Effects of leukemia inhibitory factor on 3T3-L1 adipocytes

Journal of Endocrinology

Volumn 185, Issue 3, 2005, Pages 485-496

  Hogan, Jessica C ^a   Stephens, Jacqueline M ^a  

^a LOUISIANA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN DELTA; CYTOKINE; FATTY ACID SYNTHASE; GLUCOSE; GLYCOPROTEIN GP 130; INSULIN; LEUKEMIA INHIBITORY FACTOR; LIPID; MESSENGER RNA; STAT1 PROTEIN; STAT3 PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; SUPPRESSOR OF CYTOKINE SIGNALING 3; TRIACYLGLYCEROL;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL MATURATION; CELL STRAIN 3T3; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG BINDING SITE; ENZYME INHIBITION; GENE EXPRESSION; GLUCOSE TRANSPORT; INSULIN RESISTANCE; LIPOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; UPREGULATION;

3T3-L1 CELLS; ADIPOCYTES; ANIMALS; CCAAT-ENHANCER-BINDING PROTEINS; CELL DIFFERENTIATION; DNA-BINDING PROTEINS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GENE EXPRESSION; GLUCOSE; INSULIN; INTERLEUKIN-6; LEUKEMIA INHIBITORY FACTOR; MICE; REPRESSOR PROTEINS; RNA, MESSENGER; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRIGLYCERIDES;

EID: 21244465925     PISSN: 00220795     EISSN: None     Source Type: Journal    
DOI: 10.1677/joe.1.05980     Document Type: Article

References (41)

