-
1
-
-
79961004610
-
Molecular mechanisms of lymphangiogenesis in development and cancer
-
10.1387/ijdb.103226ia 21858772
-
Albrecht I, Christofori G (2011) Molecular mechanisms of lymphangiogenesis in development and cancer. Int J Dev Biol 55(4-5):483-494. doi: 10.1387/ijdb.103226ia
-
(2011)
Int J Dev Biol
, vol.55
, Issue.4-5
, pp. 483-494
-
-
Albrecht, I.1
Christofori, G.2
-
2
-
-
81255188905
-
The lymphatic vasculature in disease
-
10.1038/nm.2545 22064427
-
Alitalo K (2011) The lymphatic vasculature in disease. Nat Med 17(11):1371-1380. doi: 10.1038/nm.2545
-
(2011)
Nat Med
, vol.17
, Issue.11
, pp. 1371-1380
-
-
Alitalo, K.1
-
3
-
-
33748771724
-
New insights into the molecular control of the lymphatic vascular system and its role in disease
-
10.1038/sj.jid.5700464 16983326
-
Cueni LN, Detmar M (2006) New insights into the molecular control of the lymphatic vascular system and its role in disease. J Invest Dermatol 126(10):2167-2177. doi: 10.1038/sj.jid.5700464
-
(2006)
J Invest Dermatol
, vol.126
, Issue.10
, pp. 2167-2177
-
-
Cueni, L.N.1
Detmar, M.2
-
4
-
-
56049090304
-
Chapter 1. Inflammation, angiogenesis, and lymphangiogenesis
-
10.1016/S0076-6879(08)03001-2 19022053
-
Halin C, Detmar M (2008) Chapter 1. Inflammation, angiogenesis, and lymphangiogenesis. Methods Enzymol 445:1-25. doi: 10.1016/S0076-6879(08)03001-2
-
(2008)
Methods Enzymol
, vol.445
, pp. 1-25
-
-
Halin, C.1
Detmar, M.2
-
5
-
-
0037331713
-
Identification of vascular lineage-specific genes by transcriptional profiling of isolated blood vascular and lymphatic endothelial cells
-
10.1016/S0002-9440(10)63851-5 1851142 12547715
-
Hirakawa S, Hong YK, Harvey N, Schacht V, Matsuda K, Libermann T, Detmar M (2003) Identification of vascular lineage-specific genes by transcriptional profiling of isolated blood vascular and lymphatic endothelial cells. Am J Pathol 162(2):575-586. doi: 10.1016/S0002-9440(10)63851-5
-
(2003)
Am J Pathol
, vol.162
, Issue.2
, pp. 575-586
-
-
Hirakawa, S.1
Hong, Y.K.2
Harvey, N.3
Schacht, V.4
Matsuda, K.5
Libermann, T.6
Detmar, M.7
-
6
-
-
0035903330
-
Isolation and characterization of dermal lymphatic and blood endothelial cells reveal stable and functionally specialized cell lineages
-
2195953 11560995
-
Kriehuber E, Breiteneder-Geleff S, Groeger M, Soleiman A, Schoppmann SF, Stingl G, Kerjaschki D, Maurer D (2001) Isolation and characterization of dermal lymphatic and blood endothelial cells reveal stable and functionally specialized cell lineages. J Exp Med 194(6):797-808
-
(2001)
J Exp Med
, vol.194
, Issue.6
, pp. 797-808
-
-
Kriehuber, E.1
Breiteneder-Geleff, S.2
Groeger, M.3
Soleiman, A.4
Schoppmann, S.F.5
Stingl, G.6
Kerjaschki, D.7
Maurer, D.8
-
7
-
-
18544386859
-
Lymphatic endothelial reprogramming of vascular endothelial cells by the Prox-1 homeobox transcription factor
-
125413 12198161
-
Petrova TV, Makinen T, Makela TP, Saarela J, Virtanen I, Ferrell RE, Finegold DN, Kerjaschki D, Yla-Herttuala S, Alitalo K (2002) Lymphatic endothelial reprogramming of vascular endothelial cells by the Prox-1 homeobox transcription factor. EMBO J 21(17):4593-4599
-
(2002)
EMBO J
, vol.21
, Issue.17
, pp. 4593-4599
-
-
Petrova, T.V.1
Makinen, T.2
Makela, T.P.3
Saarela, J.4
Virtanen, I.5
Ferrell, R.E.6
Finegold, D.N.7
Kerjaschki, D.8
Yla-Herttuala, S.9
Alitalo, K.10
-
8
-
-
0242624291
-
Isolated lymphatic endothelial cells transduce growth, survival and migratory signals via the VEGF-C/D receptor VEGFR-3
-
10.1093/emboj/20.17.4762 125596 11532940
-
Makinen T, Veikkola T, Mustjoki S, Karpanen T, Catimel B, Nice EC, Wise L, Mercer A, Kowalski H, Kerjaschki D, Stacker SA, Achen MG, Alitalo K (2001) Isolated lymphatic endothelial cells transduce growth, survival and migratory signals via the VEGF-C/D receptor VEGFR-3. EMBO J 20(17):4762-4773. doi: 10.1093/emboj/20.17.4762
-
(2001)
EMBO J
, vol.20
, Issue.17
, pp. 4762-4773
-
-
Makinen, T.1
Veikkola, T.2
Mustjoki, S.3
Karpanen, T.4
Catimel, B.5
Nice, E.C.6
Wise, L.7
Mercer, A.8
Kowalski, H.9
Kerjaschki, D.10
Stacker, S.A.11
Achen, M.G.12
Alitalo, K.13
-
9
-
-
76749083490
-
Lymphangiogenesis: Molecular mechanisms and future promise
-
10.1016/j.cell.2010.01.045 20178740
-
Tammela T, Alitalo K (2010) Lymphangiogenesis: molecular mechanisms and future promise. Cell 140(4):460-476. doi: 10.1016/j.cell.2010.01.045
-
(2010)
Cell
, vol.140
, Issue.4
, pp. 460-476
-
-
Tammela, T.1
Alitalo, K.2
-
10
-
-
0028938746
-
Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development
-
42208 7724599
-
Kaipainen A, Korhonen J, Mustonen T, van Hinsbergh VW, Fang GH, Dumont D, Breitman M, Alitalo K (1995) Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development. Proc Natl Acad Sci USA 92(8):3566-3570
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, Issue.8
, pp. 3566-3570
-
-
Kaipainen, A.1
Korhonen, J.2
Mustonen, T.3
Van Hinsbergh, V.W.4
Fang, G.H.5
Dumont, D.6
Breitman, M.7
Alitalo, K.8
-
11
-
-
0033814892
-
VEGF-C and VEGF-D expression in neuroendocrine cells and their receptor, VEGFR-3, in fenestrated blood vessels in human tissues
-
10.1096/fj.99-1049com 11023993
-
Partanen TA, Arola J, Saaristo A, Jussila L, Ora A, Miettinen M, Stacker SA, Achen MG, Alitalo K (2000) VEGF-C and VEGF-D expression in neuroendocrine cells and their receptor, VEGFR-3, in fenestrated blood vessels in human tissues. FASEB J 14(13):2087-2096. doi: 10.1096/fj.99-1049com
-
(2000)
FASEB J
, vol.14
, Issue.13
, pp. 2087-2096
-
-
Partanen, T.A.1
Arola, J.2
Saaristo, A.3
Jussila, L.4
Ora, A.5
Miettinen, M.6
Stacker, S.A.7
Achen, M.G.8
Alitalo, K.9
-
12
-
-
0033578853
-
Prox1 function is required for the development of the murine lymphatic system
-
10499794
-
Wigle JT, Oliver G (1999) Prox1 function is required for the development of the murine lymphatic system. Cell 98(6):769-778
-
(1999)
Cell
, vol.98
, Issue.6
, pp. 769-778
-
-
Wigle, J.T.1
Oliver, G.2
-
13
-
-
3042780203
-
Lymphatic reprogramming of blood vascular endothelium by Kaposi sarcoma-associated herpesvirus
-
15220917
-
Hong YK, Foreman K, Shin JW, Hirakawa S, Curry CL, Sage DR, Libermann T, Dezube BJ, Fingeroth JD, Detmar M (2004) Lymphatic reprogramming of blood vascular endothelium by Kaposi sarcoma-associated herpesvirus. Nat Genet 36(7):683-685
-
(2004)
Nat Genet
, vol.36
, Issue.7
, pp. 683-685
-
-
Hong, Y.K.1
Foreman, K.2
Shin, J.W.3
Hirakawa, S.4
Curry, C.L.5
Sage, D.R.6
Libermann, T.7
Dezube, B.J.8
Fingeroth, J.D.9
Detmar, M.10
-
14
-
-
0033593793
-
LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan
-
2132933 10037799
-
Banerji S, Ni J, Wang SX, Clasper S, Su J, Tammi R, Jones M, Jackson DG (1999) LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan. J Cell Biol 144(4):789-801
-
(1999)
J Cell Biol
, vol.144
, Issue.4
, pp. 789-801
-
-
Banerji, S.1
Ni, J.2
Wang, S.X.3
Clasper, S.4
Su, J.5
Tammi, R.6
Jones, M.7
Jackson, D.G.8
-
15
-
-
33846140150
-
Normal lymphatic development and function in mice deficient for the lymphatic hyaluronan receptor LYVE-1
-
10.1128/MCB.01503-06 1800809 17101772
-
Gale NW, Prevo R, Espinosa J, Ferguson DJ, Dominguez MG, Yancopoulos GD, Thurston G, Jackson DG (2007) Normal lymphatic development and function in mice deficient for the lymphatic hyaluronan receptor LYVE-1. Mol Cell Biol 27(2):595-604. doi: 10.1128/MCB.01503-06
-
(2007)
Mol Cell Biol
, vol.27
, Issue.2
, pp. 595-604
-
-
Gale, N.W.1
Prevo, R.2
Espinosa, J.3
Ferguson, D.J.4
Dominguez, M.G.5
Yancopoulos, G.D.6
Thurston, G.7
Jackson, D.G.8
-
16
-
-
13244292521
-
PDZ interaction site in ephrinB2 is required for the remodeling of lymphatic vasculature
-
10.1101/gad.330105 546518 15687262
-
Makinen T, Adams RH, Bailey J, Lu Q, Ziemiecki A, Alitalo K, Klein R, Wilkinson GA (2005) PDZ interaction site in ephrinB2 is required for the remodeling of lymphatic vasculature. Genes Dev 19(3):397-410. doi: 10.1101/gad.330105
-
(2005)
Genes Dev
, vol.19
, Issue.3
, pp. 397-410
-
-
Makinen, T.1
Adams, R.H.2
Bailey, J.3
Lu, Q.4
Ziemiecki, A.5
Alitalo, K.6
Klein, R.7
Wilkinson, G.A.8
-
17
-
-
0035890540
-
LYVE-1 is not restricted to the lymph vessels: Expression in normal liver blood sinusoids and down-regulation in human liver cancer and cirrhosis
-
11719431
-
Mouta Carreira C, Nasser SM, di Tomaso E, Padera TP, Boucher Y, Tomarev SI, Jain RK (2001) LYVE-1 is not restricted to the lymph vessels: expression in normal liver blood sinusoids and down-regulation in human liver cancer and cirrhosis. Cancer Res 61(22):8079-8084
-
(2001)
Cancer Res
, vol.61
, Issue.22
, pp. 8079-8084
-
-
Mouta Carreira, C.1
Nasser, S.M.2
Di Tomaso, E.3
Padera, T.P.4
Boucher, Y.5
Tomarev, S.I.6
Jain, R.K.7
-
18
-
-
0032937233
-
Angiosarcomas express mixed endothelial phenotypes of blood and lymphatic capillaries: Podoplanin as a specific marker for lymphatic endothelium
-
10.1016/S0002-9440(10)65285-6 1849992 10027397
-
