Blood-nerve barrier dysfunction contributes to the generation of neuropathic pain and allows targeting of injured nerves for pain relief

Pain

Volumn 155, Issue 5, 2014, Pages 954-967

  Lim, Tony K Y ^a,b   Shi, Xiang Qun ^b   Martin, Hiliary Claire ^c   Huang, Hao ^b   Luheshi, Giamal ^d   Rivest, Serge ^e   Zhang, Ji ^a,b  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c MEMORIAL UNIVERSITY OF NEWFOUNDLAND   (Canada)

^d DOUGLAS MENTAL HEALTH UNIVERSITY INSTITUTE   (Canada)

^e UNIVERSITÉ LAVAL   (Canada)

Author keywords

Blood borne pronociceptive molecules; Blood nerve barrier; Macrophage infiltration; Nerve injury; Neuropathic pain; Vascular structure

Indexed keywords

FIBRINOGEN; LIPOPOLYSACCHARIDE; PROTOXIN; VASCULOTROPIN; VASCULOTROPIN A;

ALLODYNIA; ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD NERVE BARRIER; CARDIOVASCULAR SYSTEM; CHRONIC PAIN; CONTROLLED STUDY; IMMUNOCOMPETENT CELL; MACROPHAGE; MALE; MOUSE; NERVE INJURY; NERVE LIGATION; NEUROPATHIC PAIN; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SCIATIC NERVE; ANIMAL; C57BL MOUSE; COMPLICATION; HYPERALGESIA; METABOLISM; NEURALGIA; PAIN THRESHOLD; PATHOPHYSIOLOGY; PERIPHERAL NERVE INJURY; PHYSIOLOGY;

ANIMALS; BLOOD-NERVE BARRIER; HYPERALGESIA; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; NEURALGIA; PAIN MANAGEMENT; PAIN THRESHOLD; PERIPHERAL NERVE INJURIES; SCIATIC NERVE; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84898596374     PISSN: 03043959     EISSN: 18726623     Source Type: Journal    
DOI: 10.1016/j.pain.2014.01.026     Document Type: Article

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