-
1
-
-
79958766637
-
Molecular targeting of glioblastoma: Drug discovery and therapies
-
Bai RY, Staedtke V, Riggins GJ (2011) Molecular targeting of glioblastoma: Drug discovery and therapies. Trends Mol Med 17: 301-312.
-
(2011)
Trends Mol Med
, vol.17
, pp. 301-312
-
-
Bai, R.Y.1
Staedtke, V.2
Riggins, G.J.3
-
2
-
-
70350450778
-
Perspectives on the development of imatinib and the future of cancer research
-
Druker BJ (2009) Perspectives on the development of imatinib and the future of cancer research. Nat Med 15: 1149-1152.
-
(2009)
Nat Med
, vol.15
, pp. 1149-1152
-
-
Druker, B.J.1
-
3
-
-
34547638047
-
Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer
-
DOI 10.1038/nature05945, PII NATURE05945
-
Soda M, Choi YL, Enomoto M, Takada S, Yamashita Y, et al. (2007) Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer. Nature 448: 561-566. (Pubitemid 47206930)
-
(2007)
Nature
, vol.448
, Issue.7153
, pp. 561-566
-
-
Soda, M.1
Choi, Y.L.2
Enomoto, M.3
Takada, S.4
Yamashita, Y.5
Ishikawa, S.6
Fujiwara, S.-I.7
Watanabe, H.8
Kurashina, K.9
Hatanaka, H.10
Bando, M.11
Ohno, S.12
Ishikawa, Y.13
Aburatani, H.14
Niki, T.15
Sohara, Y.16
Sugiyama, Y.17
Mano, H.18
-
4
-
-
27344451557
-
Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer
-
DOI 10.1126/science.1117679
-
Tomlins SA, Rhodes DR, Perner S, Dhanasekaran SM, Mehra R, et al. (2005) Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. Science 310: 644-648. (Pubitemid 41528150)
-
(2005)
Science
, vol.310
, Issue.5748
, pp. 644-648
-
-
Tomlins, S.A.1
Rhodes, D.R.2
Perner, S.3
Dhanasekaran, S.M.4
Mehra, R.5
Sun, X.-W.6
Varambally, S.7
Cao, X.8
Tchinda, J.9
Kuefer, R.10
Lee, C.11
Montie, J.E.12
Shah, R.B.13
Pienta, K.J.14
Rubin, M.A.15
Chinnaiyan, A.M.16
-
5
-
-
84863230117
-
A transforming KIF5B and RET gene fusion in lung adenocarcinoma revealed from whole-genome and transcriptome sequencing
-
Ju YS, Lee WC, Shin JY, Lee S, Bleazard T, et al. (2012) A transforming KIF5B and RET gene fusion in lung adenocarcinoma revealed from whole-genome and transcriptome sequencing. Genome Res 22: 436-445.
-
(2012)
Genome Res
, vol.22
, pp. 436-445
-
-
Ju, Y.S.1
Lee, W.C.2
Shin, J.Y.3
Lee, S.4
Bleazard, T.5
-
6
-
-
84865805666
-
Transforming fusions of FGFR and TACC genes in human glioblastoma
-
Singh D, Chan JM, Zoppoli P, Niola F, Sullivan R, et al. (2012) Transforming fusions of FGFR and TACC genes in human glioblastoma. Science 337: 1231-1235.
-
(2012)
Science
, vol.337
, pp. 1231-1235
-
-
Singh, D.1
Chan, J.M.2
Zoppoli, P.3
Niola, F.4
Sullivan, R.5
-
7
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
The Cancer Genome Atlas Research Network
-
The Cancer Genome Atlas Research Network (2008) Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 455: 1061-1068.
-
(2008)
Nature
, vol.455
, pp. 1061-1068
-
-
-
8
-
-
77958040520
-
FusionSeq: A modular framework for finding gene fusions by analyzing paired-end RNA-sequencing data
-
Sboner A, Habegger L, Pflueger D, Terry S, Chen DZ, et al. (2010) FusionSeq: a modular framework for finding gene fusions by analyzing paired-end RNA-sequencing data. Genome Biol 11: R104.
