Estradiol increases angiotensin II type 1 receptor in hearts of ovariectomized rats

Journal of Endocrinology

Volumn 200, Issue 1, 2009, Pages 75-84

  Ricchiuti, Vincent ^a   Lian, Christine G ^a   Oestreicher, Eveline M ^a   Tran, Loc ^a   Stone, James R ^b   Yao, Tham ^a   Seely, Ellen W ^a   Williams, Gordon H ^a   Adler, Gail K ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDOSTERONE; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II; CAVEOLIN 3; CELL PROTEIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ESTRADIOL; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR 1; ESTROGEN RECEPTOR 2; MITOGEN ACTIVATED PROTEIN KINASE 3; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; OSTEOPONTIN; PLACEBO; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN ED1; PROTEIN KINASE C DELTA; UNCLASSIFIED DRUG;

ALDOSTERONE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; FEMALE; HEART; HEART DISEASE; HEART WEIGHT; INFLAMMATION; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SYSTOLIC BLOOD PRESSURE; TISSUE HOMOGENATE; UTERUS WEIGHT; WISTAR RAT;

ANGIOTENSIN II; ANIMALS; ESTRADIOL; ESTROGEN REPLACEMENT THERAPY; FEMALE; GENE EXPRESSION; HEART; HUMANS; MODELS, ANIMAL; MYOCARDIUM; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE TYPE III; OVARIECTOMY; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN KINASE C-DELTA; RATS; RATS, WISTAR; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTORS, ESTROGEN; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 67449158131     PISSN: 00220795     EISSN: 14796805     Source Type: Journal    
DOI: 10.1677/JOE-08-0199     Document Type: Article

References (44)

