-
1
-
-
84855929701
-
Systems cancer medicine: Towards realization of predictive, preventive, personalized and participatory (p4) medicine
-
Tian Q, Price ND, Hood L (2012) Systems cancer medicine: towards realization of predictive, preventive, personalized and participatory (P4) medicine. J Intern Med 271: 111-121.
-
(2012)
J Intern Med
, vol.271
, pp. 111-121
-
-
Tian, Q.1
Price, N.D.2
Hood, L.3
-
2
-
-
79955686865
-
Gene expression significance in personalized medicine of non-small-cell lung cancer and gene expression analyzing platforms
-
Zhang L, Yang H, Xu J (2011) Gene expression significance in personalized medicine of non-small-cell lung cancer and gene expression analyzing platforms. Curr Drug Metab 12: 455-459.
-
(2011)
Curr Drug Metab
, vol.12
, pp. 455-459
-
-
Zhang, L.1
Yang, H.2
Xu, J.3
-
3
-
-
84898639432
-
The challenges and hopes of personalized cancer medicine
-
Xian W, McKeon F (2011) The challenges and hopes of personalized cancer medicine. Genome Med 3: 22.
-
(2011)
Genome Med
, vol.3
, pp. 22
-
-
Xian, W.1
McKeon, F.2
-
4
-
-
79952943956
-
Molecular profiling of cancer-The future of personalized cancer medicine: A primer on cancer biology and the tools necessary to bring molecular testing to the clinic
-
Stricker T, Catenacci DV, Seiwert TY (2011) Molecular profiling of cancer-the future of personalized cancer medicine: a primer on cancer biology and the tools necessary to bring molecular testing to the clinic. Semin Oncol 38: 173-185.
-
(2011)
Semin Oncol
, vol.38
, pp. 173-185
-
-
Stricker, T.1
Catenacci, D.V.2
Seiwert, T.Y.3
-
5
-
-
0037093092
-
Imatinib induces hematologic and cytogenetic responses in patients with chronic myelogenous leukemia in myeloid blast crisis: Results of a phase II study
-
DOI 10.1182/blood.V99.10.3530
-
Sawyers CL, Hochhaus A, Feldman E, Goldman JM, Miller CB, et al. (2002) Imatinib induces hematologic and cytogenetic responses in patients with chronic myelogenous leukemia in myeloid blast crisis: results of a phase II study. Blood 99: 3530-3539. (Pubitemid 34534519)
-
(2002)
Blood
, vol.99
, Issue.10
, pp. 3530-3539
-
-
Sawyers, C.L.1
Hochhaus, A.2
Feldman, E.3
Goldman, J.M.4
Miller, C.B.5
Ottmann, O.G.6
Schiffer, C.A.7
Talpaz, M.8
Guilhot, F.9
Deininger, M.W.N.10
Fischer, T.11
O'Brien, S.G.12
Stone, R.M.13
Gambacorti-Passerini, C.B.14
Russell, N.H.15
Reiffers, J.J.16
Shea, T.C.17
Chapuis, B.18
Coutre, S.19
Tura, S.20
Morra, E.21
Larson, R.A.22
Saven, A.23
Peschel, C.24
Gratwohl, A.25
Mandelli, F.26
Ben-Am, M.27
Gathmann, I.28
Capdeville, R.29
Paquette, R.L.30
Druker, B.J.31
more..
-
6
-
-
0036179603
-
Trastuzumab: A review of its use in the treatment of metastatic breast cancer overexpressing HER2
-
McKeage K, Perry CM (2002) Trastuzumab: a review of its use in the treatment of metastatic breast cancer overexpressing HER2. Drugs 62: 209-243. (Pubitemid 34169431)
-
(2002)
Drugs
, vol.62
, Issue.1
, pp. 209-243
-
-
McKeage, K.1
Perry, C.M.2
-
8
-
-
84868115867
-
Clinical cancer genome and precision medicine
-
Roukos DH, Ku CS (2012) Clinical cancer genome and precision medicine. Ann Surg Oncol 19: 3646-3650.
-
(2012)
Ann Surg Oncol
, vol.19
, pp. 3646-3650
-
-
Roukos, D.H.1
Ku, C.S.2
-
9
-
-
79951906119
-
Pilot study using molecular profiling of patients' tumors to find potential targets and select treatments for their refractory cancers
-
Von Hoff DD, Stephenson JJ Jr, Rosen P, Loesch DM, Borad MJ, et al. (2010) Pilot study using molecular profiling of patients' tumors to find potential targets and select treatments for their refractory cancers. J Clin Oncol 28: 4877-4883.