Breiteneder-Geleff S, Soleiman A, Kowalski H, Horvat R, Amann G, Kriehuber E, Diem K, Weninger W, Tschachler E, Alitalo K, Kerjaschki D (1999) Angiosarcomas express mixed endothelial phenotypes of blood and lymphatic capillaries: podoplanin as a specific marker for lymphatic endothelium. Am J Pathol 154(2):385-394. doi: 10.1016/S0002-9440(10)65285-6
-
(1999)
Am J Pathol
, vol.154
, Issue.2
, pp. 385-394
-
-
Breiteneder-Geleff, S.1
Soleiman, A.2
Kowalski, H.3
Horvat, R.4
Amann, G.5
Kriehuber, E.6
Diem, K.7
Weninger, W.8
Tschachler, E.9
Alitalo, K.10
Kerjaschki, D.11
-
19
-
-
0041312675
-
T1alpha/podoplanin deficiency disrupts normal lymphatic vasculature formation and causes lymphedema
-
10.1093/emboj/cdg342 165612 12853470
-
Schacht V, Ramirez MI, Hong YK, Hirakawa S, Feng D, Harvey N, Williams M, Dvorak AM, Dvorak HF, Oliver G, Detmar M (2003) T1alpha/podoplanin deficiency disrupts normal lymphatic vasculature formation and causes lymphedema. EMBO J 22(14):3546-3556. doi: 10.1093/emboj/cdg342
-
(2003)
EMBO J
, vol.22
, Issue.14
, pp. 3546-3556
-
-
Schacht, V.1
Ramirez, M.I.2
Hong, Y.K.3
Hirakawa, S.4
Feng, D.5
Harvey, N.6
Williams, M.7
Dvorak, A.M.8
Dvorak, H.F.9
Oliver, G.10
Detmar, M.11
-
20
-
-
53149135427
-
Lymphatic precollectors contain a novel, specialized subpopulation of podoplanin low, CCL27-expressing lymphatic endothelial cells
-
10.2353/ajpath.2008.080101 2543086 18772332
-
Wick N, Haluza D, Gurnhofer E, Raab I, Kasimir MT, Prinz M, Steiner CW, Reinisch C, Howorka A, Giovanoli P, Buchsbaum S, Krieger S, Tschachler E, Petzelbauer P, Kerjaschki D (2008) Lymphatic precollectors contain a novel, specialized subpopulation of podoplanin low, CCL27-expressing lymphatic endothelial cells. Am J Pathol 173(4):1202-1209. doi: 10.2353/ajpath.2008.080101
-
(2008)
Am J Pathol
, vol.173
, Issue.4
, pp. 1202-1209
-
-
Wick, N.1
Haluza, D.2
Gurnhofer, E.3
Raab, I.4
Kasimir, M.T.5
Prinz, M.6
Steiner, C.W.7
Reinisch, C.8
Howorka, A.9
Giovanoli, P.10
Buchsbaum, S.11
Krieger, S.12
Tschachler, E.13
Petzelbauer, P.14
Kerjaschki, D.15
-
21
-
-
0037631737
-
Novel expression of vascular endothelial growth factor receptor (VEGFR)-3 and VEGF-C on corneal dendritic cells
-
10.1016/S0002-9440(10)63630-9 1868166 12819011
-
Hamrah P, Chen L, Zhang Q, Dana MR (2003) Novel expression of vascular endothelial growth factor receptor (VEGFR)-3 and VEGF-C on corneal dendritic cells. Am J Pathol 163(1):57-68. doi: 10.1016/S0002-9440(10)63630-9
-
(2003)
Am J Pathol
, vol.163
, Issue.1
, pp. 57-68
-
-
Hamrah, P.1
Chen, L.2
Zhang, Q.3
Dana, M.R.4
-
22
-
-
33746621996
-
Nonvascular VEGF receptor 3 expression by corneal epithelium maintains avascularity and vision
-
10.1073/pnas.0506112103 1544098 16849433
-
Cursiefen C, Chen L, Saint-Geniez M, Hamrah P, Jin Y, Rashid S, Pytowski B, Persaud K, Wu Y, Streilein JW, Dana R (2006) Nonvascular VEGF receptor 3 expression by corneal epithelium maintains avascularity and vision. Proc Natl Acad Sci U S A 103(30):11405-11410. doi: 10.1073/pnas.0506112103
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, Issue.30
, pp. 11405-11410
-
-
Cursiefen, C.1
Chen, L.2
Saint-Geniez, M.3
Hamrah, P.4
Jin, Y.5
Rashid, S.6
Pytowski, B.7
Persaud, K.8
Wu, Y.9
Streilein, J.W.10
Dana, R.11
-
23
-
-
0036803310
-
Prox1 is an early specific marker for the developing liver and pancreas in the mammalian foregut endoderm
-
12351178
-
Burke Z, Oliver G (2002) Prox1 is an early specific marker for the developing liver and pancreas in the mammalian foregut endoderm. Mech Dev 118(1-2):147-155
-
(2002)
Mech Dev
, vol.118
, Issue.1-2
, pp. 147-155
-
-
Burke, Z.1
Oliver, G.2
-
24
-
-
33846928008
-
Prox1 expression patterns in the developing and adult murine brain
-
10.1002/dvdy.21024 17117441
-
Lavado A, Oliver G (2007) Prox1 expression patterns in the developing and adult murine brain. Dev Dyn 236(2):518-524. doi: 10.1002/dvdy.21024
-
(2007)
Dev Dyn
, vol.236
, Issue.2
, pp. 518-524
-
-
Lavado, A.1
Oliver, G.2
-
25
-
-
34247238939
-
A prospero-related homeobox gene Prox-1 is expressed during postnatal brain development as well as in the adult rodent brain
-
10.1016/j.neuroscience.2007.02.002 17368742
-
Galeeva A, Treuter E, Tomarev S, Pelto-Huikko M (2007) A prospero-related homeobox gene Prox-1 is expressed during postnatal brain development as well as in the adult rodent brain. Neuroscience 146(2):604-616. doi: 10.1016/j.neuroscience.2007.02.002
-
(2007)
Neuroscience
, vol.146
, Issue.2
, pp. 604-616
-
-
Galeeva, A.1
Treuter, E.2
Tomarev, S.3
Pelto-Huikko, M.4
-
26
-
-
33644808015
-
Novel expression and characterization of lymphatic vessel endothelial hyaluronate receptor 1 (LYVE-1) by conjunctival cells
-
10.1167/iovs.05-0975 1397798 16303945
-
Chen L, Cursiefen C, Barabino S, Zhang Q, Dana MR (2005) Novel expression and characterization of lymphatic vessel endothelial hyaluronate receptor 1 (LYVE-1) by conjunctival cells. Invest Ophthalmol Vis Sci 46(12):4536-4540. doi: 10.1167/iovs.05-0975
-
(2005)
Invest Ophthalmol Vis Sci
, vol.46
, Issue.12
, pp. 4536-4540
-
-
Chen, L.1
Cursiefen, C.2
Barabino, S.3
Zhang, Q.4
Dana, M.R.5
-
27
-
-
33947520741
-
Angiogenic role of LYVE-1-positive macrophages in adipose tissue
-
10.1161/01.RES.0000259564.92792.93 17272806
-
Cho CH, Koh YJ, Han J, Sung HK, Jong Lee H, Morisada T, Schwendener RA, Brekken RA, Kang G, Oike Y, Choi TS, Suda T, Yoo OJ, Koh GY (2007) Angiogenic role of LYVE-1-positive macrophages in adipose tissue. Circ Res 100(4):e47-e57. doi: 10.1161/01.RES.0000259564.92792.93
-
(2007)
Circ Res
, vol.100
, Issue.4
-
-
Cho, C.H.1
Koh, Y.J.2
Han, J.3
Sung, H.K.4
Jong Lee, H.5
Morisada, T.6
Schwendener, R.A.7
Brekken, R.A.8
Kang, G.9
Oike, Y.10
Choi, T.S.11
Suda, T.12
Yoo, O.J.13
Koh, G.Y.14
-
28
-
-
33646008309
-
Lymphatic endothelium-specific hyaluronan receptor LYVE-1 is expressed by stabilin-1+, F4/80+, CD11b+ macrophages in malignant tumours and wound healing tissue in vivo and in bone marrow cultures in vitro: Implications for the assessment of lymphangiogenesis
-
10.1002/path.1942 16482496
-
Schledzewski K, Falkowski M, Moldenhauer G, Metharom P, Kzhyshkowska J, Ganss R, Demory A, Falkowska-Hansen B, Kurzen H, Ugurel S, Geginat G, Arnold B, Goerdt S (2006) Lymphatic endothelium-specific hyaluronan receptor LYVE-1 is expressed by stabilin-1+, F4/80+, CD11b+ macrophages in malignant tumours and wound healing tissue in vivo and in bone marrow cultures in vitro: implications for the assessment of lymphangiogenesis. J Pathol 209(1):67-77. doi: 10.1002/path.1942
-
(2006)
J Pathol
, vol.209
, Issue.1
, pp. 67-77
-
-
Schledzewski, K.1
Falkowski, M.2
Moldenhauer, G.3
Metharom, P.4
Kzhyshkowska, J.5
Ganss, R.6
Demory, A.7
Falkowska-Hansen, B.8
Kurzen, H.9
Ugurel, S.10
Geginat, G.11
Arnold, B.12
Goerdt, S.13
-
29
-
-
0030160454
-
T1 alpha protein is developmentally regulated and expressed by alveolar type i cells, choroid plexus, and ciliary epithelia of adult rats
-
10.1165/ajrcmb.14.6.8652186 8652186
-
Williams MC, Cao Y, Hinds A, Rishi AK, Wetterwald A (1996) T1 alpha protein is developmentally regulated and expressed by alveolar type I cells, choroid plexus, and ciliary epithelia of adult rats. Am J Respir Cell Mol Biol 14(6):577-585. doi: 10.1165/ajrcmb.14.6.8652186
-
(1996)
Am J Respir Cell Mol Biol
, vol.14
, Issue.6
, pp. 577-585
-
-
Williams, M.C.1
Cao, Y.2
Hinds, A.3
Rishi, A.K.4
Wetterwald, A.5
-
30
-
-
84863410656
-
The expression of podoplanin and classic cadherins in the mouse brain
-
10.1111/j.1469-7580.2012.01484.x 22352427
-
Kaji C, Tomooka M, Kato Y, Kojima H, Sawa Y (2012) The expression of podoplanin and classic cadherins in the mouse brain. J Anat 220(5):435-446. doi: 10.1111/j.1469-7580.2012.01484.x
-
(2012)
J Anat
, vol.220
, Issue.5
, pp. 435-446
-
-
Kaji, C.1
Tomooka, M.2
Kato, Y.3
Kojima, H.4
Sawa, Y.5
-
31
-
-
0037376154
-
T1alpha, a lung type i cell differentiation gene, is required for normal lung cell proliferation and alveolus formation at birth
-
12654292
-
Ramirez MI, Millien G, Hinds A, Cao Y, Seldin DC, Williams MC (2003) T1alpha, a lung type I cell differentiation gene, is required for normal lung cell proliferation and alveolus formation at birth. Dev Biol 256(1):61-72
-
(2003)
Dev Biol
, vol.256
, Issue.1
, pp. 61-72
-
-
Ramirez, M.I.1
Millien, G.2
Hinds, A.3
Cao, Y.4
Seldin, D.C.5
Williams, M.C.6
-
32
-
-
38849151074
-
Role of CD30 in B/T segregation in the spleen
-
18025198
-
Bekiaris V, Withers D, Glanville SH, McConnell FM, Parnell SM, Kim MY, Gaspal FM, Jenkinson E, Sweet C, Anderson G, Lane PJ (2007) Role of CD30 in B/T segregation in the spleen. J Immunol 179(11):7535-7543
-
(2007)
J Immunol
, vol.179
, Issue.11
, pp. 7535-7543
-
-
Bekiaris, V.1
Withers, D.2
Glanville, S.H.3
McConnell, F.M.4
Parnell, S.M.5
Kim, M.Y.6
Gaspal, F.M.7
Jenkinson, E.8
Sweet, C.9
Anderson, G.10
Lane, P.J.11
-
33
-
-
84859926294
-
Transcriptional profiling of stroma from inflamed and resting lymph nodes defines immunological hallmarks
