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Volumn 9, Issue 3, 2014, Pages

Whole blood transcriptomics and urinary metabolomics to define adaptive biochemical pathways of high- intensity exercise in 50-60 year old masters athletes

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTATION; ADULT; AEROBIC CAPACITY; AGE DISTRIBUTION; AGING; ARTICLE; ATHLETE; BLOOD ANALYSIS; BLOOD SAMPLING; CARDIOVASCULAR FUNCTION; CONTROLLED STUDY; CYCLING; CYP26B1 GENE; DNA MICROARRAY; DOCK4 GENE; ENDURANCE TRAINING; EXERCISE INTENSITY; GENE; GENE EXPRESSION; GENE IDENTIFICATION; GENETIC ASSOCIATION; GENETIC MARKER; HSD11B1 GENE; HUMAN; HUMAN EXPERIMENT; IGF1R GENE; IGF2 GENE; INSIG2 GENE; INSULIN SENSITIVITY; LEPR GENE; LIPID ANALYSIS; LOAD CARRYING CAPACITY; LPIN1 GENE; MALE; METABOLOMICS; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OCLN GENE; OLFM4 GENE; SLC5A11 GENE; TPO GENE; TRANSCRIPTOMICS; TRPC1 GENE; UQCRB GENE; URINALYSIS; UTS2 GENE; VETERAN; VIPR2 GENE; AGED; CASE CONTROL STUDY; ENDURANCE; ENERGY METABOLISM; EXERCISE; GENE EXPRESSION REGULATION; GENETICS; METABOLOME; MIDDLE AGED; OXYGEN CONSUMPTION; SIGNAL TRANSDUCTION;

EID: 84898621392     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0092031     Document Type: Article
Times cited : (45)

References (68)
  • 1
    • 70450215504 scopus 로고    scopus 로고
    • Effects of physical activity on cardiovascular and noncardiovascular outcomes in older adults
    • viii-ix
    • Sattelmair JR, Pertman JH, Forman DE (2009) Effects of physical activity on cardiovascular and noncardiovascular outcomes in older adults. Clin Geriatr Med 25: 677-702, viii-ix.
    • (2009) Clin Geriatr Med , vol.25 , pp. 677-702
    • Sattelmair, J.R.1    Pertman, J.H.2    Forman, D.E.3
  • 3
    • 33846138685 scopus 로고    scopus 로고
    • Exercise affects the gene expression profiles of human white blood cells
    • DOI 10.1152/japplphysiol.00066.2006
    • Buttner P, Mosig S, Lechtermann A, Funke H, Mooren FC (2007) Exercise affects the gene expression profiles of human white blood cells. J Appl Physiol 102: 26-36. (Pubitemid 46089748)
    • (2007) Journal of Applied Physiology , vol.102 , Issue.1 , pp. 26-36
    • Buttner, P.1    Mosig, S.2    Lechtermann, A.3    Funke, H.4    Mooren, F.C.5
  • 5
    • 72949106005 scopus 로고    scopus 로고
    • Effect of exercise on gene expression profile in unfractionated peripheral blood leukocytes
    • Nakamura S, Kobayashi M, Sugino T, Kajimoto O, Matoba R, et al. (2010) Effect of exercise on gene expression profile in unfractionated peripheral blood leukocytes. Biochem Biophys Res Commun 391: 846-851.
    • (2010) Biochem Biophys Res Commun , vol.391 , pp. 846-851
    • Nakamura, S.1    Kobayashi, M.2    Sugino, T.3    Kajimoto, O.4    Matoba, R.5
  • 7
    • 33646369182 scopus 로고    scopus 로고
    • CDNAmicroarray analysis as a research tool for expression profiling in human peripheral blood following exercise
    • Zieker D, Zieker J, Dietzsch J, Burnet M, Northoff H, et al. (2005) CDNAmicroarray analysis as a research tool for expression profiling in human peripheral blood following exercise. Exerc Immunol Rev 11: 86-96.
