Characterization and engineering of the ethylmalonyl-CoA pathway towards the improved heterologous production of polyketides in Streptomyces venezuelae

Applied Microbiology and Biotechnology

Volumn 98, Issue 8, 2014, Pages 3701-3713

  Jung, Won Seok ^a   Kim, Eunji ^a   Yoo, Young Ji ^a   Ban, Yeon Hee ^a   Kim, Eun Ji ^a   Yoon, Yeo Joon ^a  

^a Ewha Womans University   (South Korea)

Author keywords

Ethylmalonyl CoA; Heterologous host; Polyketide; Streptomyces venezuelae; Tylactone

Indexed keywords

BIOCHEMISTRY; BIOSYNTHESIS; GENE ENCODING; GENE EXPRESSION; KETONES;

ETHYLMALONYL-COA; HETEROLOGOUS HOST; POLYKETIDES; STREPTOMYCES VENEZUELAE; TYLACTONE;

BACTERIA;

COBAMAMIDE; MALONYL COENZYME A; POLYKETIDE; TYLOSIN; ACYL COENZYME A; ANTIINFECTIVE AGENT; ETHYLMALONYL-COENZYME A;

ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; BIOSYNTHESIS; CONTROLLED STUDY; FERMENTATION; GENE CLUSTER; GENE DELETION; GENETIC MANIPULATION; METABOLIC ENGINEERING; METABOLITE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTOPLAST; REGULATOR GENE; REGULATORY MECHANISM; STREPTOMYCES VENEZUELAE; SUPPLEMENTATION; DNA SEQUENCE; GENE EXPRESSION; GENETICS; METABOLISM; MOLECULAR GENETICS; STREPTOMYCES;

ACYL COENZYME A; ANTI-BACTERIAL AGENTS; GENE DELETION; GENE EXPRESSION; METABOLIC ENGINEERING; METABOLIC NETWORKS AND PATHWAYS; MOLECULAR SEQUENCE DATA; POLYKETIDES; SEQUENCE ANALYSIS, DNA; STREPTOMYCES;

EID: 84898871398     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-013-5503-8     Document Type: Article

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