1. Alexaki VI, Charalampopoulos I, Kampa M, Nifli AP, Hatzoglou A, Gravanis A & Castanas E 2006 Activation of membrane estrogen receptors induce pro-survival kinases. Journal of Steroid Biochemistry and Molecular Biology 98 97-110.
2. Barchiesi F, Jackson EK, Imthurn B, Fingerle J, Gillespie DG & Dubey RK 2004 Differential regulation of estrogen receptor subtypes alpha and beta in human aortic smooth muscle cells by oligonucleotides and estradiol. Journal of Clinical Endocrinology and Metabolism 89 2373-2381.
3. Brunner F, Maier R, Andrew P, Wolkart G, Zechner R & Mayer B 2003 Attenuation of myocardial ischemia/reperfusion injury in mice with myocyte-specific overexpression of endothelial nitric oxide synthase. Cardiovascular Research 57 55-62.
4. Bueno OF, De Windt LJ, Tymitz KM, Witt SA, Kimball TR, Klevitsky R, Hewett TE, Jones SP, Lefer DJ, Peng CF et al. 2000 The MEK1-ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice. EMBO Journal 19 6341-6350.
5. Collins P, Rosano GM, Sarrel PM, Ulrich L, Adamopoulos S, Beale CM, McNeill JG & Poole-Wilson PA 1995 17β-Estradiol attenuates acetyl-choline-induced coronary arterial constriction in women but not men with coronary heart disease. Circulation 92 24-30.
6. 2C entry mechanisms of arterial vasoconstriction by sex hormones. Clinical and Experimental Pharmacology and Physiology 26 707-715.
7. Damy T, Ratajczak P, Shah AM, Camors E, Marty I, Hasenfuss G, Marotte F, Samuel JL & Heymes C 2004 Increased neuronal nitric oxide synthase-derived NO production in the failing human heart. Lancet 363 1365-1367.
8. Feron O & Kelly RA 2001 The caveolar paradox: suppressing, inducing, and terminating eNOS signaling. Circulation Research 88 129-131.
9. Gallagher PE, Li P, Lenhart JR, Chappell MC & Brosnihan KB 1999 Estrogen regulation of angiotensin-converting enzyme mRNA. Hypertension 33 323-328.
10. Gorodeski GI, Yang T, Levy MN, Goldfarb J & Utian WH 1995 Effects of estrogen in vivo on coronary vascular resistance in perfused rabbit hearts. American Journal of Physiology 269 R1333-R1338.
11. Hayashi T, Fukuto JM, Ignarro LJ & Chaudhuri G 1992 Basal release of nitric oxide from aortic rings is greater in female rabbits than in male rabbits: implications for atherosclerosis. PNAS 89 11259-11263.
12. Herrington DM, Reboussin DM, Brosnihan KB, Sharp PC, Shumaker SA, Snyder TE, Hugel S, Reincke M, Stromer H, Winning J et al. 1999 Evidence against a role of physiological concentrations of estrogen in post-myocardial infarction remodeling. Journal of the American College of Cardiology 34 1427-1434.
13. Herrington DM, Reboussin DM, Brosnihan KB, Sharp PC, Shumaker SA, Snyder TE, Furberg CD, Kowalchuk GJ, Stuckey TD, Rogers WJ et al. 2000 Effects of estrogen replacement on the progression of coronary-artery atherosclerosis. New England Journal of Medicine 343 522-529.
14. Hisamoto K & Bender JR 2005 Vascular cell signaling by membrane estrogen receptors. Steroids 70 382-387.
15. Huang A, Sun D, Koller A & Kaley G 2000 17β-Estradiol restores endothelial nitric oxide release to shear stress in arterioles of male hypertensive rats. Circulation 101 94-100.
16. Hügel S, Reincke M, Strömmer H, Winning J, Horn M, Dienesch C, Mora P, Schmidt HH, Allolio B & Neubauer S 1999 Evidence against a role of physiological concentrations of estrogen in post-myocardial infarction remodelling. Journal of the American College of Cardiologists 34 1427-1434.
17. Hulley S, Grady D, Bush T, Furberg C, Herrington D, Riggs B & Vittinghoff E 1998 Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research Group. Journal of the American Medical Association 280 605-613.
18. Keyes LE, Moore LG, Walchak SJ & Dempsey EC 1996 Pregnancy-stimulated growth of vascular smooth muscle cells: importance of protein kinase C-dependent synergy between estrogen and platelet-derived growth factor. Journal of Cellular Physiology 166 22-32.
19. Khalil RA 2005 Sex harmones as potential modulators of vascular action in hypertension. Hypertension 46 249-254.
20. Klett C, Ganten D, Hellmann W, Kaling M, Ryffel GU, Weimar-Ehl T & Hackenthal E 1992 Regulation of hepatic angiotensinogen synthesis and secretion by steroid hormones. Endocrinology 130 3660-3668.
21. Koh KK 2002 Effects of estrogen on the vascular wall: vasomotor function and inflammation. Cardiovascular Research 55 714-726.
22. Krishnamurthi K, Verbalis JG, Zheng W, Wu Z, Clerch LB & Sandberg K 1999 Estrogen regulates angiotensin AT1 receptor expression via cytosolic proteins that bind to the 5′ leader sequence of the receptor mRNA. Endocrinology 140 5435-5438.
23. Manson JE, Hsia J, Johnson KC, Rossouw JE, Assaf AR, Lasser NL, Trevisan M, Black HR, Heckbert SR, Detrano R et al. 2003 Estrogen plus progestin and the risk of coronary heart disease. New England Journal of Medicine 349 523-534.
