메뉴 건너뛰기




Volumn 31, Issue 4, 2014, Pages 263-282

A benefit-risk assessment of the use of proton pump inhibitors in the elderly

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ANTIBIOTIC AGENT; ANTICOAGULANT AGENT; CLOPIDOGREL; CORTICOSTEROID; CYANOCOBALAMIN; CYTOCHROME P450 2C19; HISTAMINE H2 RECEPTOR ANTAGONIST; LANSOPRAZOLE; LEVOTHYROXINE; NONSTEROID ANTIINFLAMMATORY AGENT; OMEPRAZOLE; PANTOPRAZOLE; PROTON PUMP INHIBITOR; RABEPRAZOLE;

EID: 84898778423     PISSN: 1170229X     EISSN: 11791969     Source Type: Journal    
DOI: 10.1007/s40266-014-0166-4     Document Type: Review
Times cited : (40)

References (171)
  • 1
    • 13744261420 scopus 로고    scopus 로고
    • Updated guidelines for the diagnosis and treatment of gastroesophageal reflux disease
    • 15654800
    • DeVault KR, Castell DO. Updated guidelines for the diagnosis and treatment of gastroesophageal reflux disease. Am J Gastroenterol. 2005;100(1):190-200.
    • (2005) Am J Gastroenterol , vol.100 , Issue.1 , pp. 190-200
    • Devault, K.R.1    Castell, D.O.2
  • 2
    • 84885413867 scopus 로고    scopus 로고
    • IMS Health Report New Jersey: IMS Accessed 21th Aug 2013
    • IMS Health Report. declining medicine use and costs: for better or worse? New Jersey: IMS; 2013. http://www.imshealth.com/cds/ims/Global/Content/ Insights/IMS%20Institute%20for%20Healthcare%20Informatics/2012%20U.S. %20Medicines%20Report/2012-U.S.Medicines-Report.pdf. Accessed 21th Aug 2013.
    • (2013) Declining Medicine Use and Costs: For Better or Worse
  • 3
    • 84898825134 scopus 로고    scopus 로고
    • National college of health insurances Accessed 5th Aug 2013
    • National college of health insurances. http://www.gipdatabank.nl/ databank.asp. Accessed 5th Aug 2013.
  • 5
    • 84869437442 scopus 로고    scopus 로고
    • Drug policy for an aging population - The European Medicines Agency's geriatric medicines strategy
    • 23171092
    • Cerreta F, Eichler HG, Rasi G. Drug policy for an aging population - the European Medicines Agency's geriatric medicines strategy. N Engl J Med. 2012;367(21):1972-4.
    • (2012) N Engl J Med , vol.367 , Issue.21 , pp. 1972-1974
    • Cerreta, F.1    Eichler, H.G.2    Rasi, G.3
  • 6
    • 0036307464 scopus 로고    scopus 로고
    • Causal association in pharmacovigilance and pharmacoepidemiology: Thoughts on the application of the Austin Bradford-Hill criteria
    • 12071785
    • Shakir SA, Layton D. Causal association in pharmacovigilance and pharmacoepidemiology: thoughts on the application of the Austin Bradford-Hill criteria. Drug Saf. 2002;25(6):467-71.
    • (2002) Drug Saf , vol.25 , Issue.6 , pp. 467-471
    • Shakir, S.A.1    Layton, D.2
  • 9
    • 61949239030 scopus 로고    scopus 로고
    • Guidelines for prevention of NSAID-related ulcer complications
    • 19240698
    • Lanza FL, Chan FK, Quigley EM. Guidelines for prevention of NSAID-related ulcer complications. Am J Gastroenterol. 2009;104(3):728-38.
    • (2009) Am J Gastroenterol , vol.104 , Issue.3 , pp. 728-738
    • Lanza, F.L.1    Chan, F.K.2    Quigley, E.M.3
  • 10
    • 84866365307 scopus 로고    scopus 로고
    • Prescription of nonselective NSAIDs, coxibs and gastroprotective agents in the era of rofecoxib withdrawal - A 617,400-patient study
    • 22928490
    • Valkhoff VE, van Soest EM, Masclee GM, de Bie S, Mazzaglia G, Molokhia M, et al. Prescription of nonselective NSAIDs, coxibs and gastroprotective agents in the era of rofecoxib withdrawal - a 617,400-patient study. Aliment Pharmacol Ther. 2012;36(8):790-9.
    • (2012) Aliment Pharmacol Ther , vol.36 , Issue.8 , pp. 790-799
    • Valkhoff, V.E.1    Van Soest, E.M.2    Masclee, G.M.3    De Bie, S.4    Mazzaglia, G.5    Molokhia, M.6
  • 11
    • 0001834897 scopus 로고    scopus 로고
    • Risk of upper gastrointestinal bleeding and perforation associated with low-dose aspirin as plain and enteric-coated formulations
    • 32172 11228592
    • de Abajo FJ, Garcia Rodriguez LA. Risk of upper gastrointestinal bleeding and perforation associated with low-dose aspirin as plain and enteric-coated formulations. BMC Clin Pharmacol. 2001;1(1):1-8.
    • (2001) BMC Clin Pharmacol , vol.1 , Issue.1 , pp. 1-8
    • De Abajo, F.J.1    Garcia Rodriguez, L.A.2
  • 12
    • 84898826581 scopus 로고    scopus 로고
    • Risk of upper gastrointestinal bleeding in a cohort of new users of low-dose ASA for secondary prevention of cardiovascular outcomes
    • Cea Soriano L, Rodriguez LA. Risk of upper gastrointestinal bleeding in a cohort of new users of low-dose ASA for secondary prevention of cardiovascular outcomes. Front Pharmacol. 2012;1(126):1-9.
    • (2012) Front Pharmacol , vol.1 , Issue.126 , pp. 1-9
    • Cea Soriano, L.1    Rodriguez, L.A.2
  • 13
    • 33845457204 scopus 로고    scopus 로고
    • Risk of upper gastrointestinal ulcer bleeding associated with selective cyclo-oxygenase-2 inhibitors, traditional non-aspirin non-steroidal anti-inflammatory drugs, aspirin and combinations
    • 1856452 16687434
    • Lanas A, Garcia-Rodriguez LA, Arroyo MT, Gomollon F, Feu F, Gonzalez-Perez A, et al. Risk of upper gastrointestinal ulcer bleeding associated with selective cyclo-oxygenase-2 inhibitors, traditional non-aspirin non-steroidal anti-inflammatory drugs, aspirin and combinations. Gut. 2006;55(12):1731-8.
    • (2006) Gut , vol.55 , Issue.12 , pp. 1731-1738
    • Lanas, A.1    Garcia-Rodriguez, L.A.2    Arroyo, M.T.3    Gomollon, F.4    Feu, F.5    Gonzalez-Perez, A.6
  • 14
    • 33846803757 scopus 로고    scopus 로고
    • Low-dose aspirin and upper gastrointestinal damage: Epidemiology, prevention and treatment
    • 17257477
    • Lanas A, Scheiman J. Low-dose aspirin and upper gastrointestinal damage: epidemiology, prevention and treatment. Curr Med Res Opin. 2007;23(1):163-73.
    • (2007) Curr Med Res Opin , vol.23 , Issue.1 , pp. 163-173
    • Lanas, A.1    Scheiman, J.2
  • 15
    • 84883739771 scopus 로고    scopus 로고
    • Low-dose acetylsalicylic acid and gastrointestinal ulcers or bleeding-A cohort study of the effects of proton pump inhibitor use patterns
    • 23800296
    • Hedberg J, Sundstrom J, Thuresson M, Aarskog P, Oldgren J, Bodegard J. Low-dose acetylsalicylic acid and gastrointestinal ulcers or bleeding-a cohort study of the effects of proton pump inhibitor use patterns. J Intern Med. 2013;274(4):371-80.
    • (2013) J Intern Med , vol.274 , Issue.4 , pp. 371-380
    • Hedberg, J.1    Sundstrom, J.2    Thuresson, M.3    Aarskog, P.4    Oldgren, J.5    Bodegard, J.6
  • 16
    • 56749183852 scopus 로고    scopus 로고
    • ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use: A report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents
    • 18836135
    • Bhatt DL, Scheiman J, Abraham NS, Antman EM, Chan FK, Furberg CD, et al. ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use: a report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents. Circulation. 2008;118(18):1894-909.
    • (2008) Circulation , vol.118 , Issue.18 , pp. 1894-1909
    • Bhatt, D.L.1    Scheiman, J.2    Abraham, N.S.3    Antman, E.M.4    Chan, F.K.5    Furberg, C.D.6
  • 17
    • 84883311080 scopus 로고    scopus 로고
    • Suboptimal prescribing of proton-pump inhibitors in low-dose aspirin users: A cohort study in primary care
    • de Jong HJ, Korevaar JC, van Dijk L, Voogd E, van Dijk CE, van Oijen MG. Suboptimal prescribing of proton-pump inhibitors in low-dose aspirin users: a cohort study in primary care. BMJ Open. 2013;3(7) 3003044
    • (2013) BMJ Open. , vol.3 , Issue.7 , pp. 3003044
    • De Jong, H.J.1    Korevaar, J.C.2    Van Dijk, L.3    Voogd, E.4    Van Dijk, C.E.5    Van Oijen, M.G.6
  • 18
    • 80655144428 scopus 로고    scopus 로고
    • Suboptimal gastroprotective coverage of NSAID use and the risk of upper gastrointestinal bleeding and ulcers: An observational study using three European databases
    • 21636644
    • van Soest EM, Valkhoff VE, Mazzaglia G, Schade R, Molokhia M, Goldstein JL, et al. Suboptimal gastroprotective coverage of NSAID use and the risk of upper gastrointestinal bleeding and ulcers: an observational study using three European databases. Gut. 2011;60(12):1650-9.
    • (2011) Gut , vol.60 , Issue.12 , pp. 1650-1659
    • Van Soest, E.M.1    Valkhoff, V.E.2    Mazzaglia, G.3    Schade, R.4    Molokhia, M.5    Goldstein, J.L.6
  • 19
    • 74849114254 scopus 로고    scopus 로고
    • International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding
    • 20083829
    • Barkun AN, Bardou M, Kuipers EJ, Sung J, Hunt RH, Martel M, et al. International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding. Ann Intern Med. 2010;152(2):101-13.
    • (2010) Ann Intern Med , vol.152 , Issue.2 , pp. 101-113
    • Barkun, A.N.1    Bardou, M.2    Kuipers, E.J.3    Sung, J.4    Hunt, R.H.5    Martel, M.6
  • 20
    • 84879195648 scopus 로고    scopus 로고
    • Cyclo-oxygenase-2 inhibitors or nonselective NSAIDs plus gastroprotective agents: What to prescribe in daily clinical practice?
