Development of five digits is controlled by a bipartite long-range cis-regulator

Development (Cambridge)

Volumn 141, Issue 8, 2014, Pages 1715-1725

  Lettice, Laura A ^a   Williamson, Iain ^a   Devenney, Paul S ^a   Kilanowski, Fiona ^a   Dorin, Julia ^a   Hill, Robert E ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Limb development; Long range regulation; Mouse; Sonic hedgehog; ZRS

Indexed keywords

REGULATOR PROTEIN; SONIC HEDGEHOG PROTEIN; SPACER DNA; UNCLASSIFIED DRUG; ZRS PROTEIN;

ANIMAL EXPERIMENT; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; GAIN OF FUNCTION MUTATION; GENE ACTIVITY; GENE LOCUS; LIMB BUD; LIMB DEVELOPMENT; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN; PHENOTYPE; POINT MUTATION; POLYDACTYLY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REPORTER GENE; STRUCTURE ACTIVITY RELATION; TETRAPLOIDY;

LIMB DEVELOPMENT; LONG-RANGE REGULATION; MOUSE; SONIC HEDGEHOG; ZRS;

ANIMALS; BASE SEQUENCE; CHROMOSOMES, MAMMALIAN; DNA MUTATIONAL ANALYSIS; EMBRYO, MAMMALIAN; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HINDLIMB; IN SITU HYBRIDIZATION, FLUORESCENCE; LIMB BUDS; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NUCLEIC ACID CONFORMATION; PHENOTYPE; POINT MUTATION; REGULATORY SEQUENCES, NUCLEIC ACID; SEQUENCE DELETION;

EID: 84898766379     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.095430     Document Type: Article

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