Epigenetic repression of phosphatidylethanolamine N-methyltransferase (PEMT) in BRCA1-mutated breast cancer

Oncotarget

Volumn 5, Issue 5, 2014, Pages 1315-1325

  Li, Da ^a   Bi, Fang Fang ^a   Chen, Na Na ^b   Cao, Ji Min ^c   Sun, Wu Ping ^d   Zhou, Yi Ming ^d   Cao, Chen ^e   Li, Chun Yan ^c   Yang, Qing ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

^b NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

^d NATIONAL INSTITUTE FOR PHYSIOLOGICAL SCIENCES   (Japan)

^e CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

BRCA1; Breast cancer; DNA methylation; Histone modifications; PEMT

Indexed keywords

BRCA1 PROTEIN; ESTROGEN RECEPTOR; HISTONE H3; MESSENGER RNA; PHOSPHATIDYLETHANOLAMINE METHYLTRANSFERASE; EHMT1 PROTEIN, HUMAN; HISTONE; HISTONE ACETYLTRANSFERASE PCAF; HISTONE LYSINE METHYLTRANSFERASE; HOLOCARBOXYLASE SYNTHETASES; LIGASE; P300-CBP-ASSOCIATED FACTOR; PEMT PROTEIN, HUMAN;

ADULT; ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CANCER GRADING; CANCER GROWTH; CANCER PATIENT; CANCER PROGNOSIS; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA METHYLATION; EPIGENETICS; FEMALE; GENE MUTATION; GENE REPRESSION; HISTONE METHYLATION; HISTOPATHOLOGY; HUMAN; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; PEMT GENE; PROMOTER REGION; PROTEIN DEPLETION; TRANSCRIPTION TERMINATION; BREAST TUMOR; EPIGENETIC REPRESSION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; KAPLAN MEIER METHOD; METABOLISM; MIDDLE AGED; MUTATION; PAGET NIPPLE DISEASE; PATHOLOGY; PROPORTIONAL HAZARDS MODEL; SECONDARY; TUMOR CELL CULTURE; TUMOR SUPPRESSOR GENE;

BREAST NEOPLASMS; CARBON-NITROGEN LIGASES; CARCINOMA, DUCTAL, BREAST; DNA METHYLATION; EPIGENETIC REPRESSION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, BRCA1; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; HUMANS; KAPLAN-MEIER ESTIMATE; MIDDLE AGED; MUTATION; P300-CBP TRANSCRIPTION FACTORS; PHOSPHATIDYLETHANOLAMINE N-METHYLTRANSFERASE; PROMOTER REGIONS, GENETIC; PROPORTIONAL HAZARDS MODELS; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED;

EID: 84898621816     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.1800     Document Type: Article

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