    • 3687334 23710837
    • Masclee GM, Valkhoff VE, van Soest EM, Schade R, Mazzaglia G, Molokhia M, et al. Cyclo-oxygenase-2 inhibitors or nonselective NSAIDs plus gastroprotective agents: what to prescribe in daily clinical practice? Aliment Pharmacol Ther. 2013;38(2):178-89.
    • (2013) Aliment Pharmacol Ther , vol.38 , Issue.2 , pp. 178-189
    • Masclee, G.M.1    Valkhoff, V.E.2    Van Soest, E.M.3    Schade, R.4    Mazzaglia, G.5    Molokhia, M.6
  • 21
    • 0035076344 scopus 로고    scopus 로고
    • The risk of upper gastrointestinal complications associated with nonsteroidal anti-inflammatory drugs, glucocorticoids, acetaminophen, and combinations of these agents
    • García Rodríguez LA, Hernández-Díaz S. The risk of upper gastrointestinal complications associated with nonsteroidal anti-inflammatory drugs, glucocorticoids, acetaminophen, and combinations of these agents. Arthritis Res. 2001;3(2):96-101.
    • (2001) Arthritis Res , vol.3 , Issue.2 , pp. 96-101
    • García Rodríguez, L.A.1    Hernández-Díaz, S.2
  • 22
    • 0035370434 scopus 로고    scopus 로고
    • Steroids and risk of upper gastrointestinal complications
    • 11390328
    • Hernandez-Diaz S, Rodriguez LA. Steroids and risk of upper gastrointestinal complications. Am J Epidemiol. 2001;153(11):1089-93.
    • (2001) Am J Epidemiol , vol.153 , Issue.11 , pp. 1089-1093
    • Hernandez-Diaz, S.1    Rodriguez, L.A.2
  • 23
    • 33749681586 scopus 로고    scopus 로고
    • Use of single and combined antithrombotic therapy and risk of serious upper gastrointestinal bleeding: Population based case-control study
    • 1592384 16984924
    • Hallas J, Dall M, Andries A, Andersen BS, Aalykke C, Hansen JM, et al. Use of single and combined antithrombotic therapy and risk of serious upper gastrointestinal bleeding: population based case-control study. BMJ. 2006;333(7571):726.
    • (2006) BMJ , vol.333 , Issue.7571 , pp. 726
    • Hallas, J.1    Dall, M.2    Andries, A.3    Andersen, B.S.4    Aalykke, C.5    Hansen, J.M.6
  • 25
    • 0026517111 scopus 로고
    • Effect of aging on gastric and duodenal mucosal prostaglandin concentrations in humans
    • 1551520
    • Cryer B, Redfern JS, Goldschmiedt M, Lee E, Feldman M. Effect of aging on gastric and duodenal mucosal prostaglandin concentrations in humans. Gastroenterology. 1992;102:1118-23.
    • (1992) Gastroenterology , vol.102 , pp. 1118-1123
    • Cryer, B.1    Redfern, J.S.2    Goldschmiedt, M.3    Lee, E.4    Feldman, M.5
  • 26
    • 0026692035 scopus 로고
    • Factors influencing gastroduodenal mucosal prostaglandin concentrations: Roles of smoking and aging
    • 1546863
    • Cryer G, Lee E, Feldman M. Factors influencing gastroduodenal mucosal prostaglandin concentrations: roles of smoking and aging. Ann Intern Med. 1992;116(8):636-40.
    • (1992) Ann Intern Med , vol.116 , Issue.8 , pp. 636-640
    • Cryer, G.1    Lee, E.2    Feldman, M.3
  • 27
    • 0033625184 scopus 로고    scopus 로고
    • Symptom severity and oesophageal chemosensitivity to acid in older and young patients with gastro-oesophageal reflux
    • 10791446
    • Fass R, Pulliam G, Johnson C, Garewal HS, Sampliner RE. Symptom severity and oesophageal chemosensitivity to acid in older and young patients with gastro-oesophageal reflux. Age Ageing. 2000;29(2):125-30.
    • (2000) Age Ageing , vol.29 , Issue.2 , pp. 125-130
    • Fass, R.1    Pulliam, G.2    Johnson, C.3    Garewal, H.S.4    Sampliner, R.E.5
  • 28
    • 0031014806 scopus 로고    scopus 로고
    • Evidence for diminished visceral pain with aging: Studies using graded intraesophageal balloon distension
    • 9038868
    • Lasch H, Castell DO, Castell JA. Evidence for diminished visceral pain with aging: studies using graded intraesophageal balloon distension. Am J Physiol. 1997;272(1 Pt 1):G1-3.
    • (1997) Am J Physiol , vol.272 , Issue.1 PART 1
    • Lasch, H.1    Castell, D.O.2    Castell, J.A.3
  • 29
    • 15844369552 scopus 로고    scopus 로고
    • Atrophic gastritis and Helicobacter pylori infection in patients with reflux esophagitis treated with omeprazole or fundoplication
    • 8598839
    • Kuipers EJ, Lundell L, Klinkenberg-Knol EC, Havu N, Festen HP, Liedman B, et al. Atrophic gastritis and Helicobacter pylori infection in patients with reflux esophagitis treated with omeprazole or fundoplication. N Engl J Med. 1996;334(16):1018-22.
    • (1996) N Engl J Med , vol.334 , Issue.16 , pp. 1018-1022
    • Kuipers, E.J.1    Lundell, L.2    Klinkenberg-Knol, E.C.3    Havu, N.4    Festen, H.P.5    Liedman, B.6
  • 30
    • 0031454877 scopus 로고    scopus 로고
    • Helicobacter pylori gastritis and epithelial cell proliferation in patients with reflux oesophagitis after treatment with lansoprazole
    • 1891604 9462205
    • Berstad AE, Hatlebakk JG, Maartmann-Moe H, Berstad A, Brandtzaeg P. Helicobacter pylori gastritis and epithelial cell proliferation in patients with reflux oesophagitis after treatment with lansoprazole. Gut. 1997;41(6):740-7.
    • (1997) Gut , vol.41 , Issue.6 , pp. 740-747
    • Berstad, A.E.1    Hatlebakk, J.G.2    Maartmann-Moe, H.3    Berstad, A.4    Brandtzaeg, P.5
  • 31
    • 84859589351 scopus 로고    scopus 로고
    • Management of Helicobacter pylori infection - The Maastricht IV/Florence consensus report
    • 22491499
    • Malfertheiner P, Megraud F, O'Morain CA, Atherton J, Axon AT, Bazzoli F, et al. Management of Helicobacter pylori infection - the Maastricht IV/Florence consensus report. Gut. 2012;61(5):646-64.
    • (2012) Gut , vol.61 , Issue.5 , pp. 646-664
    • Malfertheiner, P.1    Megraud, F.2    O'Morain, C.A.3    Atherton, J.4    Axon, A.T.5    Bazzoli, F.6
  • 34
    • 84876018043 scopus 로고    scopus 로고
    • Proton pump inhibitors and risk of 1-year mortality and rehospitalization in older patients discharged from acute care hospitals
    • 23460307
    • Maggio M, Corsonello A, Ceda GP, Cattabiani C, Lauretani F, Butto V, et al. Proton pump inhibitors and risk of 1-year mortality and rehospitalization in older patients discharged from acute care hospitals. JAMA Intern Med. 2013;173(7):518-23.
    • (2013) JAMA Intern Med , vol.173 , Issue.7 , pp. 518-523
    • Maggio, M.1    Corsonello, A.2    Ceda, G.P.3    Cattabiani, C.4    Lauretani, F.5    Butto, V.6
  • 35
    • 77955500316 scopus 로고    scopus 로고
    • Use of proton-pump inhibitors and their associated risks among frail elderly nursing home residents
    • 3442330 20586539
    • Teramura-Gronblad M, Hosia-Randell H, Muurinen S, Pitkala K. Use of proton-pump inhibitors and their associated risks among frail elderly nursing home residents. Scand J Prim Health Care. 2010;28(3):154-9.
    • (2010) Scand J Prim Health Care , vol.28 , Issue.3 , pp. 154-159
    • Teramura-Gronblad, M.1    Hosia-Randell, H.2    Muurinen, S.3    Pitkala, K.4
  • 36
    • 79955162230 scopus 로고    scopus 로고
    • The persistent exclusion of older patients from ongoing clinical trials regarding heart failure
    • 21444844
    • Cherubini A, Oristrell J, Pla X, Ruggiero C, Ferretti R, Diestre G, et al. The persistent exclusion of older patients from ongoing clinical trials regarding heart failure. Arch Intern Med. 2011;171(6):550-6.
    • (2011) Arch Intern Med , vol.171 , Issue.6 , pp. 550-556
    • Cherubini, A.1    Oristrell, J.2    Pla, X.3    Ruggiero, C.4    Ferretti, R.5    Diestre, G.6
  • 37
    • 0029912547 scopus 로고    scopus 로고
    • Why we need observational studies to evaluate the effectiveness of health care
    • 2350940 8634569
    • Black N. Why we need observational studies to evaluate the effectiveness of health care. BMJ. 1996;312(7040):1215-8.
    • (1996) BMJ , vol.312 , Issue.7040 , pp. 1215-1218
    • Black, N.1
  • 39
    • 79952699499 scopus 로고    scopus 로고
    • Prevalence and appropriateness of drug prescriptions for peptic ulcer and gastro-esophageal reflux disease in a cohort of hospitalized elderly
    • 21402255
    • Pasina L, Nobili A, Tettamanti M, Salerno F, Corrao S, Marengoni A, et al. Prevalence and appropriateness of drug prescriptions for peptic ulcer and gastro-esophageal reflux disease in a cohort of hospitalized elderly. Eur J Intern Med. 2011;22(2):205-10.
    • (2011) Eur J Intern Med , vol.22 , Issue.2 , pp. 205-210
    • Pasina, L.1    Nobili, A.2    Tettamanti, M.3    Salerno, F.4    Corrao, S.5    Marengoni, A.6
  • 40
    • 38149126506 scopus 로고    scopus 로고
    • Overprescribing proton pump inhibitors
    • 2174763 18174564
    • Forgacs I, Loganayagam A. Overprescribing proton pump inhibitors. BMJ. 2008;336(7634):2-3.