1. Aubert J, Dessolini S, Belmont N, Li M, McKenzie FR, Staccini L, Villageois P, Barhanin B, Vernallis A, Smith AG, Ailhaud G & Dani C 1999 Leukemia inhibitory factor and its receptor promote adipocyte differentiation via the mitogen-activated protein kinase cascade. Journal of Biological Chemistry 274 24965-24972.
2. Auernhammer CJ, Bousquet C & Melmed S 1999 Autoregulation of pituitary corticotroph SOCS3 expression: characterization of the murine SOCS3 promoter. PNAS 96 6964-6969.
3. Bastard JP, Jardel C, Bruckert E, Blondy P, Capeau J, Laville M, Vidal H & Hainque B 2000 Elevated levels of interleukin 6 are reduced in serum and subcutaneous adipose tissue of obese women after weight loss. Journal of Clinical Endocrinology and Metabolism 85 3338-3342.
4. Baumann H, Ziegler SF, Mosley B, Morella KK, Pajovic S & Gearing DP 1993 Reconstitution of the response to leukemia inhibitory factor, oncostatin M, and ciliary neurotrophic factor in hepatoma cells. Journal of Biological Chemistry 268 8414-8417.
5. Bennett MK, Lopez JM, Sanchez HB & Osborne TF 1995 Sterol regulation of fatty acid synthase promoter. Coordinate feedback regulation of two major lipid pathways. Journal of Biological Chemistry 270 25578-25583.
6. Butzkueven H, Zhang JG, Soilu-Hanninen M, Hochrein H, Chionh F, Shipham KA, Emery B, Turnley AM, Petratos S, Ernst M, Bartlett PF & Kilpatrick TJ 2002 LIF receptor signaling limits immune-mediated demyelination by enhancing oligodendrocyte survival. Nature Medicine 8 613-619.
7. Darlington GJ, Ross SE & MacDougald OA 1998 The role of C/EBP genes in adipocyte differentiation. Journal of Biological Chemistry 273 30057-30060.
8. Dazai S, Akita S, Hirano A, Rashid MA, Naito S, Akino K & Fujii T 2000 Leukemia inhibitory factor enhances bone formation in calvarial bone defect. Journal of Craniofacial Surgery 11 513-520.
9. Gimble JM, Wanker F, Wang CS, Bass H, Wu X, Kelly K, Yancopolous GD & Hill MR 1994 Regulation of bone marrow stromal cell differentiation by cytokines whose receptors share the gp130 protein. Journal of Cellular Biochemistry 54 122-133.
10. Greenwel P, Tanaka S, Penkov D, Zhang W, Olive M, Moll J, Vinson C, Di Liberto M & Ramirez F 2000 Tumor necrosis factor alpha inhibits type I collagen synthesis through repressive CCAAT/enhancer-binding proteins. Molecular and Cellular Biology 20 912-918.
11. 2-macroglobulin gene. PNAS 87 2364-2368.
12. Horton JD, Goldstein JL & Brown MS 2002 SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. Journal of Clinical Investigation 109 1125-1131.
13. Hungness ES, Luo GJ, Pitts TA, Sun X, Robb BW, Hershko D & Hasselgren PO 2002 Transcription factors C/EBP-beta and -delta regulate IL-6 production in IL-1 beta-stimulated human enterocytes. Journal of Cell Physiology 192 64-70.
14. Hutt JA, O'Rourke JP & DeWille J 2000 Signal transducer and activator of transcription 3 activates CCAAT enhancer-binding protein δ gene transcription in G0 growth-arrested mouse mammary epithelial cells and in involuting mouse mammary gland. Journal of Biological Chemistry 275 29123-29131.
15. Kishimoto T, Akira S, Narazaki M & Taga T 1995 Interleukin-6 family of cytokines and gp130. Blood 86 1243-1254.
16. Krebs DL & Hilton DJ 2001 SOCS proteins: negative regulators of cytokine signaling. Stem Cells 19 378-387.
17. Kurebayashi S, Sumitani S, Kasayama S, Jetten AM & Hirose T 2001 TNFα inhibits 3T3-L1 adipocyte differentiation without downregulating the expression of C/EBPβ or δ. Endocrine Journal 48 249-253.
18. Laemmli UK 1970 Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227 680-685.
19. Lane MD, Tang QQ & Jiang MS 1999 Role of the CCAAT enhancer binding proteins (C/EBPs) in adipocyte differentiation. Biochemical and Biophysical Research Communications 266 677-683.
20. MacDougald OA, Cornelius P, Lin FT, Chen SS & Lane MD 1994 Glucocorticoids reciprocally regulate expression of the CCAAT/enhancer-binding protein α and δ genes in 3T3-L1 adipocytes and white adipose tissue, Journal of Biological Chemistry 269 19041-19047.
21. MacDougald OA, Cornelius P, Liu R & Lane MD 1995 Insulin regulates transcription of the CCAAT/enhancer binding protein (C/EBP) α, β, and δ genes in fully-differentiated 3T3-L1 adipocytes. Journal of Biological Chemistry 270 647-654.
