Induced nitric oxide synthetase and peroxiredoxin expression in intramucosal poorly differentiated gastric cancer of young patients

Pathology International

Volumn 64, Issue 4, 2014, Pages 155-163

  Hirahashi, Minako ^a   Koga, Yutaka ^a   Kumagai, Reiko ^a   Aishima, Shinichi ^c   Taguchi, Kenichi ^b   Oda, Yoshinao ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b NATIONAL KYUSHU CANCER CENTER   (Japan)

^c SAGA UNIVERSITY   (Japan)

Author keywords

8OHdG; Gastric cancer; INOS; Peroxiredoxin; Thioredoxin

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; NITRIC OXIDE SYNTHASE; PEROXIREDOXIN 1; PEROXIREDOXIN 2; PEROXIREDOXIN 3; REACTIVE NITROGEN SPECIES; THIOREDOXIN; 8-OXO-7-HYDRODEOXYGUANOSINE; DEOXYGUANOSINE; INDUCIBLE NITRIC OXIDE SYNTHASE; NOS2 PROTEIN, HUMAN; PEROXIREDOXIN; PRDX2 PROTEIN, HUMAN;

ADULT; AGED; ARTICLE; CANCER CELL; CARCINOGENESIS; CLINICAL ARTICLE; CONTROLLED STUDY; EPITHELIUM; EPITHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MALE; MUCOSA CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; STOMACH CANCER; AGE DISTRIBUTION; ANALOGS AND DERIVATIVES; CELL DIFFERENTIATION; GASTRITIS; METABOLISM; MIDDLE AGED; PATHOLOGY; PHYSIOLOGY; STOMACH; STOMACH MUCOSA; STOMACH TUMOR; YOUNG ADULT;

ADULT; AGE DISTRIBUTION; AGED; CELL DIFFERENTIATION; DEOXYGUANOSINE; FEMALE; GASTRIC MUCOSA; GASTRITIS; HUMANS; MALE; MIDDLE AGED; NITRIC OXIDE SYNTHASE TYPE II; PEROXIREDOXINS; STOMACH; STOMACH NEOPLASMS; YOUNG ADULT;

EID: 84898878592     PISSN: 13205463     EISSN: 14401827     Source Type: Journal    
DOI: 10.1111/pin.12152     Document Type: Article

References (34)