    • (2005) Exerc Immunol Rev , vol.11 , pp. 86-96
    • Zieker, D.1    Zieker, J.2    Dietzsch, J.3    Burnet, M.4    Northoff, H.5
  • 8
    • 0141780839 scopus 로고    scopus 로고
    • Serial analysis of gene expression in the skeletal muscle of endurance athletes compared to sedentary men
    • DOI 10.1096/fj.02-1200com
    • Yoshioka M, Tanaka H, Shono N, Snyder EE, Shindo M, et al. (2003) Serial analysis of gene expression in the skeletal muscle of endurance athletes compared to sedentary men. FASEB J 17: 1812-1819. (Pubitemid 37214775)
    • (2003) FASEB Journal , vol.17 , Issue.13 , pp. 1812-1819
    • Yoshioka, M.1    Tanaka, H.2    Shono, N.3    Snyder, E.E.4    Shindo, M.5    St-Amand, J.6
  • 9
    • 66149125319 scopus 로고    scopus 로고
    • Global gene expression in skeletal muscle from well-trained strength and endurance athletes
    • Stepto NK, Coffey VG, Carey AL, Ponnampalam AP, Canny BJ, et al. (2009) Global gene expression in skeletal muscle from well-trained strength and endurance athletes. Med Sci Sports Exerc 41: 546-565.
    • (2009) Med Sci Sports Exerc , vol.41 , pp. 546-565
    • Stepto, N.K.1    Coffey, V.G.2    Carey, A.L.3    Ponnampalam, A.P.4    Canny, B.J.5
  • 10
    • 33344454373 scopus 로고    scopus 로고
    • The peripheral blood transcriptome dynamically reflects system wide biology: A potential diagnostic tool
    • DOI 10.1016/j.lab.2005.10.005, PII S0022214305003835
    • Liew CC, Ma J, Tang HC, Zheng R, Dempsey AA (2006) The peripheral blood transcriptome dynamically reflects system wide biology: a potential diagnostic tool. J Lab Clin Med 147: 126-132. (Pubitemid 43288168)
    • (2006) Journal of Laboratory and Clinical Medicine , vol.147 , Issue.3 , pp. 126-132
    • Liew, C.-C.1    Ma, J.2    Tang, H.-C.3    Zheng, R.4    Dempsey, A.A.5
  • 12
    • 62149102697 scopus 로고    scopus 로고
    • Metabolomic investigation into variation of endogenous metabolites in professional athletes subject to strength-endurance training
    • Yan B, A J, Wang G, Lu H, Huang X, et al. (2009) Metabolomic investigation into variation of endogenous metabolites in professional athletes subject to strength-endurance training. J Appl Physiol 106: 531-538.
    • (2009) J Appl Physiol , vol.106 , pp. 531-538
    • Yan, B.1    Wang, G.2    Lu, H.3    Huang, X.4
  • 13
    • 76749107904 scopus 로고    scopus 로고
    • (1)H NMR-based metabolomics approach for exploring urinary metabolome modifications after acute and chronic physical exercise
    • Enea C, Seguin F, Petitpas-Mulliez J, Boildieu N, Boisseau N, et al. (2010) (1)H NMR-based metabolomics approach for exploring urinary metabolome modifications after acute and chronic physical exercise. Anal Bioanal Chem 396: 1167-1176.
    • (2010) Anal Bioanal Chem , vol.396 , pp. 1167-1176
    • Enea, C.1    Seguin, F.2    Petitpas-Mulliez, J.3    Boildieu, N.4    Boisseau, N.5
  • 14
    • 78649811837 scopus 로고    scopus 로고
    • H NMR-based metabonomic investigation of the effect of two different exercise sessions on the metabolic fingerprint of human urine
    • Pechlivanis A, Kostidis S, Saraslanidis P, Petridou A, Tsalis G, et al. (2010) (1)H NMR-based metabonomic investigation of the effect of two different exercise sessions on the metabolic fingerprint of human urine. J Proteome Res 9: 6405-6416.
