메뉴 건너뛰기




Volumn 29, Issue 4, 2014, Pages 683-696

Antimicrobial host defence peptide, LL-37, as a potential vaginal contraceptive

(20)  Srakaew, Nopparat a   Young, Charlene D a   Sae Wu, Arpornrad a   Xu, Hongbin a,b   Quesnel, Krista L a,b   Di Brisco, Riccardo a   Kongmanas, Kessiri a,b   Fongmoon, Duriya a   Hommalai, Greanggrai a   Weerachatyanukul, Wattana c   Hall, Susan H d   Zhang, Yong Lian e   Panza, Luigi f   Franchini, Laura g   Compostella, Federica g   Pearson, Terry W h   Hancock, Robert E i   Oko, Richard J j   Hermo, Louis S k   Tanphaichitr, Nongnuj a,b  


Author keywords

LL 37; Sperm fertilizing ability; Sperm plasma membrane; Vaginal contraceptive

Indexed keywords

CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; ANTIMICROBIAL CATIONIC PEPTIDE; CAP18 LIPOPOLYSACCHARIDE-BINDING PROTEIN; CONTRACEPTIVE AGENT;

EID: 84898944079     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/deu018     Document Type: Article
Times cited : (30)

References (46)
  • 1
    • 1642281205 scopus 로고    scopus 로고
    • Contraceptive efficacy of antimicrobial peptide Nisin: In vitro and in vivo studies
    • DOI 10.1016/j.contraception.2003.11.002, PII S0010782403002981
    • Aranha C, Gupta S, Reddy KV. Contraceptive efficacy of antimicrobial peptide Nisin: In vitro and in vivo studies. Contraception 2004;69:333-338. (Pubitemid 38366466)
    • (2004) Contraception , vol.69 , Issue.4 , pp. 333-338
    • Aranha, C.1    Gupta, S.2    Reddy, K.V.R.3
  • 5
    • 15844363885 scopus 로고    scopus 로고
    • Role of actin cytoskeleton in mammalian sperm capacitation and the acrosome reaction
    • DOI 10.1530/rep.1.00269
    • Breitbart H, Cohen G, Rubinstein S. Role of actin cytoskeleton in mammalian sperm capacitation and the acrosome reaction. Reproduction 2005; 129:263-268. (Pubitemid 40425636)
    • (2005) Reproduction , vol.129 , Issue.3 , pp. 263-268
    • Breitbart, H.1    Cohen, G.2    Rubinstein, S.3
  • 6
    • 14544282377 scopus 로고    scopus 로고
    • Antimicrobial peptides: Pore formers or metabolic inhibitors in bacteria?
    • Brogden KA. Antimicrobial peptides: Pore formers or metabolic inhibitors in bacteria? Nat Rev Microbiol 2005;3:238-250.
    • (2005) Nat Rev Microbiol , vol.3 , pp. 238-250
    • Brogden, K.A.1
  • 7
    • 34147139491 scopus 로고    scopus 로고
    • Release of the antimicrobial peptide LL-37 from DNA/F-actin bundles in cystic fibrosis sputum
    • DOI 10.1183/09031936.00080806
    • Bucki R, Byfield FJ, Janmey PA. Release of the antimicrobial peptide LL-37 from DNA/F-actin bundles in cystic fibrosis sputum. Eur Respir J 2007; 29:624-632. (Pubitemid 46554610)
    • (2007) European Respiratory Journal , vol.29 , Issue.4 , pp. 624-632
    • Bucki, R.1    Byfield, F.J.2    Janmey, P.A.3
  • 10
    • 1042290511 scopus 로고    scopus 로고
    • Susceptibility of Treponema pallidum to host-derived antimicrobial peptides
    • DOI 10.1016/j.peptides.2003.07.026
    • Cox DL, Sun Y, Liu H, Lehrer RI, Shafer WM. Susceptibility of Treponema pallidum to host-derived antimicrobial peptides. Peptides 2003; 24:1741-1746. (Pubitemid 38198080)
    • (2003) Peptides , vol.24 , Issue.11 , pp. 1741-1746
    • Cox, D.L.1    Sun, Y.2    Liu, H.3    Lehrer, R.I.4    Shafer, W.M.5