    • (2008) BMJ , vol.336 , Issue.7634 , pp. 2-3
    • Forgacs, I.1    Loganayagam, A.2
  • 42
    • 84856258211 scopus 로고    scopus 로고
    • Potentially inappropriate prescribing in older people with dementia in care homes: A retrospective analysis
    • 22204669
    • Parsons C, Johnston S, Mathie E, Baron N, Machen I, Amador S, et al. Potentially inappropriate prescribing in older people with dementia in care homes: a retrospective analysis. Drugs Aging. 2012;29(2):143-55.
    • (2012) Drugs Aging , vol.29 , Issue.2 , pp. 143-155
    • Parsons, C.1    Johnston, S.2    Mathie, E.3    Baron, N.4    Machen, I.5    Amador, S.6
  • 43
    • 35848952541 scopus 로고    scopus 로고
    • Use of proton pump inhibitors and other acid suppressive medications in newly admitted nursing facility patients
    • 17998118
    • Glew CM, Rentler RJ. Use of proton pump inhibitors and other acid suppressive medications in newly admitted nursing facility patients. J Am Med Dir Assoc. 2007;8(9):607-9.
    • (2007) J Am Med Dir Assoc , vol.8 , Issue.9 , pp. 607-609
    • Glew, C.M.1    Rentler, R.J.2
  • 44
    • 84864143807 scopus 로고    scopus 로고
    • Inappropriate prescribing of proton pump inhibitors in older patients: Effects of an educational strategy
    • 22775478
    • Hamzat H, Sun H, Ford JC, Macleod J, Soiza RL, Mangoni AA. Inappropriate prescribing of proton pump inhibitors in older patients: effects of an educational strategy. Drugs Aging. 2012;29(8):681-90.
    • (2012) Drugs Aging , vol.29 , Issue.8 , pp. 681-690
    • Hamzat, H.1    Sun, H.2    Ford, J.C.3    Macleod, J.4    Soiza, R.L.5    Mangoni, A.A.6
  • 45
    • 0345528221 scopus 로고    scopus 로고
    • Appropriateness of gastric antisecretory therapy in hospital practice
    • 14700112
    • Sebastian SS, Kernan N, Qasim A, O'Morain CA, Buckley M. Appropriateness of gastric antisecretory therapy in hospital practice. Ir J Med Sci. 2003;172(3):115-7.
    • (2003) Ir J Med Sci , vol.172 , Issue.3 , pp. 115-117
    • Sebastian, S.S.1    Kernan, N.2    Qasim, A.3    O'Morain, C.A.4    Buckley, M.5
  • 46
    • 84857518000 scopus 로고    scopus 로고
    • Blinded randomised controlled study of the effect of a discharge communication template on proton pump inhibitor prescribing
    • 22382254
    • Lampen-Smith A, Young J, O'Rourke MA, Balram A, Inns S. Blinded randomised controlled study of the effect of a discharge communication template on proton pump inhibitor prescribing. N Z Med J. 2012;125(1350):30-6.
    • (2012) N Z Med J , vol.125 , Issue.1350 , pp. 30-36
    • Lampen-Smith, A.1    Young, J.2    O'Rourke, M.A.3    Balram, A.4    Inns, S.5
  • 47
    • 78649318940 scopus 로고    scopus 로고
    • Appropriateness of treatment recommendations for PPI in hospital discharge letters
    • 2982961 20694459
    • Ahrens D, Chenot JF, Behrens G, Grimmsmann T, Kochen MM. Appropriateness of treatment recommendations for PPI in hospital discharge letters. Eur J Clin Pharmacol. 2010;66(12):1265-71.
    • (2010) Eur J Clin Pharmacol , vol.66 , Issue.12 , pp. 1265-1271
    • Ahrens, D.1    Chenot, J.F.2    Behrens, G.3    Grimmsmann, T.4    Kochen, M.M.5
  • 48
    • 0036234581 scopus 로고    scopus 로고
    • Continued utilization and costs of proton pump inhibitors after Helicobacter pylori eradication in chronic users of gastrointestinal drugs
    • Klok RM, Brouwers JR, Van den Berg PB, De Jong-Van den Berg LT, Tolley K, Postma MJ. Continued utilization and costs of proton pump inhibitors after Helicobacter pylori eradication in chronic users of gastrointestinal drugs. Aliment Pharmacol Ther. 2002;16(5):1033-4.
    • (2002) Aliment Pharmacol Ther. , vol.16 , Issue.5 , pp. 1033-1034
    • Klok, R.M.1    Brouwers, J.R.2    Van Den Berg, P.B.3    De Jong-Van Den Berg, L.T.4    Tolley, K.5    Postma, M.J.6
  • 49
    • 0034773426 scopus 로고    scopus 로고
    • Lack of symptom benefit following presumptive Helicobacter pylori eradication therapy in primary care
    • 11683691
    • Williams D, O'Kelly P, Kelly A, Feely J. Lack of symptom benefit following presumptive Helicobacter pylori eradication therapy in primary care. Aliment Pharmacol Ther. 2001;15(11):1769-75.
    • (2001) Aliment Pharmacol Ther , vol.15 , Issue.11 , pp. 1769-1775
    • Williams, D.1    O'Kelly, P.2    Kelly, A.3    Feely, J.4
  • 50
    • 0032589694 scopus 로고    scopus 로고
    • Long-term prescribing of proton pump inhibitors in general practice
    • 1313442 10562744
    • Hungin AP, Rubin GP, O'Flanagan H. Long-term prescribing of proton pump inhibitors in general practice. Br J Gen Pract. 1999;49(443):451-3.
    • (1999) Br J Gen Pract , vol.49 , Issue.443 , pp. 451-453
    • Hungin, A.P.1    Rubin, G.P.2    O'Flanagan, H.3
  • 52
    • 84862013434 scopus 로고    scopus 로고
    • Glad you brought it up: A patient-centred programme to reduce proton-pump inhibitor prescribing in general medical practice
    • 22824567
    • Murie J, Allen J, Simmonds R, de Wet C. Glad you brought it up: a patient-centred programme to reduce proton-pump inhibitor prescribing in general medical practice. Qual Prim Care. 2012;20(2):141-8.
    • (2012) Qual Prim Care , vol.20 , Issue.2 , pp. 141-148
    • Murie, J.1    Allen, J.2    Simmonds, R.3    De Wet, C.4
  • 53
    • 0034672827 scopus 로고    scopus 로고
    • Strategies for reducing the prescribing of proton pump inhibitors (PPIs): Patient self-regulation of treatment may be an under-exploited resource
    • 11128270
    • Pollock K, Grime J. Strategies for reducing the prescribing of proton pump inhibitors (PPIs): patient self-regulation of treatment may be an under-exploited resource. Soc Sci Med. 2000;51(12):1827-39.
    • (2000) Soc Sci Med , vol.51 , Issue.12 , pp. 1827-1839
    • Pollock, K.1    Grime, J.2
  • 54
    • 0000140377 scopus 로고    scopus 로고
    • Effect of genetic differences in omeprazole metabolism on cure rates for Helicobacter pylori infection and peptic ulcer
    • 9867757
    • Furuta T, Ohashi K, Kamata T, Takashima M, Kosuge K, Kawasaki T, et al. Effect of genetic differences in omeprazole metabolism on cure rates for Helicobacter pylori infection and peptic ulcer. Ann Intern Med. 1998;129(12):1027-30.
    • (1998) Ann Intern Med , vol.129 , Issue.12 , pp. 1027-1030
    • Furuta, T.1    Ohashi, K.2    Kamata, T.3    Takashima, M.4    Kosuge, K.5    Kawasaki, T.6
  • 55
  • 57
    • 0347359186 scopus 로고    scopus 로고
    • Clinical pharmacology of proton pump inhibitors: What the practising physician needs to know
    • 14664653
    • Robinson M, Horn J. Clinical pharmacology of proton pump inhibitors: what the practising physician needs to know. Drugs. 2003;63(24):2739-54.
    • (2003) Drugs , vol.63 , Issue.24 , pp. 2739-2754
    • Robinson, M.1    Horn, J.2
  • 59
    • 71449111039 scopus 로고    scopus 로고
    • A comparison of the acid-inhibitory effects of esomeprazole and pantoprazole in relation to pharmacokinetics and CYP2C19 polymorphism
    • 19785625
    • Hunfeld NG, Touw DJ, Mathot RA, Mulder PG, VANS RH, Kuipers EJ, et al. A comparison of the acid-inhibitory effects of esomeprazole and pantoprazole in relation to pharmacokinetics and CYP2C19 polymorphism. Aliment Pharmacol Ther. 2010;31(1):150-9.
    • (2010) Aliment Pharmacol Ther , vol.31 , Issue.1 , pp. 150-159
    • Hunfeld, N.G.1    Touw, D.J.2    Mathot, R.A.3    Mulder, P.G.4    Vans, R.H.5    Kuipers, E.J.6
  • 60
    • 84858294210 scopus 로고    scopus 로고
    • A comparison of the acid-inhibitory effects of esomeprazole and rabeprazole in relation to pharmacokinetics and CYP2C19 polymorphism
    • 22324425
    • Hunfeld NG, Touw DJ, Mathot RA, van Schaik RH, Kuipers EJ. A comparison of the acid-inhibitory effects of esomeprazole and rabeprazole in relation to pharmacokinetics and CYP2C19 polymorphism. Aliment Pharmacol Ther. 2012;35(7):810-8.
    • (2012) Aliment Pharmacol Ther , vol.35 , Issue.7 , pp. 810-818
    • Hunfeld, N.G.1    Touw, D.J.2    Mathot, R.A.3    Van Schaik, R.H.4    Kuipers, E.J.5
  • 61
    • 0036795262 scopus 로고    scopus 로고
    • Effect of cytochrome P4502C19 genotypic differences on cure rates for gastroesophageal reflux disease by lansoprazole
    • 12386647
    • Furuta T, Shirai N, Watanabe F, Honda S, Takeuchi K, Iida T, et al. Effect of cytochrome P4502C19 genotypic differences on cure rates for gastroesophageal reflux disease by lansoprazole. Clin Pharmacol Ther. 2002;72(4):453-60.
    • (2002) Clin Pharmacol Ther , vol.72 , Issue.4 , pp. 453-460
    • Furuta, T.1    Shirai, N.2    Watanabe, F.3    Honda, S.4    Takeuchi, K.5    Iida, T.6
  • 62
    • 42149120656 scopus 로고    scopus 로고
    • Effect of CYP2C192 and 17 mutations on pharmacodynamics and kinetics of proton pump inhibitors in Caucasians
    • 2432487 18241283
    • Hunfeld NG, Mathot RA, Touw DJ, van Schaik RH, Mulder PG, Franck PF, et al. Effect of CYP2C192 and 17 mutations on pharmacodynamics and kinetics of proton pump inhibitors in Caucasians. Br J Clin Pharmacol. 2008;65(5):752-60.