-
(2010)
Genome Biol
, vol.11
-
-
Sboner, A.1
Habegger, L.2
Pflueger, D.3
Terry, S.4
Chen, D.Z.5
-
9
-
-
84865214708
-
Gene fusions associated with recurrent amplicons represent a class of passenger aberrations in breast cancer
-
Kalyana-Sundaram S, Shankar S, Deroo S, Iyer MK, Palanisamy N, et al. (2012) Gene fusions associated with recurrent amplicons represent a class of passenger aberrations in breast cancer. Neoplasia 14: 702-708.
-
(2012)
Neoplasia
, vol.14
, pp. 702-708
-
-
Kalyana-Sundaram, S.1
Shankar, S.2
Deroo, S.3
Iyer, M.K.4
Palanisamy, N.5
-
10
-
-
84885074034
-
The somatic genomic landscape of glioblastoma
-
Brennan CW, Verhaak RG, McKenna A, Campos B, Noushmehr H, et al. (2013) The somatic genomic landscape of glioblastoma. Cell 155: 462-477.
-
(2013)
Cell
, vol.155
, pp. 462-477
-
-
Brennan, C.W.1
Verhaak, R.G.2
McKenna, A.3
Campos, B.4
Noushmehr, H.5
-
11
-
-
84884996623
-
The integrated landscape of driver genomic alterations in glioblastoma
-
Frattini V, Trifonov V, Chan JM, Castano A, Lia M, et al. (2013) The integrated landscape of driver genomic alterations in glioblastoma. Nat Genet 45: 1141-1149.
-
(2013)
Nat Genet
, vol.45
, pp. 1141-1149
-
-
Frattini, V.1
Trifonov, V.2
Chan, J.M.3
Castano, A.4
Lia, M.5
-
12
-
-
84887926034
-
Exploration of the gene fusion landscape of glioblastoma using transcriptome sequencing and copy number data
-
Shah N, Lankerovich M, Lee H, Yoon JG, Schroeder B, et al. (2013) Exploration of the gene fusion landscape of glioblastoma using transcriptome sequencing and copy number data. BMC Genomics 14: 818.
-
(2013)
BMC Genomics
, vol.14
, pp. 818
-
-
Shah, N.1
Lankerovich, M.2
Lee, H.3
Yoon, J.G.4
Schroeder, B.5
-
13
-
-
0025875819
-
Dissection of the protein kinase cascade by which nerve growth factor activates MAP kinases
-
Gomez N, Cohen P (1991) Dissection of the protein kinase cascade by which nerve growth factor activates MAP kinases. Nature 353: 170-173. (Pubitemid 21912483)
-
(1991)
Nature
, vol.353
, Issue.6340
, pp. 170-173
-
-
Gomez, N.1
Cohen, P.2
-
14
-
-
5444258188
-
TrkA alternative splicing: A regulated tumor-promoting switch in human neuroblastoma
-
DOI 10.1016/j.ccr.2004.09.011, PII S1535610804002715
-
Tacconelli A, Farina AR, Cappabianca L, Desantis G, Tessitore A, et al. (2004) TrkA alternative splicing: a regulated tumor-promoting switch in human neuroblastoma. Cancer Cell 6: 347-360. (Pubitemid 39361436)
-
(2004)
Cancer Cell
, vol.6
, Issue.4
, pp. 347-360
-
-
Tacconelli, A.1
Farina, A.R.2
Cappabianca, L.3
DeSantis, G.4
Tessitore, A.5
Vetuschi, A.6
Sferra, R.7
Rucci, N.8
Argenti, B.9
Screpanti, I.10
Gulino, A.11
Mackay, A.R.12
-
15
-
-
34250378582
-
Tyrosine kinase inhibitor CEP-701 blocks the NTRK1/NGF receptor and limits the invasive capability of prostate cancer cells in vitro
-
Festuccia C, Muzi P, Gravina GL, Millimaggi D, Speca S, et al. (2007) Tyrosine kinase inhibitor CEP-701 blocks the NTRK1/NGF receptor and limits the invasive capability of prostate cancer cells in vitro. Int J Oncol 30: 193-200.