-
10.1038/ni.2262 3366863 22466668
-
Malhotra D, Fletcher AL, Astarita J, Lukacs-Kornek V, Tayalia P, Gonzalez SF, Elpek KG, Chang SK, Knoblich K, Hemler ME, Brenner MB, Carroll MC, Mooney DJ, Turley SJ (2012) Transcriptional profiling of stroma from inflamed and resting lymph nodes defines immunological hallmarks. Nat Immunol 13(5):499-510. doi: 10.1038/ni.2262
-
(2012)
Nat Immunol
, vol.13
, Issue.5
, pp. 499-510
-
-
Malhotra, D.1
Fletcher, A.L.2
Astarita, J.3
Lukacs-Kornek, V.4
Tayalia, P.5
Gonzalez, S.F.6
Elpek, K.G.7
Chang, S.K.8
Knoblich, K.9
Hemler, M.E.10
Brenner, M.B.11
Carroll, M.C.12
Mooney, D.J.13
Turley, S.J.14
-
34
-
-
77956912413
-
A distinct subset of podoplanin (gp38) expressing F4/80+ macrophages mediate phagocytosis and are induced following zymosan peritonitis
-
10.1016/j.febslet.2010.07.053 20682314
-
Hou TZ, Bystrom J, Sherlock JP, Qureshi O, Parnell SM, Anderson G, Gilroy DW, Buckley CD (2010) A distinct subset of podoplanin (gp38) expressing F4/80+ macrophages mediate phagocytosis and are induced following zymosan peritonitis. FEBS Lett 584(18):3955-3961. doi: 10.1016/j.febslet.2010.07.053
-
(2010)
FEBS Lett
, vol.584
, Issue.18
, pp. 3955-3961
-
-
Hou, T.Z.1
Bystrom, J.2
Sherlock, J.P.3
Qureshi, O.4
Parnell, S.M.5
Anderson, G.6
Gilroy, D.W.7
Buckley, C.D.8
-
35
-
-
84863412801
-
Podoplanin-expressing inflammatory macrophages activate murine platelets via CLEC-2
-
10.1111/j.1538-7836.2011.04614.x 3433653 22212362
-
Kerrigan AM, Navarro-Nunez L, Pyz E, Finney BA, Willment JA, Watson SP, Brown GD (2012) Podoplanin-expressing inflammatory macrophages activate murine platelets via CLEC-2. J Thromb Haemost 10(3):484-486. doi: 10.1111/j.1538-7836. 2011.04614.x
-
(2012)
J Thromb Haemost
, vol.10
, Issue.3
, pp. 484-486
-
-
Kerrigan, A.M.1
Navarro-Nunez, L.2
Pyz, E.3
Finney, B.A.4
Willment, J.A.5
Watson, S.P.6
Brown, G.D.7
-
36
-
-
84355166761
-
Th17 cells induce ectopic lymphoid follicles in central nervous system tissue inflammation
-
10.1016/j.immuni.2011.10.015 3422678 22177922
-
Peters A, Pitcher LA, Sullivan JM, Mitsdoerffer M, Acton SE, Franz B, Wucherpfennig K, Turley S, Carroll MC, Sobel RA, Bettelli E, Kuchroo VK (2011) Th17 cells induce ectopic lymphoid follicles in central nervous system tissue inflammation. Immunity 35(6):986-996. doi: 10.1016/j.immuni.2011.10.015
-
(2011)
Immunity
, vol.35
, Issue.6
, pp. 986-996
-
-
Peters, A.1
Pitcher, L.A.2
Sullivan, J.M.3
Mitsdoerffer, M.4
Acton, S.E.5
Franz, B.6
Wucherpfennig, K.7
Turley, S.8
Carroll, M.C.9
Sobel, R.A.10
Bettelli, E.11
Kuchroo, V.K.12
-
37
-
-
38649122731
-
Podoplanin is a useful diagnostic marker for epithelioid hemangioendothelioma of the liver
-
10.1038/modpathol.3800986 18084256
-
Fujii T, Zen Y, Sato Y, Sasaki M, Enomae M, Minato H, Masuda S, Uehara T, Katsuyama T, Nakanuma Y (2008) Podoplanin is a useful diagnostic marker for epithelioid hemangioendothelioma of the liver. Mod Pathol 21(2):125-130. doi: 10.1038/modpathol.3800986
-
(2008)
Mod Pathol
, vol.21
, Issue.2
, pp. 125-130
-
-
Fujii, T.1
Zen, Y.2
Sato, Y.3
Sasaki, M.4
Enomae, M.5
Minato, H.6
Masuda, S.7
Uehara, T.8
Katsuyama, T.9
Nakanuma, Y.10
-
38
-
-
44449138380
-
Markers for microscopic imaging of lymphangiogenesis and angiogenesis
-
10.1196/annals.1413.001 18519955
-
Baluk P, McDonald DM (2008) Markers for microscopic imaging of lymphangiogenesis and angiogenesis. Ann N Y Acad Sci 1131:1-12. doi: 10.1196/annals.1413.001
-
(2008)
Ann N y Acad Sci
, vol.1131
, pp. 1-12
-
-
Baluk, P.1
McDonald, D.M.2
-
39
-
-
54749126267
-
A novel gene expression profile in lymphatics associated with tumor growth and nodal metastasis
-
10.1158/0008-5472.CAN-07-6506 18794116
-
Clasper S, Royston D, Baban D, Cao Y, Ewers S, Butz S, Vestweber D, Jackson DG (2008) A novel gene expression profile in lymphatics associated with tumor growth and nodal metastasis. Cancer Res 68(18):7293-7303. doi: 10.1158/0008-5472.CAN-07-6506
-
(2008)
Cancer Res
, vol.68
, Issue.18
, pp. 7293-7303
-
-
Clasper, S.1
Royston, D.2
Baban, D.3
Cao, Y.4
Ewers, S.5
Butz, S.6
Vestweber, D.7
Jackson, D.G.8
-
40
-
-
10344227188
-
IL-3 induces expression of lymphatic markers Prox-1 and podoplanin in human endothelial cells
-
15585837
-
Groger M, Loewe R, Holnthoner W, Embacher R, Pillinger M, Herron GS, Wolff K, Petzelbauer P (2004) IL-3 induces expression of lymphatic markers Prox-1 and podoplanin in human endothelial cells. J Immunol 173(12):7161-7169
-
(2004)
J Immunol
, vol.173
, Issue.12
, pp. 7161-7169
-
-
Groger, M.1
Loewe, R.2
Holnthoner, W.3
Embacher, R.4
Pillinger, M.5
Herron, G.S.6
Wolff, K.7
Petzelbauer, P.8
-
41
-
-
20144369085
-
Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation
-
10.1172/JCI22037 544601 15668734
-
Baluk P, Tammela T, Ator E, Lyubynska N, Achen MG, Hicklin DJ, Jeltsch M, Petrova TV, Pytowski B, Stacker SA, Yla-Herttuala S, Jackson DG, Alitalo K, McDonald DM (2005) Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation. J Clin Invest 115(2):247-257. doi: 10.1172/JCI22037
-
(2005)
J Clin Invest
, vol.115
, Issue.2
, pp. 247-257
-
-
Baluk, P.1
Tammela, T.2
Ator, E.3
Lyubynska, N.4
Achen, M.G.5
Hicklin, D.J.6
Jeltsch, M.7
Petrova, T.V.8
Pytowski, B.9
Stacker, S.A.10
Yla-Herttuala, S.11
Jackson, D.G.12
Alitalo, K.13
McDonald, D.M.14
-
42
-
-
36348957448
-
Inflammation-induced uptake and degradation of the lymphatic endothelial hyaluronan receptor LYVE-1
-
10.1074/jbc.M702889200 17884820
-
Johnson LA, Prevo R, Clasper S, Jackson DG (2007) Inflammation-induced uptake and degradation of the lymphatic endothelial hyaluronan receptor LYVE-1. J Biol Chem 282(46):33671-33680. doi: 10.1074/jbc.M702889200
-
(2007)
J Biol Chem
, vol.282
, Issue.46
, pp. 33671-33680
-
-
Johnson, L.A.1
Prevo, R.2
Clasper, S.3
Jackson, D.G.4
-
43
-
-
79960127293
-
Tissue inflammation modulates gene expression of lymphatic endothelial cells and dendritic cell migration in a stimulus-dependent manner
-
10.1182/blood-2010-12-326447 21596851
-
Vigl B, Aebischer D, Nitschke M, Iolyeva M, Rothlin T, Antsiferova O, Halin C (2011) Tissue inflammation modulates gene expression of lymphatic endothelial cells and dendritic cell migration in a stimulus-dependent manner. Blood 118(1):205-215. doi: 10.1182/blood-2010-12-326447
-
(2011)
Blood
, vol.118
, Issue.1
, pp. 205-215
-
-
Vigl, B.1
Aebischer, D.2
Nitschke, M.3
Iolyeva, M.4
Rothlin, T.5
Antsiferova, O.6
Halin, C.7
-
44
-
-
79955957828
-
An important role of lymphatic vessel activation in limiting acute inflammation
-
10.1182/blood-2010-10-316356 3099581 21364190
-
Huggenberger R, Siddiqui SS, Brander D, Ullmann S, Zimmermann K, Antsiferova M, Werner S, Alitalo K, Detmar M (2011) An important role of lymphatic vessel activation in limiting acute inflammation. Blood 117(17):4667-4678. doi: 10.1182/blood-2010-10-316356
-
(2011)
Blood
, vol.117
, Issue.17
, pp. 4667-4678
-
-
Huggenberger, R.1
Siddiqui, S.S.2
Brander, D.3
Ullmann, S.4
Zimmermann, K.5
Antsiferova, M.6
Werner, S.7
Alitalo, K.8
Detmar, M.9
-
45
-
-
75649083174
-
Inflammation induces lymphangiogenesis through up-regulation of VEGFR-3 mediated by NF-kappaB and Prox1
-
10.1182/blood-2008-12-196840 2808162 19901262
-
Flister MJ, Wilber A, Hall KL, Iwata C, Miyazono K, Nisato RE, Pepper MS, Zawieja DC, Ran S (2010) Inflammation induces lymphangiogenesis through up-regulation of VEGFR-3 mediated by NF-kappaB and Prox1. Blood 115(2):418-429. doi: 10.1182/blood-2008-12-196840
-
(2010)
Blood
, vol.115
, Issue.2
, pp. 418-429
-
-
Flister, M.J.1
Wilber, A.2
Hall, K.L.3
Iwata, C.4
Miyazono, K.5
Nisato, R.E.6
Pepper, M.S.7
Zawieja, D.C.8
Ran, S.9
-
46
-
-
84887105529
-
Expansion of the lymphatic vasculature in cancer and inflammation: New opportunities for in vivo imaging and drug delivery
-
10.1016/j.jconrel.2013.04.027 23665257
-
Proulx ST, Luciani P, Dieterich LC, Karaman S, Leroux JC, Detmar M (2013) Expansion of the lymphatic vasculature in cancer and inflammation: new opportunities for in vivo imaging and drug delivery. J Control Release. doi: 10.1016/j.jconrel.2013.04.027
-
(2013)
J Control Release
-
-
Proulx, S.T.1
Luciani, P.2
Dieterich, L.C.3
Karaman, S.4
Leroux, J.C.5
Detmar, M.6
-
47
-
-
3843120939
-
Induction of cutaneous delayed-type hypersensitivity reactions in VEGF-A transgenic mice results in chronic skin inflammation associated with persistent lymphatic hyperplasia
-
10.1182/blood-2003-08-2964 15100155
-
Kunstfeld R, Hirakawa S, Hong YK, Schacht V, Lange-Asschenfeldt B, Velasco P, Lin C, Fiebiger E, Wei X, Wu Y, Hicklin D, Bohlen P, Detmar M (2004) Induction of cutaneous delayed-type hypersensitivity reactions in VEGF-A transgenic mice results in chronic skin inflammation associated with persistent lymphatic hyperplasia. Blood 104(4):1048-1057. doi: 10.1182/blood-2003-08-2964
-
(2004)
Blood
, vol.104
, Issue.4
, pp. 1048-1057
-
-
Kunstfeld, R.1
Hirakawa, S.2
Hong, Y.K.3