    • (2008) Br J Clin Pharmacol , vol.65 , Issue.5 , pp. 752-760
    • Hunfeld, N.G.1    Mathot, R.A.2    Touw, D.J.3    Van Schaik, R.H.4    Mulder, P.G.5    Franck, P.F.6
  • 63
    • 0034904673 scopus 로고    scopus 로고
    • Drug interaction studies with esomeprazole, the (S)-isomer of omeprazole
    • 11510629
    • Andersson T, Hassan-Alin M, Hasselgren G, Rohss K. Drug interaction studies with esomeprazole, the (S)-isomer of omeprazole. Clin Pharmacokinet. 2001;40(7):523-37.
    • (2001) Clin Pharmacokinet , vol.40 , Issue.7 , pp. 523-537
    • Andersson, T.1    Hassan-Alin, M.2    Hasselgren, G.3    Rohss, K.4
  • 65
    • 34547180378 scopus 로고    scopus 로고
    • Drug interactions between proton pump inhibitors and antiretroviral drugs
    • 17428151
    • McCabe SM, Smith PF, Ma Q, Morse GD. Drug interactions between proton pump inhibitors and antiretroviral drugs. Expert Opin Drug Metab Toxicol. 2007;3(2):197-207.
    • (2007) Expert Opin Drug Metab Toxicol , vol.3 , Issue.2 , pp. 197-207
    • McCabe, S.M.1    Smith, P.F.2    Ma, Q.3    Morse, G.D.4
  • 66
    • 84898829665 scopus 로고    scopus 로고
    • Food and Drug Administration. Public Health Advisory: updated safety information about a drug interaction between clopidogrel bisulfate (marketed as Plavix) and omeprazole (marketed as Prilosec and Prilosec OTC) Accessed 7 Aug 2013
    • Food and Drug Administration. Public Health Advisory: updated safety information about a drug interaction between clopidogrel bisulfate (marketed as Plavix) and omeprazole (marketed as Prilosec and Prilosec OTC). http://www.fda.gov/Drugs/DrugSafety/ PostmarketDrugSafetyInformationforPatientsandProviders/ DrugSafetyInformationforHeathcareProfessionals/PublicHealthAdvisories/ucm190825. htm. Accessed 7 Aug 2013.
  • 68
    • 77949690349 scopus 로고    scopus 로고
    • Meta-analysis: The effects of proton pump inhibitors on cardiovascular events and mortality in patients receiving clopidogrel
    • 20102352
    • Kwok CS, Loke YK. Meta-analysis: the effects of proton pump inhibitors on cardiovascular events and mortality in patients receiving clopidogrel. Aliment Pharmacol Ther. 2010;31(8):810-23.
    • (2010) Aliment Pharmacol Ther , vol.31 , Issue.8 , pp. 810-823
    • Kwok, C.S.1    Loke, Y.K.2
  • 69
    • 76349098199 scopus 로고    scopus 로고
    • Cytochrome 2C1917 allelic variant, platelet aggregation, bleeding events, and stent thrombosis in clopidogrel-treated patients with coronary stent placement
    • 20083681
    • Sibbing D, Koch W, Gebhard D, Schuster T, Braun S, Stegherr J, et al. Cytochrome 2C1917 allelic variant, platelet aggregation, bleeding events, and stent thrombosis in clopidogrel-treated patients with coronary stent placement. Circulation. 2010;121(4):512-8.
    • (2010) Circulation , vol.121 , Issue.4 , pp. 512-518
    • Sibbing, D.1    Koch, W.2    Gebhard, D.3    Schuster, T.4    Braun, S.5    Stegherr, J.6
  • 70
    • 84875231630 scopus 로고    scopus 로고
    • No consistent evidence of differential cardiovascular risk amongst proton-pump inhibitors when used with clopidogrel: Meta-analysis
    • 22464478
    • Kwok CS, Jeevanantham V, Dawn B, Loke YK. No consistent evidence of differential cardiovascular risk amongst proton-pump inhibitors when used with clopidogrel: meta-analysis. Int J Cardiol. 2013;167(3):965-74.
    • (2013) Int J Cardiol , vol.167 , Issue.3 , pp. 965-974
    • Kwok, C.S.1    Jeevanantham, V.2    Dawn, B.3    Loke, Y.K.4
  • 72
    • 78650011234 scopus 로고    scopus 로고
    • Risk of recurrent myocardial infarction with the concomitant use of clopidogrel and proton pump inhibitors
    • Valkhoff VE, Jong GW, Van Soest EM, Kuipers EJ, Sturkenboom MC. Risk of recurrent myocardial infarction with the concomitant use of clopidogrel and proton pump inhibitors. Aliment Pharmacol Ther. 2011;33(1):77-88.
    • (2011) Aliment Pharmacol Ther. , vol.33 , Issue.1 , pp. 77-88
    • Valkhoff, V.E.1    Jong, G.W.2    Van Soest, E.M.3    Kuipers, E.J.4    Sturkenboom, M.C.5
  • 73
    • 79956336197 scopus 로고    scopus 로고
    • Proton pump inhibitor use and risk of adverse cardiovascular events in aspirin treated patients with first time myocardial infarction: Nationwide propensity score matched study
    • 3092520 21562004
    • Charlot M, Grove EL, Hansen PR, Olesen JB, Ahlehoff O, Selmer C, et al. Proton pump inhibitor use and risk of adverse cardiovascular events in aspirin treated patients with first time myocardial infarction: nationwide propensity score matched study. BMJ. 2011;342:d2690.
    • (2011) BMJ , vol.342 , pp. 2690
    • Charlot, M.1    Grove, E.L.2    Hansen, P.R.3    Olesen, J.B.4    Ahlehoff, O.5    Selmer, C.6
  • 74
    • 77649210337 scopus 로고    scopus 로고
    • The antiplatelet effect of aspirin is reduced by proton pump inhibitors in patients with coronary artery disease
    • 19910291
    • Wurtz M, Grove EL, Kristensen SD, Hvas AM. The antiplatelet effect of aspirin is reduced by proton pump inhibitors in patients with coronary artery disease. Heart. 2010;96(5):368-71.
    • (2010) Heart , vol.96 , Issue.5 , pp. 368-371
    • Wurtz, M.1    Grove, E.L.2    Kristensen, S.D.3    Hvas, A.M.4
  • 76
    • 84891845021 scopus 로고    scopus 로고
    • Use of proton pump inhibitors and the risk of coronary events in new users of low-dose acetylsalicylic acid in UK primary care
    • 24153412
    • Garcia Rodriguez LA, Johansson S, Nagy P, Cea Soriano L. Use of proton pump inhibitors and the risk of coronary events in new users of low-dose acetylsalicylic acid in UK primary care. Thromb Haemost. 2014;111(1):131-9.
    • (2014) Thromb Haemost , vol.111 , Issue.1 , pp. 131-139
    • Garcia Rodriguez, L.A.1    Johansson, S.2    Nagy, P.3    Cea Soriano, L.4
  • 77
    • 0018400336 scopus 로고
    • Malabsorption of thyroid hormones after jejunoileal bypass for obesity
    • 443690
    • Azizi F, Belur R, Albano J. Malabsorption of thyroid hormones after jejunoileal bypass for obesity. Ann Intern Med. 1979;90(6):941-2.
    • (1979) Ann Intern Med , vol.90 , Issue.6 , pp. 941-942
    • Azizi, F.1    Belur, R.2    Albano, J.3
  • 79
    • 71749087074 scopus 로고    scopus 로고
    • Conditions and drugs interfering with thyroxine absorption
    • 19942153
    • Liwanpo L, Hershman JM. Conditions and drugs interfering with thyroxine absorption. Best Pract Res Clin Endocrinol Metab. 2009;23(6):781-92.
    • (2009) Best Pract Res Clin Endocrinol Metab , vol.23 , Issue.6 , pp. 781-792
    • Liwanpo, L.1    Hershman, J.M.2
  • 80
    • 0034616763 scopus 로고    scopus 로고
    • Effect of calcium carbonate on the absorption of levothyroxine
    • 10838651
    • Singh N, Singh PN, Hershman JM. Effect of calcium carbonate on the absorption of levothyroxine. JAMA. 2000;283(21):2822-5.
    • (2000) JAMA , vol.283 , Issue.21 , pp. 2822-2825
    • Singh, N.1    Singh, P.N.2    Hershman, J.M.3
  • 81
    • 34548423165 scopus 로고    scopus 로고
    • Effect of proton pump inhibitors on serum thyroid-stimulating hormone level in euthyroid patients treated with levothyroxine for hypothyroidism
    • 17669709
    • Sachmechi I, Reich DM, Aninyei M, Wibowo F, Gupta G, Kim PJ. Effect of proton pump inhibitors on serum thyroid-stimulating hormone level in euthyroid patients treated with levothyroxine for hypothyroidism. Endocr Pract. 2007;13(4):345-9.
    • (2007) Endocr Pract , vol.13 , Issue.4 , pp. 345-349
    • Sachmechi, I.1    Reich, D.M.2    Aninyei, M.3    Wibowo, F.4    Gupta, G.5    Kim, P.J.6
  • 82
    • 33645703895 scopus 로고    scopus 로고
    • Absorption kinetics of levothyroxine is not altered by proton-pump inhibitor therapy
    • 16477543
    • Dietrich JW, Gieselbrecht K, Holl RW, Boehm BO. Absorption kinetics of levothyroxine is not altered by proton-pump inhibitor therapy. Horm Metab Res. 2006;38(1):57-9.
    • (2006) Horm Metab Res , vol.38 , Issue.1 , pp. 57-59
    • Dietrich, J.W.1    Gieselbrecht, K.2    Holl, R.W.3    Boehm, B.O.4
  • 83
    • 43449129176 scopus 로고    scopus 로고
    • The effect of famotidine, esomeprazole, and ezetimibe on levothyroxine absorption
    • 18466075
    • Ananthakrishnan S, Braverman LE, Levin RM, Magnani B, Pearce EN. The effect of famotidine, esomeprazole, and ezetimibe on levothyroxine absorption. Thyroid. 2008;18(5):493-8.
    • (2008) Thyroid , vol.18 , Issue.5 , pp. 493-498
    • Ananthakrishnan, S.1    Braverman, L.E.2    Levin, R.M.3    Magnani, B.4    Pearce, E.N.5
  • 84
    • 0020576587 scopus 로고
    • Serum T4, T3, and TSH levels in primary hypothyroidism during replacement therapy with thyroxine
    • 6865774
    • Brajkovich IE, Mashiter K, Joplin GF, Cassar J. Serum T4, T3, and TSH levels in primary hypothyroidism during replacement therapy with thyroxine. Metabolism. 1983;32(8):745-7.