    • (2010) J Proteome Res , vol.9 , pp. 6405-6416
    • Pechlivanis, A.1    Kostidis, S.2    Saraslanidis, P.3    Petridou, A.4    Tsalis, G.5
  • 15
    • 0041735423 scopus 로고    scopus 로고
    • Effects of the menstrual cycle on exercise performance
    • DOI 10.2165/00007256-200333110-00004
    • Janse de Jonge XA (2003) Effects of the menstrual cycle on exercise performance. Sports Med 33: 833-851. (Pubitemid 37108489)
    • (2003) Sports Medicine , vol.33 , Issue.11 , pp. 833-851
    • Janse De Jonge, X.A.K.1
  • 16
    • 33645663178 scopus 로고    scopus 로고
    • Scaling and normalization effects in NMR spectroscopic metabonomic data sets
    • Craig A, Cloarec O, Holmes E, Nicholson JK, Lindon JC (2006) Scaling and normalization effects in NMR spectroscopic metabonomic data sets. Anal Chem 78: 2262-2267.
    • (2006) Anal Chem , vol.78 , pp. 2262-2267
    • Craig, A.1    Cloarec, O.2    Holmes, E.3    Nicholson, J.K.4    Lindon, J.C.5
  • 19
    • 64949135371 scopus 로고    scopus 로고
    • Toward a systems biology framework for understanding aging and health span
    • West GB, Bergman A (2009) Toward a systems biology framework for understanding aging and health span. J Gerontol A Biol Sci Med Sci 64: 205-208.
    • (2009) J Gerontol A Biol Sci Med Sci , vol.64 , pp. 205-208
    • West, G.B.1    Bergman, A.2
  • 22
    • 36749082485 scopus 로고    scopus 로고
    • Using systems biology to define the essential biological networks responsible for adaptation to endurance exercise training
    • DOI 10.1042/BST0351306
    • Keller P, Vollaard N, Babraj J, Ball D, Sewell DA, et al. (2007) Using systems biology to define the essential biological networks responsible for adaptation to endurance exercise training. Biochem Soc Trans 35: 1306-1309. (Pubitemid 350206486)
    • (2007) Biochemical Society Transactions , vol.35 , Issue.5 , pp. 1306-1309
    • Keller, P.1    Vollaard, N.2    Babraj, J.3    Ball, D.4    Sewell, D.A.5    Timmons, J.A.6
  • 23
    • 77953164300 scopus 로고    scopus 로고
    • Using molecular classification to predict gains in maximal aerobic capacity following endurance exercise training in humans
    • Timmons JA, Knudsen S, Rankinen T, Koch LG, Sarzynski M, et al. (2010) Using molecular classification to predict gains in maximal aerobic capacity following endurance exercise training in humans. J Appl Physiol 108: 1487-1496.
    • (2010) J Appl Physiol , vol.108 , pp. 1487-1496
    • Timmons, J.A.1    Knudsen, S.2    Rankinen, T.3    Koch, L.G.4    Sarzynski, M.5
  • 24
    • 29444444389 scopus 로고    scopus 로고
    • Do blood cells mimic gene expression profile alterations known to occur in muscular adaptation to endurance training?
    • DOI 10.1007/s00421-005-1334-3
    • Zeibig J, Karlic H, Lohninger A, Damsgaard R, Smekal G (2005) Do blood cells mimic gene expression profile alterations known to occur in muscular adaptation to endurance training? Eur J Appl Physiol 95: 96-104. (Pubitemid 43008902)
    • (2005) European Journal of Applied Physiology , vol.95 , Issue.1 , pp. 96-104
    • Zeibig, J.1    Karlic, H.2    Lohninger, A.3    Dumsgaard, R.4    Smekal, G.5
  • 26
    • 0031888712 scopus 로고    scopus 로고
    • Skeletal muscle blood flow in humans and its regulation during exercise
    • DOI 10.1046/j.1365-201X.1998.0293e.x
    • Saltin B, Radegran G, Koskolou MD, Roach RC (1998) Skeletal muscle blood flow in humans and its regulation during exercise. Acta Physiol Scand 162: 421-436. (Pubitemid 28121421)
    • (1998) Acta Physiologica Scandinavica , vol.162 , Issue.3 , pp. 421-436
    • Saltin, B.1    Radegran, G.2    Koskolou, M.D.3    Roach, R.C.4
  • 27
    • 33646186499 scopus 로고    scopus 로고
    • Exercise, cognition and Alzheimer's disease: More is not necessarily better
    • Eggermont L, Swaab D, Luiten P, Scherder E (2006) Exercise, cognition and Alzheimer's disease: more is not necessarily better. Neurosci Biobehav Rev 30: 562-575.