24. Martinez DV, Rocha R, Matsumura M, Oestreicher E, Ochoa-Maya M, Roubsanthisuk W, Williams GH & Adler GK 2002 Cardiac damage prevention by eplerenone: comparison with low sodium diet or potassium loading. Hypertension 39 614-618.
25. Mendelsohn ME & Karas RH 1999 The protective effects of estrogen on the cardiovascular system. New England Journal of Medicine 340 1801-1811.
26. Oestreicher EM, Martinez-Vasquez D, Stone JR, Jonasson L, Roubsanthisuk W, Mukasa K & Adler GK 2003 Aldosterone and not plasminogen activator inhibitor-1 is a critical mediator of early angiotensin II/ NG-nitro-L-arginine methyl ester-induced myocardial injury. Circulation 108 2517-2523.
27. Oestreicher EM, Guo C, Seely EW, Kikuchi T, Martinez-Vasquez D, Jonasson L, Yao T, Burr D, Mayoral S, Roubsanthisuk W et al. 2006 Estradiol increases proteinuria and angiotensin II type 1 receptor in kidneys of rats receiving L-NAME and angiotensin II. Kidney International 70 1759-1768.
28. Patten RD, Pourati I, Aronovitz MJ, Baur J, Celestin F, Chen X, Michael A, Haq S, Nuedling S, Grohe C et al. 2004 17β-Estradiol reduces cardiomyocyte apoptosis in vivo and in vitro via activation of phospho-inositide-3 kinase/Akt signaling. Circulation Research 95 692-699.
29. Pedram A, Razandi M, Aitkenhead M & Levin ER 2005 Estrogen inhibits cardiomyocyte hypertrophy in vitro. Antagonism of calcineurin-related hypertrophy through induction of MCIP1. Journal of Biological Chemistry 280 26339-26348.
30. Pinto S, Virdis A, Ghiadoni L, Bernini G, Lombardo M, Petraglia F, Genazzani AR, Taddei S & Salvetti A 1997 Endogenous estrogen and acetylcholine-induced vasodilation in normotensive women. Hypertension 29 268-273.
31. Reis SE, Gloth ST, Blumenthal RS, Resar JR, Zacur HA, Gerstenblith G & Brinker JA 1994 Ethinyl estradiol acutely attenuates abnormal coronary vasomotor responses to acetylcholine in postmenopausal women. Circulation 89 52-60.
32. Rocha R, Stier CT Jr, Kifor I, Ochoa-Maya MR, Rennke HG, Williams GH & Adler GK 2000 Aldosterone: a mediator of myocardial necrosis and renal arteriopathy. Endocrinology 141 3871-3878.
33. Rocha R, Martin-Berger CL, Yang P, Scherrer R, Delyani J & McMahon E 2002 Selective aldosterone blockade prevents angiotensin II/salt-induced vascular inflammation in the rat heart. Endocrinology 143 4828-4836.
34. Rossouw JE, Anderson GL, Prentice RL, LaCroix AZ, Kooperberg C, Stefanick ML, Jackson RD, Beresford SA, Howard BV, Johnson KC et al. 2002 Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women's Health Initiative randomized controlled trial. Journal of the American Medical Association 288 321-333.
35. Schunkert H, Danser AH, Hense HW, Derkx FH, Kurzinger S & Riegger GA 1997 Effects of estrogen replacement therapy on the renin-angiotensin system in postmenopausal women. Circulation 95 39-45.
36. Seely EW, Brosnihan KB, Jeunemaitre X, Okamura K, Williams GH, Hollenberg NK & Herrington DM 2004 Effects of conjugated oestrogen and droloxifene on the renin-angiotensin system, blood pressure and renal blood flow in postmenopausal women. Clinical Endocrinology 60 315-321.
37. Smith LH, Coats SR, Qin H, Petrie MS, Covington JW, Su M, Eren M & Vaughan DE 2004 Differential and opposing regulation of PAI-1 promoter activity by estrogen receptor alpha and estrogen receptor beta in endothelial cells. Circulation Research 95 269-275.
38. Stampfer MJ, Colditz GA, Willett WC, Manson JE, Rosner B, Speizer FE & Hennekens CH 1991 Postmenopausal estrogen therapy and cardiovascular disease. Ten-year follow-up from the nurses' health study. New England Journal of Medicine 325 756-762.
39. Stier CT Jr, Chander PN, Rosenfeld L & Powers CA 2003 Estrogen promotes microvascular pathology in female stroke-prone spontaneously hypertensive rats. American Journal of Physiology. Endocrinology and Metabolism 285 E232-E239.
40. Turchin A, Guo CZ, Adler GK, Ricchiuti V, Kohane IS & Williams GH 2006 Effect of acute aldosterone administration on gene expression profile in the heart. Endocrinology 147 3183-3189.
41. Williams TM & Lisanti MP 2004 The Caveolin genes: from cell biology to medicine. Annals of Medicine 36 584-595.
42. Wu Z, Zheng W & Sandberg K 2003 Estrogen regulates adrenal angiotensin type 1 receptors by modulating adrenal angiotensin levels. Endocrinology 144 1350-1356.
43. Xu Y, Arenas IA, Armstrong SJ & Davidge ST 2003 Estrogen modulation of left ventricular remodeling in the aged heart. Cardiovascular Research 57 388-394.
44. Yamaleyeva LM, Pendergrass KD, Pirro NT, Gallagher PE, Groban L & Chappell MC 2007 Ovariectomy is protective against renal injury in the high-salt-fed older mRen2.Lewis rat. American Journal of Physiology. Heart and Circulatory Physiology 293 H2064-H2071.