    • (1983) Metabolism , vol.32 , Issue.8 , pp. 745-747
    • Brajkovich, I.E.1    Mashiter, K.2    Joplin, G.F.3    Cassar, J.4
  • 85
    • 84879941394 scopus 로고    scopus 로고
    • Short- and long-term mortality in males and females with fragility hip fracture in Norway. A population-based study
    • 3704300 23861581
    • Diamantopoulos AP, Hoff M, Skoie IM, Hochberg M, Haugeberg G. Short- and long-term mortality in males and females with fragility hip fracture in Norway. A population-based study. Clin Interv Aging. 2013;8:817-23.
    • (2013) Clin Interv Aging , vol.8 , pp. 817-823
    • Diamantopoulos, A.P.1    Hoff, M.2    Skoie, I.M.3    Hochberg, M.4    Haugeberg, G.5
  • 86
    • 50249170304 scopus 로고    scopus 로고
    • Mortality following hip fracture: Trends and geographical variations over the last 40 years
    • 18653186
    • Haleem S, Lutchman L, Mayahi R, Grice JE, Parker MJ. Mortality following hip fracture: trends and geographical variations over the last 40 years. Injury. 2008;39(10):1157-63.
    • (2008) Injury , vol.39 , Issue.10 , pp. 1157-1163
    • Haleem, S.1    Lutchman, L.2    Mayahi, R.3    Grice, J.E.4    Parker, M.J.5
  • 87
    • 84885019413 scopus 로고    scopus 로고
    • Continuous decline in incidence of hip fracture: Nationwide statistics from Finland between 1970 and 2010
    • 23108781
    • Korhonen N, Niemi S, Parkkari J, Sievanen H, Palvanen M, Kannus P. Continuous decline in incidence of hip fracture: nationwide statistics from Finland between 1970 and 2010. Osteoporos Int. 2013;24(5):1599-603.
    • (2013) Osteoporos Int , vol.24 , Issue.5 , pp. 1599-1603
    • Korhonen, N.1    Niemi, S.2    Parkkari, J.3    Sievanen, H.4    Palvanen, M.5    Kannus, P.6
  • 90
    • 0022636291 scopus 로고
    • Omeprazole, a specific inhibitor of H + -K + -ATPase, inhibits bone resorption in vitro
    • 3006888
    • Tuukkanen J, Vaananen HK. Omeprazole, a specific inhibitor of H + -K + -ATPase, inhibits bone resorption in vitro. Calcif Tissue Int. 1986;38(2):123-5.
    • (1986) Calcif Tissue Int , vol.38 , Issue.2 , pp. 123-125
    • Tuukkanen, J.1    Vaananen, H.K.2
  • 91
    • 0027207229 scopus 로고
    • Effect of omeprazole, an inhibitor of H+, K(+)-ATPase, on bone resorption in humans
    • 8102318
    • Mizunashi K, Furukawa Y, Katano K, Abe K. Effect of omeprazole, an inhibitor of H+, K(+)-ATPase, on bone resorption in humans. Calcif Tissue Int. 1993;53(1):21-5.
    • (1993) Calcif Tissue Int , vol.53 , Issue.1 , pp. 21-25
    • Mizunashi, K.1    Furukawa, Y.2    Katano, K.3    Abe, K.4
  • 92
    • 0034095006 scopus 로고    scopus 로고
    • Low fractional calcium absorption increases the risk for hip fracture in women with low calcium intake. Study of Osteoporotic Fractures Research Group
    • 10691584
    • Ensrud KE, Duong T, Cauley JA, Heaney RP, Wolf RL, Harris E, et al. Low fractional calcium absorption increases the risk for hip fracture in women with low calcium intake. Study of Osteoporotic Fractures Research Group. Ann Intern Med. 2000;132(5):345-53.
    • (2000) Ann Intern Med , vol.132 , Issue.5 , pp. 345-353
    • Ensrud, K.E.1    Duong, T.2    Cauley, J.A.3    Heaney, R.P.4    Wolf, R.L.5    Harris, E.6
  • 93
    • 21244436672 scopus 로고    scopus 로고
    • Effects of proton pump inhibitors on calcium carbonate absorption in women: A randomized crossover trial
    • 15989913
    • O'Connell MB, Madden DM, Murray AM, Heaney RP, Kerzner LJ. Effects of proton pump inhibitors on calcium carbonate absorption in women: a randomized crossover trial. Am J Med. 2005;118(7):778-81.
    • (2005) Am J Med , vol.118 , Issue.7 , pp. 778-781
    • O'Connell, M.B.1    Madden, D.M.2    Murray, A.M.3    Heaney, R.P.4    Kerzner, L.J.5
  • 94
    • 84870534648 scopus 로고    scopus 로고
    • Chronic proton pump inhibitor therapy and calcium metabolism
    • 23054811
    • Yang YX. Chronic proton pump inhibitor therapy and calcium metabolism. Curr Gastroenterol Rep. 2012;14(6):473-9.
    • (2012) Curr Gastroenterol Rep , vol.14 , Issue.6 , pp. 473-479
    • Yang, Y.X.1
  • 95
    • 77249135057 scopus 로고    scopus 로고
    • Proton-pump inhibitor use is not associated with osteoporosis or accelerated bone mineral density loss
    • 19931262
    • Targownik LE, Lix LM, Leung S, Leslie WD. Proton-pump inhibitor use is not associated with osteoporosis or accelerated bone mineral density loss. Gastroenterology. 2010;138(3):896-904.
    • (2010) Gastroenterology , vol.138 , Issue.3 , pp. 896-904
    • Targownik, L.E.1    Lix, L.M.2    Leung, S.3    Leslie, W.D.4
  • 96
    • 54349103932 scopus 로고    scopus 로고
    • Acid-suppressive medications and risk of bone loss and fracture in older adults
    • 2596870 18813868
    • Yu EW, Blackwell T, Ensrud KE, Hillier TA, Lane NE, Orwoll E, et al. Acid-suppressive medications and risk of bone loss and fracture in older adults. Calcif Tissue Int. 2008;83(4):251-9.
    • (2008) Calcif Tissue Int , vol.83 , Issue.4 , pp. 251-259
    • Yu, E.W.1    Blackwell, T.2    Ensrud, K.E.3    Hillier, T.A.4    Lane, N.E.5    Orwoll, E.6
  • 97
    • 58149279436 scopus 로고    scopus 로고
    • Increase in vertebral fracture risk in postmenopausal women using omeprazole
    • 19023510
    • Roux C, Briot K, Gossec L, Kolta S, Blenk T, Felsenberg D, et al. Increase in vertebral fracture risk in postmenopausal women using omeprazole. Calcif Tissue Int. 2009;84(1):13-9.
    • (2009) Calcif Tissue Int , vol.84 , Issue.1 , pp. 13-19
    • Roux, C.1    Briot, K.2    Gossec, L.3    Kolta, S.4    Blenk, T.5    Felsenberg, D.6
  • 98
    • 77952115101 scopus 로고    scopus 로고
    • Proton pump inhibitor use, hip fracture, and change in bone mineral density in postmenopausal women: Results from the Women's Health Initiative
    • 20458083
    • Gray SL, LaCroix AZ, Larson J, Robbins J, Cauley JA, Manson JE, et al. Proton pump inhibitor use, hip fracture, and change in bone mineral density in postmenopausal women: results from the Women's Health Initiative. Arch Intern Med. 2010;170(9):765-71.
    • (2010) Arch Intern Med , vol.170 , Issue.9 , pp. 765-771
    • Gray, S.L.1    Lacroix, A.Z.2    Larson, J.3    Robbins, J.4    Cauley, J.A.5    Manson, J.E.6
  • 99
    • 84857356457 scopus 로고    scopus 로고
    • Vertebral fracture efficacy during risedronate therapy in patients using proton pump inhibitors
    • 21365461
    • Roux C, Goldstein JL, Zhou X, Klemes A, Lindsay R. Vertebral fracture efficacy during risedronate therapy in patients using proton pump inhibitors. Osteoporos Int. 2012;23(1):277-84.
    • (2012) Osteoporos Int , vol.23 , Issue.1 , pp. 277-284
    • Roux, C.1    Goldstein, J.L.2    Zhou, X.3    Klemes, A.4    Lindsay, R.5
  • 100
    • 84883198093 scopus 로고    scopus 로고
    • Bone density in proton pump inhibitors users: A prospective study
    • 23455632
    • Ozdil K, Kahraman R, Sahin A, Calhan T, Gozden EH, Akyuz U, et al. Bone density in proton pump inhibitors users: a prospective study. Rheumatol Int. 2013;33(9):2255-60.
    • (2013) Rheumatol Int , vol.33 , Issue.9 , pp. 2255-2260
    • Ozdil, K.1    Kahraman, R.2    Sahin, A.3    Calhan, T.4    Gozden, E.H.5    Akyuz, U.6
  • 101
    • 84885825052 scopus 로고    scopus 로고
    • Use of proton pump inhibitors is associated with lower trabecular bone density in older individuals
    • 24076021
    • Maggio M, Lauretani F, Ceda GP, De Vita F, Bondi G, Corsonello A, et al. Use of proton pump inhibitors is associated with lower trabecular bone density in older individuals. Bone. 2013;57(2):437-42.
    • (2013) Bone , vol.57 , Issue.2 , pp. 437-442
    • Maggio, M.1    Lauretani, F.2    Ceda, G.P.3    De Vita, F.4    Bondi, G.5    Corsonello, A.6
  • 102
    • 84879884280 scopus 로고    scopus 로고
    • Risk factors for falls with use of acid-suppressive drugs
    • 23676267
    • Cea-Soriano L, Johansson S, Garcia Rodriguez LA. Risk factors for falls with use of acid-suppressive drugs. Epidemiology. 2013;24(4):600-7.
    • (2013) Epidemiology , vol.24 , Issue.4 , pp. 600-607
    • Cea-Soriano, L.1    Johansson, S.2    Garcia Rodriguez, L.A.3
  • 103
    • 33845864487 scopus 로고    scopus 로고
    • Long-term proton pump inhibitor therapy and risk of hip fracture
    • 17190895
    • Yang YX, Lewis JD, Epstein S, Metz DC. Long-term proton pump inhibitor therapy and risk of hip fracture. JAMA. 2006;296(24):2947-53.