    • (2006) Neurosci Biobehav Rev , vol.30 , pp. 562-575
    • Eggermont, L.1    Swaab, D.2    Luiten, P.3    Scherder, E.4
  • 28
    • 67949114536 scopus 로고    scopus 로고
    • Physical exercise leads to rapid adaptations in hippocampal vasculature: Temporal dynamics and relationship to cell proliferation and neurogenesis
    • Van der Borght K, Kobor-Nyakas DE, Klauke K, Eggen BJ, Nyakas C, et al. (2009) Physical exercise leads to rapid adaptations in hippocampal vasculature: temporal dynamics and relationship to cell proliferation and neurogenesis. Hippocampus 19: 928-936.
    • (2009) Hippocampus , vol.19 , pp. 928-936
    • Van Der Borght, K.1    Kobor-Nyakas, D.E.2    Klauke, K.3    Eggen, B.J.4    Nyakas, C.5
  • 30
    • 43049088925 scopus 로고    scopus 로고
    • Effects of physical exercise on skeletal muscle fiber: Ultrastructural and molecular aspects
    • Magaudda L, Di Mauro D, Trimarchi F, Anastasi G (2004) Effects of physical exercise on skeletal muscle fiber: ultrastructural and molecular aspects. Basic Appl Myol 14: 17-21.
    • (2004) Basic Appl Myol , vol.14 , pp. 17-21
    • Magaudda, L.1    Di Mauro, D.2    Trimarchi, F.3    Anastasi, G.4
  • 31
    • 77953721195 scopus 로고    scopus 로고
    • Characterization of the equine skeletal muscle transcriptome identifies novel functional responses to exercise training
    • McGivney BA, McGettigan PA, Browne JA, Evans AC, Fonseca RG, et al. (2010) Characterization of the equine skeletal muscle transcriptome identifies novel functional responses to exercise training. BMC Genomics 11: 398.
    • (2010) BMC Genomics , vol.11 , pp. 398
    • McGivney, B.A.1    McGettigan, P.A.2    Browne, J.A.3    Evans, A.C.4    Fonseca, R.G.5
  • 34
    • 13744252785 scopus 로고    scopus 로고
    • Reversing age-associated immunosenescence via exercise
    • Kohut ML, Senchina DS (2004) Reversing age-associated immunosenescence via exercise. Exerc Immunol Rev 10: 6-41.
    • (2004) Exerc Immunol Rev , vol.10 , pp. 6-41
    • Kohut, M.L.1    Senchina, D.S.2
  • 36
    • 0036401974 scopus 로고    scopus 로고
    • D-chiro-inositol-its functional role in insulin action and its deficit in insulin resistance
    • DOI 10.1080/15604280212528
    • Larner J (2002) D-chiro-inositol-its functional role in insulin action and its deficit in insulin resistance. Int J Exp Diabetes Res 3: 47-60. (Pubitemid 35174544)
    • (2002) International Journal of Experimental Diabetes Research , vol.3 , Issue.1 , pp. 47-60
    • Larner, J.1
  • 37
    • 83055168484 scopus 로고    scopus 로고
    • A quantitative proteomic approach of the different stages of colorectal cancer establishes OLFM4 as a new nonmetastatic tumor marker
    • Besson D, Pavageau A-H, Valo I, Bourreau A, Bélanger A, et al. (2011) A quantitative proteomic approach of the different stages of colorectal cancer establishes OLFM4 as a new nonmetastatic tumor marker. Molecular & Cellular Proteomics 10.
