Reactive nitrogen species mediate DNA damage in helicobacter pylori-infected gastric mucosa

Helicobacter

Volumn 14, Issue 6, 2009, Pages 552-558

  Katsurahara, Masaki ^a   Kobayashi, Yoshinao ^a   Iwasa, Motoh ^a   Ma, Ning ^b   Inoue, Hiroyuki ^a   Fujita, Naoki ^a   Tanaka, Kyosuke ^a   Horiki, Noriyuki ^a   Gabazza, Esteban C ^a   Takei, Yoshiyuki ^a  

^a MIE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b SUZUKA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

Author keywords

8 nitroguanine; Chronic gastritis; Eradication; Helicobacter pylori; Nitrative stress; Oxidative stress; Reactive nitrogen species

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; 8 NITROGUANINE; AMOXICILLIN; ANTIBODY; CLARITHROMYCIN; DNA; METRONIDAZOLE; OMEPRAZOLE; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE;

ADULT; AGED; ARTICLE; CELL ACTIVITY; CELL INFILTRATION; CLINICAL ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DRUG EFFICACY; EPITHELIUM CELL; ERADICATION THERAPY; FEMALE; GASTRITIS; HELICOBACTER INFECTION; HISTOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFLAMMATORY CELL; INTESTINE METAPLASIA; MALE; NEUTROPHIL; PRACTICE GUIDELINE; PRIORITY JOURNAL; STOMACH ANTRUM; STOMACH EPITHELIUM; STOMACH MUCOSA; TREATMENT OUTCOME;

ADULT; AGED; DNA DAMAGE; FEMALE; GASTRIC MUCOSA; GUANINE; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; MALE; MIDDLE AGED; REACTIVE NITROGEN SPECIES; YOUNG ADULT;

HELICOBACTER PYLORI;

EID: 70449458826     PISSN: 10834389     EISSN: 15235378     Source Type: Journal    
DOI: 10.1111/j.1523-5378.2009.00719.x     Document Type: Article

References (37)