    • (2006) JAMA , vol.296 , Issue.24 , pp. 2947-2953
    • Yang, Y.X.1    Lewis, J.D.2    Epstein, S.3    Metz, D.C.4
  • 104
    • 77953880651 scopus 로고    scopus 로고
    • Proton pump inhibitors and histamine-2 receptor antagonists are associated with hip fractures among at-risk patients
    • 2902649 20353792
    • Corley DA, Kubo A, Zhao W, Quesenberry C. Proton pump inhibitors and histamine-2 receptor antagonists are associated with hip fractures among at-risk patients. Gastroenterology. 2010;139(1):93-101.
    • (2010) Gastroenterology , vol.139 , Issue.1 , pp. 93-101
    • Corley, D.A.1    Kubo, A.2    Zhao, W.3    Quesenberry, C.4
  • 105
    • 49749141653 scopus 로고    scopus 로고
    • Use of proton pump inhibitors and risk of osteoporosis-related fractures
    • 2492962 18695179
    • Targownik LE, Lix LM, Metge CJ, Prior HJ, Leung S, Leslie WD. Use of proton pump inhibitors and risk of osteoporosis-related fractures. CMAJ. 2008;179(4):319-26.
    • (2008) CMAJ , vol.179 , Issue.4 , pp. 319-326
    • Targownik, L.E.1    Lix, L.M.2    Metge, C.J.3    Prior, H.J.4    Leung, S.5    Leslie, W.D.6
  • 106
    • 33748105475 scopus 로고    scopus 로고
    • Proton pump inhibitors, histamine H2 receptor antagonists, and other antacid medications and the risk of fracture
    • 16927047
    • Vestergaard P, Rejnmark L, Mosekilde L. Proton pump inhibitors, histamine H2 receptor antagonists, and other antacid medications and the risk of fracture. Calcif Tissue Int. 2006;79(2):76-83.
    • (2006) Calcif Tissue Int , vol.79 , Issue.2 , pp. 76-83
    • Vestergaard, P.1    Rejnmark, L.2    Mosekilde, L.3
  • 107
    • 79960055410 scopus 로고    scopus 로고
    • Proton pump inhibitors and risk of fracture: A systematic review and meta-analysis of observational studies
    • (quiz 19)
    • Ngamruengphong S, Leontiadis GI, Radhi S, Dentino A, Nugent K. Proton pump inhibitors and risk of fracture: a systematic review and meta-analysis of observational studies. Am J Gastroenterol. 2011;106(7):1209-18 (quiz 19).
    • (2011) Am J Gastroenterol. , vol.106 , Issue.7 , pp. 1209-1218
    • Ngamruengphong, S.1    Leontiadis, G.I.2    Radhi, S.3    Dentino, A.4    Nugent, K.5
  • 108
    • 61949298845 scopus 로고    scopus 로고
    • Proton pump inhibitors and bone fractures?
    • 19262543
    • Laine L. Proton pump inhibitors and bone fractures? Am J Gastroenterol. 2009;104(Suppl 2):S21-6.
    • (2009) Am J Gastroenterol , vol.104 , Issue.SUPPL. 2
    • Laine, L.1
  • 109
    • 79952704502 scopus 로고    scopus 로고
    • Meta-analysis: Risk of fractures with acid-suppressing medication
    • 21185417
    • Kwok CS, Yeong JK, Loke YK. Meta-analysis: risk of fractures with acid-suppressing medication. Bone. 2011;48(4):768-76.
    • (2011) Bone , vol.48 , Issue.4 , pp. 768-776
    • Kwok, C.S.1    Yeong, J.K.2    Loke, Y.K.3
  • 111
    • 84885603176 scopus 로고    scopus 로고
    • Canadian Association of Gastroenterology position statement: Hip fracture and proton pump inhibitor therapy - A 2013 update
    • Affairs obotCC 24251323
    • Moayyedi P, Yuan Y, Leontiadis G, Affairs obotCC. Canadian Association of Gastroenterology position statement: hip fracture and proton pump inhibitor therapy - a 2013 update. Can J Gastroenterol. 2013;27(10):593-5.
    • (2013) Can J Gastroenterol , vol.27 , Issue.10 , pp. 593-595
    • Moayyedi, P.1    Yuan, Y.2    Leontiadis, G.3
  • 112
    • 0027456324 scopus 로고
    • Gastroduodenal dysfunction and bacterial colonisation of the ventilated lung
    • 8096263
    • Inglis TJ, Sherratt MJ, Sproat LJ, Gibson JS, Hawkey PM. Gastroduodenal dysfunction and bacterial colonisation of the ventilated lung. Lancet. 1993;341(8850):911-3.
    • (1993) Lancet , vol.341 , Issue.8850 , pp. 911-913
    • Inglis, T.J.1    Sherratt, M.J.2    Sproat, L.J.3    Gibson, J.S.4    Hawkey, P.M.5
  • 113
    • 0025860320 scopus 로고
    • Role of gastric colonization in the development of pneumonia in critically ill trauma patients: Results of a prospective randomized trial
    • (discussion 6-7)
    • Simms HH, DeMaria E, McDonald L, Peterson D, Robinson A, Burchard KW. Role of gastric colonization in the development of pneumonia in critically ill trauma patients: results of a prospective randomized trial. J Trauma. 1991;31(4):531-6 (discussion 6-7).
    • (1991) J Trauma. , vol.31 , Issue.4 , pp. 531-536
    • Simms, H.H.1    Demaria, E.2    McDonald, L.3    Peterson, D.4    Robinson, A.5    Burchard, K.W.6
  • 115
    • 79951983392 scopus 로고    scopus 로고
    • Use of acid-suppressive drugs and risk of pneumonia: A systematic review and meta-analysis
    • 3042441 21173070
    • Eom CS, Jeon CY, Lim JW, Cho EG, Park SM, Lee KS. Use of acid-suppressive drugs and risk of pneumonia: a systematic review and meta-analysis. CMAJ. 2011;183(3):310-9.
    • (2011) CMAJ , vol.183 , Issue.3 , pp. 310-319
    • Eom, C.S.1    Jeon, C.Y.2    Lim, J.W.3    Cho, E.G.4    Park, S.M.5    Lee, K.S.6
  • 116
    • 0030768825 scopus 로고    scopus 로고
    • Comorbid occurrence of laryngeal or pulmonary disease with esophagitis in United States military veterans
    • el-Serag HB, Sonnenberg A. Comorbid occurrence of laryngeal or pulmonary disease with esophagitis in United States military veterans. Gastroenterology. 1997;113(3):755-60.
    • (1997) Gastroenterology. , vol.113 , Issue.3 , pp. 755-760
    • El-Serag, H.B.1    Sonnenberg, A.2
  • 117
    • 84895479775 scopus 로고    scopus 로고
    • Proton pump inhibitors and the risk of hospitalisation for community-acquired pneumonia: Replicated cohort studies with meta-analysis
    • Filion KB, Chateu D, Targownik LE, Gershon A, Duran M, Tamim H, et al. Proton pump inhibitors and the risk of hospitalisation for community-acquired pneumonia: replicated cohort studies with meta-analysis. Gut. 2014;63(4):552-8.
    • (2014) Gut. , vol.63 , Issue.4 , pp. 552-558
    • Filion, K.B.1    Chateu, D.2    Targownik, L.E.3    Gershon, A.4    Duran, M.5    Tamim, H.6
  • 118
    • 34248522811 scopus 로고    scopus 로고
    • Use of proton pump inhibitors and the risk of community-acquired pneumonia: A population-based case-control study
    • 17502537
    • Gulmez SE, Holm A, Frederiksen H, Jensen TG, Pedersen C, Hallas J. Use of proton pump inhibitors and the risk of community-acquired pneumonia: a population-based case-control study. Arch Intern Med. 2007;167(9):950-5.
    • (2007) Arch Intern Med , vol.167 , Issue.9 , pp. 950-955
    • Gulmez, S.E.1    Holm, A.2    Frederiksen, H.3    Jensen, T.G.4    Pedersen, C.5    Hallas, J.6
  • 119
    • 51949090295 scopus 로고    scopus 로고
    • Proton-pump inhibitor use and the risk for community-acquired pneumonia
    • 18794558
    • Sarkar M, Hennessy S, Yang YX. Proton-pump inhibitor use and the risk for community-acquired pneumonia. Ann Intern Med. 2008;149(6):391-8.
    • (2008) Ann Intern Med , vol.149 , Issue.6 , pp. 391-398
    • Sarkar, M.1    Hennessy, S.2    Yang, Y.X.3
  • 120
    • 0029778380 scopus 로고    scopus 로고
    • Stomach as a source of colonization of the respiratory tract during mechanical ventilation: Association with ventilator-associated pneumonia
    • 8866601
    • Torres A, El-Ebiary M, Soler N, Monton C, Fabregas N, Hernandez C. Stomach as a source of colonization of the respiratory tract during mechanical ventilation: association with ventilator-associated pneumonia. Eur Respir J. 1996;9(8):1729-35.
    • (1996) Eur Respir J , vol.9 , Issue.8 , pp. 1729-1735
    • Torres, A.1    El-Ebiary, M.2    Soler, N.3    Monton, C.4    Fabregas, N.5    Hernandez, C.6
  • 121
    • 0030031642 scopus 로고    scopus 로고
    • Prognosis and outcomes of patients with community-acquired pneumonia. A meta-analysis
    • 8531309
    • Fine MJ, Smith MA, Carson CA, Mutha SS, Sankey SS, Weissfeld LA, et al. Prognosis and outcomes of patients with community-acquired pneumonia. A meta-analysis. JAMA. 1996;275(2):134-41.
    • (1996) JAMA , vol.275 , Issue.2 , pp. 134-141
    • Fine, M.J.1    Smith, M.A.2    Carson, C.A.3    Mutha, S.S.4    Sankey, S.S.5    Weissfeld, L.A.6
  • 122
    • 84872061155 scopus 로고    scopus 로고
    • Clinical practice. Vitamin B12 deficiency
    • 23301732
    • Stabler SP. Clinical practice. Vitamin B12 deficiency. N Engl J Med. 2013;368(2):149-60.
    • (2013) N Engl J Med , vol.368 , Issue.2 , pp. 149-160
    • Stabler, S.P.1
  • 123
    • 0022632122 scopus 로고
    • Megaloblastic anaemia due to vitamin B12 deficiency caused by small intestinal bacterial overgrowth: Possible role of vitamin B12 analogues
    • 3942698
    • Murphy MF, Sourial NA, Burman JF, Doyle DV, Tabaqchali S, Mollin DL. Megaloblastic anaemia due to vitamin B12 deficiency caused by small intestinal bacterial overgrowth: possible role of vitamin B12 analogues. Br J Haematol. 1986;62(1):7-12.
