New insights into roles of intermediate filament phosphorylation and progeria pathogenesis

IUBMB Life

Volumn 66, Issue 3, 2014, Pages 195-200

  Goto, Hidemasa ^a,b   Inagaki, Masaki ^a,b  

^a AICHI CANCER CENTER HOSPITAL   (Japan)

^b NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

aneuploidy; intermediate filament; mitosis; phosphorylation; protein kinase; senescence; vimentin

Indexed keywords

CYCLIN DEPENDENT KINASE 1; DESMIN; GLIAL FIBRILLARY ACIDIC PROTEIN; PHOSPHOPROTEIN PHOSPHATASE 1; VIMENTIN;

ACETYLATION; ANAPHASE; ANEUPLOIDY; CATARACT; CELL CULTURE; CELL CYCLE PHASE; CELL DIVISION; CELL SYNCHRONIZATION; CELLULAR DISTRIBUTION; CENTROSOME; CHROMOSOMAL INSTABILITY; CYTOKINESIS; CYTOLYSIS; EPITHELIUM CELL; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; INTERMEDIATE FILAMENT; MASS SPECTROMETRY; METAPHASE; METHYLATION; MITOSIS; MUTATION; NONHUMAN; PATHOGENESIS; PHENOTYPE; PREMATURE AGING; PROGERIA; PROMETAPHASE; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; PROTEIN PURIFICATION; REVIEW; TELOPHASE; TRANSIENT EXPRESSION;

EID: 84898546872     PISSN: 15216543     EISSN: 15216551     Source Type: Journal    
DOI: 10.1002/iub.1260     Document Type: Review

References (48)

