pp. 25-30
    • Knepp, V.M.1    Szoka Jr., F.C.2    Guy, R.H.3
  • 45
    • 0024289274 scopus 로고
    • The mechanism of vesicle formation
    • Lasic DD. (1988). The mechanism of vesicle formation. Biochem J 256: 1-11.
    • (1988) Biochem J , vol.256 , pp. 1-11
    • Lasic, D.D.1
  • 46
    • 0028886643 scopus 로고
    • Transmembrane gradient driven phase transitions within vesicles: Lessons for drug delivery
    • Lasic DD, Ceh B, Stuart MC, et al. (1995). Transmembrane gradient driven phase transitions within vesicles: lessons for drug delivery. Biochim Biophys Acta 1239:145-56.
    • (1995) Biochim Biophys Acta , vol.1239 , pp. 145-156
    • Lasic, D.D.1    Ceh, B.2    Stuart, M.C.3
  • 47
    • 0028306506 scopus 로고
    • Preparation and characterization of liposome-encapsulated haemoglobin by a freeze-thaw method
    • Liu L, Yonetaini T. (1994). Preparation and characterization of liposome-encapsulated haemoglobin by a freeze-thaw method. J Microencapsulation 11:409-21. (Pubitemid 24209455)
    • (1994) Journal of Microencapsulation , vol.11 , Issue.4 , pp. 409-421
    • Liu, L.1    Yonetani, T.2
  • 50
    • 0019309326 scopus 로고
    • Liposomes - A selective drug delivery system for the topical route of administration. I. Lotion dosage form
    • DOI 10.1016/0024-3205(80)90268-4
    • Mezei M, Gulasekharam V. (1980). Liposomes-a selective drug delivery system for the topical route of administration: lotion dosage form. Life Sci 26:1473-7. (Pubitemid 10042852)
    • (1980) Life Sciences , vol.26 , Issue.18 , pp. 1473-1477
    • Mezei, M.1    Gulasekharam, V.2
  • 51
    • 0019958118 scopus 로고
    • Liposomes. A selective drug delivery system for the topical route of administration: Gel dosage form
    • Mezei M, Gulasekharam V. (1982). Liposomes-a selective drug delivery system for the topical route of administration: gel dosage form. J Pharm Pharmacol 34:473-4. (Pubitemid 12082555)
    • (1982) Journal of Pharmacy and Pharmacology , vol.34 , Issue.7 , pp. 473-474
    • Mezei, M.1    Gulasekharam, V.2
  • 52
    • 33646843784 scopus 로고    scopus 로고
    • Elastic liposomes mediated transcutaneous immunization against Hepatitis B
    • DOI 10.1016/j.vaccine.2006.03.011, PII S0264410X06002763
    • Mishra D, Dubey V, Asthana A, et al. (2006). Elastic liposomes mediated transcutaneous immunization against Hepatitis B. Vaccine 24: 4847-55. (Pubitemid 43776800)
    • (2006) Vaccine , vol.24 , Issue.22 , pp. 4847-4855
    • Mishra, D.1    Dubey, V.2    Asthana, A.3    Saraf, D.K.4    Jain, N.K.5
  • 54
    • 0025823988 scopus 로고
    • Preparation and characterization of polymer coated small unilamellar vesicles
    • Oezden MY, Hasirci VN. (1991). Preparation and characterization of polymer coated small unilamellar vesicles. Biochim Biophys Acta 1075:102-8.
    • (1991) Biochim Biophys Acta , vol.1075 , pp. 102-108
    • Oezden, M.Y.1    Hasirci, V.N.2
  • 55
    • 0030050088 scopus 로고    scopus 로고
    • Mechanism for enhancement effect of lipid disperse system on percutaneous absorption
    • DOI 10.1021/js950178x
    • Ogiso T, Niinaka N, Iwaki M. (1996). Mechanism for enhancement effect of lipid disperse system on percutaneous absorption. J Pharm Sci 85: 57-64. (Pubitemid 26029626)
    • (1996) Journal of Pharmaceutical Sciences , vol.85 , Issue.1 , pp. 57-64
    • Ogiso, T.1    Niinaka, N.2    Iwaki, M.3
  • 56
    • 84866999771 scopus 로고    scopus 로고
    • Structural analysis of ''flexible'' liposome formulations: New insights into the skin-penetrating ability of soft nanostructures
    • Ogunsola OA, Margaret E, Kraeling B, et al. (2012). Structural analysis of ''flexible'' liposome formulations: new insights into the skin-penetrating ability of soft nanostructures. Soft Mater 8:10226-32.
