Garcinia benzophenones inhibit the growth of human colon cancer cells and synergize with sulindac sulfide and turmeric

Anti-Cancer Agents in Medicinal Chemistry

Volumn 13, Issue 10, 2013, Pages 1540-1550

  Einbond, Linda Saxe ^a,b,c   Mighty, Jason ^b   Kashiwazaki, Ryota ^a   Figueroa, Mario ^b,d   Jalees, Filza ^b   Acuna, Ulyana Munoz ^b   LeGendre, Onica ^b   Foster, David A ^b   Kennelly, Edward J ^b  

^a New York Presbyterian Columbia University Medical Center   (United States)

^b CITY UNIVERSITY OF NEW YORK   (United States)

^c NEW YORK BOTANICAL GARDEN   (United States)

^d UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

And turmeric; Benzophenone; Celecoxib; Endoplasmic reticulum; Garcinia; Rapamycin; Sulindac sulfide; Synergy

Indexed keywords

BENZOPHENONE; CELECOXIB; GARCINIA XANTHOCHYMUS EXTRACT; GUTTIFERONE A; GUTTIFERONE E; PLANT EXTRACT; PLANT MEDICINAL PRODUCT; RAPAMYCIN; SULINDAC SULFIDE; TURMERIC; UNCLASSIFIED DRUG; XANTHOCHYMOL;

ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CANCER GROWTH; CELL GROWTH; CELL PROLIFERATION; COLON CANCER; CONTROLLED STUDY; DPPH RADICAL SCAVENGING ASSAY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN CELL; IC 50; INTESTINE EPITHELIUM CELL; PROTEIN PHOSPHORYLATION; WESTERN BLOTTING;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BENZOPHENONES; BUTADIENES; CELL LINE, TUMOR; CURCUMA; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; ENDOPLASMIC RETICULUM; ENZYME INHIBITORS; EPITHELIAL CELLS; GARCINIA; GENE EXPRESSION REGULATION, NEOPLASTIC; HEPARIN; HUMANS; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; MITOGEN-ACTIVATED PROTEIN KINASES; MULTIPROTEIN COMPLEXES; NITRILES; PHOSPHOPROTEINS; PLANT EXTRACTS; PYRAZOLES; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES; SULINDAC; TOR SERINE-THREONINE KINASES;

EID: 84898928457     PISSN: 18715206     EISSN: 18755992     Source Type: Journal    
DOI: 10.2174/18715206113139990095     Document Type: Article

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