1. Eriksson, J. E., Opal, P., and, Goldman, R. D., (1992) Intermediate filament dynamics. Curr. Opin. Cell Biol. 4, 99-104.
2. Fuchs, E., and, Weber, K., (1994) Intermediate filaments: structure, dynamics, function, and disease. Annu. Rev. Biochem. 63, 345-382.
3. Eriksson, J. E., Dechat, T., Grin, B., Helfand, B., Mendez, M., et al. (2009) Introducing intermediate filaments: from discovery to disease. J. Clin. Invest. 119, 1763-1771.
4. Parry, D. A., and, Steinert, P. M., (1992) Intermediate filament structure. Curr. Opin. Cell Biol. 4, 94-98.
5. Herrmann, H., and, Aebi, U., (2004) Intermediate filaments: molecular structure, assembly mechanism, and integration into functionally distinct intracellular scaffolds. Annu. Rev. Biochem. 73, 749-789.
6. Coulombe, P. A., Ma, L., Yamada, S., and, Wawersik, M., (2001) Intermediate filaments at a glance. J. Cell Sci. 114, 4345-4347.
7. Herrmann, H., Hesse, M., Reichenzeller, M., Aebi, U., and, Magin, T. M., (2003) Functional complexity of intermediate filament cytoskeletons: from structure to assembly to gene ablation. Int. Rev. Cytol. 223, 83-175.
8. Inagaki, M., Nakamura, Y., Takeda, M., Nishimura, T., and, Inagaki, N., (1994) Glial fibrillary acidic protein: dynamic property and regulation by phosphorylation. Brain Pathol. 4, 239-243.
9. Quinlan, R. A., Brenner, M., Goldman, J. E., and, Messing, A., (2007) GFAP and its role in Alexander disease. Exp. Cell Res. 313, 2077-2087.
10. Pekny, M., and, Lane, E. B., (2007) Intermediate filaments and stress. Exp. Cell Res. 313, 2244-2254.
11. Capetanaki, Y., Bloch, R. J., Kouloumenta, A., Mavroidis, M., and, Psarras, S., (2007) Muscle intermediate filaments and their links to membranes and membranous organelles. Exp. Cell Res. 313, 2063-2076.
12. Song, S., Landsbury, A., Dahm, R., Liu, Y., Zhang, Q., et al. (2009) Functions of the intermediate filament cytoskeleton in the eye lens. J. Clin. Invest. 119, 1837-1848.
13. Ivaska, J., Pallari, H. M., Nevo, J., and, Eriksson, J. E., (2007) Novel functions of vimentin in cell adhesion, migration, and signaling. Exp. Cell Res. 313, 2050-2062.
14. Starger, J. M., Brown, W. E., Goldman, A. E., and, Goldman, R. D., (1978) Biochemical and immunological analysis of rapidly purified 10-nm filaments from baby hamster kidney (BHK-21) cells. J. Cell Biol. 78, 93-109.
15. Soellner, P., Quinlan, R. A., and, Franke, W. W., (1985) Identification of a distinct soluble subunit of an intermediate filament protein: tetrameric vimentin from living cells. Proc. Natl. Acad. Sci. USA 82, 7929-7933.
16. Goto, H., Kosako, H., and, Inagaki, M., (2000) Regulation of intermediate filament organization during cytokinesis: possible roles of Rho-associated kinase. Microsc. Res. Tech. 49, 173-182.
17. Inagaki, M., Nishi, Y., Nishizawa, K., Matsuyama, M., and, Sato, C., (1987) Site-specific phosphorylation induces disassembly of vimentin filaments in vitro. Nature 328, 649-652.
18. Inagaki, M., Matsuoka, Y., Tsujimura, K., Ando, S., Tokui, T., et al. (1996) Dynamic property of intermediate filaments: regulation by phosphorylation. Bioessays 18, 481-487.
19. Omary, M. B., Ku, N. O., Tao, G. Z., Toivola, D. M., and, Liao, J., (2006) "Heads and tails" of intermediate filament phosphorylation: multiple sites and functional insights. Trends Biochem. Sci. 31, 383-394.
20. Hyder, C. L., Pallari, H. M., Kochin, V., and, Eriksson, J. E., (2008) Providing cellular signposts-post-translational modifications of intermediate filaments. FEBS Lett. 582, 2140-2148.
21. Sihag, R. K., Inagaki, M., Yamaguchi, T., Shea, T. B., and, Pant, H. C., (2007) Role of phosphorylation on the structural dynamics and function of types III and IV intermediate filaments. Exp. Cell Res. 313, 2098-2109.
22. Snider, N. T., and, Omary, M. B., (2014) Post-translational modifications of intermediate filament proteins: mechanisms and functions. Nat. Rev. Mol. Cell Biol. 15, 163-177.
23. Chou, Y. H., Bischoff, J. R., Beach, D., and, Goldman, R. D., (1990) Intermediate filament reorganization during mitosis is mediated by p34cdc2 phosphorylation of vimentin. Cell 62, 1063-1071.
24. Nagata, K., Izawa, I., and, Inagaki, M., (2001) A decade of site- and phosphorylation state-specific antibodies: recent advances in studies of spatiotemporal protein phosphorylation. Genes Cells 6, 653-664.
25. Izawa, I., and, Inagaki, M., (2006) Regulatory mechanisms and functions of intermediate filaments: a study using site- and phosphorylation state-specific antibodies. Cancer Sci. 97, 167-174.
26. Goto, H., and, Inagaki, M., (2007) Production of a site- and phosphorylation state-specific antibody. Nat. Protoc. 2, 2574-2581.
27. Sternberger, L. A., and, Sternberger, N. H., (1983) Monoclonal antibodies distinguish phosphorylated and nonphosphorylated forms of neurofilaments in situ. Proc. Natl. Acad. Sci. USA 80, 6126-6130.
