Shared and unique signals of high-altitude adaptation in geographically distinct tibetan populations

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Wuren, Tana ^a   Simonson, Tatum S ^b,c   Qin, Ga ^a   Xing, Jinchuan ^c   Huff, Chad D ^c   Witherspoon, David J ^c   Jorde, Lynn B ^c   Ge, Ri Li ^a  

^a QINGHAI UNIVERSITY   (China)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; EGLN1 PROTEIN, HUMAN; ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1; HEME OXYGENASE; HEME OXYGENASE-2; HYPOXIA INDUCIBLE FACTOR PROLINE DIOXYGENASE; MITOCHONDRIAL DNA;

ALTITUDE ACCLIMATIZATION; ARTICLE; CHINA; CONTROLLED STUDY; CYP17A1 GENE; DNA DETERMINATION; EGLN1 GENE; EPAS1 GENE; ETHNIC GROUP; GENE; GENE FREQUENCY; GENE LOCUS; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOME ANALYSIS; GENOTYPE PHENOTYPE CORRELATION; GEOGRAPHICAL VARIATION (SPECIES); HAPLOTYPE; HBB GENE; HBG2 GENE; HEMOGLOBIN DETERMINATION; HFE GENE; HMOX2 GENE; HUMAN; MOLECULAR PHYLOGENY; NATURAL SELECTION; PKLR GENE; POPULATION DIFFERENTIATION; RACE DIFFERENCE; SIGNAL DETECTION; SINGLE NUCLEOTIDE POLYMORPHISM; ADAPTATION; ADOLESCENT; ADULT; AGED; ALLELE; ALTITUDE; ANOXIA; ASIAN CONTINENTAL ANCESTRY GROUP; ETHNOLOGY; FEMALE; GENETIC SELECTION; GENETICS; MALE; MIDDLE AGED;

ADAPTATION, PHYSIOLOGICAL; ADOLESCENT; ADULT; AGED; ALLELES; ALTITUDE; ANOXIA; ASIAN CONTINENTAL ANCESTRY GROUP; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; DNA, MITOCHONDRIAL; FEMALE; GENOME-WIDE ASSOCIATION STUDY; HAPLOTYPES; HEME OXYGENASE (DECYCLIZING); HUMANS; HYPOXIA-INDUCIBLE FACTOR-PROLINE DIOXYGENASES; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; SELECTION, GENETIC; TIBET;

EID: 84898652859     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0088252     Document Type: Article

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