    • (2011) Molecular & Cellular Proteomics , vol.10
    • Besson, D.1    Pavageau, A.-H.2    Valo, I.3    Bourreau, A.4    Bélanger, A.5
  • 38
    • 70349880528 scopus 로고    scopus 로고
    • Serum olfactomedin 4 (GW112, hGC-1) in combination with Reg IV is a highly sensitive biomarker for gastric cancer patients
    • Oue N, Sentani K, Noguchi T, Ohara S, Sakamoto N, et al. (2009) Serum olfactomedin 4 (GW112, hGC-1) in combination with Reg IV is a highly sensitive biomarker for gastric cancer patients. Int J Cancer 125: 2383-2392.
    • (2009) Int J Cancer , vol.125 , pp. 2383-2392
    • Oue, N.1    Sentani, K.2    Noguchi, T.3    Ohara, S.4    Sakamoto, N.5
  • 39
    • 77955642188 scopus 로고    scopus 로고
    • Lipins: Multifunctional lipid metabolism proteins
    • Csaki LS, Reue K (2010) Lipins: multifunctional lipid metabolism proteins. Annu Rev Nutr 30: 257-272.
    • (2010) Annu Rev Nutr , vol.30 , pp. 257-272
    • Csaki, L.S.1    Reue, K.2
  • 41
    • 38149072281 scopus 로고    scopus 로고
    • Adipose tissue lipin-1 expression is correlated with peroxisome proliferator-activated receptor alpha gene expression and insulin sensitivity in healthy young men
    • Donkor J, Sparks LM, Xie H, Smith SR, Reue K (2008) Adipose tissue lipin-1 expression is correlated with peroxisome proliferator-activated receptor alpha gene expression and insulin sensitivity in healthy young men. J Clin Endocrinol Metab 93: 233-239.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 233-239
    • Donkor, J.1    Sparks, L.M.2    Xie, H.3    Smith, S.R.4    Reue, K.5
  • 42
    • 48849083595 scopus 로고    scopus 로고
    • Potential role of lipin-1 in exerciseinduced mitochondrial biogenesis
    • Higashida K, Higuchi M, Terada S (2008) Potential role of lipin-1 in exerciseinduced mitochondrial biogenesis. Biochem Biophys Res Commun 374: 587-591.
    • (2008) Biochem Biophys Res Commun , vol.374 , pp. 587-591
    • Higashida, K.1    Higuchi, M.2    Terada, S.3
  • 43
    • 84869832324 scopus 로고    scopus 로고
    • Principles of exercise physiology: Responses to acute exercise and long-term adaptations to training
    • Rivera-Brown AM, Frontera WR (2012) Principles of exercise physiology: responses to acute exercise and long-term adaptations to training. PM R 4: 797-804.
    • (2012) PM R , vol.4 , pp. 797-804
    • Rivera-Brown, A.M.1    Frontera, W.R.2
  • 47
    • 84865975344 scopus 로고    scopus 로고
    • 11beta-Hydroxysteroid dehydrogenase type 1: Relevance of its modulation in the pathophysiology of obesity, the metabolic syndrome and type 2 diabetes mellitus
    • Pereira CD, Azevedo I, Monteiro R, Martins MJ (2012) 11beta- Hydroxysteroid dehydrogenase type 1: relevance of its modulation in the pathophysiology of obesity, the metabolic syndrome and type 2 diabetes mellitus. Diabetes Obes Metab 14: 869-881.