-
(2010)
J Clin Oncol
, vol.28
, pp. 4877-4883
-
-
Von Hoff, D.D.1
Stephenson Jr., J.J.2
Rosen, P.3
Loesch, D.M.4
Borad, M.J.5
-
10
-
-
84869223443
-
Personalized medicine in a phase i clinical trials program: The md anderson cancer center initiative
-
Tsimberidou AM, Iskander NG, Hong DS, Wheler JJ, Falchook GS, et al. (2012) Personalized Medicine in a Phase I Clinical Trials Program:The MD Anderson Cancer Center Initiative. Clin Cancer Res.
-
(2012)
Clin Cancer Res
-
-
Tsimberidou, A.M.1
Iskander, N.G.2
Hong, D.S.3
Wheler, J.J.4
Falchook, G.S.5
-
11
-
-
84872585155
-
Genome and transcriptome sequencing in prospective metastatic triple-negative breast cancer uncovers therapeutic vulnerabilities
-
Craig DW, O'Shaughnessy JA, Kiefer JA, Aldrich J, Sinari S, et al. (2013) Genome and transcriptome sequencing in prospective metastatic triple-negative breast cancer uncovers therapeutic vulnerabilities. Mol Cancer Ther 12: 104-116.
-
(2013)
Mol Cancer Ther
, vol.12
, pp. 104-116
-
-
Craig, D.W.1
O'Shaughnessy, J.A.2
Kiefer, J.A.3
Aldrich, J.4
Sinari, S.5
-
12
-
-
77955293476
-
Evolution of an adenocarcinoma in response to selection by targeted kinase inhibitors
-
Jones SJ, Laskin J, Li YY, Griffith OL, An J, et al. (2010) Evolution of an adenocarcinoma in response to selection by targeted kinase inhibitors. Genome Biol 11: R82.
-
(2010)
Genome Biol
, vol.11
-
-
Jones, S.J.1
Laskin, J.2
Li, Y.Y.3
Griffith, O.L.4
An, J.5
-
13
-
-
84872777716
-
Molecular diagnostics and personalized medicine in oncology: Challenges and opportunities
-
Normanno N, Rachiglio AM, Roma C, Fenizia F, Esposito C, et al. (2012) Molecular diagnostics and personalized medicine in oncology: Challenges and opportunities. J Cell Biochem.
-
(2012)
J Cell Biochem
-
-
Normanno, N.1
Rachiglio, A.M.2
Roma, C.3
Fenizia, F.4
Esposito, C.5
-
14
-
-
38549112058
-
Translation of new cancer treatments from pet dogs to humans
-
DOI 10.1038/nrc2273, PII NRC2273
-
Paoloni M, Khanna C (2008) Translation of new cancer treatments from pet dogs to humans. Nat Rev Cancer 8: 147-156. (Pubitemid 351161319)
-
(2008)
Nature Reviews Cancer
, vol.8
, Issue.2
, pp. 147-156
-
-
Paoloni, M.1
Khanna, C.2
-
15
-
-
0033671255
-
Spontaneously occurring tumors of companion animals as models for human cancer
-
Vail DM, MacEwen EG (2000) Spontaneously occurring tumors of companion animals as models for human cancer. Cancer Invest 18: 781-792.
-
(2000)
Cancer Invest
, vol.18
, pp. 781-792
-
-
Vail, D.M.1
MacEwen, E.G.2
-
16
-
-
33748516371
-
The dog as a cancer model
-
Khanna C, Lindblad-Toh K, Vail D, London C, Bergman P, et al. (2006) The dog as a cancer model. Nat Biotechnol 24: 1065-1066.
