In silico accounting of novel pyridazine analogues as h-PTP 1B inhibitors: Pharmacophore modelling, atom-based 3D QSAR and docking studies

Medicinal Chemistry Research

Volumn 23, Issue 6, 2014, Pages 2701-2711

  Mahapatra, Manoj Kumar ^a   Kumar, Rajnish ^a   Malla, Priyanka ^a   Kumar, Manoj ^a  

^a PANJAB UNIVERSITY   (India)

Author keywords

3D QSAR; Glide; PHASE; PTP 1B; Pyridazine

Indexed keywords

HYDROGEN; PROTEIN TYROSINE PHOSPHATASE 1B INHIBITOR; PYRIDAZINE DERIVATIVE;

ARTICLE; COMPUTER MODEL; DRUG RECEPTOR BINDING; HYDROGEN BOND; HYDROPHOBICITY; HYPOTHESIS; MOLECULAR DOCKING; PHARMACOPHORE; QUANTITATIVE STRUCTURE ACTIVITY RELATION; VALIDATION PROCESS;

EID: 84898871173     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-013-0797-8     Document Type: Article

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