-
(2007)
Int J Oncol
, vol.30
, pp. 193-200
-
-
Festuccia, C.1
Muzi, P.2
Gravina, G.L.3
Millimaggi, D.4
Speca, S.5
-
16
-
-
0022641294
-
A human oncogene formed by the fusion of truncated tropomyosin and protein tyrosine kinase sequences
-
Martin-Zanca D, Hughes SH, Barbacid M (1986) A human oncogene formed by the fusion of truncated tropomyosin and protein tyrosine kinase sequences. Nature 319: 743-748. (Pubitemid 16145029)
-
(1986)
Nature
, vol.319
, Issue.6056
, pp. 743-748
-
-
Martin-Zanca, D.1
Hughes, S.H.2
Barbacid, M.3
-
17
-
-
77950939830
-
Rearrangements of NTRK1 gene in papillary thyroid carcinoma
-
Greco A, Miranda C, Pierotti MA (2010) Rearrangements of NTRK1 gene in papillary thyroid carcinoma. Mol Cell Endocrinol 321: 44-49.
-
(2010)
Mol Cell Endocrinol
, vol.321
, pp. 44-49
-
-
Greco, A.1
Miranda, C.2
Pierotti, M.A.3
-
18
-
-
84887445619
-
Oncogenic and drug-sensitive NTRK1 rearrangements in lung cancer
-
Vaishnavi A, Capelletti M, Le AT, Kako S, Butaney M, et al. (2013) Oncogenic and drug-sensitive NTRK1 rearrangements in lung cancer. Nat Med 19: 1469-1472.
-
(2013)
Nat Med
, vol.19
, pp. 1469-1472
-
-
Vaishnavi, A.1
Capelletti, M.2
Le, A.T.3
Kako, S.4
Butaney, M.5
-
19
-
-
5444260773
-
Ankyrin-based subcellular gradient of neurofascin, an immunoglobulin family protein, directs GABAergic innervation at Purkinje axon initial segment
-
DOI 10.1016/j.cell.2004.10.004, PII S009286740400947X
-
Ango F, di Cristo G, Higashiyama H, Bennett V, Wu P, et al. (2004) Ankyrin-based subcellular gradient of neurofascin, an immunoglobulin family protein, directs GABAergic innervation at purkinje axon initial segment. Cell 119: 257-272. (Pubitemid 39360907)
-
(2004)
Cell
, vol.119
, Issue.2
, pp. 257-272
-
-
Ango, F.1
Di, C.G.2
Higashiyama, H.3
Bennett, V.4
Wu, P.5
Huang, Z.J.6
-
20
-
-
0028233391
-
Molecular cloning of brevican, a novel brain proteoglycan of the aggrecan/versican family
-
Yamada H, Watanabe K, Shimonaka M, Yamaguchi Y (1994) Molecular cloning of brevican, a novel brain proteoglycan of the aggrecan/versican family. J Biol Chem 269: 10119-10126. (Pubitemid 24196631)
-
(1994)
Journal of Biological Chemistry
, vol.269
, Issue.13
, pp. 10119-10126
-
-
Yamada, H.1
Watanabe, K.2
Shimonaka, M.3
Yamaguchi, Y.4
-
21
-
-
11144358198
-
A gene atlas of the mouse and human protein-encoding transcriptomes
-
DOI 10.1073/pnas.0400782101
-
Su AI, Wiltshire T, Batalov S, Lapp H, Ching KA, et al. (2004) A gene atlas of the mouse and human protein-encoding transcriptomes. Proc Natl Acad Sci U S A 101: 6062-6067. (Pubitemid 38520528)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.16
, pp. 6062-6067
-
-
Su, A.I.1
Wiltshire, T.2
Batalov, S.3
Lapp, H.4
Ching, K.A.5
Block, D.6
Zhang, J.7
Soden, R.8
Hayakawa, M.9
Kreiman, G.10
Cooke, M.P.11
Walker, J.R.12
Hogenesch, J.B.13
-
22
-
-
0031038873
-
Promoter swapping between the genes for a novel zinc finger protein and beta-catenin in pleiomorphic adenomas with t(3;8)(p21;q12) translocations
-
DOI 10.1038/ng0297-170
-
Kas K, Voz ML, Roijer E, Astrom AK, Meyen E, et al. (1997) Promoter swapping between the genes for a novel zinc finger protein and beta-catenin in pleiomorphic adenomas with t(3;8)(p21;q12) translocations. Nat Genet 15: 170-174. (Pubitemid 27061636)
-
(1997)
Nature Genetics
, vol.15
, Issue.2
, pp. 170-174
-
-
Kas, K.1
Voz, M.L.2
Roijer, E.3
Astrom, A.-K.4
Meyen, E.5
Stenman, G.6
Van De, V.W.J.M.7
-
23
-
-
67651148122
-
Identification and preclinical characterization of AZ-23, a novel, selective, and orally bioavailable inhibitor of the Trk kinase pathway
-
Thress K, Macintyre T, Wang H, Whitston D, Liu ZY, et al. (2009) Identification and preclinical characterization of AZ-23, a novel, selective, and orally bioavailable inhibitor of the Trk kinase pathway. Mol Cancer Ther 8: 1818-1827.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 1818-1827
-
-
Thress, K.1
Macintyre, T.2
Wang, H.3
Whitston, D.4
Liu, Z.Y.5
-
24
-
-
78649445485
-
Caveolin-1 inhibits TrkA-induced cell death by influencing on TrkA modification associated with tyrosine-490 phosphorylation
-
Jung EJ, Kim CW (2010) Caveolin-1 inhibits TrkA-induced cell death by influencing on TrkA modification associated with tyrosine-490 phosphorylation. Biochem Biophys Res Commun 402: 736-741.