1. Correa P, Fox J, Fontham E, et al. Helicobacter pylori and gastric carcinoma. Serum antibody prevalence in populations with contrasting cancer risks. Cancer 1990 66 : 2569 2574.
2. Davies GR, Simmonds NJ, Stevens TR, Sheaff MT, Banatvala N, Laurenson IF, Blake DR, Rampton DS. Helicobacter pylori stimulates antral mucosal reactive oxygen metabolite production in vivo. Gut 1994 35 : 179 185.
3. Mashimo M, Nishikawa M, Higuchi K, et al. Production of reactive oxygen species in peripheral blood is increased in individuals with Helicobacter pylori infection and decreased after its eradication. Helicobacter 2006 11 : 266 271.
4. Drake IM, Mapstone NP, Schorah CJ, White KL, Chalmers DM, Dixon MF, Axon AT. Reactive oxygen species activity and lipid peroxidation in Helicobacter pylori associated gastritis: relation to gastric mucosal ascorbic acid concentrations and effect of H. pylori eradication. Gut 1998 42 : 768 771.
5. Farinati F, Cardin R, Degan P, Rugge M, Mario FD, Bonvicini P, Naccarato R. Oxidative DNA damage accumulation in gastric carcinogenesis. Gut 1998 42 : 351 356.
6. Fu S, Ramanujam KS, Wong A, Fantry GT, Drachenberg CB, James SP, Meltzer SJ, Wilson KT. Increased expression and cellular localization of inducible nitric oxide synthase and cyclooxygenase 2 in Helicobacter pylori gastritis. Gastroenterology 1999 116 : 1319 1329.
7. Hussain SP, Hofseth LJ, Harris CC. Radical causes of cancer. Nat Rev Cancer 2003 3 : 276 285.
8. Wink DA, Mitchell JB. Chemical biology of nitric oxide: insights into regulatory, cytotoxic, and cytoprotective mechanisms of nitric oxide. Free Rad Biol Med 1998 25 : 434 456.
9. Beckman JS, Koppenol WH. Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly. Am J Physiol 1996 271 : C1424 37.
10. Hofseth LJ, Khan MA, Ambrose M, et al. The adaptive imbalance in base excision-repair enzymes generates microsatellite instability in chronic inflammation. J Clin Invest 2003 112 : 1887 1894.
11. Ohshima H, Takemichi M, Sawa T. Chemical basis of inflammation-induced carcinogenesis. Arch Biochem Biophys 2003 417 : 3 11.
12. Witherell HL, Hiatt RA, Replogle M, Parsonnet J. Helicobacter pylori infection and urinary excretion of 8-hydroxy-2-deoxyguanosine, an oxidative DNA adduct. Cancer Epidemiol Biomarkers Prev 1998 7 : 91 96.
13. Ma N, Adachi Y, Hiraku Y, et al. Accumulation of 8-nitroguanine in human gastric epithelium induced by Helicobacter pylori infection. Biochem Biophys Res Commun 2004 319 : 506 510.
14. Pignatelli B, Bancel B, Plummer M, Toyokuni S, Patricot LM, Ohshima H. Helicobacter pylori eradication attenuates oxidative stress in human gastric mucosa. Am J Gastroenterol 2001 96 : 1758 1766.
15. Pinlaor S, Ma N, Hiraku Y, et al. Repeated infection with Opisthorchis viverrini induces accumulation of 8-nitroguanine and 8-oxo-7, 8-dihydro-2′-deoxyguanine in the bile duct of hamsters via inducible nitric oxide synthase. Carcinogenesis 2004 25 : 1535 1542.
16. Dixon MF, Genta RM, Yardley JH, Correa P. Classification and grading of gastritis. The updated Sydney System. International Workshop on the Histopathology of Gastritis. Am J Surg Pathol 1996 20 : 1161 1181.
17. Parkin DM, Bray F, Ferlay J, Pisani P. Global cancer statistics, 2002. CA Cancer J Clin 2005 55 : 74 108.
18. Farinati F, Cardin R, Russo VM, Busatto G, Franco M, Rugge M. Helicobacter pylori CagA status, mucosal oxidative damage and gastritis phenotype: a potential pathway to cancer? Helicobacter 2003 8 : 227 234.
19. Selbach M, Moese S, Hauck CR, Meyer TF, Backert S. Src is the kinase of the Helicobacter pylori CagA protein in vitro and in vivo. J Biol Chem 2002 277 : 6775 6778.
20. Tammer I, Brandt S, Hartig R, König W, Backert S. Activation of Abl by Helicobacter pylori: a novel kinase for CagA and crucial mediator of host cell scattering. Gastroenterology 2007 132 : 1309 1319.
21. Higashi H, Tsutsumi R, Muto S, Sugiyama T, Azuma T, Asaka M, Hatakeyama M. SHP-2 tyrosine phosphatase as an intracellular target of Helicobacter pylori CagA protein. Science 2002 295 : 683 686. (Pubitemid 34111828)
22. Ushijima T, Nakajima T, Maekita T. DNA methylation as a marker for the past and future. J Gastroenterol 2006 41 : 401 407.
23. Maekita T, Nakazawa K, Mihara M, et al. High levels of aberrant DNA methylation in Helicobacter pylori-infected gastric mucosae and its possible association with gastric cancer risk. Clin Cancer Res 2006 12 : 989 995.
24. Matsumoto Y, Marusawa H, Kinoshita K, et al. Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium. Nat Med 2007 13 : 470 476.
25. Hatakeyama M. Hericobacter pylori and gastric carcinogenesis. J Gastroenterol 2009 44 : 239 248.
26. Suzuki H, Miura S, Imaeda H, et al. Enhanced levels of chemiluminescence and platelet activating factor in urease-positive gastric ulcers. Free Radic Biol Med 1996 20 : 449 454.
27. Bagchi D, McGinn TR, Ye X, Bagchi M, Krohn RL, Chatterjee A, Stohs SJ. Helicobacter pylori-induced oxidative stress and DNA damage in a primary culture of human gastric mucosal cells. Digest Dis Sci 2002 47 : 1405 1412.
28. Ganster RW, Taylor BS, Shao L, Geller DA. Complex regulation of human inducible nitric oxide synthase gene transcription by Stat 1 and NF-kappa B. Proc Natl Acad Sci USA 2001 98 : 8638 8643.
29. Kawanishi S, Hiraku Y, Pinlaor S, Ma N. Oxidative and nitrative DNA damage in animals and patients with inflammatory diseases in relation to inflammation-related carcinogenesis. Biol Chem 2006 387 : 365 372.
30. Fukumura D, Jain RK. Role of nitric oxide in angiogenesis and microcirculation in tumors. Cancer Metastasis Rev 1998 17 : 77 89.
31. Kolb H, Kolb BV. Nitric oxide: a pathogenetic factor in autoimmunity. Immunol Today 1992 13 : 157 160.
32. Kim SF, Huri DA, Snyder SH. Inducible nitric oxide synthase binds, S-nitrosylates, and activates cyclooxygenase-2. Science 2005 310 : 1966 1970.
33. Lejeune P, Lagadec P, Onier N, Pinard D, Ohshima H, Jeannin JF. Nitric oxide involvement in tumor-induced immunosuppression. J Immunol 1994 152 : 5077 5083.
34. Naito Y, Takagi T, Okada H, et al. Expression of inducible nitric oxide synthase and nitric oxide-modified proteins in Helicobacter pylori-associated atrophic gastric mucosa. J Gastroenterol Hepatol 2008 23 : S250 7.
35. Danese S, Cremonini F, Armuzzi A, et al. Helicobacter pylori CagA-positive strains affect oxygen free radicals generation by gastric mucosa. Scand J Gastroenterol 2001 36 : 247 250.
36. Farinati F, Cardin R, Russo VM, Busatto G, Franco M, Falda A, Mescoli C, Rugge M. Differential effects of Helicobacter pylori eradication on oxidative DNA damage at the gastroesophageal junction and at the gastric antrum. Cancer Epidemiol Biomarkers Prev 2004 13 : 1722 1728.
37. Li WQ, Zhang L, Ma JL, Zhang Y, Li JY, Pan KF, You WC. Association between genetic polymorphisms of DNA base excision repair genes and evolution of precancerous gastric lesions in a Chinese population. Carcinogenesis 2009 30 : 500 505.