  • 11
    • 20544447535 scopus 로고    scopus 로고
    • Candidacidal effects of two antimicrobial peptides: Histatin 5 causes small membrane defects, but LL-37 causes massive disruption of the cell membrane
    • Den Hertog AL, van Marle J, van Veen HA, Van't Hof W, Bolscher JG, Veerman EC, Nieuw Amerongen AV. Candidacidal effects of two antimicrobial peptides: Histatin 5 causes small membrane defects, but LL-37 causes massive disruption of the cell membrane. Biochem J 2005; 388:689-695.
    • (2005) Biochem J , vol.388 , pp. 689-695
    • Den Hertog, A.L.1    Van Marle, J.2    Van Veen, H.A.3    Van'T Hof, W.4    Bolscher, J.G.5    Veerman, E.C.6    Nieuw Amerongen, A.V.7
  • 14
    • 14044261253 scopus 로고    scopus 로고
    • Percoll gradient-centrifuged capacitated mouse sperm have increased fertilizing ability and higher contents of sulfogalactosylglycerolipid and docosahexaenoic acid-containing phosphatidylcholine compared to washed capacitated mouse sperm
    • DOI 10.1095/biolreprod.104.036095
    • Furimsky A, Vuong N, Xu H, Kumarathasan P, Xu M, WeerachatyanukulW, Bou Khalil M, Kates M, Tanphaichitr N. Percoll gradient-centrifuged capacitated mouse sperm have increased fertilizing ability and higher contents of sulfogalactosylglycerolipid and docosahexaenoic acidcontaining phosphatidylcholine compared to washed capacitated mouse sperm. Biol Reprod 2005;72:574-583. (Pubitemid 40279835)
    • (2005) Biology of Reproduction , vol.72 , Issue.3 , pp. 574-583
    • Furimsky, A.1    Vuong, N.2    Xu, H.3    Kumarathasan, P.4    Xu, M.5    Weerachatyanukul, W.6    Khalil, M.B.7    Kates, M.8    Tanphaichitr, N.9
  • 15
  • 17
    • 0021336185 scopus 로고
    • Development of an assay to assess the functional integrity of the human sperm membrane and its relationship to other semen characteristics
    • Jeyendran RS, Van Der Ven HH, Perez-Pelaez M, Crabo BG, Zaneveld LJ. Development of an assay to assess the functional integrity of the human sperm membrane and its relationship to other semen characteristics. J Reprod Fert 1984;70:219-228. (Pubitemid 14223140)
    • (1984) Journal of Reproduction and Fertility , vol.70 , Issue.1 , pp. 219-228
    • Jeyendran, R.S.1    Van Der Ven, H.H.2    Perez Pelaez, M.3
  • 18
    • 11144348648 scopus 로고    scopus 로고
    • Interaction and cellular localization of the human host defense peptide LL-37 with lung epithelial cells
    • DOI 10.1128/IAI.73.1.583-591.2005
    • Lau YE, Rozek A, Scott MG, Goosney DL, Davidson DJ, Hancock RE. Interaction and cellular localization of the human host defense peptide LL-37 with lung epithelial cells. Infect Immun 2005;73:583-591. (Pubitemid 40041153)
    • (2005) Infection and Immunity , vol.73 , Issue.1 , pp. 583-591
    • Lau, Y.E.1    Rozek, A.2    Scott, M.G.3    Goosney, D.L.4    Davidson, D.J.5    Hancock, R.E.W.6
  • 19
    • 0033918174 scopus 로고    scopus 로고
    • The human cationic antimicrobial protein (hCAP-18) is expressed in the epithelium of human epididymis, is present in seminal plasma at high concentrations, and is attached to spermatozoa
    • DOI 10.1128/IAI.68.7.4297-4302.2000