    • (1986) Br J Haematol , vol.62 , Issue.1 , pp. 7-12
    • Murphy, M.F.1    Sourial, N.A.2    Burman, J.F.3    Doyle, D.V.4    Tabaqchali, S.5    Mollin, D.L.6
  • 124
    • 0018855218 scopus 로고
    • Toskes PP. Malabsorption of protein-bound cobalamin but not unbound cobalamin during cimetidine administration
    • 6768534
    • Steinberg WM, King CE. Toskes PP. Malabsorption of protein-bound cobalamin but not unbound cobalamin during cimetidine administration. Dig Dis Sci. 1980;25(3):188-91.
    • (1980) Dig Dis Sci , vol.25 , Issue.3 , pp. 188-191
    • Steinberg, W.M.1    King, C.E.2
  • 125
    • 0028178495 scopus 로고
    • Omeprazole therapy causes malabsorption of cyanocobalamin (vitamin B12)
    • 8273984
    • Marcuard SP, Albernaz L, Khazanie PG. Omeprazole therapy causes malabsorption of cyanocobalamin (vitamin B12). Ann Intern Med. 1994;120(3):211-5.
    • (1994) Ann Intern Med , vol.120 , Issue.3 , pp. 211-215
    • Marcuard, S.P.1    Albernaz, L.2    Khazanie, P.G.3
  • 126
    • 0027942276 scopus 로고
    • Effect of hypochlorhydria due to omeprazole treatment or atrophic gastritis on protein-bound vitamin B12 absorption
    • 7706591
    • Saltzman JR, Kemp JA, Golner BB, Pedrosa MC, Dallal GE, Russell RM. Effect of hypochlorhydria due to omeprazole treatment or atrophic gastritis on protein-bound vitamin B12 absorption. J Am Coll Nutr. 1994;13(6):584-91.
    • (1994) J Am Coll Nutr , vol.13 , Issue.6 , pp. 584-591
    • Saltzman, J.R.1    Kemp, J.A.2    Golner, B.B.3    Pedrosa, M.C.4    Dallal, G.E.5    Russell, R.M.6
  • 127
    • 0030016789 scopus 로고    scopus 로고
    • Effect of short- and long-term treatment with omeprazole on the absorption and serum levels of cobalamin
    • 8853757
    • Schenk BE, Festen HP, Kuipers EJ, Klinkenberg-Knol EC, Meuwissen SG. Effect of short- and long-term treatment with omeprazole on the absorption and serum levels of cobalamin. Aliment Pharmacol Ther. 1996;10(4):541-5.
    • (1996) Aliment Pharmacol Ther , vol.10 , Issue.4 , pp. 541-545
    • Schenk, B.E.1    Festen, H.P.2    Kuipers, E.J.3    Klinkenberg-Knol, E.C.4    Meuwissen, S.G.5
  • 128
    • 0032076634 scopus 로고    scopus 로고
    • Effect of long-term gastric acid suppressive therapy on serum vitamin B12 levels in patients with Zollinger-Ellison syndrome
    • 9626024
    • Termanini B, Gibril F, Sutliff VE, Yu F, Venzon DJ, Jensen RT. Effect of long-term gastric acid suppressive therapy on serum vitamin B12 levels in patients with Zollinger-Ellison syndrome. Am J Med. 1998;104(5):422-30.
    • (1998) Am J Med , vol.104 , Issue.5 , pp. 422-430
    • Termanini, B.1    Gibril, F.2    Sutliff, V.E.3    Yu, F.4    Venzon, D.J.5    Jensen, R.T.6
  • 129
    • 2342539011 scopus 로고    scopus 로고
    • A case-control study on adverse effects: H2 blocker or proton pump inhibitor use and risk of vitamin B12 deficiency in older adults
    • 15135846
    • Valuck RJ, Ruscin JM. A case-control study on adverse effects: H2 blocker or proton pump inhibitor use and risk of vitamin B12 deficiency in older adults. J Clin Epidemiol. 2004;57(4):422-8.
    • (2004) J Clin Epidemiol , vol.57 , Issue.4 , pp. 422-428
    • Valuck, R.J.1    Ruscin, J.M.2
  • 133
    • 0028295618 scopus 로고
    • Helicobacter pylori infection and food-cobalamin malabsorption
    • 8313813
    • Carmel R, Perez-Perez GI, Blaser MJ. Helicobacter pylori infection and food-cobalamin malabsorption. Dig Dis Sci. 1994;39(2):309-14.
    • (1994) Dig Dis Sci , vol.39 , Issue.2 , pp. 309-314
    • Carmel, R.1    Perez-Perez, G.I.2    Blaser, M.J.3
  • 135
    • 0032917214 scopus 로고    scopus 로고
    • Effect of CYP2C19 polymorphism on serum levels of vitamin B12 in patients on long-term omeprazole treatment
    • 10215728
    • Sagar M, Janczewska I, Ljungdahl A, Bertilsson L, Seensalu R. Effect of CYP2C19 polymorphism on serum levels of vitamin B12 in patients on long-term omeprazole treatment. Aliment Pharmacol Ther. 1999;13(4):453-8.
    • (1999) Aliment Pharmacol Ther , vol.13 , Issue.4 , pp. 453-458
    • Sagar, M.1    Janczewska, I.2    Ljungdahl, A.3    Bertilsson, L.4    Seensalu, R.5
  • 136
    • 0033621622 scopus 로고    scopus 로고
    • Cobalamin (Vitamin B12) deficiency: Is it a problem for our aging population and is the problem compounded by drugs that inhibit gastric acid secretion?
    • 10636204
    • Kapadia C. Cobalamin (Vitamin B12) deficiency: is it a problem for our aging population and is the problem compounded by drugs that inhibit gastric acid secretion? J Clin Gastroenterol. 2000;30(1):4-6.
    • (2000) J Clin Gastroenterol , vol.30 , Issue.1 , pp. 4-6
    • Kapadia, C.1
  • 137
    • 0033621625 scopus 로고    scopus 로고
    • Vitamin B12 levels during prolonged treatment with proton pump inhibitors
    • 10636207
    • Howden CW. Vitamin B12 levels during prolonged treatment with proton pump inhibitors. J Clin Gastroenterol. 2000;30(1):29-33.
    • (2000) J Clin Gastroenterol , vol.30 , Issue.1 , pp. 29-33
    • Howden, C.W.1
  • 138
    • 0014431181 scopus 로고
    • Effect of hydrochloric acid on iron absorption
    • 5670905
    • Schade SG, Cohen RJ, Conrad ME. Effect of hydrochloric acid on iron absorption. N Engl J Med. 1968;279(13):672-4.
    • (1968) N Engl J Med , vol.279 , Issue.13 , pp. 672-674
    • Schade, S.G.1    Cohen, R.J.2    Conrad, M.E.3
  • 139
    • 0017881954 scopus 로고
    • The importance of gastric hydrochloric acid in the absorption of nonheme food iron
    • 26726
    • Bezwoda W, Charlton R, Bothwell T, Torrance J, Mayet F. The importance of gastric hydrochloric acid in the absorption of nonheme food iron. J Lab Clin Med. 1978;92(1):108-16.
    • (1978) J Lab Clin Med , vol.92 , Issue.1 , pp. 108-116
    • Bezwoda, W.1    Charlton, R.2    Bothwell, T.3    Torrance, J.4    Mayet, F.5
  • 140
    • 0031963940 scopus 로고    scopus 로고
    • Iron absorption in patients with Zollinger-Ellison syndrome treated with long-term gastric acid antisecretory therapy
    • 9692706
    • Stewart CA, Termanini B, Sutliff VE, Serrano J, Yu F, Gibril F, et al. Iron absorption in patients with Zollinger-Ellison syndrome treated with long-term gastric acid antisecretory therapy. Aliment Pharmacol Ther. 1998;12(1):83-98.
    • (1998) Aliment Pharmacol Ther , vol.12 , Issue.1 , pp. 83-98
    • Stewart, C.A.1    Termanini, B.2    Sutliff, V.E.3    Serrano, J.4    Yu, F.5    Gibril, F.6
  • 141
    • 34548127058 scopus 로고    scopus 로고
    • Proton pump inhibitors suppress absorption of dietary non-haem iron in hereditary haemochromatosis
    • 1954964 17344278
    • Hutchinson C, Geissler CA, Powell JJ, Bomford A. Proton pump inhibitors suppress absorption of dietary non-haem iron in hereditary haemochromatosis. Gut. 2007;56(9):1291-5.
    • (2007) Gut , vol.56 , Issue.9 , pp. 1291-1295
    • Hutchinson, C.1    Geissler, C.A.2    Powell, J.J.3    Bomford, A.4
  • 143
    • 55649119326 scopus 로고    scopus 로고
    • Update of nutrient-deficiency anemia in elderly patients
    • 19013375
    • Andres E, Federici L, Serraj K, Kaltenbach G. Update of nutrient-deficiency anemia in elderly patients. Eur J Intern Med. 2008;19(7):488-93.
    • (2008) Eur J Intern Med , vol.19 , Issue.7 , pp. 488-493
    • Andres, E.1    Federici, L.2    Serraj, K.3    Kaltenbach, G.4
  • 144
    • 39749155668 scopus 로고    scopus 로고
    • Prevalence of anaemia in older persons: Systematic review
    • 2248585 18194534
    • Gaskell H, Derry S, Andrew Moore R, McQuay HJ. Prevalence of anaemia in older persons: systematic review. BMC Geriatr. 2008;8:1.
    • (2008) BMC Geriatr , vol.8 , pp. 1
    • Gaskell, H.1    Derry, S.2    Andrew Moore, R.3    McQuay, H.J.4
  • 145
    • 77954821992 scopus 로고    scopus 로고
    • Infectious diarrhea: Cellular and molecular mechanisms
    • 3035144 21327112
    • Hodges K, Gill R. Infectious diarrhea: cellular and molecular mechanisms. Gut Microbes. 2010;1(1):4-21.
    • (2010) Gut Microbes , vol.1 , Issue.1 , pp. 4-21
    • Hodges, K.1    Gill, R.2
  • 146
    • 43049115384 scopus 로고    scopus 로고
    • Clostridium difficile infection
    • 18456087
    • Kuipers EJ, Surawicz CM. Clostridium difficile infection. Lancet. 2008;371(9623):1486-8.