Schacht, V.4
Lange-Asschenfeldt, B.5
Velasco, P.6
Lin, C.7
Fiebiger, E.8
Wei, X.9
Wu, Y.10
Hicklin, D.11
Bohlen, P.12
Detmar, M.13
-
48
-
-
37249060635
-
Increased lymphangiogenesis in joints of mice with inflammatory arthritis
-
10.1186/ar2326 2246237 17997858
-
Zhang Q, Lu Y, Proulx ST, Guo R, Yao Z, Schwarz EM, Boyce BF, Xing L (2007) Increased lymphangiogenesis in joints of mice with inflammatory arthritis. Arthritis Res Ther 9(6):R118. doi: 10.1186/ar2326
-
(2007)
Arthritis Res Ther
, vol.9
, Issue.6
, pp. 118
-
-
Zhang, Q.1
Lu, Y.2
Proulx, S.T.3
Guo, R.4
Yao, Z.5
Schwarz, E.M.6
Boyce, B.F.7
Xing, L.8
-
49
-
-
0344197018
-
Distribution of lymphatic vessels in normal and arthritic human synovial tissues
-
1754407 14644866
-
Xu H, Edwards J, Banerji S, Prevo R, Jackson DG, Athanasou NA (2003) Distribution of lymphatic vessels in normal and arthritic human synovial tissues. Ann Rheum Dis 62(12):1227-1229
-
(2003)
Ann Rheum Dis
, vol.62
, Issue.12
, pp. 1227-1229
-
-
Xu, H.1
Edwards, J.2
Banerji, S.3
Prevo, R.4
Jackson, D.G.5
Athanasou, N.A.6
-
50
-
-
84886733460
-
Use of a whole-slide imaging system to assess the presence and alteration of lymphatic vessels in joint sections of arthritic mice
-
10.3109/10520295.2012.729864 3672261
-
Shi J, Liang Q, Wang Y, Mooney R, Boyce B, Xing L (2012) Use of a whole-slide imaging system to assess the presence and alteration of lymphatic vessels in joint sections of arthritic mice. Biotech Histochem. doi: 10.3109/10520295.2012.729864
-
(2012)
Biotech Histochem
-
-
Shi, J.1
Liang, Q.2
Wang, Y.3
Mooney, R.4
Boyce, B.5
Xing, L.6
-
51
-
-
84867359105
-
Inflammation-driven dermal lymphangiogenesis in atopic dermatitis is associated with CD11b+ macrophage recruitment and VEGF-C up-regulation in the IL-4-transgenic mouse model
-
10.1111/j.1549-8719.2012.00189.x 22574929
-
Shi VY, Bao L, Chan LS (2012) Inflammation-driven dermal lymphangiogenesis in atopic dermatitis is associated with CD11b+ macrophage recruitment and VEGF-C up-regulation in the IL-4-transgenic mouse model. Microcirculation 19(7):567-579. doi: 10.1111/j.1549-8719.2012.00189.x
-
(2012)
Microcirculation
, vol.19
, Issue.7
, pp. 567-579
-
-
Shi, V.Y.1
Bao, L.2
Chan, L.S.3
-
52
-
-
78049509438
-
Emerging roles of lymphatics in inflammatory bowel disease
-
10.1111/j.1749-6632.2010.05757.x 20961310
-
Alexander JS, Chaitanya GV, Grisham MB, Boktor M (2010) Emerging roles of lymphatics in inflammatory bowel disease. Ann N Y Acad Sci 1207(Suppl 1):E75-E85. doi: 10.1111/j.1749-6632.2010.05757.x
-
(2010)
Ann N y Acad Sci
, vol.1207
, Issue.SUPPL. 1
-
-
Alexander, J.S.1
Chaitanya, G.V.2
Grisham, M.B.3
Boktor, M.4
-
53
-
-
77951498347
-
Quantitative lymphatic vessel trait analysis suggests Vcam1 as candidate modifier gene of inflammatory bowel disease
-
10.1038/gene.2010.4 2865135 20220769
-
Jurisic G, Sundberg JP, Bleich A, Leiter EH, Broman KW, Buechler G, Alley L, Vestweber D, Detmar M (2010) Quantitative lymphatic vessel trait analysis suggests Vcam1 as candidate modifier gene of inflammatory bowel disease. Genes Immun 11(3):219-231. doi: 10.1038/gene.2010.4
-
(2010)
Genes Immun
, vol.11
, Issue.3
, pp. 219-231
-
-
Jurisic, G.1
Sundberg, J.P.2
Bleich, A.3
Leiter, E.H.4
Broman, K.W.5
Buechler, G.6
Alley, L.7
Vestweber, D.8
Detmar, M.9
-
54
-
-
0037011070
-
Vascular permeability factor/vascular endothelial growth factor induces lymphangiogenesis as well as angiogenesis
-
2194262 12461084
-
Nagy JA, Vasile E, Feng D, Sundberg C, Brown LF, Detmar MJ, Lawitts JA, Benjamin L, Tan X, Manseau EJ, Dvorak AM, Dvorak HF (2002) Vascular permeability factor/vascular endothelial growth factor induces lymphangiogenesis as well as angiogenesis. J Exp Med 196(11):1497-1506
-
(2002)
J Exp Med
, vol.196
, Issue.11
, pp. 1497-1506
-
-
Nagy, J.A.1
Vasile, E.2
Feng, D.3
Sundberg, C.4
Brown, L.F.5
Detmar, M.J.6
Lawitts, J.A.7
Benjamin, L.8
Tan, X.9
Manseau, E.J.10
Dvorak, A.M.11
Dvorak, H.F.12
-
55
-
-
84857232552
-
Inflammation-induced lymph node lymphangiogenesis is reversible
-
10.1016/j.ajpath.2011.11.010 3349879 22200615
-
Mumprecht V, Roudnicky F, Detmar M (2012) Inflammation-induced lymph node lymphangiogenesis is reversible. Am J Pathol 180(3):874-879. doi: 10.1016/j.ajpath.2011.11.010
-
(2012)
Am J Pathol
, vol.180
, Issue.3
, pp. 874-879
-
-
Mumprecht, V.1
Roudnicky, F.2
Detmar, M.3
-
56
-
-
84878219609
-
Lymphatic vessel memory stimulated by recurrent inflammation
-
10.1016/j.ajpath.2013.02.025
-
Kelley PM, Conner AL, Tempero RM (2013) Lymphatic vessel memory stimulated by recurrent inflammation. Am J Pathol. doi: 10.1016/j.ajpath.2013. 02.025
-
(2013)
Am J Pathol
-
-
Kelley, P.M.1
Conner, A.L.2
Tempero, R.M.3
-
57
-
-
17144402207
-
VEGF-A induces tumor and sentinel lymph node lymphangiogenesis and promotes lymphatic metastasis
-
10.1084/jem.20041896 2213132 15809353
-
Hirakawa S, Kodama S, Kunstfeld R, Kajiya K, Brown LF, Detmar M (2005) VEGF-A induces tumor and sentinel lymph node lymphangiogenesis and promotes lymphatic metastasis. J Exp Med 201(7):1089-1099. doi: 10.1084/jem.20041896
-
(2005)
J Exp Med
, vol.201
, Issue.7
, pp. 1089-1099
-
-
Hirakawa, S.1
Kodama, S.2
Kunstfeld, R.3
Kajiya, K.4
Brown, L.F.5
Detmar, M.6
-
58
-
-
32244443955
-
B cell-driven lymphangiogenesis in inflamed lymph nodes enhances dendritic cell mobilization
-
10.1016/j.immuni.2006.01.003 16473832
-
Angeli V, Ginhoux F, Llodra J, Quemeneur L, Frenette PS, Skobe M, Jessberger R, Merad M, Randolph GJ (2006) B cell-driven lymphangiogenesis in inflamed lymph nodes enhances dendritic cell mobilization. Immunity 24(2):203-215. doi: 10.1016/j.immuni.2006.01.003
-
(2006)
Immunity
, vol.24
, Issue.2
, pp. 203-215
-
-
Angeli, V.1
Ginhoux, F.2
Llodra, J.3
Quemeneur, L.4
Frenette, P.S.5
Skobe, M.6
Jessberger, R.7
Merad, M.8
Randolph, G.J.9
-
59
-
-
36148936760
-
VEGF-A produced by chronically inflamed tissue induces lymphangiogenesis in draining lymph nodes
-
10.1182/blood-2007-01-066811 2200913 17625067
-
Halin C, Tobler NE, Vigl B, Brown LF, Detmar M (2007) VEGF-A produced by chronically inflamed tissue induces lymphangiogenesis in draining lymph nodes. Blood 110(9):3158-3167. doi: 10.1182/blood-2007-01-066811
-
(2007)
Blood
, vol.110
, Issue.9
, pp. 3158-3167
-
-
Halin, C.1
Tobler, N.E.2
Vigl, B.3
Brown, L.F.4
Detmar, M.5
-
60
-
-
67049167170
-
Critical role of CD11b+ macrophages and VEGF in inflammatory lymphangiogenesis, antigen clearance, and inflammation resolution
-
10.1182/blood-2008-09-176776 19346498
-
Kataru RP, Jung K, Jang C, Yang H, Schwendener RA, Baik JE, Han SH, Alitalo K, Koh GY (2009) Critical role of CD11b+ macrophages and VEGF in inflammatory lymphangiogenesis, antigen clearance, and inflammation resolution. Blood 113(22):5650-5659. doi: 10.1182/blood-2008-09-176776
-
(2009)
Blood
, vol.113
, Issue.22
, pp. 5650-5659
-
-
Kataru, R.P.1
Jung, K.2
Jang, C.3
Yang, H.4
Schwendener, R.A.5
Baik, J.E.6
Han, S.H.7
Alitalo, K.8
Koh, G.Y.9
-
61
-
-
78751688024
-
T lymphocytes negatively regulate lymph node lymphatic vessel formation
-
10.1016/j.immuni.2010.12.016 21256057
-
Kataru RP, Kim H, Jang C, Choi DK, Koh BI, Kim M, Gollamudi S, Kim YK, Lee SH, Koh GY (2011) T lymphocytes negatively regulate lymph node lymphatic vessel formation. Immunity 34(1):96-107. doi: 10.1016/j.immuni.2010.12.016
-
(2011)
Immunity
, vol.34
, Issue.1
, pp. 96-107
-
-
Kataru, R.P.1
Kim, H.2
Jang, C.3
Choi, D.K.4
Koh, B.I.5
Kim, M.6
Gollamudi, S.7
Kim, Y.K.8
Lee, S.H.9
Koh, G.Y.10
-
62
-
-
6944228960
-
VEGF-A promotes tissue repair-associated lymphatic vessel formation via VEGFR-2 and the alpha1beta1 and alpha2beta1 integrins
-
15132990
-
Hong YK, Lange-Asschenfeldt B, Velasco P, Hirakawa S, Kunstfeld R, Brown LF, Bohlen P, Senger DR, Detmar M (2004) VEGF-A promotes tissue repair-associated lymphatic vessel formation via VEGFR-2 and the alpha1beta1 and alpha2beta1 integrins. FASEB J 18(10):1111-1113
-
(2004)
FASEB J
, vol.18
, Issue.10
, pp. 1111-1113
-
-
Hong, Y.K.1
Lange-Asschenfeldt, B.2
Velasco, P.3
Hirakawa, S.4
Kunstfeld, R.5
Brown, L.F.6
Bohlen, P.7
Senger, D.R.8
Detmar, M.9
-
63
-
-
77957742772
-
Stimulation of lymphangiogenesis via VEGFR-3 inhibits chronic skin inflammation
-
10.1084/jem.20100559 2947063 20837699
-
Huggenberger R, Ullmann S, Proulx ST, Pytowski B, Alitalo K, Detmar M (2010) Stimulation of lymphangiogenesis via VEGFR-3 inhibits chronic skin inflammation. J Exp Med 207(10):2255-2269. doi: 10.1084/jem.20100559
-
(2010)
J Exp Med
, vol.207
, Issue.10
, pp. 2255-2269
-
-
Huggenberger, R.1
Ullmann, S.2
Proulx, S.T.3
Pytowski, B.4
Alitalo, K.5
Detmar, M.6
-
64
-
-
0029761644
-
Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1
-
231459 8756616
-
Forsythe JA, Jiang BH, Iyer NV, Agani F, Leung SW, Koos RD, Semenza GL (1996) Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1. Mol Cell Biol 16(9):4604-4613
-
(1996)
Mol Cell Biol
, vol.16
, Issue.9