-
(2006)
Nat Biotechnol
, vol.24
, pp. 1065-1066
-
-
Khanna, C.1
Lindblad-Toh, K.2
Vail, D.3
London, C.4
Bergman, P.5
-
17
-
-
28644447707
-
Genome sequence, comparative analysis and haplotype structure of the domestic dog
-
DOI 10.1038/nature04338
-
Lindblad-Toh K, Wade CM, Mikkelsen TS, Karlsson EK, Jaffe DB, et al. (2005) Genome sequence, comparative analysis and haplotype structure of the domestic dog. Nature 438: 803-819. (Pubitemid 41753059)
-
(2005)
Nature
, vol.438
, Issue.7069
, pp. 803-819
-
-
Lindblad-Toh, K.1
Wade, C.M.2
Mikkelsen, T.S.3
Karlsson, E.K.4
Jaffe, D.B.5
Kamal, M.6
Clamp, M.7
Chang, J.L.8
Kulbokas III, E.J.9
Zody, M.C.10
Mauceli, E.11
Xie, X.12
Breen, M.13
Wayne, R.K.14
Ostrander, E.A.15
Ponting, C.P.16
Galibert, F.17
Smith, D.R.18
DeJong, P.J.19
Kirkness, E.20
Alvarez, P.21
Biagi, T.22
Brockman, W.23
Butler, J.24
Chin, C.-W.25
Cook, A.26
Cuff, J.27
Daly, M.J.28
DeCaprio, D.29
Gnerre, S.30
Grabherr, M.31
Kellis, M.32
Kleber, M.33
Bardeleben, C.34
Goodstadt, L.35
Heger, A.36
Hitte, C.37
Kim, L.38
Koepfli, K.-P.39
Parker, H.G.40
Pollinger, J.P.41
Searle, S.M.J.42
Sutter, N.B.43
Thomas, R.44
Webber, C.45
Lander, E.S.46
more..
-
18
-
-
84880506371
-
Veterinary co-operative oncology group -Common terminology criteria for adverse events (vcog-ctcae) following chemotherapy or biological antineoplastic therapy in dogs and cats v1.1
-
Vail D (2011) Veterinary Co-operative Oncology Group -Common Terminology Criteria for Adverse Events (VCOG-CTCAE) following chemotherapy or biological antineoplastic therapy in dogs and cats v1.1. Veterinary and Comparative Oncology 10: 1-30.
-
(2011)
Veterinary and Comparative Oncology
, vol.10
, pp. 1-30
-
-
Vail, D.1
-
19
-
-
84879846037
-
A pilot trial testing the feasibility of using molecular-guided therapy in patients with recurrent neuroblastoma
-
Saulnier Sholler GL, Ferguson W, Bergendahl G, Currier E, Lenox SR, et al. (2012) A Pilot Trial Testing the Feasibility of Using Molecular-Guided Therapy in Patients with Recurrent Neuroblastoma. Journal of Cancer Therapy 3: pp. 602-612.
-
(2012)
Journal of Cancer Therapy
, vol.3
, pp. 602-612
-
-
Saulnier Sholler, G.L.1
Ferguson, W.2
Bergendahl, G.3
Currier, E.4
Lenox, S.R.5
-
20
-
-
79957789582
-
A compendium of canine normal tissue gene expression
-
Briggs J, Paoloni M, Chen QR, Wen X, Khan J, et al. (2011) A compendium of canine normal tissue gene expression. PLoS One 6: e17107.
-
(2011)
PLoS One
, vol.6
-
-
Briggs, J.1
Paoloni, M.2
Chen, Q.R.3
Wen, X.4
Khan, J.5
-
21
-
-
63749090726
-
Launching a novel preclinical infrastructure: Comparative oncology trials consortium directed therapeutic targeting of tnfalpha to cancer vasculature
-
Paoloni MC, Tandle A, Mazcko C, Hanna E, Kachala S, et al. (2009) Launching a novel preclinical infrastructure: comparative oncology trials consortium directed therapeutic targeting of TNFalpha to cancer vasculature. PLoS One 4: e4972.
-
(2009)
PLoS One
, vol.4
-
-
Paoloni, M.C.1
Tandle, A.2
Mazcko, C.3
Hanna, E.4
Kachala, S.5
-
22
-
-
84879471843
-
A multi-site feasibility study for personalized medicine in canines with osteosarcoma
-
Monks NR, Cherba DM, Kamerling SG, Simpson H, Rusk AW, et al. (2013) A multi-site feasibility study for personalized medicine in canines with Osteosarcoma. Journal of translational medicine 11: 158.
-
(2013)
Journal of translational medicine
, vol.11
, pp. 158
-
-
Monks, N.R.1
Cherba, D.M.2
Kamerling, S.G.3
Simpson, H.4
Rusk, A.W.5
-
23
-
-
78149410161
-
Mouse models of cancers: Opportunities to address heterogeneity of human cancer and evaluate therapeutic strategies
-
Andrechek ER, Nevins JR (2010) Mouse models of cancers: opportunities to address heterogeneity of human cancer and evaluate therapeutic strategies. J Mol Med (Berl) 88: 1095-1100.
