Impact of the controlled release of a connexin 43 peptide on corneal wound closure in an STZ model of type I diabetes

PLoS ONE

Volumn 9, Issue 1, 2014, Pages

  Moore, Keith ^a   Ghatnekar, Gautam ^b,c   Gourdie, Robert G ^d   Potts, Jay D ^a  

^a UNIVERSITY OF SOUTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b FirstString Research Inc   (United States)

^c MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^d VIRGINIA TECH CARILION SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGENTS ACTING ON THE EYE; ALGINIC ACID; ALPHA CARBOXY TERMINUS 1 PEPTIDE; CONNEXIN 43; CXCL11 CHEMOKINE; CYTOKERATIN 8; ESTROGEN RECEPTOR ALPHA; GLUCOSE TRANSPORTER 4; PEPTIDE DERIVATIVE; POLOXAMER; POLYORNITHINE; TRANSFORMING GROWTH FACTOR BETA2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; CORNEA INJURY; DISEASE MODEL; DRUG DELIVERY SYSTEM; DRUG EFFECT; EPITHELIAL MESENCHYMAL TRANSITION; FLUORESCENCE ANALYSIS; GEL; IN VITRO STUDY; INFLAMMATION; INSULIN DEPENDENT DIABETES MELLITUS; KERATITIS; MALE; MICROCAPSULE; NONHUMAN; PROTEIN MODIFICATION; RAT; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; TREATMENT RESPONSE; WOUND CLOSURE; WOUND HEALING;

ANIMALS; BIOLOGICAL MARKERS; BLOTTING, WESTERN; CAPSULES; CONNEXIN 43; CORNEAL DISEASES; DELAYED-ACTION PREPARATIONS; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITHELIAL-MESENCHYMAL TRANSITION; GLUCOSE TRANSPORTER TYPE 4; INFLAMMATION; MALE; PEPTIDE FRAGMENTS; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; WOUND HEALING;

EID: 84898845677     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0086570     Document Type: Article

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