22. Marshall MK, Doerrler W, Feingold KR & Grunfeld C 1994 Leukemia inhibitory factor induces changes in lipid metabolism in cultured adipocytes. Endocrinology 135 141-147.
23. Mori M, Yamaguchi K & Abe K 1989 Purification of a lipoprotein lipase-inhibiting protein produced by a melanoma cell line associated with cancer cachexia. Biochemical and Biophysical Research Communications 160 1085-1092.
24. Murphy M, Reid K, Hilton DJ & Bartlett PF 1991 Generation of sensory neurons is stimulated by leukemia inhibitory factor. PNAS 88 3498-3501.
25. Ohsumi J, Sakakibara S, Yamaguchi J, Miyadai K, Yoshioka S, Fujiwara T, Horikoshi H & Serizawa N 1994 Troglitazone prevents the inhibitory effects of inflammatory cytokines on insulin-induced adipocyte differentiation in 3T3-L1 cells. Endocrinology 135 2279-2282.
26. Robinson RC, Grey LM, Staunton D, Vanjelecom H, Vernallis AB, Moreau JF, Stuart DI, Heath JK & Jones EY 1994 The crystal structure and biological function of leukemia inhibitory factor: implications for receptor binding. Cell 77 1101-1116.
27. Ruddy MJ, Wong GC, Liu XK, Yamamoto H, Kasayama S, Kirkwood KL & Gaffen SL 2004 Functional cooperation between interleukin-17 and tumor necrosis factor-alpha is mediated by CCAAT/enhancer binding protein family members. Journal of Biological Chemistry 279 2559-2567.
28. Schwaninger M, Peterson N, Prinz S, Sallmann S, Neher M & Spranger M 2000 Adenosine-induced expression of interleukin-6 in astrocytes through protein kinase A and NF-IL-6. Glia 31 51-58.
29. Shi H, Tzameli I, Bjorbaek C & Flier JS 2004 Suppressor of cytokine signaling 3 is a physiological regulator of adipocyte insulin signaling. Journal of Biological Chemistry 279 34733-34740.
30. Stephens JM & Pekala PH 1991 Transcriptional repression of the GLUT4 and C/EBP genes in 3T3-L1 adipocytes by tumor necrosis factor-alpha. Journal of Biological Chemistry 266 21839-21845.
31. Stephens JM & Pekala PH 1992 Transcriptional repression of C/EBPα and GLUT4 genes in 3T3-L1 adipocytes by tumor necrosis factor-alpha. Regulation is coordinate and independent of protein synthesis. Journal of Biological Chemistry 267 13580-13584.
32. Stephens JM, Lumpkin SJ & Fishman JB 1998 Activation of signal transducers and activators of transcription 1 and 3 by leukemia inhibitory factor, oncostatin-M, and interferon-γ in adipocytes. Journal of Biological Chemistry 273 31408-31416.
33. Stewart WC, Morrison RF, Young SL & Stephens JM 1999 Regulation of signal transducers and activators of transcription (STATs) by effectors of adipogenesis: coordinate regulation of STATs 1, 5A and 5B with peroxisome proliferator-activated receptor-γ and C/AAAT enhancer binding protein-α. Biochimica et Biophysica Acta 1452 188-196.
34. Sul HS & Wang D 1998 Nutritional and hormonal regulation of enzymes in fat synthesis: studies of fatty acid synthase and mitochondrial glycerol-3-phosphate acyltransferase gene transcription. Annual Reviews in Nutrition 18 331-351.
35. Tanaka T, Yoshida N, Kishimoto T & Akira S 1997 Defective adipocyte differentiation in mice lacking the C/EBPβ and/or C /EBPδ gene. EMBO Journal 16 7432-7443.
36. Wagner BJ, Hayes TE, Hoban CJ & Cochran BH 1990 The SIF binding element confers sis/PDGF inducibility onto the c-fos promoter. EMBO Journal 9 4477-4484.
37. Williams RL, Hilton DJ, Pease S, Willson TA, Stewart CL, Gearing DP, Wagner EF, Metcalf D, Nicola NA & Gough NM 1988 Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells. Nature 336 684-687.
38. Wollert KC, Taga T, Saito M, Narazaki M, Kishimoto T, Glembotski CC, Vernallis AB, Heath JK, Pennica D, Wood WI & Chien KR 1996 Cardiotrophin-1 activates a distinct form of cardiac muscle cell hypertrophy. Assembly of sarcomeric units in series via gp130/leukemia inhibitory factor receptor-dependent pathways. Journal of Biological Chemistry 271 9535-9545.
39. Yamada T, Tobita K, Osada S, Nishihara T & Imagawa M 1997 CCAAT/enhancer binding protein δ gene expression is mediated by APRF/STAT3. Journal of Biological Chemistry 121 731-738.
40. Zvonic S, Cornelius P, Stewart WJ, Mynatt RL & Stephens JM 2003 The regulation and activation of ciliary neurotrophic factor signaling proteins in adipocytes. Journal of Biological Chemistry 278 2228-2235.
41. Zvonic S, Hogan JC, Arbour-Reily P, Mynatt KL & Stephens JM 2004 Effects of cardiotrophin (CT-1) on adipocytes. Journal of Biological Chemistry 279 47572-47579.