28. Nishizawa, K., Yano, T., Shibata, M., Ando, S., Saga, S., et al. (1991) Specific localization of phosphointermediate filament protein in the constricted area of dividing cells. J. Biol. Chem. 266, 3074-3079.
29. Yano, T., Taura, C., Shibata, M., Hirono, Y., Ando, S., et al. (1991) A monoclonal antibody to the phosphorylated form of glial fibrillary acidic protein: application to a non-radioactive method for measuring protein kinase activities. Biochem. Biophys. Res. Commun. 175, 1144-1151.
30. Matsuoka, Y., Nishizawa, K., Yano, T., Shibata, M., Ando, S., et al. (1992) Two different protein kinases act on a different time schedule as glial filament kinases during mitosis. EMBO J. 11, 2895-2902.
31. Sekimata, M., Tsujimura, K., Tanaka, J., Takeuchi, Y., Inagaki, N., et al. (1996) Detection of protein kinase activity specifically activated at metaphase-anaphase transition. J. Cell Biol. 132, 635-641.
32. Kosako, H., Amano, M., Yanagida, M., Tanabe, K., Nishi, Y., et al. (1997) Phosphorylation of glial fibrillary acidic protein at the same sites by cleavage furrow kinase and Rho-associated kinase. J. Biol. Chem. 272, 10333-10336.
33. Kawajiri, A., Yasui, Y., Goto, H., Tatsuka, M., Takahashi, M., et al. (2003) Functional significance of the specific sites phosphorylated in desmin at cleavage furrow: Aurora-B may phosphorylate and regulate type III intermediate filaments during cytokinesis coordinatedly with Rho-kinase. Mol. Biol. Cell 14, 1489-1500.
34. Chou, Y. H., Ngai, K. L., and, Goldman, R., (1991) The regulation of intermediate filament reorganization in mitosis. p34cdc2 phosphorylates vimentin at a unique N-terminal site. J. Biol. Chem. 266, 7325-7328.
35. Kusubata, M., Tokui, T., Matsuoka, Y., Okumura, E., Tachibana, K., et al. (1992) p13suc1 suppresses the catalytic function of p34cdc2 kinase for intermediate filament proteins, in vitro. J. Biol. Chem. 267, 20937-20942.
36. Tsujimura, K., Ogawara, M., Takeuchi, Y., Imajoh-Ohmi, S., Ha, M. H., et al. (1994) Visualization and function of vimentin phosphorylation by cdc2 kinase during mitosis. J. Biol. Chem. 269, 31097-31106.
37. Yamaguchi, T., Goto, H., Yokoyama, T., Sillje, H., Hanisch, A., et al. (2005) Phosphorylation by Cdk1 induces Plk1-mediated vimentin phosphorylation during mitosis. J. Cell Biol. 171, 431-436.
38. Elia, A. E., Cantley, L. C., and, Yaffe, M. B., (2003) Proteomic screen finds pSer/pThr-binding domain localizing Plk1 to mitotic substrates. Science 299, 1228-1231.
39. Oguri, T., Inoko, A., Shima, H., Izawa, I., Arimura, N., et al. (2006) Vimentin-Ser82 as a memory phosphorylation site in astrocytes. Genes Cells 11, 531-540.
40. Takai, Y., Ogawara, M., Tomono, Y., Moritoh, C., Imajoh-Ohmi, S., et al. (1996) Mitosis-specific phosphorylation of vimentin by protein kinase C coupled with reorganization of intracellular membranes. J. Cell Biol. 133, 141-149.
41. Yasui, Y., Goto, H., Matsui, S., Manser, E., Lim, L., et al. (2001) Protein kinases required for segregation of vimentin filaments in mitotic process. Oncogene 20, 2868-2876.
42. Goto, H., Yasui, Y., Kawajiri, A., Nigg, E. A., Terada, Y., et al. (2003) Aurora-B regulates the cleavage furrow-specific vimentin phosphorylation in the cytokinetic process. J. Biol. Chem. 278, 8526-8530.
43. Yokoyama, T., Goto, H., Izawa, I., Mizutani, H., and, Inagaki, M., (2005) Aurora-B and Rho-kinase/ROCK, the two cleavage furrow kinases, independently regulate the progression of cytokinesis: possible existence of a novel cleavage furrow kinase phosphorylates ezrin/radixin/moesin (ERM). Genes Cells 10, 127-137.
44. Inada, H., Togashi, H., Nakamura, Y., Kaibuchi, K., Nagata, K., et al. (1999) Balance between activities of Rho kinase and type 1 protein phosphatase modulates turnover of phosphorylation and dynamics of desmin/vimentin filaments. J. Biol. Chem. 274, 34932-34939.
45. Inada, H., Goto, H., Tanabe, K., Nishi, Y., Kaibuchi, K., et al. (1998) Rho-associated kinase phosphorylates desmin, the myogenic intermediate filament protein, at unique amino-terminal sites. Biochem. Biophys. Res. Commun. 253, 21-25.
46. Yasui, Y., Amano, M., Nagata, K., Inagaki, N., Nakamura, H., et al. (1998) Roles of Rho-associated kinase in cytokinesis; mutations in Rho-associated kinase phosphorylation sites impair cytokinetic segregation of glial filaments. J. Cell Biol. 143, 1249-1258.
47. Matsuyama, M., Tanaka, H., Inoko, A., Goto, H., Yonemura, S., et al. (2013) Defect of mitotic vimentin phosphorylation causes microophthalmia and cataract via aneuploidy and senescence in lens epithelial cells. J. Biol Chem. 288, 35626-35635.
48. Ganem, N. J., Godinho, S. A., and, Pellman, D., (2009) A mechanism linking extra centrosomes to chromosomal instability. Nature 460, 278-282.