    • (2012) Soft Mater , vol.8 , pp. 10226-10232
    • Ogunsola, O.A.1    Margaret, E.2    Kraeling, B.3
  • 58
    • 0022407290 scopus 로고
    • Studies on the effect of water-soluble additives and on the encapsulation mechanism in liposome preparation by the freeze-thawing method
    • Ohsawa T, Miura H, Harada K. (1985). Studies on the effect of water-soluble additives and on the encapsulation mechanism in liposome preparation by the freeze-thawing method. Chem Pharm Bull 33: 5474-83. (Pubitemid 16184038)
    • (1985) Chemical and Pharmaceutical Bulletin , vol.33 , Issue.12 , pp. 5474-5483
    • Ohsawa, T.1    Miura, H.2    Harada, K.3
  • 59
    • 0021112303 scopus 로고
    • Solubilization of phospholipids by chaotropic ion solutions
    • Oku N, MacDonald RC. (1983). Solubilization of phospholipids by chaotropic ion solutions. J Biol Chem 258:8733-8.
    • (1983) J Biol Chem , vol.258 , pp. 8733-8738
    • Oku, N.1    MacDonald, R.C.2
  • 63
    • 0019642980 scopus 로고
    • Liposomes with a large trapping capacity prepared by freezing and thawing of sonicated phospholipid mixtures
    • Pick U. (1981). Liposomes with a large trapping capacity prepared by freezing and thawing of sonicated phospholipid mixtures. Arch Biochem Biophys 212:186-94.
    • (1981) Arch Biochem Biophys , vol.212 , pp. 186-194
    • Pick, U.1
  • 64
    • 0022559222 scopus 로고
    • Mimicry and mechanism in phospholipid models of membrane fusion
    • Rand RP, Parsegiam VA. (1986). Mimicry and mechanism in phospho-lipid models of membrane fusion. Ann Rev Physiol 48:201-12. (Pubitemid 16047609)
    • (1986) Annual Review of Physiology , vol.VOL. 48 , pp. 201-212
    • Rand, R.P.1    Parsegian, V.A.2
  • 65
    • 84864472190 scopus 로고    scopus 로고
    • Liposomes preparation methods
    • Riaz M. (1996). Liposomes preparation methods. Pak J Pharm Sci 19: 65-77.
    • (1996) Pak J Pharm Sci , vol.19 , pp. 65-77
    • Riaz, M.1
  • 66
    • 84964994274 scopus 로고
    • Stability and uses of liposomes
    • Riaz M. (1995). Stability and uses of liposomes. Pak J Pharm Sci 8: 69-79.
    • (1995) Pak J Pharm Sci , vol.8 , pp. 69-79
    • Riaz, M.1
  • 67
    • 84858341355 scopus 로고
    • Stability of phosphoinosityles containing liposomes: Effects of triton x-100, temperature and 68 rpm
    • Riaz M, Weiner N. (1994). Stability of phosphoinosityles containing liposomes: effects of triton x-100, temperature and 68 rpm. Pak J Pharm Sci 7:61-8.
