The synergistic effect of mizoribine and a direct renin inhibitor, aliskiren, on unilateral ureteral obstruction induced renal fibrosis in rats

Journal of Urology

Volumn 191, Issue 4, 2014, Pages 1139-1146

  Sakuraya, Koji ^a   Endo, Amane ^a   Someya, Tomonosuke ^a   Hirano, Daishi ^b   Murano, Yayoi ^a   Fujinaga, Shuichiro ^c   Ohtomo, Yoshiyuki ^a   Shimizu, Toshiaki ^a  

^a JUNTENDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c SAITAMA CHILDREN'S MEDICAL CENTER   (Japan)

Author keywords

aliskiren; bredinin; drug synergism; kidney; ureteral obstruction

Indexed keywords

ALISKIREN; ALPHA SMOOTH MUSCLE ACTIN; MESSENGER RNA; MIZORIBINE; MONOCYTE CHEMOTACTIC PROTEIN 1; OSTEOPONTIN; RENIN; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; DRUG POTENTIATION; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MALE; MONOCYTE; MYOFIBROBLAST; NONHUMAN; OBSTRUCTION-INDUCED RENAL FIBROSIS; PLASMA RENIN ACTIVITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; RENAL PROTECTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UNILATERAL URETERAL OBSTRUCTION; URETER OBSTRUCTION; ANIMAL TISSUE; DRUG EFFICACY; GENE EXPRESSION; KIDNEY; KIDNEY FIBROSIS; MONOTHERAPY; VASCULAR SMOOTH MUSCLE;

ALISKIREN; BREDININ; DRUG SYNERGISM; KIDNEY; URETERAL OBSTRUCTION;

AMIDES; ANIMALS; DRUG SYNERGISM; DRUG THERAPY, COMBINATION; FIBROSIS; FUMARATES; KIDNEY; MALE; RATS; RATS, SPRAGUE-DAWLEY; RENIN; RIBONUCLEOSIDES; TRANSFORMING GROWTH FACTOR BETA1; URETERAL OBSTRUCTION;

EID: 84898458065     PISSN: 00225347     EISSN: 15273792     Source Type: Journal    
DOI: 10.1016/j.juro.2013.10.053     Document Type: Article

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