    • Malm J, Sorensen O, Persson T, Frohm-Nilsson M, Johansson B, Bjartell A, Lilja H, Stahle-Backdahl M, Borregaard N, Egesten A. The human cationic antimicrobial protein (hCAP-18) is expressed in the epithelium of human epididymis, is present in seminal plasma at high concentrations, and is attached to spermatozoa. Infect Immun 2000;68:4297-4302. (Pubitemid 30434586)
    • (2000) Infection and Immunity , vol.68 , Issue.7 , pp. 4297-4302
    • Malm, J.1    Sorensen, O.2    Persson, T.3    Frohm-Nilsson, M.4    Johansson, B.5    Bjartell, A.6    Lilja, H.7    Stahle-Backdahl, M.8    Borregaard, N.9    Egesten, A.10
  • 20
    • 84868280171 scopus 로고    scopus 로고
    • Performing vaginal lavage, crystal violet staining, and vaginal cytological evaluation for mouse estrous cycle staging identification
    • McLean AC, Valenzuela N, Fai S, Bennett SA. Performing vaginal lavage, crystal violet staining, and vaginal cytological evaluation for mouse estrous cycle staging identification. J Vis Exp 2012;67:e4389.
    • (2012) J Vis Exp , vol.67
    • McLean, A.C.1    Valenzuela, N.2    Fai, S.3    Bennett, S.A.4
  • 22
    • 77951092674 scopus 로고    scopus 로고
    • Kallikrein expression and cathelicidin processing are independently controlled in keratinocytes by calcium, vitamin D(3), and retinoic acid
    • Morizane S, Yamasaki K, Kabigting FD, Gallo RL. Kallikrein expression and cathelicidin processing are independently controlled in keratinocytes by calcium, vitamin D(3), and retinoic acid. J Invest Dermatol 2010; 130:1297-1306.
    • (2010) J Invest Dermatol , vol.130 , pp. 1297-1306
    • Morizane, S.1    Yamasaki, K.2    Kabigting, F.D.3    Gallo, R.L.4
  • 24
    • 58149263244 scopus 로고    scopus 로고
    • The roles of cathelicidin LL-37 in immune defences and novel clinical applications
    • Nijnik A, Hancock RE. The roles of cathelicidin LL-37 in immune defences and novel clinical applications. Curr Opin Hematol 2009;16:41-47.
    • (2009) Curr Opin Hematol , vol.16 , pp. 41-47
    • Nijnik, A.1    Hancock, R.E.2
  • 26
    • 84860601877 scopus 로고    scopus 로고
    • Antimicrobial peptides: Key components of the innate immune system
    • Pasupuleti M, Schmidtchen A, Malmsten M. Antimicrobial peptides: Key components of the innate immune system. Crit Rev Biotech 2012; 32:143-171.
    • (2012) Crit Rev Biotech , vol.32 , pp. 143-171
    • Pasupuleti, M.1    Schmidtchen, A.2    Malmsten, M.3
  • 28
    • 0029871082 scopus 로고    scopus 로고
    • Spermicidal activity of magainins: In vitro and in vivo studies
    • DOI 10.1016/0010-7824(96)00038-8
    • Reddy KV, Shahani SK, Meherji PK. Spermicidal activity of Magainins: In vitro and in vivo studies. Contraception 1996;53:205-210. (Pubitemid 26118148)
    • (1996) Contraception , vol.53 , Issue.4 , pp. 205-210
    • Reddy, K.V.R.1    Shahani, S.K.2    Meherji, P.K.3
  • 29
    • 34248679167 scopus 로고    scopus 로고
    • Tricine-Sds-Page
    • Schagger H. Tricine-SDS-PAGE. Nat Protoc 2006;1:16-22.
    • (2006) Nat Protoc , vol.1 , pp. 16-22
    • Schagger, H.1
  • 30
    • 0033937030 scopus 로고    scopus 로고
    • Activity of cecropin P1 and FA-LL-37 against urogenital microflora
    • DOI 10.1016/S1286-4579(00)90359-9
    • Smeianov V, Scott K, Reid G. Activity of cecropin P1 and FA-LL-37 against urogenital microflora. Microbes Infect 2000;2:773-777. (Pubitemid 30451218)
