Functional evaluation and characterization of a newly developed silicone oil-free prefillable syringe system

Journal of Pharmaceutical Sciences

Volumn 103, Issue 5, 2014, Pages 1520-1528

  Yoshino, Keisuke ^a   Nakamura, Koji ^a   Yamashita, Arisa ^a   Abe, Yoshihiko ^a   Iwasaki, Kazuhiro ^a   Kanazawa, Yukie ^a   Funatsu, Kaori ^a   Yoshimoto, Tsuyoshi ^a   Suzuki, Shigeru ^a  

^a TERUMO CORPORATION   (Japan)

Author keywords

container closure integrity; gliding force; imaging analysis; particle size; physical stability; prefilled syringe; protein aggregation; silicone oil; stability; surface chemistry

Indexed keywords

DYE; POLYMER; SILICONE OIL; PROTEIN;

ARTICLE; BACTERIAL GROWTH; BIOMEDICAL TECHNOLOGY ASSESSMENT; CHEMICAL COMPOSITION; CONTAINER; DRUG FORMULATION; FORCE; FRICTION; IMAGE ANALYSIS; INFRARED SPECTROSCOPY; MATERIAL COATING; MICROBIAL CONTAMINATION; MOLECULAR STABILITY; PROTEIN AGGREGATION; RISK; SCANNING ELECTRON MICROSCOPY; SILICONE OIL FREE SYRINGE SYSTEM; SURFACE PROPERTY; SYRINGE; TEMPERATURE DEPENDENCE; X RAY PHOTOELECTRON SPECTROSCOPY; CHEMISTRY; DRUG STABILITY; MEDICINAL CHEMISTRY; PROCEDURES;

CHEMISTRY, PHARMACEUTICAL; DRUG STABILITY; PROTEINS; SILICONE OILS; SYRINGES;

EID: 84898712795     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.23945     Document Type: Article

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