Mitochondrial DNA variant associated with Leber hereditary optic neuropathy and high-altitude Tibetans

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 19, 2012, Pages 7391-7396

  Ji, Fuyun ^a   Sharpley, Mark S ^b,c   Derbeneva, Olga ^b,c   Alves, Leonardo Scherer ^b,c   Qian, Pin ^a   Wang, Yaoli ^a   Chalkia, Dimitra ^b,c   Lvova, Maria ^b,c   Xu, Jiancheng ^a   Yao, Wei ^a   Simon, Mariella ^c   Platt, Julia ^c   Xu, Shiqin ^c   Angelin, Alessia ^b,c   Davila, Antonio ^b,c   Huang, Taosheng ^c   Wang, Ping H ^d   Chuang, Lee Ming ^e   Moore, Lorna G ^f   Qian, Guisheng ^a   Wallace, Douglas C ^b,c   more..

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^f WAKE FOREST UNIVERSITY   (United States)

Author keywords

Adaptation; Complex disease; Hypoxia; OXPHOS

Indexed keywords

MITOCHONDRIAL DNA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE);

ALTITUDE; ARTICLE; CHINA; CONTROLLED STUDY; ENVIRONMENTAL FACTOR; ENZYME ACTIVITY; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; GENETIC VARIABILITY; HAPLOTYPE; HUMAN; LEBER HEREDITARY OPTIC NEUROPATHY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

ALLELES; ALTITUDE; AMINO ACID SUBSTITUTION; ASIAN CONTINENTAL ANCESTRY GROUP; CELL LINE, TUMOR; DNA, MITOCHONDRIAL; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HUMANS; MOLECULAR SEQUENCE DATA; NADH DEHYDROGENASE; OPTIC ATROPHY, HEREDITARY, LEBER; OXYGEN CONSUMPTION; POLYMORPHISM, GENETIC; SEQUENCE ANALYSIS, DNA; TIBET;

EID: 84860806864     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1202484109     Document Type: Article

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