    • (2012) Diabetes Obes Metab , vol.14 , pp. 869-881
    • Pereira, C.D.1    Azevedo, I.2    Monteiro, R.3    Martins, M.J.4
  • 48
    • 16844366165 scopus 로고    scopus 로고
    • Occludin: Structure, function and regulation
    • DOI 10.1016/j.addr.2005.01.009, Adhesion Proteins in Cellular Tight Junctions: Critical Components in the Modulation of Paracellular Permeability
    • Feldman GJ, Mullin JM, Ryan MP (2005) Occludin: structure, function and regulation. Adv Drug Deliv Rev 57: 883-917. (Pubitemid 40488109)
    • (2005) Advanced Drug Delivery Reviews , vol.57 , Issue.6 , pp. 883-917
    • Feldman, G.J.1    Mullin, J.M.2    Ryan, M.P.3
  • 49
    • 84882334135 scopus 로고    scopus 로고
    • Age-associated remodeling of the intestinal epithelial barrier
    • Tran L, Greenwood-Van Meerveld B (2013) Age-associated remodeling of the intestinal epithelial barrier. J Gerontol A Biol Sci Med Sci 68: 1045-1056.
    • (2013) J Gerontol A Biol Sci Med Sci , vol.68 , pp. 1045-1056
    • Tran, L.1    Greenwood-Van Meerveld, B.2
  • 50
    • 84878475974 scopus 로고    scopus 로고
    • Early Exercise Protects the Blood-Brain Barrier from Ischemic Brain Injury via the Regulation of MMP- 9 and Occludin in Rats
    • Zhang Y, Zhang P, Shen X, Tian S, Wu Y, et al. (2013) Early Exercise Protects the Blood-Brain Barrier from Ischemic Brain Injury via the Regulation of MMP- 9 and Occludin in Rats. Int J Mol Sci 14: 11096-11112.
    • (2013) Int J Mol Sci , vol.14 , pp. 11096-11112
    • Zhang, Y.1    Zhang, P.2    Shen, X.3    Tian, S.4    Wu, Y.5
  • 53
    • 84856110031 scopus 로고    scopus 로고
    • The role of neurexins in schizophrenia and autistic spectrum disorder
    • Reichelt AC, Rodgers RJ, Clapcote SJ (2012) The role of neurexins in schizophrenia and autistic spectrum disorder. Neuropharmacology 62: 1519-1526.
    • (2012) Neuropharmacology , vol.62 , pp. 1519-1526
    • Reichelt, A.C.1    Rodgers, R.J.2    Clapcote, S.J.3
  • 54
    • 79960000787 scopus 로고    scopus 로고
    • Genome-wide investigation of rare structural variants identifies VIPR2 as a new candidate gene for schizophrenia
    • Nieratschker V, Meyer-Lindenberg A, Witt SH (2011) Genome-wide investigation of rare structural variants identifies VIPR2 as a new candidate gene for schizophrenia. Expert Rev Neurother 11: 937-941.
    • (2011) Expert Rev Neurother , vol.11 , pp. 937-941
    • Nieratschker, V.1    Meyer-Lindenberg, A.2    Witt, S.H.3
  • 55
    • 84859239823 scopus 로고    scopus 로고
    • Myofibrillar myopathy caused by a mutation in the motor domain of mouse MyHC IIb
    • Kurapati R, McKenna C, Lindqvist J, Williams D, Simon M, et al. (2012) Myofibrillar myopathy caused by a mutation in the motor domain of mouse MyHC IIb. Hum Mol Genet 21: 1706-1724.
    • (2012) Hum Mol Genet , vol.21 , pp. 1706-1724
    • Kurapati, R.1    McKenna, C.2    Lindqvist, J.3    Williams, D.4    Simon, M.5
  • 56
    • 84862829155 scopus 로고    scopus 로고
    • Memory enhancement: Consolidation, reconsolidation and insulin-like growth factor 2
    • Alberini CM, Chen DY (2012) Memory enhancement: consolidation, reconsolidation and insulin-like growth factor 2. Trends Neurosci 35: 274-283.
