Adipocyte-specific deficiency of Janus kinase (JAK) 2 in mice impairs lipolysis and increases body weight, and leads to insulin resistance with ageing

Diabetologia

Volumn 57, Issue 5, 2014, Pages 1016-1026

  Shi, Sally Yu ^a,b   Luk, Cynthia T ^a,b   Brunt, Jara J ^a,b   Sivasubramaniyam, Tharini ^a,b   Lu, Shun Yan ^a   Schroer, Stephanie A ^a   Woo, Minna ^a,b,c  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

Adipocyte; Glucose homeostasis; JAK2; Janus kinase 2; Metabolism; Obesity

Indexed keywords

ADIPOCYTOKINE; CRE RECOMBINASE; CYTOKINE; GROWTH HORMONE; HORMONE; ISOPRENALINE; JANUS KINASE 2; LEPTIN; STAT PROTEIN; JAK2 PROTEIN, MOUSE;

ADIPOCYTE; ADIPOSE TISSUE; AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; AP2 GENE; ARTICLE; BODY WEIGHT; CELL FUNCTION; CONTROLLED STUDY; CYTOKINE RELEASE; ENERGY EXPENDITURE; FEMALE; GENE EXPRESSION; GLUCOSE METABOLISM; INSULIN RESISTANCE; KNOCKOUT MOUSE; LIPID METABOLISM; LIPOLYSIS; LOXP SITE; MALE; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; ANIMAL; BODY COMPOSITION; CYTOLOGY; GLUCOSE TOLERANCE TEST; METABOLISM;

ADIPOCYTES; ADIPOKINES; ADIPOSITY; AGING; ANIMALS; BODY COMPOSITION; BODY WEIGHT; CYTOKINES; FEMALE; GLUCOSE TOLERANCE TEST; INSULIN RESISTANCE; JANUS KINASE 2; LIPOLYSIS; MALE; MICE; MICE, KNOCKOUT; OBESITY; PROMOTER REGIONS, GENETIC;

EID: 84898599467     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-014-3185-0     Document Type: Article

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