-
(2010)
J Mol Med (Berl)
, vol.88
, pp. 1095-1100
-
-
Andrechek, E.R.1
Nevins, J.R.2
-
24
-
-
77449128013
-
Canine tumor cross-species genomics uncovers targets linked to osteosarcoma progression
-
Paoloni M, Davis S, Lana S, Withrow S, Sangiorgi L, et al. (2009) Canine tumor cross-species genomics uncovers targets linked to osteosarcoma progression. BMC genomics 10: 625.
-
(2009)
BMC genomics
, vol.10
, pp. 625
-
-
Paoloni, M.1
Davis, S.2
Lana, S.3
Withrow, S.4
Sangiorgi, L.5
-
25
-
-
84882579172
-
Gene profiling of canine b-cell lymphoma reveals germinal center and postgerminal center subtypes with different survival times, modeling human dlbcl
-
Richards KL, Motsinger-Reif AA, Chen H-w, Fedoriw Y, Fan C, et al. (2013) Gene profiling of canine B-cell lymphoma reveals germinal center and postgerminal center subtypes with different survival times, modeling human DLBCL. Cancer Research.
-
(2013)
Cancer Research
-
-
Richards, K.L.1
Motsinger-Reif, A.A.2
Chen H-w3
Fedoriw, Y.4
Fan, C.5
-
26
-
-
84898952607
-
The importance of a satisfactory biopsy for the diagnosis of lung cancer in the era of personalized treatment
-
Ofiara LM, Navasakulpong A, Ezer N, Gonzalez AV (2012) The importance of a satisfactory biopsy for the diagnosis of lung cancer in the era of personalized treatment. Curr Oncol 19: S16-23.
-
(2012)
Curr Oncol
, vol.19
-
-
Ofiara, L.M.1
Navasakulpong, A.2
Ezer, N.3
Gonzalez, A.V.4
-
27
-
-
78649351681
-
Personalized medicine in oncology: A personal view with myths and facts
-
Beijnen JH, Schellens JH (2010) Personalized medicine in oncology: a personal view with myths and facts. Curr Clin Pharmacol 5: 141-147.
-
(2010)
Curr Clin Pharmacol
, vol.5
, pp. 141-147
-
-
Beijnen, J.H.1
Schellens, J.H.2
-
28
-
-
84855668129
-
How comparative effectiveness research can help advance'personalized medicine' in cancer treatment
-
Ramsey SD, Veenstra D, Tunis SR, Garrison L, Crowley JJ, et al. (2011) How comparative effectiveness research can help advance 'personalized medicine' in cancer treatment. Health Aff (Millwood) 30: 2259-2268.
-
(2011)
Health Aff (Millwood)
, vol.30
, pp. 2259-2268
-
-
Ramsey, S.D.1
Veenstra, D.2
Tunis, S.R.3
Garrison, L.4
Crowley, J.J.5
-
29
-
-
77956205777
-
Rapamycin pharmacokinetic and pharmacodynamic relationships in osteosarcoma: A comparative oncology study in dogs
-
Paoloni MC, Mazcko C, Fox E, Fan T, Lana S, et al. (2010) Rapamycin pharmacokinetic and pharmacodynamic relationships in osteosarcoma: a comparative oncology study in dogs. PLoS One 5: e11013.
-
(2010)
PLoS One
, vol.5
-
-
Paoloni, M.C.1
Mazcko, C.2
Fox, E.3
Fan, T.4
Lana, S.5
-
30
-
-
84898661475
-
-
NCI NCI-Bioinformatics Oracle -[current version 2007 Jan; cited 2008 June]) Cancer Central Clinical Database (C3D) [Internet]. Version 4.5.2
-
NCI, NCI-Bioinformatics, Oracle (2002 Fall -[current version 2007 Jan; cited 2008 June]) Cancer Central Clinical Database (C3D) [Internet]. Version 4.5.2.
-
(2002)
Fall
-
-
-
32
-
-
78651287426
-
Drugbank 3.0: A comprehensive resource for 'omics' research on drugs
-
Knox C, Law V, Jewison T, Liu P, Ly S, et al. (2011) DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res 39: D1035-1041.