    • (1994) Pak J Pharm Sci , vol.7 , pp. 61-68
    • Riaz, M.1    Weiner, N.2
  • 69
    • 0031898536 scopus 로고    scopus 로고
    • Non-uniform cellular packing of the stratum corneum and permeability barrier function of intact skin: A high-resolution confocal laser scanning microscopy study using highly deformable vesicles (Transfersomes)
    • DOI 10.1046/j.1365-2133.1998.02166.x
    • Schatzlein A, Cevc G. (1998). Non-uniform cellular packing of the stratum corneum and permeability barrier function of intact skin: a high resolution confocal laser scanning microscopy study using highly deformable vesicles (transfersomes). Br J Dermatol 138:583-92. (Pubitemid 28212240)
    • (1998) British Journal of Dermatology , vol.138 , Issue.4 , pp. 583-592
    • Schatzlein, A.1    Cevc, G.2
  • 70
    • 0017819910 scopus 로고
    • Comparison of large unilamellar vesicles prepared by a petroleum ether vaporization method with multilamellar vesicles. ESR, diffusion and entrapment analyses
    • Schieren H, Rudolph S, Findelstein M, et al. (1978). Comparison of large unilamellar vesicles prepared by a petroleum ether vaporization method with multilamellar vesicles: ESR, diffusion and entrapment analyses. Biochim Biophys Acta 542:137-53. (Pubitemid 8394755)
    • (1978) Biochimica et Biophysica Acta , vol.542 , Issue.1 , pp. 137-153
    • Schieren, H.1    Rudolph, S.2    Finkelstein, M.3
  • 71
    • 0028334473 scopus 로고
    • Liposomes and niosomes as topical drug carriers: Dermal and transdermal drug delivery
    • DOI 10.1016/0168-3659(94)90039-6
    • Schreier H, Bouwstra J. (1994). Liposomes and niosomes as topical drug carriers-dermal and transdermal drug-delivery. J Control Release 30: 1-15. (Pubitemid 24173173)
    • (1994) Journal of Controlled Release , vol.30 , Issue.1 , pp. 1-15
    • Schreier, H.1
  • 72
    • 0000877398 scopus 로고
    • Spin label studies for oriented smectic crystals: A model system for bilayer membranes
    • Seelig J. (1970). Spin label studies for oriented smectic crystals: a model system for bilayer membranes. J Am Chem Soc 92:3881-7.
    • (1970) J Am Chem Soc , vol.92 , pp. 3881-3887
    • Seelig, J.1
  • 73
    • 24644443167 scopus 로고    scopus 로고
    • Topical delivery of low-molecular-weight heparin with surface-charged flexible liposomes
    • Song YK, Kim CK. (2006). Topical delivery of low-molecular-weight heparin with surface-charged flexible liposomes. Biomaterials 27: 271-80.
    • (2006) Biomaterials , vol.27 , pp. 271-280
    • Song, Y.K.1    Kim, C.K.2
  • 75
    • 0027131935 scopus 로고
    • Amphotericin B formulated in liposomes and lipid based systems: A review
    • Szoka FC, Tang M. (1993). Amphotericin B formulated in liposomes and lipid based systems: a review. J Liposome Res 3:363-75. (Pubitemid 24007406)
    • (1993) Journal of Liposome Research , vol.3 , Issue.3 , pp. 363-375
    • Szoka Jr., F.C.1    Tang, M.2
  • 76
    • 0033996247 scopus 로고    scopus 로고
    • Ethosomes - Novel vesicular carriers for enhanced delivery: Characterization and skin penetration properties
    • DOI 10.1016/S0168-3659(99)00222-9, PII S0168365999002229
    • Touitou E, Dayan N, Bergelson L, et al. (2000a). Ethosomes-novel vesicular carriers for enhanced delivery: characterization and skin penetration properties. J Control Release 65:403-18. (Pubitemid 30122942)
    • (2000) Journal of Controlled Release , vol.65 , Issue.3 , pp. 403-418
    • Touitou, E.1    Dayan, N.2    Bergelson, L.3    Godin, B.4    Eliaz, M.5
  • 77
    • 0035889823 scopus 로고    scopus 로고
    • Intracellular delivery mediated by ethosomal carrier
    • Touitou E, Godin B, Dayan N. (2001). Intracellular delivery mediated by ethosomal carrier. Biomaterials 22:3055-9.
    • (2001) Biomaterials , vol.22 , pp. 3055-3059
    • Touitou, E.1    Godin, B.2    Dayan, N.3
  • 78
    • 0033819278 scopus 로고    scopus 로고
    • Enhanced delivery of drugs into and across the skin by ethosomal carriers
    • Touitou E, Godin B, Weiss C. (2000b). Enhanced delivery of drugs into and across the skin by ethosomal carriers. Drug Dev Res 50:406-15.