    • (2000) Microbes and Infection , vol.2 , Issue.7 , pp. 773-777
    • Smeianov, V.1    Scott, K.2    Reid, G.3
  • 32
    • 0035877995 scopus 로고    scopus 로고
    • Human cathelicidin, hCAP-18, is processed to the antimicrobial peptide LL-37 by extracellular cleavage with proteinase 3
    • Sorensen OE, Follin P, Johnsen AH, Calafat J, Tjabringa GS, Hiemstra PS, Borregaard N. Human cathelicidin, hCAP-18, is processed to the antimicrobial peptide LL-37 by extracellular cleavage with proteinase 3. Blood 2001;97:3951-3959.
    • (2001) Blood , vol.97 , pp. 3951-3959
    • Sorensen, O.E.1    Follin, P.2    Johnsen, A.H.3    Calafat, J.4    Tjabringa, G.S.5    Hiemstra, P.S.6    Borregaard, N.7
  • 35
    • 0023875268 scopus 로고
    • Egg-penetration ability and structural properties of human sperm prepared by Percoll-gradient centrifugation
    • Tanphaichitr N, Millette CF, Agulnick A, Fitzgerald LM. Egg-penetration ability and structural properties of human sperm prepared by Percoll-gradient centrifugation. Gamete Res 1988;20:67-81.
    • (1988) Gamete Res , vol.20 , pp. 67-81
    • Tanphaichitr, N.1    Millette, C.F.2    Agulnick, A.3    Fitzgerald, L.M.4
  • 38
    • 0021154990 scopus 로고
    • Immunoblotting and dot immunobinding. Current status and outlook
    • Towbin H, Gordon J. Immunoblotting and dot immunobinding-current status and outlook. J Immunol Methods 1984;72:313-340. (Pubitemid 14062873)
    • (1984) Journal of Immunological Methods , vol.72 , Issue.2 , pp. 313-340
    • Towbin, H.1    Gordon, J.2
  • 40
    • 0033570112 scopus 로고    scopus 로고
    • Cholesterol efflux-mediated signal transduction in mammalian sperm: Cholesterol release signals an increase in protein tyrosine phosphorylation during mouse sperm capacitation
    • DOI 10.1006/dbio.1999.9428
    • Visconti PE, Ning X, Fornes MW, Alvarez JG, Stein P, Connors SA, Kopf GS. Cholesterol efflux-mediated signal transduction in mammalian sperm: Cholesterol release signals an increase in protein tyrosine phosphorylation during mouse sperm capacitation. Dev Biol 1999;214:429-443. (Pubitemid 29483103)
    • (1999) Developmental Biology , vol.214 , Issue.2 , pp. 429-443
    • Visconti, P.E.1    Ning, X.2    Fornes, M.W.3    Alvarez, J.G.4    Stein, P.5    Connors, S.A.6    Kopf, G.S.7
  • 41
    • 57749088664 scopus 로고    scopus 로고
    • Structures of human host defense cathelicidin LL-37 and its smallest antimicrobial peptide KR-12 in lipid micelles
    • Wang G. Structures of human host defense cathelicidin LL-37 and its smallest antimicrobial peptide KR-12 in lipid micelles. J Biol Chem 2008; 283:32637-32643.
    • (2008) J Biol Chem , vol.283 , pp. 32637-32643
    • Wang, G.1
  • 45
    • 27944487110 scopus 로고    scopus 로고
    • Spermicidal activity of dermaseptins
    • DOI 10.1016/j.contraception.2005.06.055, PII S0010782405002507
    • Zairi A, Belaid A, Gahbiche A, Hani K. Spermicidal activity of dermaseptins. Contraception 2005;72:447-453. (Pubitemid 41676836)
    • (2005) Contraception , vol.72 , Issue.6 , pp. 447-453
    • Zairi, A.1    Belaid, A.2    Gahbiche, A.3    Hani, K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.