, pp. 4604-4613
-
-
Forsythe, J.A.1
Jiang, B.H.2
Iyer, N.V.3
Agani, F.4
Leung, S.W.5
Koos, R.D.6
Semenza, G.L.7
-
65
-
-
18644382318
-
Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by angiopoietin-1
-
12361603
-
Gale NW, Thurston G, Hackett SF, Renard R, Wang Q, McClain J, Martin C, Witte C, Witte MH, Jackson D, Suri C, Campochiaro PA, Wiegand SJ, Yancopoulos GD (2002) Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by angiopoietin-1. Dev Cell 3(3):411-423
-
(2002)
Dev Cell
, vol.3
, Issue.3
, pp. 411-423
-
-
Gale, N.W.1
Thurston, G.2
Hackett, S.F.3
Renard, R.4
Wang, Q.5
McClain, J.6
Martin, C.7
Witte, C.8
Witte, M.H.9
Jackson, D.10
Suri, C.11
Campochiaro, P.A.12
Wiegand, S.J.13
Yancopoulos, G.D.14
-
66
-
-
20444414142
-
Angiopoietin-1 promotes LYVE-1-positive lymphatic vessel formation
-
10.1182/blood-2004-08-3382 15705793
-
Morisada T, Oike Y, Yamada Y, Urano T, Akao M, Kubota Y, Maekawa H, Kimura Y, Ohmura M, Miyamoto T, Nozawa S, Koh GY, Alitalo K, Suda T (2005) Angiopoietin-1 promotes LYVE-1-positive lymphatic vessel formation. Blood 105(12):4649-4656. doi: 10.1182/blood-2004-08-3382
-
(2005)
Blood
, vol.105
, Issue.12
, pp. 4649-4656
-
-
Morisada, T.1
Oike, Y.2
Yamada, Y.3
Urano, T.4
Akao, M.5
Kubota, Y.6
Maekawa, H.7
Kimura, Y.8
Ohmura, M.9
Miyamoto, T.10
Nozawa, S.11
Koh, G.Y.12
Alitalo, K.13
Suda, T.14
-
67
-
-
4143121247
-
Dose-dependent response of FGF-2 for lymphangiogenesis
-
10.1073/pnas.0404272101 511009 15289610
-
Chang LK, Garcia-Cardena G, Farnebo F, Fannon M, Chen EJ, Butterfield C, Moses MA, Mulligan RC, Folkman J, Kaipainen A (2004) Dose-dependent response of FGF-2 for lymphangiogenesis. Proc Natl Acad Sci U S A 101(32):11658-11663. doi: 10.1073/pnas.0404272101
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, Issue.32
, pp. 11658-11663
-
-
Chang, L.K.1
Garcia-Cardena, G.2
Farnebo, F.3
Fannon, M.4
Chen, E.J.5
Butterfield, C.6
Moses, M.A.7
Mulligan, R.C.8
Folkman, J.9
Kaipainen, A.10
-
68
-
-
31944443701
-
Prox1 promotes lineage-specific expression of fibroblast growth factor (FGF) receptor-3 in lymphatic endothelium: A role for FGF signaling in lymphangiogenesis
-
10.1091/mbc.E05-04-0368 1356570 16291864
-
Shin JW, Min M, Larrieu-Lahargue F, Canron X, Kunstfeld R, Nguyen L, Henderson JE, Bikfalvi A, Detmar M, Hong YK (2006) Prox1 promotes lineage-specific expression of fibroblast growth factor (FGF) receptor-3 in lymphatic endothelium: a role for FGF signaling in lymphangiogenesis. Mol Biol Cell 17(2):576-584. doi: 10.1091/mbc.E05-04-0368
-
(2006)
Mol Biol Cell
, vol.17
, Issue.2
, pp. 576-584
-
-
Shin, J.W.1
Min, M.2
Larrieu-Lahargue, F.3
Canron, X.4
Kunstfeld, R.5
Nguyen, L.6
Henderson, J.E.7
Bikfalvi, A.8
Detmar, M.9
Hong, Y.K.10
-
69
-
-
30544452034
-
Hepatocyte growth factor promotes lymphatic vessel formation and function
-
10.1038/sj.emboj.7600763 1187946 16052207
-
Kajiya K, Hirakawa S, Ma B, Drinnenberg I, Detmar M (2005) Hepatocyte growth factor promotes lymphatic vessel formation and function. EMBO J 24(16):2885-2895. doi: 10.1038/sj.emboj.7600763
-
(2005)
EMBO J
, vol.24
, Issue.16
, pp. 2885-2895
-
-
Kajiya, K.1
Hirakawa, S.2
Ma, B.3
Drinnenberg, I.4
Detmar, M.5
-
70
-
-
5444266254
-
PDGF-BB induces intratumoral lymphangiogenesis and promotes lymphatic metastasis
-
10.1016/j.ccr.2004.08.034 15488757
-
Cao R, Bjorndahl MA, Religa P, Clasper S, Garvin S, Galter D, Meister B, Ikomi F, Tritsaris K, Dissing S, Ohhashi T, Jackson DG, Cao Y (2004) PDGF-BB induces intratumoral lymphangiogenesis and promotes lymphatic metastasis. Cancer Cell 6(4):333-345. doi: 10.1016/j.ccr.2004.08.034
-
(2004)
Cancer Cell
, vol.6
, Issue.4
, pp. 333-345
-
-
Cao, R.1
Bjorndahl, M.A.2
Religa, P.3
Clasper, S.4
Garvin, S.5
Galter, D.6
Meister, B.7
Ikomi, F.8
Tritsaris, K.9
Dissing, S.10
Ohhashi, T.11
Jackson, D.G.12
Cao, Y.13
-
71
-
-
27344431724
-
Insulin-like growth factors 1 and 2 induce lymphangiogenesis in vivo
-
10.1073/pnas.0507865102 1266150 16230630
-
Bjorndahl M, Cao R, Nissen LJ, Clasper S, Johnson LA, Xue Y, Zhou Z, Jackson D, Hansen AJ, Cao Y (2005) Insulin-like growth factors 1 and 2 induce lymphangiogenesis in vivo. Proc Natl Acad Sci U S A 102(43):15593-15598. doi: 10.1073/pnas.0507865102
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, Issue.43
, pp. 15593-15598
-
-
Bjorndahl, M.1
Cao, R.2
Nissen, L.J.3
Clasper, S.4
Johnson, L.A.5
Xue, Y.6
Zhou, Z.7
Jackson, D.8
Hansen, A.J.9
Cao, Y.10
-
72
-
-
63849230366
-
Toll-like receptor 4 in lymphatic endothelial cells contributes to LPS-induced lymphangiogenesis by chemotactic recruitment of macrophages
-
10.1182/blood-2008-07-166934 19098273
-
Kang S, Lee SP, Kim KE, Kim HZ, Memet S, Koh GY (2009) Toll-like receptor 4 in lymphatic endothelial cells contributes to LPS-induced lymphangiogenesis by chemotactic recruitment of macrophages. Blood 113(11):2605-2613. doi: 10.1182/blood-2008-07-166934
-
(2009)
Blood
, vol.113
, Issue.11
, pp. 2605-2613
-
-
Kang, S.1
Lee, S.P.2
Kim, K.E.3
Kim, H.Z.4
Memet, S.5
Koh, G.Y.6
-
73
-
-
73549105244
-
Role of CD11b+ macrophages in intraperitoneal lipopolysaccharide-induced aberrant lymphangiogenesis and lymphatic function in the diaphragm
-
10.2353/ajpath.2009.090133 2751568 19762711
-
Kim KE, Koh YJ, Jeon BH, Jang C, Han J, Kataru RP, Schwendener RA, Kim JM, Koh GY (2009) Role of CD11b+ macrophages in intraperitoneal lipopolysaccharide-induced aberrant lymphangiogenesis and lymphatic function in the diaphragm. Am J Pathol 175(4):1733-1745. doi: 10.2353/ajpath.2009.090133
-
(2009)
Am J Pathol
, vol.175
, Issue.4
, pp. 1733-1745
-
-
Kim, K.E.1
Koh, Y.J.2
Jeon, B.H.3
Jang, C.4
Han, J.5
Kataru, R.P.6
Schwendener, R.A.7
Kim, J.M.8
Koh, G.Y.9
-
74
-
-
84875130753
-
Transgenic overexpression of interleukin-1beta induces persistent lymphangiogenesis but not angiogenesis in mouse airways
-
10.1016/j.ajpath.2012.12.003 3620402 23391392
-
Baluk P, Hogmalm A, Bry M, Alitalo K, Bry K, McDonald DM (2013) Transgenic overexpression of interleukin-1beta induces persistent lymphangiogenesis but not angiogenesis in mouse airways. Am J Pathol 182(4):1434-1447. doi: 10.1016/j.ajpath.2012.12.003
-
(2013)
Am J Pathol
, vol.182
, Issue.4
, pp. 1434-1447
-
-
Baluk, P.1
Hogmalm, A.2
Bry, M.3
Alitalo, K.4
Bry, K.5
McDonald, D.M.6
-
75
-
-
56049087039
-
Role of macrophages in inflammatory lymphangiogenesis: Enhanced production of vascular endothelial growth factor C and D through NF-kappaB activation
-
10.1016/j.bbrc.2008.10.077 18951870
-
Watari K, Nakao S, Fotovati A, Basaki Y, Hosoi F, Bereczky B, Higuchi R, Miyamoto T, Kuwano M, Ono M (2008) Role of macrophages in inflammatory lymphangiogenesis: enhanced production of vascular endothelial growth factor C and D through NF-kappaB activation. Biochem Biophys Res Commun 377(3):826-831. doi: 10.1016/j.bbrc.2008.10.077
-
(2008)
Biochem Biophys Res Commun
, vol.377
, Issue.3
, pp. 826-831
-
-
Watari, K.1
Nakao, S.2
Fotovati, A.3
Basaki, Y.4
Hosoi, F.5
Bereczky, B.6
Higuchi, R.7
Miyamoto, T.8
Kuwano, M.9
Ono, M.10
-
76
-
-
66049154097
-
M-CSF inhibition selectively targets pathological angiogenesis and lymphangiogenesis
-
10.1084/jem.20081605 2715025 19398755
-
Kubota Y, Takubo K, Shimizu T, Ohno H, Kishi K, Shibuya M, Saya H, Suda T (2009) M-CSF inhibition selectively targets pathological angiogenesis and lymphangiogenesis. J Exp Med 206(5):1089-1102. doi: 10.1084/jem.20081605
-
(2009)
J Exp Med
, vol.206
, Issue.5
, pp. 1089-1102
-
-
Kubota, Y.1
Takubo, K.2
Shimizu, T.3
Ohno, H.4
Kishi, K.5
Shibuya, M.6
Saya, H.7
Suda, T.8
-
77
-
-
33846219169
-
Tumor necrosis factor-alpha induces vascular endothelial growth factor-C expression in rheumatoid synoviocytes
-
17216674
-
Cha HS, Bae EK, Koh JH, Chai JY, Jeon CH, Ahn KS, Kim J, Koh EM (2007) Tumor necrosis factor-alpha induces vascular endothelial growth factor-C expression in rheumatoid synoviocytes. J Rheumatol 34(1):16-19
-
(2007)
J Rheumatol
, vol.34
, Issue.1
, pp. 16-19
-
-
Cha, H.S.1
Bae, E.K.2
Koh, J.H.3
Chai, J.Y.4
Jeon, C.H.5
Ahn, K.S.6
Kim, J.7
Koh, E.M.8
-
78
-
-
77957571628
-
Differential cytokine responses in human and mouse lymphatic endothelial cells to cytokines in vitro
-
10.1089/lrb 3357074 20863268 2010.0004
-
Chaitanya GV, Franks SE, Cromer W, Wells SR, Bienkowska M, Jennings MH, Ruddell A, Ando T, Wang Y, Gu Y, Sapp M, Mathis JM, Jordan PA, Minagar A, Alexander JS (2010) Differential cytokine responses in human and mouse lymphatic endothelial cells to cytokines in vitro. Lymphat Res Biol 8(3):155-164. doi: 10.1089/lrb 2010.0004
-
(2010)
Lymphat Res Biol
, vol.8
, Issue.3
, pp. 155-164
-
-
Chaitanya, G.V.1
Franks, S.E.2
Cromer, W.3
Wells, S.R.4
Bienkowska, M.5
Jennings, M.H.6
Ruddell, A.7
Ando, T.8
Wang, Y.9
Gu, Y.10
Sapp, M.11
Mathis, J.M.12
Jordan, P.A.13
Minagar, A.14
Alexander, J.S.15
-
79
-
-
34447522311
-
Vascular endothelial growth factor-A mediates ultraviolet B-induced impairment of lymphatic vessel function
