Valeriana amurensis improves Amyloid-beta 1-42 induced cognitive deficit by enhancing cerebral cholinergic function and protecting the brain neurons from apoptosis in mice

Journal of Ethnopharmacology

Volumn 153, Issue 2, 2014, Pages 318-325

  Wang, Qiuhong ^a,b   Wang, Changfu ^a   Shu, Zunpeng ^a   Chan, Kelvin ^c,d   Huang, Shuming ^a,b,c,d   Li, Yan ^a   Xiao, Yang ^a   Wu, Lihua ^a   Kuang, Haixue ^a   Sun, Xiaobo ^b  

^a HEILONGJIANG UNIVERSITY OF CHINESE MEDICINE   (China)

^b INSTITUTE OF MEDICINAL PLANT DEVELOPMENT   (China)

^c UNIVERSITY OF WESTERN SYDNEY   (Australia)

^d UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Alzheimer's disease; Amyloid beta; Cholinergic function; Cognitive deficit; Valeriana amurensis

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA-PROTEIN (1-42); NEUROPROTECTIVE AGENT; PEPTIDE FRAGMENT; PLANT EXTRACT; VALERIAN;

ANIMAL; APOPTOSIS; BRAIN; BRAIN CORTEX; CHEMICALLY INDUCED; CHOLINERGIC NERVE CELL; COGNITION DISORDERS; DOSE RESPONSE; DRUG EFFECTS; INSTITUTE FOR CANCER RESEARCH MOUSE; ISOLATION AND PURIFICATION; MALE; METABOLISM; MOUSE; PHYSIOLOGY; PLANT ROOT; RANDOMIZATION; RHIZOME; TOXICITY;

AMYLOID BETA-PEPTIDES; ANIMALS; APOPTOSIS; BRAIN; CEREBRAL CORTEX; CHOLINERGIC NEURONS; COGNITION DISORDERS; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; MICE; MICE, INBRED ICR; NEUROPROTECTIVE AGENTS; PEPTIDE FRAGMENTS; PLANT EXTRACTS; PLANT ROOTS; RANDOM ALLOCATION; RHIZOME; VALERIAN;

EID: 84898813677     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2013.11.017     Document Type: Article

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