-
(2011)
Nucleic Acids Res
, vol.39
-
-
Knox, C.1
Law, V.2
Jewison, T.3
Liu, P.4
Ly, S.5
-
33
-
-
33749335282
-
The connectivity map: Using gene-expression signatures to connect small molecules, genes, and disease
-
DOI 10.1126/science.1132939
-
Lamb J, Crawford ED, Peck D, Modell JW, Blat IC, et al. (2006) The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease. Science 313: 1929-1935. (Pubitemid 44497995)
-
(2006)
Science
, vol.313
, Issue.5795
, pp. 1929-1935
-
-
Lamb, J.1
Crawford, E.D.2
Peck, D.3
Modell, J.W.4
Blat, I.C.5
Wrobel, M.J.6
Lerner, J.7
Brunet, J.-P.8
Subramanian, A.9
Ross, K.N.10
Reich, M.11
Hieronymus, H.12
Wei, G.13
Armstrong, S.A.14
Haggarty, S.J.15
Clemons, P.A.16
Wei, R.17
Carr, S.A.18
Lander, E.S.19
Golub, T.R.20
more..
-
34
-
-
34248168006
-
Detection of DNA copy number changes and oncogenic signaling abnormalities from gene expression data reveals MYC activation in high-grade papillary renal cell carcinoma
-
DOI 10.1158/0008-5472.CAN-06-4571
-
Furge KA, Chen J, Koeman J, Swiatek P, Dykema K, et al. (2007) Detection of DNA copy number changes and oncogenic signaling abnormalities from gene expression data reveals MYC activation in high-grade papillary renal cell carcinoma. Cancer Res 67: 3171-3176. (Pubitemid 46724854)
-
(2007)
Cancer Research
, vol.67
, Issue.7
, pp. 3171-3176
-
-
Furge, K.A.1
Chen, J.2
Koeman, J.3
Swiatek, P.4
Dykema, K.5
Lucin, K.6
Kahnoski, R.7
Yang, X.J.8
Bin, T.T.9
-
35
-
-
34548799629
-
A strategy for predicting the chemosensitivity of human cancers and its application to drug discovery
-
DOI 10.1073/pnas.0610292104
-
Lee JK, Havaleshko DM, Cho H, Weinstein JN, Kaldjian EP, et al. (2007) A strategy for predicting the chemosensitivity of human cancers and its application to drug discovery. Proc Natl Acad Sci U S A 104: 13086-13091. (Pubitemid 351737597)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.32
, pp. 13086-13091
-
-
Lee, J.K.1
Havaleshko, D.M.2
Cho, H.3
Weinstein, J.N.4
Kaldjian, E.P.5
Karpovich, J.6
Grimshaw, A.7
Theodorescu, D.8
-
36
-
-
0035845531
-
Chemosensitivity prediction by transcriptional profiling
-
DOI 10.1073/pnas.191368598
-
Staunton JE, Slonim DK, Coller HA, Tamayo P, Angelo MJ, et al. (2001) Chemosensitivity prediction by transcriptional profiling. Proc Natl Acad SciUS A 98: 10787-10792. (Pubitemid 32878698)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.19
, pp. 10787-10792
-
-
Staunton, J.E.1
Slonim, D.K.2
Coller, H.A.3
Tamayo, P.4
Angelo, M.J.5
Park, J.6
Scherf, U.7
Lee, J.K.8
Reinhold, W.O.9
Weinstein, J.N.10
Mesirov, J.P.11
Lander, E.S.12
Golub, T.R.13
-
37
-
-
75749154422
-
Screening a panel of drugs with diverse mechanisms of action yields potential therapeutic agents against neuroblastoma
-
Gheeya JS, Chen QR, Benjamin CD, Cheuk AT, Tsang P, et al. (2009) Screening a panel of drugs with diverse mechanisms of action yields potential therapeutic agents against neuroblastoma. Cancer Biol Ther 8: 2386-2395.
-
(2009)
Cancer Biol Ther
, vol.8
, pp. 2386-2395
-
-
Gheeya, J.S.1
Chen, Q.R.2
Benjamin, C.D.3
Cheuk, A.T.4
Tsang, P.5
-
38
-
-
65549138481
-
Identifying disease-specific genes based on their topological significance in protein networks
-
Dezso Z, Nikolsky Y, Nikolskaya T, Miller J, Cherba D, et al. (2009) Identifying disease-specific genes based on their topological significance in protein networks. BMC Syst Biol 3: 36.
-
(2009)
BMC Syst Biol
, vol.3
, pp. 36
-
-
Dezso, Z.1
Nikolsky, Y.2
Nikolskaya, T.3
Miller, J.4
Cherba, D.5
|