-
10.2353/ajpath.2006.060197 1780190 17003502
-
Kajiya K, Hirakawa S, Detmar M (2006) Vascular endothelial growth factor-A mediates ultraviolet B-induced impairment of lymphatic vessel function. Am J Pathol 169(4):1496-1503. doi: 10.2353/ajpath.2006.060197
-
(2006)
Am J Pathol
, vol.169
, Issue.4
, pp. 1496-1503
-
-
Kajiya, K.1
Hirakawa, S.2
Detmar, M.3
-
80
-
-
77954227279
-
Near-infrared lymphatic imaging demonstrates the dynamics of lymph flow and lymphangiogenesis during the acute versus chronic phases of arthritis in mice
-
10.1002/art.27464 2902657 20309866
-
Zhou Q, Wood R, Schwarz EM, Wang YJ, Xing L (2010) Near-infrared lymphatic imaging demonstrates the dynamics of lymph flow and lymphangiogenesis during the acute versus chronic phases of arthritis in mice. Arthritis Rheum 62(7):1881-1889. doi: 10.1002/art.27464
-
(2010)
Arthritis Rheum
, vol.62
, Issue.7
, pp. 1881-1889
-
-
Zhou, Q.1
Wood, R.2
Schwarz, E.M.3
Wang, Y.J.4
Xing, L.5
-
81
-
-
79961103686
-
Vascular endothelial growth factor C attenuates joint damage in chronic inflammatory arthritis by accelerating local lymphatic drainage in mice
-
10.1002/art.30421 3149728 21538325
-
Zhou Q, Guo R, Wood R, Boyce BF, Liang Q, Wang YJ, Schwarz EM, Xing L (2011) Vascular endothelial growth factor C attenuates joint damage in chronic inflammatory arthritis by accelerating local lymphatic drainage in mice. Arthritis Rheum 63(8):2318-2328. doi: 10.1002/art.30421
-
(2011)
Arthritis Rheum
, vol.63
, Issue.8
, pp. 2318-2328
-
-
Zhou, Q.1
Guo, R.2
Wood, R.3
Boyce, B.F.4
Liang, Q.5
Wang, Y.J.6
Schwarz, E.M.7
Xing, L.8
-
82
-
-
69449095482
-
Inhibition of lymphangiogenesis and lymphatic drainage via vascular endothelial growth factor receptor 3 blockade increases the severity of inflammation in a mouse model of chronic inflammatory arthritis
-
10.1002/art.24764 2810533 19714652
-
Guo R, Zhou Q, Proulx ST, Wood R, Ji RC, Ritchlin CT, Pytowski B, Zhu Z, Wang YJ, Schwarz EM, Xing L (2009) Inhibition of lymphangiogenesis and lymphatic drainage via vascular endothelial growth factor receptor 3 blockade increases the severity of inflammation in a mouse model of chronic inflammatory arthritis. Arthritis Rheum 60(9):2666-2676. doi: 10.1002/art.24764
-
(2009)
Arthritis Rheum
, vol.60
, Issue.9
, pp. 2666-2676
-
-
Guo, R.1
Zhou, Q.2
Proulx, S.T.3
Wood, R.4
Ji, R.C.5
Ritchlin, C.T.6
Pytowski, B.7
Zhu, Z.8
Wang, Y.J.9
Schwarz, E.M.10
Xing, L.11
-
83
-
-
0038644624
-
Transgenic delivery of VEGF to mouse skin leads to an inflammatory condition resembling human psoriasis
-
10.1182/blood-2002-12-3793 12649136
-
Xia YP, Li B, Hylton D, Detmar M, Yancopoulos GD, Rudge JS (2003) Transgenic delivery of VEGF to mouse skin leads to an inflammatory condition resembling human psoriasis. Blood 102(1):161-168. doi: 10.1182/blood-2002-12- 3793
-
(2003)
Blood
, vol.102
, Issue.1
, pp. 161-168
-
-
Xia, Y.P.1
Li, B.2
Hylton, D.3
Detmar, M.4
Yancopoulos, G.D.5
Rudge, J.S.6
-
84
-
-
15244351683
-
Vascular endothelial growth factor promotes sensitivity to ultraviolet B-induced cutaneous photodamage
-
10.1182/blood-2004-06-2435 15550485
-
Hirakawa S, Fujii S, Kajiya K, Yano K, Detmar M (2005) Vascular endothelial growth factor promotes sensitivity to ultraviolet B-induced cutaneous photodamage. Blood 105(6):2392-2399. doi: 10.1182/blood-2004-06-2435
-
(2005)
Blood
, vol.105
, Issue.6
, pp. 2392-2399
-
-
Hirakawa, S.1
Fujii, S.2
Kajiya, K.3
Yano, K.4
Detmar, M.5
-
85
-
-
65049085803
-
Activation of the VEGFR-3 pathway by VEGF-C attenuates UVB-induced edema formation and skin inflammation by promoting lymphangiogenesis
-
10.1038/jid.2008.351 19005491
-
Kajiya K, Sawane M, Huggenberger R, Detmar M (2009) Activation of the VEGFR-3 pathway by VEGF-C attenuates UVB-induced edema formation and skin inflammation by promoting lymphangiogenesis. J Invest Dermatol 129(5):1292-1298. doi: 10.1038/jid.2008.351
-
(2009)
J Invest Dermatol
, vol.129
, Issue.5
, pp. 1292-1298
-
-
Kajiya, K.1
Sawane, M.2
Huggenberger, R.3
Detmar, M.4
-
86
-
-
33646252033
-
An important role of lymphatic vessels in the control of UVB-induced edema formation and inflammation
-
10.1038/sj.jid.5700126 16470183
-
Kajiya K, Detmar M (2006) An important role of lymphatic vessels in the control of UVB-induced edema formation and inflammation. J Invest Dermatol 126(4):919-921. doi: 10.1038/sj.jid.5700126
-
(2006)
J Invest Dermatol
, vol.126
, Issue.4
, pp. 919-921
-
-
Kajiya, K.1
Detmar, M.2
-
87
-
-
84884609221
-
Blockade of VEGF receptor-3 aggravates inflammatory bowel disease and lymphatic vessel enlargement
-
23835443
-
Jurisic G, Sundberg JP, Detmar M (2013) Blockade of VEGF receptor-3 aggravates inflammatory bowel disease and lymphatic vessel enlargement. Inflamm Bowel Dis 19:1983-1989
-
(2013)
Inflamm Bowel Dis
, vol.19
, pp. 1983-1989
-
-
Jurisic, G.1
Sundberg, J.P.2
Detmar, M.3
-
88
-
-
84874273601
-
Lymphatic endothelial cells - Key players in regulation of tolerance and immunity
-
10.3389/fimmu.2012.00305 3460259 23060883
-
Tewalt EF, Cohen JN, Rouhani SJ, Engelhard VH (2012) Lymphatic endothelial cells - key players in regulation of tolerance and immunity. Front Immunol 3:305. doi: 10.3389/fimmu.2012.00305
-
(2012)
Front Immunol
, vol.3
, pp. 305
-
-
Tewalt, E.F.1
Cohen, J.N.2
Rouhani, S.J.3
Engelhard, V.H.4
-
89
-
-
84879709783
-
An analysis of the function and expression of D6 on lymphatic endothelial cells
-
10.1182/blood-2012-04-425314 23479571
-
McKimmie CS, Singh MD, Hewit K, Lopez-Franco O, Le Brocq M, Rose-John S, Lee KM, Baker AH, Wheat R, Blackbourn DJ, Nibbs RJ, Graham GJ (2013) An analysis of the function and expression of D6 on lymphatic endothelial cells. Blood. doi: 10.1182/blood-2012-04-425314
-
(2013)
Blood
-
-
McKimmie, C.S.1
Singh, M.D.2
Hewit, K.3
Lopez-Franco, O.4
Le Brocq, M.5
Rose-John, S.6
Lee, K.M.7
Baker, A.H.8
Wheat, R.9
Blackbourn, D.J.10
Nibbs, R.J.11
Graham, G.J.12
-
90
-
-
77149126406
-
The lymphatic system controls intestinal inflammation and inflammation-associated colon cancer through the chemokine decoy receptor D6
-
10.1136/gut.2009.183772 19846409
-
Vetrano S, Borroni EM, Sarukhan A, Savino B, Bonecchi R, Correale C, Arena V, Fantini M, Roncalli M, Malesci A, Mantovani A, Locati M, Danese S (2010) The lymphatic system controls intestinal inflammation and inflammation-associated colon cancer through the chemokine decoy receptor D6. Gut 59(2):197-206. doi: 10.1136/gut.2009.183772
-
(2010)
Gut
, vol.59
, Issue.2
, pp. 197-206
-
-
Vetrano, S.1
Borroni, E.M.2
Sarukhan, A.3
Savino, B.4
Bonecchi, R.5
Correale, C.6
Arena, V.7
Fantini, M.8
Roncalli, M.9
Malesci, A.10
Mantovani, A.11
Locati, M.12
Danese, S.13
-
91
-
-
84859385704
-
Sphingosine-1-phosphate and lymphocyte egress from lymphoid organs
-
10.1146/annurev-immunol-020711-075011 22149932
-
Cyster JG, Schwab SR (2012) Sphingosine-1-phosphate and lymphocyte egress from lymphoid organs. Annu Rev Immunol 30:69-94. doi: 10.1146/annurev-immunol- 020711-075011
-
(2012)
Annu Rev Immunol
, vol.30
, pp. 69-94
-
-
Cyster, J.G.1
Schwab, S.R.2
-
92
-
-
84860320665
-
Expansion of cortical and medullary sinuses restrains lymph node hypertrophy during prolonged inflammation
-
10.4049/jimmunol.1101854 22430738
-
Tan KW, Yeo KP, Wong FH, Lim HY, Khoo KL, Abastado JP, Angeli V (2012) Expansion of cortical and medullary sinuses restrains lymph node hypertrophy during prolonged inflammation. J Immunol 188(8):4065-4080. doi: 10.4049/jimmunol.1101854
-
(2012)
J Immunol
, vol.188
, Issue.8
, pp. 4065-4080
-
-
Tan, K.W.1
Yeo, K.P.2
Wong, F.H.3
Lim, H.Y.4
Khoo, K.L.5
Abastado, J.P.6
Angeli, V.7
-
93
-
-
81055145081
-
Regulation of T cell priming by lymphoid stroma
-
10.1371/journal.pone.0026138 3215700 22110583
-
Khan O, Headley M, Gerard A, Wei W, Liu L, Krummel MF (2011) Regulation of T cell priming by lymphoid stroma. PLoS ONE 6(11):e26138. doi: 10.1371/journal.pone.0026138
-
(2011)
PLoS ONE
, vol.6
, Issue.11
, pp. 26138
-
-
Khan, O.1
Headley, M.2
Gerard, A.3
Wei, W.4
Liu, L.5
Krummel, M.F.6
-
94
-
-
80054918372
-
Regulated release of nitric oxide by nonhematopoietic stroma controls expansion of the activated T cell pool in lymph nodes
-
10.1038/ni.2112 3457791 21926986
-
Lukacs-Kornek V, Malhotra D, Fletcher AL, Acton SE, Elpek KG, Tayalia P, Collier AR, Turley SJ (2011) Regulated release of nitric oxide by nonhematopoietic stroma controls expansion of the activated T cell pool in lymph nodes. Nat Immunol 12(11):1096-1104. doi: 10.1038/ni.2112
-
(2011)
Nat Immunol
, vol.12
, Issue.11
, pp. 1096-1104
-
-
Lukacs-Kornek, V.1
Malhotra, D.2
Fletcher, A.L.3
Acton, S.E.4
Elpek, K.G.5
Tayalia, P.6
Collier, A.R.7
Turley, S.J.8
-
95
-
-
68149124237
-
Inflamed lymphatic endothelium suppresses dendritic cell maturation and function via Mac-1/ICAM-1-dependent mechanism
-
10.4049/jimmunol.0802167 19587009
-