1. Correa P. Human gastric carcinogenesis: A multistep and multifactorial process - First American Cancer Society Award lecture on cancer epidemiology and prevention. Cancer Res 1992; 52: 6735-6740.
2. Kabashima A, Yao T, Sugimachi K etal. Gastric or intestinal phenotypic expression in the carcinomas and background mucosa of multiple early gastric carcinomas. Histopathology 2000; 37: 513-522.
3. Goto A, Hirahashi M, Osada M etal. Aberrant activation-induced cytidine deaminase expression is associated with mucosal intestinalization in the early stage of gastric cancer. Virchows Arch 2011; 458: 717-724.
4. Ming SC. Cellular and molecular pathology of gastric carcinoma and precursor lesions: A critical review. Gastric Cancer 1998; 1: 31-50.
5. Nakamura T, Yao T, Niho Y etal. A clinicopathological study in young patients with gastric carcinoma. J Surg Oncol 1999; 71: 214-219.
6. Mori M, Sugimachi K, Ohiwa T etal. Early gastric carcinoma in Japanese patients under 30 years of age. Br J Surg 1985; 7: 289-291.
7. Hirahashi M, Yao T, Matsumoto T etal. Intramucosal gastric adenocarcinoma of poorly differentiated type in the young is characterized by Helicobacter pylori infection and antral lymphoid hyperplasia. Mod Pathol 2007; 20: 29-34.
8. Kim DY, Ryu SY, Kim YJ etal. Clinicopathological characteristics of gastric carcinoma in young patients. Langenbecks Arch Surg 2003; 388: 245-249.
9. Farinati F, Cardin R, Degan P etal. Oxidative DNA damage accumulation in gastric carcinogenesis. Gut 1998; 42: 351-356.
10. Miyazawa M, Suzuki H, Masaoka T etal. Suppressed apoptosis in the inflamed gastric mucosa of Helicobacter pylori-colonized iNOS-knockout mice. Free Radic Biol Med 2003; 34: 1621-1630.
11. Nam KT, Oh SY, Ahn B, Kim YB etal. Decreased Helicobacter pylori associated gastric carcinogenesis in mice lacking inducible nitric oxide synthase. Gut 2004; 53: 1250-1255.
12. Noh DY, Ahn SJ, Lee RA etal. Overexpression of peroxiredoxin in human breast cancer. Anticancer Res 2001; 21: 2085-2090.
13. Cha MK, Suh KH, Kim IH. Overexpression of peroxiredoxin I and thioredoxin1 in human breast carcinoma. J Exp Clin Cancer Res 2009; 28: 93-104.
14. Burke-Gaffney A, Callister ME, Nakamura H. Thioredoxin: Friend or foe in human disease? Trends Pharmacol Sci 2005; 26: 398-404.
15. Chen MF, Lee KD, Yeh CH etal. Role of peroxiredoxin I in rectal cancer and related to p53 status. Int J Radiat Oncol Biol Phys 2010; 78: 868-878.
16. Dixon MF, Genta RM, Yardley JH etal. Classification and grading of gastritis. The updated Sydney System. International Workshop on the Histopathology of Gastritis, Houston 1994. Am J Surg Pathol 1996; 20: 1161-1181.
17. Suzuki H, Nishizawa T, Tsugawa H etal. Roles of oxidative stress in stomach disorders. J Clin Biochem Nutr 2012; 50: 35-39.
18. Katsurahara M, Kobayashi Y, Iwasa M etal. Reactive nitrogen species mediate DNA damage in Helicobacter pylori-infected gastric mucosa. Helicobacter 2009; 14: 552-558.
19. Fushimi F, Taguchi K, Izumi H etal. Peroxiredoxins, thioredoxin, and Y-box-binding protein-1 are involved in the pathogenesis and progression of dialysis-associated renal cell carcinoma. Virchows Arch 2013; 463: 553-562.
20. Nishibayashi H, Kanayama S, Kiyohara T etal. Helicobacter pylori-induced enlarged-fold gastritis is associated with increased mutagenicity of gastric juice, increased oxidative DNA damage, and an increased risk of gastric carcinoma. J Gastroenterol Hepatol 2003; 18: 1384-1391.
21. Izzotti A, De Flora S, Cartiglia C etal. Interplay between Helicobacter pylori and host gene polymorphisms in inducing oxidative DNA damage in the gastric mucosa. Carcinogenesis 2007; 28: 892-898.
22. Neumann CA, Fang Q. Are peroxiredoxins tumor suppressors? Curr Opin Pharmacol 2007; 7: 375-380.
23. Chang R, Wang E. Mouse translation elongation factor eEF1A-2 interacts with Prdx-I to protect cells against apoptotic death induced by oxidative stress. J Cell Biochem 2007; 100: 267-278.
24. Yuan J, Murrell GA, Trickett A etal. Overexpression of antioxidant enzyme peroxiredoxin 5 protects human tendon cells against apoptosis and loss of cellular function during oxidative stress. Biochim Biophys Acta 2004; 1693: 37-45.
25. Bae JY, Ahn SJ, Han W etal. Peroxiredoxin I and II inhibit H2O2-induced cell death in MCF-7 cell lines. J Cell Biochem 2007; 101: 1038-1045.
26. Fu S, Ramanujam KS, Wong A etal. Increased expression and cellular localization of inducible nitric oxide synthase and cyclooxygnase 2 in Helicobacter pylori gastritis. Gastroenterology 1999; 116: 1319-1329.
27. Tsuji S, Kawano S, Tsuji M etal. Helicobacter pylori extract stimulates inflammatory nitric oxide production. Cancer Lett 1996; 108: 195-200.
28. Kuwahara H, Miyamoto Y, Akaike T etal. Helicobacter pylori urease suppresses bactericidal activity of peroxynitrite via carbon dioxide production. Infect Immun 2000; 68: 4378-4383.
29. Handa O, Naito Y, Yoshikawa T. Redox biology and gastric carcinogenesis: The role of Helicobacter pylori. Redox Rep 2011; 16: 1-7.
30. Bussiere FI, Chaturvedi R, Cheng Y etal. Spermine causes loss of innate immune response to Helicobacter pylori by inhibition of inducible nitric-oxide synthase translation. J Biol Chem 2005; 280: 2409-2412.
31. Gobert AP, McGee DJ, Akhtar M etal. Helicobacter pylori arginase inhibits nitric oxide production by eukayotic cells: A strategy for bacterial survival. Proc Natl Acad Sci U S A 2001; 98: 13844-13849.
32. Greenman C, Stephens P, Smith R etal. Patterns of somatic mutation in human cancer genomes. Nature 2007; 446: 153-158.
33. Shiao YH, Palli D, Buzard GS etal. Implications of p53 mutation spectrum for cancer etiology in gastric cancers of various histologic types from a high-risk area of central Italy. Carcinogenesis 1998; 19: 2145-2149.
34. Ranzani GN, Luinetti O, Padovan LS etal. p53 gene mutations and protein nuclear accumulation are early events in intestinal type gastric cancer but late events in diffuse type. Cancer Epidemiol Biomarkers Prev 1995; 4: 223-231.