Synthesis, antitubercular and anticancer activity of new Baylis-Hillman adduct-derived N-cinnamyl-substituted isatin derivatives

Medicinal Chemistry Research

Volumn 23, Issue 4, 2014, Pages 1934-1940

  Kumar, Sriramoju Bharath ^a   Ravinder, Mettu ^a   Kishore, Golla ^b   Jayathirtha Rao, Vaidya ^a   Yogeeswari, Perumal ^c   Sriram, Darmarajan ^c  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

^b UNIVERSITY OF HYDERABAD   (India)

^c BIRLA INSTITUTE OF TECHNOLOGY AND SCIENCE   (India)

Author keywords

Antitumor agents; Baylis Hillman bromides; Cytotoxicity; Isatins

Indexed keywords

CYTOTOXIC AGENT; ETHAMBUTOL; ISATIN DERIVATIVE; ISONIAZID; METHYL 2 [(2,3 DIOXO 2,3 DIHYDRO 1H 1 INDOLYL)METHYL]3 PHENYL 2 PROPIONATE; METHYL 2 [(5 BROMO 2,3 DIOXO 2,3 DIHYDRO 1H 1 INDOLYL)METHYL]3 PHENYL 2 PROPIONATE; METHYL 2 [(5 CHLORO 2,3 DIOXO 2,3 DIHYDRO 1H 1 INDOLYL)METHYL]3 PHENYL 2 PROPIONATE; METHYL 2 [(5 FLUORO 2,3 DIOXO 2,3 DIHYDRO 1H 1 INDOLYL)METHYL]3 PHENYL 2 PROPIONATE; METHYL 3 (4 BROMOPHENYL) 2 [(2,3 DIOXO 2,3 DIHYDRO 1H 1 INDOLYL)METHYL] 2 PROPIONATE; METHYL 3 (4 BROMOPHENYL) 2 [(5 BROMO 2,3 DIOXO 2,3 DIHYDRO 1H 1 INDOLYL)METHYL] 2 PROPIONATE; METHYL 3 (4 BROMOPHENYL) 2 [(5 CHLORO 2,3 DIOXO 2,3 DIHYDRO 1H 1 INDOLYL)METHYL] 2 PROPIONATE; METHYL 3 (4 BROMOPHENYL) 2 [(5 FLUORO 2,3 DIOXO 2,3 DIHYDRO 1H 1 INDOLYL)METHYL] 2 PROPIONATE; METHYL 3 (4 NITROPHENYL) 2 [(2,3 DIOXO 2,3 DIHYDRO 1H 1 INDOLYL)METHYL] 2 PROPIONATE; METHYL 3 (4 NITROPHENYL) 2 [(5 BROMO 2,3 DIOXO 2,3 DIHYDRO 1H 1 INDOLYL)METHYL] 2 PROPIONATE; METHYL 3 (4 NITROPHENYL) 2 [(5 CHLORO 2,3 DIOXO 2,3 DIHYDRO 1H 1 INDOLYL)METHYL] 2 PROPIONATE; METHYL 3 (4 NITROPHENYL) 2 [(5 FLUORO 2,3 DIOXO 2,3 DIHYDRO 1H 1 INDOLYL)METHYL] 2 PROPIONATE; PYRAZINAMIDE; RIFAMPICIN; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; BAYLIS HILLMAN REACTION; CANCER CELL; CELL VIABILITY; CHO CELL; COLON CANCER; CONTROLLED STUDY; CYTOTOXICITY; DRUG SCREENING; DRUG SYNTHESIS; GLIOMA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; LYMPHOMA CELL; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN;

EID: 84898963071     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-013-0787-x     Document Type: Article

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