Podgrabinska S, Kamalu O, Mayer L, Shimaoka M, Snoeck H, Randolph GJ, Skobe M (2009) Inflamed lymphatic endothelium suppresses dendritic cell maturation and function via Mac-1/ICAM-1-dependent mechanism. J Immunol 183(3):1767-1779. doi: 10.4049/jimmunol.0802167
-
(2009)
J Immunol
, vol.183
, Issue.3
, pp. 1767-1779
-
-
Podgrabinska, S.1
Kamalu, O.2
Mayer, L.3
Shimaoka, M.4
Snoeck, H.5
Randolph, G.J.6
Skobe, M.7
-
96
-
-
77951069509
-
Lymph node-resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation
-
10.1084/jem.20092465 2856027 20308365
-
Cohen JN, Guidi CJ, Tewalt EF, Qiao H, Rouhani SJ, Ruddell A, Farr AG, Tung KS, Engelhard VH (2010) Lymph node-resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation. J Exp Med 207(4):681-688. doi: 10.1084/jem.20092465
-
(2010)
J Exp Med
, vol.207
, Issue.4
, pp. 681-688
-
-
Cohen, J.N.1
Guidi, C.J.2
Tewalt, E.F.3
Qiao, H.4
Rouhani, S.J.5
Ruddell, A.6
Farr, A.G.7
Tung, K.S.8
Engelhard, V.H.9
-
97
-
-
77951074210
-
Lymph node fibroblastic reticular cells directly present peripheral tissue antigen under steady-state and inflammatory conditions
-
10.1084/jem.20092642 2856033 20308362
-
Fletcher AL, Lukacs-Kornek V, Reynoso ED, Pinner SE, Bellemare-Pelletier A, Curry MS, Collier AR, Boyd RL, Turley SJ (2010) Lymph node fibroblastic reticular cells directly present peripheral tissue antigen under steady-state and inflammatory conditions. J Exp Med 207(4):689-697. doi: 10.1084/jem.20092642
-
(2010)
J Exp Med
, vol.207
, Issue.4
, pp. 689-697
-
-
Fletcher, A.L.1
Lukacs-Kornek, V.2
Reynoso, E.D.3
Pinner, S.E.4
Bellemare-Pelletier, A.5
Curry, M.S.6
Collier, A.R.7
Boyd, R.L.8
Turley, S.J.9
-
98
-
-
84870729573
-
Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells
-
10.1182/blood-2012-04-427013 3520619 22993390
-
Tewalt EF, Cohen JN, Rouhani SJ, Guidi CJ, Qiao H, Fahl SP, Conaway MR, Bender TP, Tung KS, Vella AT, Adler AJ, Chen L, Engelhard VH (2012) Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells. Blood 120(24):4772-4782. doi: 10.1182/blood-2012-04-427013
-
(2012)
Blood
, vol.120
, Issue.24
, pp. 4772-4782
-
-
Tewalt, E.F.1
Cohen, J.N.2
Rouhani, S.J.3
Guidi, C.J.4
Qiao, H.5
Fahl, S.P.6
Conaway, M.R.7
Bender, T.P.8
Tung, K.S.9
Vella, A.T.10
Adler, A.J.11
Chen, L.12
Engelhard, V.H.13
-
99
-
-
84867748641
-
Interaction of tumor cells and lymphatic vessels in cancer progression
-
10.1038/onc.2011.602 22179834
-
Alitalo A, Detmar M (2012) Interaction of tumor cells and lymphatic vessels in cancer progression. Oncogene 31(42):4499-4508. doi: 10.1038/onc.2011.602
-
(2012)
Oncogene
, vol.31
, Issue.42
, pp. 4499-4508
-
-
Alitalo, A.1
Detmar, M.2
-
100
-
-
84894404797
-
Therapeutic lymphangiogenesis with implantation of adipose-derived regenerative cells
-
10.1161/JAHA.112.000877 3487362 23130156
-
Shimizu Y, Shibata R, Shintani S, Ishii M, Murohara T (2012) Therapeutic lymphangiogenesis with implantation of adipose-derived regenerative cells. J Am Heart Assoc 1(4):e000877. doi: 10.1161/JAHA.112.000877
-
(2012)
J Am Heart Assoc
, vol.1
, Issue.4
, pp. 000877
-
-
Shimizu, Y.1
Shibata, R.2
Shintani, S.3
Ishii, M.4
Murohara, T.5
-
101
-
-
84871615440
-
Interleukin-8 reduces post-surgical lymphedema formation by promoting lymphatic vessel regeneration
-
10.1007/s10456-012-9297-6 22945845
-
Choi I, Lee YS, Chung HK, Choi D, Ecoiffier T, Lee HN, Kim KE, Lee S, Park EK, Maeng YS, Kim NY, Ladner RD, Petasis NA, Koh CJ, Chen L, Lenz HJ, Hong YK (2013) Interleukin-8 reduces post-surgical lymphedema formation by promoting lymphatic vessel regeneration. Angiogenesis 16(1):29-44. doi: 10.1007/s10456-012-9297-6
-
(2013)
Angiogenesis
, vol.16
, Issue.1
, pp. 29-44
-
-
Choi, I.1
Lee, Y.S.2
Chung, H.K.3
Choi, D.4
Ecoiffier, T.5
Lee, H.N.6
Kim, K.E.7
Lee, S.8
Park, E.K.9
Maeng, Y.S.10
Kim, N.Y.11
Ladner, R.D.12
Petasis, N.A.13
Koh, C.J.14
Chen, L.15
Lenz, H.J.16
Hong, Y.K.17
-
102
-
-
84863230033
-
9-cis retinoic acid promotes lymphangiogenesis and enhances lymphatic vessel regeneration: Therapeutic implications of 9-cis retinoic acid for secondary lymphedema
-
10.1161/CIRCULATIONAHA.111.030296 3327127 22275501
-
Choi I, Lee S, Kyoung Chung H, Suk Lee Y, Eui Kim K, Choi D, Park EK, Yang D, Ecoiffier T, Monahan J, Chen W, Aguilar B, Lee HN, Yoo J, Koh CJ, Chen L, Wong AK, Hong YK (2012) 9-cis retinoic acid promotes lymphangiogenesis and enhances lymphatic vessel regeneration: therapeutic implications of 9-cis retinoic acid for secondary lymphedema. Circulation 125(7):872-882. doi: 10.1161/CIRCULATIONAHA.111.030296
-
(2012)
Circulation
, vol.125
, Issue.7
, pp. 872-882
-
-
Choi, I.1
Lee, S.2
Kyoung Chung, H.3
Suk Lee, Y.4
Eui Kim, K.5
Choi, D.6
Park, E.K.7
Yang, D.8
Ecoiffier, T.9
Monahan, J.10
Chen, W.11
Aguilar, B.12
Lee, H.N.13
Yoo, J.14
Koh, C.J.15
Chen, L.16
Wong, A.K.17
Hong, Y.K.18
-
103
-
-
78449232572
-
A role for all-trans-retinoic acid in the early steps of lymphatic vasculature development
-
2997449 21099229
-
Marino D, Dabouras V, Brändli AW, Detmar M (2011) A role for all-trans-retinoic acid in the early steps of lymphatic vasculature development. J Vasc Res 48:236-251
-
(2011)
J Vasc Res
, vol.48
, pp. 236-251
-
-
Marino, D.1
Dabouras, V.2
Brändli, A.W.3
Detmar, M.4
-
104
-
-
35948974298
-
Inhibition of cyclooxygenase-2 suppresses lymph node metastasis via reduction of lymphangiogenesis
-
10.1158/0008-5472.CAN-07-2366 17974958
-
Iwata C, Kano MR, Komuro A, Oka M, Kiyono K, Johansson E, Morishita Y, Yashiro M, Hirakawa K, Kaminishi M, Miyazono K (2007) Inhibition of cyclooxygenase-2 suppresses lymph node metastasis via reduction of lymphangiogenesis. Cancer Res 67(21):10181-10189. doi: 10.1158/0008-5472.CAN-07- 2366
-
(2007)
Cancer Res
, vol.67
, Issue.21
, pp. 10181-10189
-
-
Iwata, C.1
Kano, M.R.2
Komuro, A.3
Oka, M.4
Kiyono, K.5
Johansson, E.6
Morishita, Y.7
Yashiro, M.8
Hirakawa, K.9
Kaminishi, M.10
Miyazono, K.11
-
105
-
-
80052283479
-
Role of COX-2 in lymphangiogenesis and restoration of lymphatic flow in secondary lymphedema
-
10.1038/labinvest.2011.84 21577211
-
Kashiwagi S, Hosono K, Suzuki T, Takeda A, Uchinuma E, Majima M (2011) Role of COX-2 in lymphangiogenesis and restoration of lymphatic flow in secondary lymphedema. Lab Invest 91(9):1314-1325. doi: 10.1038/labinvest.2011.84
-
(2011)
Lab Invest
, vol.91
, Issue.9
, pp. 1314-1325
-
-
Kashiwagi, S.1
Hosono, K.2
Suzuki, T.3
Takeda, A.4
Uchinuma, E.5
Majima, M.6
-
106
-
-
84863011445
-
VEGF-D promotes tumor metastasis by regulating prostaglandins produced by the collecting lymphatic endothelium
-
10.1016/j.ccr.2011.12.026 22340592
-
Karnezis T, Shayan R, Caesar C, Roufail S, Harris NC, Ardipradja K, Zhang YF, Williams SP, Farnsworth RH, Chai MG, Rupasinghe TW, Tull DL, Baldwin ME, Sloan EK, Fox SB, Achen MG, Stacker SA (2012) VEGF-D promotes tumor metastasis by regulating prostaglandins produced by the collecting lymphatic endothelium. Cancer Cell 21(2):181-195. doi: 10.1016/j.ccr.2011.12.026
-
(2012)
Cancer Cell
, vol.21
, Issue.2
, pp. 181-195
-
-
Karnezis, T.1
Shayan, R.2
Caesar, C.3
Roufail, S.4
Harris, N.C.5
Ardipradja, K.6
Zhang, Y.F.7
Williams, S.P.8
Farnsworth, R.H.9
Chai, M.G.10
Rupasinghe, T.W.11
Tull, D.L.12
Baldwin, M.E.13
Sloan, E.K.14
Fox, S.B.15
Achen, M.G.16
Stacker, S.A.17
-
107
-
-
77749285699
-
Steroid-resistant lymphatic remodeling in chronically inflamed mouse airways
-
10.2353/ajpath.2010.090909 2832171 20093490
-
Yao LC, Baluk P, Feng J, McDonald DM (2010) Steroid-resistant lymphatic remodeling in chronically inflamed mouse airways. Am J Pathol 176(3):1525-1541. doi: 10.2353/ajpath.2010.090909
-
(2010)
Am J Pathol
, vol.176
, Issue.3
, pp. 1525-1541
-
-
Yao, L.C.1
Baluk, P.2
Feng, J.3
McDonald, D.M.4
-
108
-
-
81355148829
-
Glucocorticoids suppress corneal lymphangiogenesis
-
10.1097/ICO.0b013e318213f39f 21955630
-
Steele MM, Kelley PM, Schieler AM, Tempero RM (2011) Glucocorticoids suppress corneal lymphangiogenesis. Cornea 30(12):1442-1447. doi: 10.1097/ICO.0b013e318213f39f
-
(2011)
Cornea
, vol.30
, Issue.12
, pp. 1442-1447
-
-
Steele, M.M.1
Kelley, P.M.2
Schieler, A.M.3
Tempero, R.M.4
-
109
-
-
79953848284
-
Suppression of inflammatory corneal lymphangiogenesis by application of topical corticosteroids
-
10.1001/archophthalmol.2011.42 21482870
-
Hos D, Saban DR, Bock F, Regenfuss B, Onderka J, Masli S, Cursiefen C (2011) Suppression of inflammatory corneal lymphangiogenesis by application of topical corticosteroids. Arch Ophthalmol 129(4):445-452. doi: 10.1001/archophthalmol.2011.42
-
(2011)
Arch Ophthalmol
, vol.129
, Issue.4
, pp. 445-452
-
-
Hos, D.1
Saban, D.R.2
Bock, F.3
Regenfuss, B.4
Onderka, J.5
Masli, S.6
Cursiefen, C.7
-
110
-
-
33750716047
-
Glucocorticoids suppress tumor lymphangiogenesis of prostate cancer cells
-
10.1158/1078-0432.CCR-06-0749 17062674
-
Yano A, Fujii Y, Iwai A, Kawakami S, Kageyama Y, Kihara K (2006) Glucocorticoids suppress tumor lymphangiogenesis of prostate cancer cells. Clin Cancer Res 12(20 Pt 1):6012-6017. doi: 10.1158/1078-0432.CCR-06-0749
