Methylenetetrahydrofolate reductase polymorphisms and breast cancer risk in Chinese population: A meta-analysis of 22 case-control studies

Tumor Biology

Volumn 35, Issue 2, 2014, Pages 1695-1701

  Liang, Hongjie ^a   Yan, Yulan ^a   Li, Taijie ^a   Li, Ruolin ^a   Li, Meng ^a   Li, Shan ^a   Qin, Xue ^a  

^a GUANGXI MEDICAL UNIVERSITY   (China)

Author keywords

Breast cancer; Meta analysis; Methylenetetrahydrofolate reductase; Polymorphism

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2);

ALLELE; ARTICLE; BREAST CANCER; CANCER RISK; CHINESE; DNA POLYMORPHISM; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; META ANALYSIS; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SENSITIVITY ANALYSIS;

BREAST NEOPLASMS; CASE-CONTROL STUDIES; CHINA; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); POLYMORPHISM, GENETIC; RISK FACTORS;

EID: 84898849558     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-013-1234-9     Document Type: Article

References (44)

1. Smigal C, Jemal A,Ward E, Cokkinides V, Smith R, Howe HL, et al. Trends in breast cancer by race and ethnicity: update 2006. CA Cancer J Clin. 2006;56:168-83. (Pubitemid 43847927)
2. Parkin DM, Bray F, Ferlay J, Pisani P. Global cancer statistics, 2002. CA Cancer J Clin. 2005;55:74-108. (Pubitemid 40372904)
3. Sturgeon SR, Schairer C, Grauman D, El Ghormli L, Devesa S. Trends in breast cancer mortality rates by region of the United States, 1950-1999. Cancer Causes Control. 2004;15:987-95. (Pubitemid 41449279)
4. Fang Q, Qiong W, Zhang L, Xiaoli M. Analysis of breast cancer epidemic. Chin J Soc Med. 2012;29:333-5.
5. Hankinson SE, Colditz GA, Willett WC. Towards an integrated model for breast cancer etiology: the lifelong interplay of genes, lifestyle, and hormones. Breast Cancer Res. 2004;6:213-8.
6. Dumitrescu RG, Cotarla I. Understanding breast cancer risk-where do we stand in 2005? J Cell Mol Med. 2005;9:208-21.
7. Qiu LX, Yuan H, Yu KD,Mao C, Chen B, Zhan P, et al. Glutathione S-transferase M1 polymorphism and breast cancer susceptibility: a meta-analysis involving 46,281 subjects. Breast Cancer Res Treat. 2010;121:703-8.
8. Qiu LX, Yao L,Mao C, Chen B, Zhan P, Xue K, et al. TGFB1 L10P polymorphism is associated with breast cancer susceptibility: evidence from a meta-analysis involving 47,817 subjects. Breast Cancer Res Treat. 2010;123:563-7.
9. Qiu LX, Yao L, Xue K, Zhang J, Mao C, Chen B, et al. BRCA2 N372H polymorphism and breast cancer susceptibility: a meta-analysis involving 44,903 subjects. Breast Cancer Res Treat. 2010;123:487-90.
10. Rosenblatt DS. Methylenetetrahydrofolate reductase. Clin Invest Med. 2001;24:56-9. (Pubitemid 32226238)
11. Lucock M. Folic acid: nutritional biochemistry, molecular biology, and role in disease processes. Mol Genet Metab. 2000;71:121-38.
12. Lucock M. Is folic acid the ultimate functional food component for disease prevention? BMJ. 2004;328:211-4. (Pubitemid 38147076)
13. Diakite B, Tazzite A, Hamzi K, Jouhadi H, Nadifi S. Methylenetetrahydrofolate reductase C677T polymorphism and breast cancer risk in moroccan women. Afr Health Sci. 2012;12:204-9.
14. de Cassia Carvalho Barbosa R, da Costa DM, Cordeiro DE, Vieira AP, Rabenhorst SH. Interaction of MTHFR C677Tand A1298C, and MTR A2756G gene polymorphisms in breast cancer risk in a population in northeast Brazil. Anticancer Res. 2012;32:4805-11.
15. Taioli E, Garza MA, Ahn YO, Bishop DT, Bost J, Budai B, et al. Meta- and pooled analyses of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and colorectal cancer: a HuGE-GSEC review. Am J Epidemiol. 2009;170:1207-21.
16. Boccia S, Hung R, Ricciardi G, Gianfagna F, Ebert MP, Fang JY, et al. Meta- and pooled analyses of the methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and gastric cancer risk: a huge-GSEC review. Am J Epidemiol. 2008;167:505-16. (Pubitemid 351323315)
17. De Mattia E, Toffoli G. C677T and A1298C MTHFR polymorphisms, a challenge for antifolate and fluoropyrimidine-based therapy personalisation. Eur J Cancer. 2009;45:1333-51.
18. Wu XY, Ni J, Xu WJ, Zhou T, Wang X. Interactions between MTHFR C677T-A1298C variants and folic acid deficiency affect breast cancer risk in a Chinese population. Asian Pac J Cancer Prev. 2012;13:2199-206.
19. Gao CM, Tang JH, Cao HX, Ding JH,Wu JZ,Wang J, et al.MTHFR polymorphisms, dietary folate intake and breast cancer risk in Chinese women. J Hum Genet. 2009;54:414-8.