    • (2000) Drug Dev Res , vol.50 , pp. 406-415
    • Touitou, E.1    Godin, B.2    Weiss, C.3
  • 79
    • 0037173516 scopus 로고    scopus 로고
    • Elastic liposomes for skin delivery of dipotassium glycyrrhizinate
    • DOI 10.1016/S0378-5173(02)00266-1, PII S0378517302002661
    • Trotta M, Peira E, Debernardi F, Gallarate M. (2002). Elastic liposomes for skin delivery of dipotassium glycyrrhizinate. Int J Pharm 241: 319-27. (Pubitemid 34718033)
    • (2002) International Journal of Pharmaceutics , vol.241 , Issue.2 , pp. 319-327
    • Trotta, M.1    Peira, E.2    Debernardi, F.3    Gallarate, M.4
  • 82
    • 0032848216 scopus 로고    scopus 로고
    • Elasticity of vesicles affects hairless mouse skin structure and permeability
    • DOI 10.1016/S0168-3659(99)00168-6, PII S0168365999001686
    • van den Bergh BA, Bouwstra JA, Junginger HE, Wertz PW. (1999a). Elasticity of vesicles affects hairless mouse skin structure and permeability. J Control Release 62:367-79. (Pubitemid 29476584)
    • (1999) Journal of Controlled Release , vol.62 , Issue.3 , pp. 367-379
    • Van Den Bergh, B.A.I.1    Bouwstra, J.A.2    Junginger, H.E.3    Wertz, P.W.4
  • 83
    • 0033380418 scopus 로고    scopus 로고
    • Interactions of elastic and rigid vesicles with human skin in vitro: Electron microscopy and two-photon excitation microscopy
    • DOI 10.1016/S0005-2736(99)00176-5, PII S0005273699001765
    • van den Bergh BA, Vroom J, Gerritsen H, et al. (1999b). Interactions of elastic and rigid vesicles with human skin in vitro: electron microscopy and two-photon excitation microscopy. Biochim Biophys Acta 1461:155-73. (Pubitemid 30077471)
    • (1999) Biochimica et Biophysica Acta - Biomembranes , vol.1461 , Issue.1 , pp. 155-173
    • Van Den Bergh, B.A.I.1    Vroom, J.2    Gerritsen, H.3    Junginger, H.E.4    Bouwstra, J.A.5
  • 84
    • 0032557221 scopus 로고    scopus 로고
    • Interactions between liposomes and human skin in vitro, a confocal laser scanning microscopy study
    • DOI 10.1016/S0005-2736(97)00273-3, PII S0005273697002733
    • van Kuijk-Meuwissen ME, Junginger HE, Bouwstra JA. (1998). Interactions between liposomes and human skin in vitro, a confocal laser scanning microscopy study. Biochim Biophys Acta 1371:31-9. (Pubitemid 28197051)
    • (1998) Biochimica et Biophysica Acta - Biomembranes , vol.1371 , Issue.1 , pp. 31-39
    • Van Kuijk-Meuwissen, M.E.M.J.1    Junginger, H.E.2    Bouwstra, J.A.3
  • 85
    • 0038061619 scopus 로고    scopus 로고
    • Liposomes increase skin penetration of entrapped and non-entrapped hydrophilic substances into human skin: A skin penetration and confocal laser scanning microscopy study
    • DOI 10.1016/S0939-6411(03)00021-3
    • Verma DD, Verma S, Blume G, Fahr A. (2003). Liposomes increase skin penetration of entrapped and non-entrapped hydrophilic substances into human skin: a skin penetration and confocal laser scanning microscopy study. Eur J Pharm Biopharm 55:271-7. (Pubitemid 36561553)
    • (2003) European Journal of Pharmaceutics and Biopharmaceutics , vol.55 , Issue.3 , pp. 271-277
    • Verma, D.D.1    Verma, S.2    Blume, G.3    Fahr, A.4
  • 86
    • 0021276753 scopus 로고
    • Liposomes as drug carriers in cancer chemotherapy
    • Weinatein JN, Lenetman LD. (1984). Liposomes as drug carriers in cancer chemotherapy. Pharmacol Ther 24:207-33.
    • (1984) Pharmacol Ther , vol.24 , pp. 207-233
    • Weinatein, J.N.1    Lenetman, L.D.2
  • 88
    • 0029128104 scopus 로고
    • Interaction of phosphatidylcholine liposomes with the human stratum corneum
    • Zellmer S, Pfeil W, Lasch J. (1995). Interaction of phosphatidylcholine liposomes with the human stratum corneum. Biochim Biophys Acta 1237:176-82.
    • (1995) Biochim Biophys Acta , vol.1237 , pp. 176-182
    • Zellmer, S.1    Pfeil, W.2    Lasch, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.