Application of microchip electrophoresis sodium dodecyl sulfate for the evaluation of change of degradation species of therapeutic antibodies in stability testing

Analytical Sciences

Volumn 30, Issue 4, 2014, Pages 483-488

  Yagi, Yuki ^a   Kakehi, Kazuaki ^b   Hayakawa, Takao ^b   Suzuki, Shigeo ^b  

^a KYOWA HAKKO KOGYO CO LTD   (Japan)

^b KINKI UNIVERSITY   (Japan)

Author keywords

antibody; capillary electrophoresis; Microchip electrophoresis

Indexed keywords

ANTIBODIES; CAPILLARY ELECTROPHORESIS; INSTRUMENT TESTING; MICROPROCESSOR CHIPS; SULFUR COMPOUNDS;

CELL CULTIVATION; DEGRADED PRODUCTS; DETECTION METHODS; FINE RESOLUTION; FORMULATION DEVELOPMENT; MICROCHIP ELECTROPHORESIS; STABILITY TESTING; THERAPEUTIC ANTIBODIES;

SODIUM DODECYL SULFATE;

MONOCLONAL ANTIBODY;

CHEMISTRY; DEVICES; DRUG STABILITY; LAB ON A CHIP; MICROCHIP ELECTROPHORESIS; MOLECULAR WEIGHT; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROCEDURES; PROTEIN DEGRADATION; PROTEIN STABILITY; QUALITY CONTROL; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; TEMPERATURE;

ANTIBODIES, MONOCLONAL; DRUG STABILITY; ELECTROPHORESIS, MICROCHIP; ELECTROPHORESIS, POLYACRYLAMIDE GEL; LAB-ON-A-CHIP DEVICES; MOLECULAR WEIGHT; PROTEIN STABILITY; PROTEOLYSIS; QUALITY CONTROL; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TEMPERATURE;

EID: 84898887741     PISSN: 09106340     EISSN: 13482246     Source Type: Journal    
DOI: 10.2116/analsci.30.483     Document Type: Article

References (28)

1. J. G. Elvin, R. G. Couston, and C. F. van der Walle, Int. J. Pharm., 2013, 440, 83.
2. A. Eon-Duval, H. Broly, and R. Gleixner, Biotechnol. Prog., 2012, 28, 608.
3. S. Barandun, P. Kistler, F. Jeunet, and H. Isliker, Vox Sang., 1962, 7, 157.
4. E. F. Ellis and C. S. Henney, J. Allergy, 1969, 43, 45.
5. A. J. Cordoba, B. J. Shyong, D. Breen, and R. J. Harris, J. Chromatogr. B: Anal. Technol. Biomed. Life Sci., 2005, 818, 115.
6. M. Page, C. Ling, P. Dilger, M. Bentley, T. Forsey, C. Longstaff, and R. Thorpe, Vox Sang., 1995, 69, 183.
7. Y. D. Liu, A. M. Goetze, R. B. Bass, and G. C. Flynn, J. Biol. Chem., 2011, 286, 11211.
8. R. J. Harris, Dev. Biol. (Basel, Switz.), 2005, 122, 117.
9. H. S. Gadgil, P. V. Bondarenko, G. D. Pipes, T. M. Dillon, D. Banks, J. Abel, G. R. Kleemann, and M. J. Treuheit, Anal. Biochem., 2006, 355, 165.
10. L. W. Dick, D. Qiu, R. B. Wong, and K. C. Cheng, Biotechnol. Bioeng., 2010, 105, 515.
11. L. W. Dick, D. Qiu, and K. C. Cheng, J. Chromatogr. B: Anal. Technol. Biomed. Life Sci., 2009, 877, 3841.
12. A. Beck, E. Wagner-Rousset, D. Ayoub, A. Van Dorsselaer, and S. Sanglier-Cianférani, Anal. Chem., 2013, 85, 715.
13. S. Fekete, A. L. Gassner, S. Rudaz, J. Schappler, and D. Guillarme, TrAC, Trends Anal. Chem., 2013, 42, 74.
14. S. Hjerten, J. Chromatogr., 1983, 270, 1.
15. A. S. Cohen and B. J. Karger, J. Chromatogr., 1987, 397, 409.
16. J. Liu, S. Abid, and M. S. Lee, Anal. Biochem., 1995, 229, 221.
17. G. Hunt, K. G. Moorhouse, and A. B. Chen, J. Chromatogr. A, 1996, 744, 295.
18. G. Hunt and W. Nashabeh, Anal. Chem., 1999, 71, 2390.
19. O. Salas-Solano, B. Tomlinson, S. Du, M. Parker, A. Strahan, and S. Ma, Anal. Chem., 2006, 78, 6583.
20. D. A. Michels, M. Parker, and O. Salas-Solano, Electrophoresis, 2012, 33, 815.
21. M. E. Le, A. Vizel, and K. M. Hutterer, Electrophoresis, 2013, 34, 1369.
22. M. Eggers and D. Ehrlich, Hematol. Pathol., 1995, 9, 1.
23. S. Yao, D. S. Anex, W. B. Caldwell, D. W. Arnold, K. B. Smith, and P. G. Schultz, Proc. Natl. Acad. Sci. U. S. A., 1999, 96, 5372.
24. L. Bousse, S. Mouradian, A. Minalla, H. Yee, K. Williams, and R. Dubrow, Anal. Chem., 2001, 73, 1207.
25. J. Han and A. K. Singh, J. Chromatogr. A, 2004, 1049, 205.
26. H. Nagata, M. Tabuchi, K. Hirano, and Y. Baba, Electrophoresis, 2005, 26, 2687.
27. X. Chen, K. Tang, M. Lee, and G. C. Flynn, Electrophoresis, 2008, 29, 4993.
28. X. Chen and G. C. Flynn, J. Chromatogr. B: Anal. Technol. Biomed. Life Sci., 2009, 877, 3012.