    • (2008) Lancet , vol.371 , Issue.9623 , pp. 1486-1488
    • Kuipers, E.J.1    Surawicz, C.M.2
  • 147
    • 60549117587 scopus 로고    scopus 로고
    • Health care-associated Clostridium difficile infection in adults admitted to acute care hospitals in Canada: A Canadian Nosocomial Infection Surveillance Program Study
    • 19191641
    • Gravel D, Miller M, Simor A, Taylor G, Gardam M, McGeer A, et al. Health care-associated Clostridium difficile infection in adults admitted to acute care hospitals in Canada: a Canadian Nosocomial Infection Surveillance Program Study. Clin Infect Dis. 2009;48(5):568-76.
    • (2009) Clin Infect Dis , vol.48 , Issue.5 , pp. 568-576
    • Gravel, D.1    Miller, M.2    Simor, A.3    Taylor, G.4    Gardam, M.5    McGeer, A.6
  • 148
    • 28844441314 scopus 로고    scopus 로고
    • A predominantly clonal multi-institutional outbreak of Clostridium difficile-associated diarrhea with high morbidity and mortality
    • 16322602
    • Loo VG, Poirier L, Miller MA, Oughton M, Libman MD, Michaud S, et al. A predominantly clonal multi-institutional outbreak of Clostridium difficile-associated diarrhea with high morbidity and mortality. N Engl J Med. 2005;353(23):2442-9.
    • (2005) N Engl J Med , vol.353 , Issue.23 , pp. 2442-2449
    • Loo, V.G.1    Poirier, L.2    Miller, M.A.3    Oughton, M.4    Libman, M.D.5    Michaud, S.6
  • 149
    • 84876711968 scopus 로고    scopus 로고
    • Proton pump inhibitor use and the risk of small intestinal bacterial overgrowth: A meta-analysis
    • 23270866
    • Lo WK, Chan WW. Proton pump inhibitor use and the risk of small intestinal bacterial overgrowth: a meta-analysis. Clin Gastroenterol Hepatol. 2013;11(5):483-90.
    • (2013) Clin Gastroenterol Hepatol , vol.11 , Issue.5 , pp. 483-490
    • Lo, W.K.1    Chan, W.W.2
  • 151
    • 34548142191 scopus 로고    scopus 로고
    • Systematic review of the risk of enteric infection in patients taking acid suppression
    • (quiz 57)
    • Leonard J, Marshall JK, Moayyedi P. Systematic review of the risk of enteric infection in patients taking acid suppression. Am J Gastroenterol. 2007;102(9):2047-56 (quiz 57).
    • (2007) Am J Gastroenterol. , vol.102 , Issue.9 , pp. 2047-2056
    • Leonard, J.1    Marshall, J.K.2    Moayyedi, P.3
  • 152
    • 84863726088 scopus 로고    scopus 로고
    • Clostridium difficile-associated diarrhea and proton pump inhibitor therapy: A meta-analysis
    • 22710578
    • Janarthanan S, Ditah I, Adler DG, Ehrinpreis MN. Clostridium difficile-associated diarrhea and proton pump inhibitor therapy: a meta-analysis. Am J Gastroenterol. 2012;107(7):1001-10.
    • (2012) Am J Gastroenterol , vol.107 , Issue.7 , pp. 1001-1010
    • Janarthanan, S.1    Ditah, I.2    Adler, D.G.3    Ehrinpreis, M.N.4
  • 153
    • 84863717616 scopus 로고    scopus 로고
    • Risk of Clostridium difficile infection with acid suppressing drugs and antibiotics: Meta-analysis
    • 22525304
    • Kwok CS, Arthur AK, Anibueze CI, Singh S, Cavallazzi R, Loke YK. Risk of Clostridium difficile infection with acid suppressing drugs and antibiotics: meta-analysis. Am J Gastroenterol. 2012;107(7):1011-9.
    • (2012) Am J Gastroenterol , vol.107 , Issue.7 , pp. 1011-1019
    • Kwok, C.S.1    Arthur, A.K.2    Anibueze, C.I.3    Singh, S.4    Cavallazzi, R.5    Loke, Y.K.6
  • 154
  • 155
    • 0015319397 scopus 로고
    • Gastric acid barrier to ingested microorganisms in man: Studies in vivo and in vitro
    • 1412163 4556018
    • Giannella RA, Broitman SA, Zamcheck N. Gastric acid barrier to ingested microorganisms in man: studies in vivo and in vitro. Gut. 1972;13(4):251-6.
    • (1972) Gut , vol.13 , Issue.4 , pp. 251-256
    • Giannella, R.A.1    Broitman, S.A.2    Zamcheck, N.3
  • 156
    • 33646156654 scopus 로고    scopus 로고
    • Risk factors for Salmonella enteritidis and typhimurium (DT104 and non-DT104) infections in the Netherlands: Predominant roles for raw eggs in Enteritidis and sandboxes in typhimurium infections
    • 2870426 16638166
    • Doorduyn Y, Van Den Brandhof WE, Van Duynhoven YT, Wannet WJ, Van Pelt W. Risk factors for Salmonella enteritidis and typhimurium (DT104 and non-DT104) infections in The Netherlands: predominant roles for raw eggs in Enteritidis and sandboxes in typhimurium infections. Epidemiol Infect. 2006;134(3):617-26.
    • (2006) Epidemiol Infect , vol.134 , Issue.3 , pp. 617-626
    • Doorduyn, Y.1    Van Den Brandhof, W.E.2    Van Duynhoven, Y.T.3    Wannet, W.J.4    Van Pelt, W.5
  • 157
    • 48249157856 scopus 로고    scopus 로고
    • Novel insight in the association between salmonellosis or campylobacteriosis and chronic illness, and the role of host genetics in susceptibility to these diseases
    • 2870923 18062835
    • Doorduyn Y, Van Pelt W, Siezen CL, Van Der Horst F, Van Duynhoven YT, Hoebee B, et al. Novel insight in the association between salmonellosis or campylobacteriosis and chronic illness, and the role of host genetics in susceptibility to these diseases. Epidemiol Infect. 2008;136(9):1225-34.
    • (2008) Epidemiol Infect , vol.136 , Issue.9 , pp. 1225-1234
    • Doorduyn, Y.1    Van Pelt, W.2    Siezen, C.L.3    Van Der Horst, F.4    Van Duynhoven, Y.T.5    Hoebee, B.6
  • 158
    • 36549010841 scopus 로고    scopus 로고
    • Use of acid-suppressing drugs and the risk of bacterial gastroenteritis
    • 18054750
    • Garcia Rodriguez LA, Ruigomez A, Panes J. Use of acid-suppressing drugs and the risk of bacterial gastroenteritis. Clin Gastroenterol Hepatol. 2007;5(12):1418-23.
    • (2007) Clin Gastroenterol Hepatol , vol.5 , Issue.12 , pp. 1418-1423
    • Garcia Rodriguez, L.A.1    Ruigomez, A.2    Panes, J.3
  • 159
    • 33750320388 scopus 로고    scopus 로고
    • Proton-pump inhibitors and hypomagnesemic hypoparathyroidism
    • 17065651
    • Epstein M, McGrath S, Law F. Proton-pump inhibitors and hypomagnesemic hypoparathyroidism. N Engl J Med. 2006;355(17):1834-6.
    • (2006) N Engl J Med , vol.355 , Issue.17 , pp. 1834-1836
    • Epstein, M.1    McGrath, S.2    Law, F.3
  • 160
    • 66449111985 scopus 로고    scopus 로고
    • Hypomagnesaemia due to use of proton pump inhibitors-A review
    • 19581665
    • Kuipers MT, Thang HD, Arntzenius AB. Hypomagnesaemia due to use of proton pump inhibitors-a review. Neth J Med. 2009;67(5):169-72.
    • (2009) Neth J Med , vol.67 , Issue.5 , pp. 169-172
    • Kuipers, M.T.1    Thang, H.D.2    Arntzenius, A.B.3
  • 166
    • 0029156271 scopus 로고
    • Hypochlorhydria from short-term omeprazole treatment does not inhibit intestinal absorption of calcium, phosphorus, magnesium or zinc from food in humans
    • 8568113
    • Serfaty-Lacrosniere C, Wood RJ, Voytko D, Saltzman JR, Pedrosa M, Sepe TE, et al. Hypochlorhydria from short-term omeprazole treatment does not inhibit intestinal absorption of calcium, phosphorus, magnesium or zinc from food in humans. J Am Coll Nutr. 1995;14(4):364-8.
    • (1995) J Am Coll Nutr , vol.14 , Issue.4 , pp. 364-368
    • Serfaty-Lacrosniere, C.1    Wood, R.J.2    Voytko, D.3    Saltzman, J.R.4    Pedrosa, M.5    Sepe, T.E.6
  • 167
    • 0026285475 scopus 로고
    • Renal magnesium wasting associated with therapeutic agents
    • 1722865
    • Shah GM, Kirschenbaum MA. Renal magnesium wasting associated with therapeutic agents. Miner Electrolyte Metab. 1991;17(1):58-64.
    • (1991) Miner Electrolyte Metab , vol.17 , Issue.1 , pp. 58-64
    • Shah, G.M.1    Kirschenbaum, M.A.2
  • 168
    • 77955086666 scopus 로고    scopus 로고
    • Drug-induced acute interstitial nephritis
    • 20517290
    • Perazella MA, Markowitz GS. Drug-induced acute interstitial nephritis. Nat Rev Nephrol. 2010;6(8):461-70.
    • (2010) Nat Rev Nephrol , vol.6 , Issue.8 , pp. 461-470
    • Perazella, M.A.1    Markowitz, G.S.2
  • 169
    • 34547442899 scopus 로고    scopus 로고
    • Systematic review: Proton pump inhibitor-associated acute interstitial nephritis
    • 17661758
    • Sierra F, Suarez M, Rey M, Vela MF. Systematic review: proton pump inhibitor-associated acute interstitial nephritis. Aliment Pharmacol Ther. 2007;26(4):545-53.
    • (2007) Aliment Pharmacol Ther , vol.26 , Issue.4 , pp. 545-553
    • Sierra, F.1    Suarez, M.2    Rey, M.3    Vela, M.F.4
  • 171
    • 77950634823 scopus 로고    scopus 로고
    • Omeprazole-induced acute interstitial nephritis is not related to CYP2C19 genotype or CYP2C19 phenotype
    • 2856052 20573087
    • Helsby NA, Lo WY, Simpson IJ, Voss DM, Logan KE, Searle M, et al. Omeprazole-induced acute interstitial nephritis is not related to CYP2C19 genotype or CYP2C19 phenotype. Br J Clin Pharmacol. 2010;69(5):516-9.
    • (2010) Br J Clin Pharmacol , vol.69 , Issue.5 , pp. 516-519
    • Helsby, N.A.1    Lo, W.Y.2    Simpson, I.J.3    Voss, D.M.4    Logan, K.E.5    Searle, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.