-
(2010)
Biochem Biophys Res Commun
, vol.402
, pp. 736-741
-
-
Jung, E.J.1
Kim, C.W.2
-
25
-
-
78049425319
-
Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer
-
Kwak EL, Bang YJ, Camidge DR, Shaw AT, Solomon B, et al. (2010) Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer. N Engl J Med 363: 1693-1703.
-
(2010)
N Engl J Med
, vol.363
, pp. 1693-1703
-
-
Kwak, E.L.1
Bang, Y.J.2
Camidge, D.R.3
Shaw, A.T.4
Solomon, B.5
-
26
-
-
84864286442
-
Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors
-
Wilson TR, Fridlyand J, Yan Y, Penuel E, Burton L, et al. (2012) Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature 487: 505-509.
-
(2012)
Nature
, vol.487
, pp. 505-509
-
-
Wilson, T.R.1
Fridlyand, J.2
Yan, Y.3
Penuel, E.4
Burton, L.5
-
27
-
-
84873110988
-
Patient-specific orthotopic glioblastoma xenograft models recapitulate the histopathology and biology of human glioblastomas in situ
-
Joo KM, Kim J, Jin J, Kim M, Seol HJ, et al. (2013) Patient-specific orthotopic glioblastoma xenograft models recapitulate the histopathology and biology of human glioblastomas in situ. Cell Rep 3: 260-273.
-
(2013)
Cell Rep
, vol.3
, pp. 260-273
-
-
Joo, K.M.1
Kim, J.2
Jin, J.3
Kim, M.4
Seol, H.J.5
-
28
-
-
0033860103
-
TrkA Immunoglobulin-like ligand binding domains inhibit spontaneous activation of the receptor
-
DOI 10.1128/MCB.20.16.5908-5916.2000
-
Arevalo JC, Conde B, Hempstead BL, Chao MV, Martin-Zanca D, et al. (2000) TrkA immunoglobulin-like ligand binding domains inhibit spontaneous activation of the receptor. Mol Cell Biol 20: 5908-5916. (Pubitemid 30613040)
-
(2000)
Molecular and Cellular Biology
, vol.20
, Issue.16
, pp. 5908-5916
-
-
Arevalo, J.C.1
Conde, B.2
Hempstead, B.L.3
Chao, M.V.4
Martin-Zanca, D.5
Perez, P.6
-
29
-
-
77951820899
-
Fast and SNP-tolerant detection of complex variants and splicing in short reads
-
Wu TD, Nacu S (2010) Fast and SNP-tolerant detection of complex variants and splicing in short reads. Bioinformatics 26: 873-881.
-
(2010)
Bioinformatics
, vol.26
, pp. 873-881
-
-
Wu, T.D.1
Nacu, S.2
-
30
-
-
78649508797
-
Nearest template prediction: A single-sample-based flexible class prediction with confidence assessment
-
Hoshida Y (2010) Nearest template prediction: a single-sample-based flexible class prediction with confidence assessment. PLoS ONE 5: e15543.
-
(2010)
PLoS ONE
, vol.5
-
-
Hoshida, Y.1
|