    • (2012) Trends Neurosci , vol.35 , pp. 274-283
    • Alberini, C.M.1    Chen, D.Y.2
  • 57
    • 34447289392 scopus 로고    scopus 로고
    • Molecular genetics of human growth hormone, insulin-like growth factors and their pathways in common disease
    • DOI 10.1007/s00439-007-0378-3
    • Rodriguez S, Gaunt TR, Day IN (2007) Molecular genetics of human growth hormone, insulin-like growth factors and their pathways in common disease. Hum Genet 122: 1-21. (Pubitemid 47040569)
    • (2007) Human Genetics , vol.122 , Issue.1 , pp. 1-21
    • Rodriguez, S.1    Gaunt, T.R.2    Day, I.N.M.3
  • 59
    • 78751642080 scopus 로고    scopus 로고
    • Identification of a novel small molecule targeting UQCRB of mitochondrial complex III and its antiangiogenic activity
    • Jung HJ, Kim KH, Kim ND, Han G, Kwon HJ (2011) Identification of a novel small molecule targeting UQCRB of mitochondrial complex III and its antiangiogenic activity. Bioorg Med Chem Lett 21: 1052-1056.
    • (2011) Bioorg Med Chem Lett , vol.21 , pp. 1052-1056
    • Jung, H.J.1    Kim, K.H.2    Kim, N.D.3    Han, G.4    Kwon, H.J.5
  • 61
    • 79956215013 scopus 로고    scopus 로고
    • Insig2 is overexpressed in pancreatic cancer and its expression is induced by hypoxia
    • Kayashima T, Nakata K, Ohuchida K, Ueda J, Shirahane K, et al. (2011) Insig2 is overexpressed in pancreatic cancer and its expression is induced by hypoxia. Cancer Sci 102: 1137-1143.
    • (2011) Cancer Sci , vol.102 , pp. 1137-1143
    • Kayashima, T.1    Nakata, K.2    Ohuchida, K.3    Ueda, J.4    Shirahane, K.5
  • 62
    • 0035102208 scopus 로고    scopus 로고
    • Oxidative stress and protection against reactive oxygen species in the pre-implantation embryo and its surroundings
    • DOI 10.1093/humupd/7.2.175
    • Guerin P, El Mouatassim S, Menezo Y (2001) Oxidative stress and protection against reactive oxygen species in the pre-implantation embryo and its surroundings. Hum Reprod Update 7: 175-189. (Pubitemid 32208497)
    • (2001) Human Reproduction Update , vol.7 , Issue.2 , pp. 175-189
    • Guerin, P.1    El Mouatassim, S.2    Menezo, Y.3
  • 63
    • 0033672337 scopus 로고    scopus 로고
    • Antioxidant pyruvate inhibits cardiac formation of reactive oxygen species through changes in redox state
    • Bassenge E, Sommer O, Schwemmer M, Bunger R (2000) Antioxidant pyruvate inhibits cardiac formation of reactive oxygen species through changes in redox state. Am J Physiol Heart Circ Physiol 279: H2431-2438.
    • (2000) Am J Physiol Heart Circ Physiol , vol.279
    • Bassenge, E.1    Sommer, O.2    Schwemmer, M.3    Bunger, R.4
  • 65
    • 67650218858 scopus 로고
    • Malonate inhibition of oxidations in the Krebs tricarboxylic acid cycle
    • Pardee AB, Potter VR (1949) Malonate inhibition of oxidations in the Krebs tricarboxylic acid cycle. J Biol Chem 178: 241-250.
    • (1949) J Biol Chem , vol.178 , pp. 241-250
    • Pardee, A.B.1    Potter, V.R.2
  • 68
    • 77955610464 scopus 로고    scopus 로고
    • Could exercise metabolomics pave the way for gymnomimetics?
    • Burke MF, Dunbar RL, Rader DJ (2010) Could exercise metabolomics pave the way for gymnomimetics? Sci Transl Med 2: 41ps35.
    • (2010) Sci Transl Med , vol.2
    • Burke, M.F.1    Dunbar, R.L.2    Rader, D.J.3


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