20. Chou YC,Wu MH, Yu JC, Lee MS, Yang T, Shih HL, et al. Genetic polymorphisms of the methylenetetrahydrofolate reductase gene, plasma folate levels and breast cancer susceptibility: a case-control study in Taiwan. Carcinogenesis. 2006;27:2295-300. (Pubitemid 44644819)
21. Shrubsole MJ, Gao YT, Cai Q, Shu XO, Dai Q, Hebert JR, et al. MTHFR polymorphisms, dietary folate intake, and breast cancer risk: results from the Shanghai Breast Cancer Study. Cancer Epidemiol Biomarkers Prev. 2004;13:190-6. (Pubitemid 38222548)
22. Inoue M, Robien K, Wang R, Van Den Berg DJ, Koh WP, Yu MC. Green tea intake, MTHFR/TYMS genotype and breast cancer risk: the Singapore Chinese Health Study. Carcinogenesis. 2008;29:1967-72.
23. Yu CP, Wu MH, Chou YC, Yang T, You SL, Chen CJ, et al. Breast cancer risk associated with multigenotypic polymorphisms in folate-metabolizing genes: a nested case - control study in Taiwan. Anticancer Res. 2007;27:1727-32. (Pubitemid 46807266)
24. Lin WY, Chou YC, Wu MH, Huang HB, Jeng YL, Wu CC, et al. The MTHFR C677T polymorphism, estrogen exposure and breast cancer risk: a nested case-control study in Taiwan. Anticancer Res. 2004;24:3863-8.
25. Wu Y, Yuan X, Zheng H, Chu Yanhui, Zhang Jiaying. Northeast methylenetetrahydrofolate reductase gene c677t single nucleotide polymorphisms and susceptibility to breast cancer research. Modern Oncology 2010;18:2375-2378.
26. Yuan H, Xu X, Wang Z. Mthfrc677t Gene polymorphism and breast cancer. Mudanjiang Med Coll. 2009;30:2-4.
27. Hua Z, Wang Y, Ni J, Ge F, Zou T. Serum folate, vitamin b12 concentration and mthfr, ms gene polymorphism associated with risk of breast cancer research. Mod Oncol. 2011;19:428-31.
28. Kan X, Zou T, Wu X, Wang X. Yunnan methylenetetrahydrofolate reductase gene polymorphism associated with breast cancer susceptibility. Cancer Res. 2007;34:716-8.
29. Li W, Shengqiang C. . Mthfr c 677 t gene polymorphism associated with breast cancer. Practical. J Med. 2009;25:2031-3.
30. Lin J, Chen S, Li W. Mthfr C677T and a1298c gene polymorphisms associated with breast cancer. Prelim Stud Mod Hosp. 2010;10:15-7.
31. Qi J, Miao X, Tan W, Yu C-y, Liang G, Lvwen F, et al. Methylenetetrahydrofolate reductase gene single nucleotide polymorphisms and breast cancer risk. Chin J Oncol. 2004;26:287-9.
32. Higgins JP, Thompson SG. Quantifying heterogeneity in a metaanalysis. Stat Med. 2002;21:1539-58.
33. DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials. 1986;7:177-88. (Pubitemid 17189972)
34. Mantel N, Haenszel W. Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst. 1959;22:719-48.
35. Zamora-Ros R, Rothwell JA, Scalbert A, Knaze V, Romieu I, Slimani N, et al. Dietary intakes and food sources of phenolic acids in the European Prospective Investigation into Cancer and Nutrition (epic) study. Br J Nutr. 2013;14:1-12.
36. Tobias A, Campbell MJ. Modelling influenza epidemics in the relation between black smoke and total mortality. A sensitivity analysis. J Epidemiol Community Health. 1999;53:583-4. (Pubitemid 29401837)
37. Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ. 1997;315:629-34. (Pubitemid 27387172)
38. Begg CB, Mazumdar M. Operating characteristics of a rank correlation test for publication bias. Biometrics. 1994;50:1088-101.
39. Ma X, Qi X, Chen C, Lin H, Xiong H, Li Y, et al. Association between CYP19 polymorphisms and breast cancer risk: results from 10,592 cases and 11,720 controls. Breast Cancer Res Treat. 2010;122:495-501.
40. Sergentanis TN, Economopoulos KP. Association of two CASP8 polymorphisms with breast cancer risk: a meta-analysis. Breast Cancer Res Treat. 2010;120:229-34.
41. Yuan W, Xu L, Feng Y, Yang Y, Chen W, Wang J, et al. The hoGG1 Ser326Cys polymorphism and breast cancer risk: a meta-analysis. Breast Cancer Res Treat. 2010;122:835-42.
42. Macis D, Maisonneuve P, Johansson H, Bonanni B, Botteri E, Iodice S, et al. Methylenetetrahydrofolate reductase (MTHFR) and breast cancer risk: a nested-case-control study and a pooled meta-analysis. Breast Cancer Res Treat. 2007;106:263-71. (Pubitemid 350045014)
43. Fujisawa T, Ikegami H, Kawaguchi Y, Ogihara T. Meta-analysis of the association of Trp64Arg polymorphism of beta 3-adrenergic receptor gene with body mass index. J Clin Endocrinol Metab. 1998;83:2441-4. (Pubitemid 28503044)
44. Liwei L, Chunyu L, Ruifa H. Association between manganese superoxide dismutase gene polymorphism and risk of prostate cancer: a meta-analysis. Urology. 2009;74:884-8.