-
(2006)
Clin Cancer Res
, vol.12
, Issue.20 PART 1
, pp. 6012-6017
-
-
Yano, A.1
Fujii, Y.2
Iwai, A.3
Kawakami, S.4
Kageyama, Y.5
Kihara, K.6
-
111
-
-
84862768738
-
Efficacy of topical blockade of interleukin-1 in experimental dry eye disease
-
10.1016/j.ajo.2012.01.034 3378826 22541929
-
Okanobo A, Chauhan SK, Dastjerdi MH, Kodati S, Dana R (2012) Efficacy of topical blockade of interleukin-1 in experimental dry eye disease. Am J Ophthalmol 154(1):63-71. doi: 10.1016/j.ajo.2012.01.034
-
(2012)
Am J Ophthalmol
, vol.154
, Issue.1
, pp. 63-71
-
-
Okanobo, A.1
Chauhan, S.K.2
Dastjerdi, M.H.3
Kodati, S.4
Dana, R.5
-
112
-
-
79960905472
-
Interleukin-6 signalling regulates vascular endothelial growth factor-C synthesis and lymphangiogenesis in human oral squamous cell carcinoma
-
10.1002/path.2935 21710490
-
Shinriki S, Jono H, Ueda M, Ota K, Ota T, Sueyoshi T, Oike Y, Ibusuki M, Hiraki A, Nakayama H, Shinohara M, Ando Y (2011) Interleukin-6 signalling regulates vascular endothelial growth factor-C synthesis and lymphangiogenesis in human oral squamous cell carcinoma. J Pathol 225(1):142-150. doi: 10.1002/path.2935
-
(2011)
J Pathol
, vol.225
, Issue.1
, pp. 142-150
-
-
Shinriki, S.1
Jono, H.2
Ueda, M.3
Ota, K.4
Ota, T.5
Sueyoshi, T.6
Oike, Y.7
Ibusuki, M.8
Hiraki, A.9
Nakayama, H.10
Shinohara, M.11
Ando, Y.12
-
113
-
-
54349099539
-
Tumour necrosis factor blockade increases lymphangiogenesis in murine and human arthritic joints
-
10.1136/ard.2007.083394 18174217
-
Polzer K, Baeten D, Soleiman A, Distler J, Gerlag DM, Tak PP, Schett G, Zwerina J (2008) Tumour necrosis factor blockade increases lymphangiogenesis in murine and human arthritic joints. Ann Rheum Dis 67(11):1610-1616. doi: 10.1136/ard.2007.083394
-
(2008)
Ann Rheum Dis
, vol.67
, Issue.11
, pp. 1610-1616
-
-
Polzer, K.1
Baeten, D.2
Soleiman, A.3
Distler, J.4
Gerlag, D.M.5
Tak, P.P.6
Schett, G.7
Zwerina, J.8
-
114
-
-
84867055688
-
Phenotype-based high-content chemical library screening identifies statins as inhibitors of in vivo lymphangiogenesis
-
10.1073/pnas.1206036109 3479568 22949700
-
Schulz MM, Reisen F, Zgraggen S, Fischer S, Yuen D, Kang GJ, Chen L, Schneider G, Detmar M (2012) Phenotype-based high-content chemical library screening identifies statins as inhibitors of in vivo lymphangiogenesis. Proc Natl Acad Sci U S A 109(40):E2665-E2674. doi: 10.1073/pnas.1206036109
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, Issue.40
-
-
Schulz, M.M.1
Reisen, F.2
Zgraggen, S.3
Fischer, S.4
Yuen, D.5
Kang, G.J.6
Chen, L.7
Schneider, G.8
Detmar, M.9
-
115
-
-
70349658714
-
TNF-alpha drives remodeling of blood vessels and lymphatics in sustained airway inflammation in mice
-
10.1172/JCI37626 2752063 19759514
-
Baluk P, Yao LC, Feng J, Romano T, Jung SS, Schreiter JL, Yan L, Shealy DJ, McDonald DM (2009) TNF-alpha drives remodeling of blood vessels and lymphatics in sustained airway inflammation in mice. J Clin Invest 119(10):2954-2964. doi: 10.1172/JCI37626
-
(2009)
J Clin Invest
, vol.119
, Issue.10
, pp. 2954-2964
-
-
Baluk, P.1
Yao, L.C.2
Feng, J.3
Romano, T.4
Jung, S.S.5
Schreiter, J.L.6
Yan, L.7
Shealy, D.J.8
McDonald, D.M.9
-
116
-
-
79951777800
-
Human cytomegalovirus productively infects lymphatic endothelial cells and induces a secretome that promotes angiogenesis and lymphangiogenesis through interleukin-6 and granulocyte-macrophage colony-stimulating factor
-
10.1099/vir.0.025395-0 21123547
-
Fiorentini S, Luganini A, Dell'Oste V, Lorusso B, Cervi E, Caccuri F, Bonardelli S, Landolfo S, Caruso A, Gribaudo G (2011) Human cytomegalovirus productively infects lymphatic endothelial cells and induces a secretome that promotes angiogenesis and lymphangiogenesis through interleukin-6 and granulocyte-macrophage colony-stimulating factor. J Gen Virol 92(Pt 3):650-660. doi: 10.1099/vir.0.025395-0
-
(2011)
J Gen Virol
, vol.92
, Issue.PART 3
, pp. 650-660
-
-
Fiorentini, S.1
Luganini, A.2
Dell'Oste, V.3
Lorusso, B.4
Cervi, E.5
Caccuri, F.6
Bonardelli, S.7
Landolfo, S.8
Caruso, A.9
Gribaudo, G.10
-
117
-
-
77958601145
-
Role of interleukin-17 in lymphangiogenesis in non-small-cell lung cancer: Enhanced production of vascular endothelial growth factor C in non-small-cell lung carcinoma cells
-
10.1111/j.1349-7006.2010.01684.x 20825419
-
Chen X, Xie Q, Cheng X, Diao X, Cheng Y, Liu J, Xie W, Chen Z, Zhu B (2010) Role of interleukin-17 in lymphangiogenesis in non-small-cell lung cancer: enhanced production of vascular endothelial growth factor C in non-small-cell lung carcinoma cells. Cancer Sci 101(11):2384-2390. doi: 10.1111/j.1349-7006.2010.01684.x
-
(2010)
Cancer Sci
, vol.101
, Issue.11
, pp. 2384-2390
-
-
Chen, X.1
Xie, Q.2
Cheng, X.3
Diao, X.4
Cheng, Y.5
Liu, J.6
Xie, W.7
Chen, Z.8
Zhu, B.9
-
118
-
-
80055064696
-
A novel pro-lymphangiogenic function for Th17/IL-17
-
10.1182/blood-2011-01-332049 3208279 21908425
-
Chauhan SK, Jin Y, Goyal S, Lee HS, Fuchsluger TA, Lee HK, Dana R (2011) A novel pro-lymphangiogenic function for Th17/IL-17. Blood 118(17):4630-4634. doi: 10.1182/blood-2011-01-332049
-
(2011)
Blood
, vol.118
, Issue.17
, pp. 4630-4634
-
-
Chauhan, S.K.1
Jin, Y.2
Goyal, S.3
Lee, H.S.4
Fuchsluger, T.A.5
Lee, H.K.6
Dana, R.7
-
119
-
-
70349847434
-
Macrophages participate in lymphangiogenesis in idiopathic diffuse alveolar damage through CCL19-CCR7 signal
-
10.1016/j.humpath.2009.03.021 19540558
-
Yamashita M, Iwama N, Date F, Shibata N, Miki H, Yamauchi K, Sawai T, Sato S, Takahashi T, Ono M (2009) Macrophages participate in lymphangiogenesis in idiopathic diffuse alveolar damage through CCL19-CCR7 signal. Hum Pathol 40(11):1553-1563. doi: 10.1016/j.humpath.2009.03.021
-
(2009)
Hum Pathol
, vol.40
, Issue.11
, pp. 1553-1563
-
-
Yamashita, M.1
Iwama, N.2
Date, F.3
Shibata, N.4
Miki, H.5
Yamauchi, K.6
Sawai, T.7
Sato, S.8
Takahashi, T.9
Ono, M.10
-
120
-
-
84866917884
-
The CXCL12-CXCR4 chemokine pathway: A novel axis regulates lymphangiogenesis
-
10.1158/1078-0432.CCR-12-0708 22932666
-
Zhuo W, Jia L, Song N, Lu XA, Ding Y, Wang X, Song X, Fu Y, Luo Y (2012) The CXCL12-CXCR4 chemokine pathway: a novel axis regulates lymphangiogenesis. Clin Cancer Res 18(19):5387-5398. doi: 10.1158/1078-0432.CCR-12-0708
-
(2012)
Clin Cancer Res
, vol.18
, Issue.19
, pp. 5387-5398
-
-
Zhuo, W.1
Jia, L.2
Song, N.3
Lu, X.A.4
Ding, Y.5
Wang, X.6
Song, X.7
Fu, Y.8
Luo, Y.9
-
121
-
-
1642475162
-
Cyclooxygenase-2 induces EP1- and HER-2/Neu-dependent vascular endothelial growth factor-C up-regulation: A novel mechanism of lymphangiogenesis in lung adenocarcinoma
-
14744769
-
Su JL, Shih JY, Yen ML, Jeng YM, Chang CC, Hsieh CY, Wei LH, Yang PC, Kuo ML (2004) Cyclooxygenase-2 induces EP1- and HER-2/Neu-dependent vascular endothelial growth factor-C up-regulation: a novel mechanism of lymphangiogenesis in lung adenocarcinoma. Cancer Res 64(2):554-564
-
(2004)
Cancer Res
, vol.64
, Issue.2
, pp. 554-564
-
-
Su, J.L.1
Shih, J.Y.2
Yen, M.L.3
Jeng, Y.M.4
Chang, C.C.5
Hsieh, C.Y.6
Wei, L.H.7
Yang, P.C.8
Kuo, M.L.9
-
122
-
-
79955583515
-
Roles of prostaglandin E2-EP3/EP4 receptor signaling in the enhancement of lymphangiogenesis during fibroblast growth factor-2-induced granulation formation
-
10.1161/ATVBAHA.110.222356 21311040
-
Hosono K, Suzuki T, Tamaki H, Sakagami H, Hayashi I, Narumiya S, Alitalo K, Majima M (2011) Roles of prostaglandin E2-EP3/EP4 receptor signaling in the enhancement of lymphangiogenesis during fibroblast growth factor-2-induced granulation formation. Arterioscler Thromb Vasc Biol 31(5):1049-1058. doi: 10.1161/ATVBAHA.110.222356
-
(2011)
Arterioscler Thromb Vasc Biol
, vol.31
, Issue.5
, pp. 1049-1058
-
-
Hosono, K.1
Suzuki, T.2
Tamaki, H.3
Sakagami, H.4
Hayashi, I.5
Narumiya, S.6
Alitalo, K.7
Majima, M.8
-
123
-
-
38949125782
-
Nitric oxide mediates lymphatic vessel activation via soluble guanylate cyclase alpha1beta1-impact on inflammation
-
10.1096/fj.07-8873com 17855621
-
Kajiya K, Huggenberger R, Drinnenberg I, Ma B, Detmar M (2008) Nitric oxide mediates lymphatic vessel activation via soluble guanylate cyclase alpha1beta1-impact on inflammation. FASEB J 22(2):530-537. doi: 10.1096/fj.07-8873com
-
(2008)
FASEB J
, vol.22
, Issue.2
, pp. 530-537
-
-
Kajiya, K.1
Huggenberger, R.2
Drinnenberg, I.3
Ma, B.4
Detmar, M.5
-
124
-
-
66149142809
-
Endothelial nitric oxide synthase mediates lymphangiogenesis and lymphatic metastasis
-
10.1158/0008-5472.CAN-08-4051 2670480 19318557
-
Lahdenranta J, Hagendoorn J, Padera TP, Hoshida T, Nelson G, Kashiwagi S, Jain RK, Fukumura D (2009) Endothelial nitric oxide synthase mediates lymphangiogenesis and lymphatic metastasis. Cancer Res 69(7):2801-2808. doi: 10.1158/0008-5472.CAN-08-4051
-
(2009)
Cancer Res
, vol.69
, Issue.7
, pp. 2801-2808
-
-
Lahdenranta, J.1
Hagendoorn, J.2
Padera, T.P.3
Hoshida, T.4
Nelson, G.5
Kashiwagi, S.6
Jain, R.K.7
Fukumura, D.8
|