A remote GATA2 hematopoietic enhancer drives leukemogenesis in inv(3)(q21;q26) by activating EVI1 expression

Cancer Cell

Volumn 25, Issue 4, 2014, Pages 415-427

  Yamazaki, Hiromi ^a   Suzuki, Mikiko ^a   Otsuki, Akihito ^a   Shimizu, Ritsuko ^a   Bresnick, Emery H ^c   Engel, James Douglas ^d   Yamamoto, Masayuki ^a,b  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

^c UNIVERSITY OF WISCONSIN   (United States)

^d UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRE RECOMBINASE; TRANSCRIPTION FACTOR GATA 2;

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; CELL EXPANSION; CELL POPULATION; CONTROLLED STUDY; EVI1 GENE; GENE; GENE ACTIVATION; GENE EXPRESSION; GENE IDENTIFICATION; GENE OVEREXPRESSION; HEMATOPOIETIC STEM CELL; LEUKEMIA CELL; LEUKEMOGENESIS; LOXP SITE; LYMPHATIC LEUKEMIA; MOUSE; MYELOID LEUKEMIA; NONHUMAN; PRIORITY JOURNAL; PROTO ONCOGENE; STEM CELL; TRANSGENIC MOUSE;

BACTERIA (MICROORGANISMS); MUS; MUS MUSCULUS;

ANIMALS; BASE SEQUENCE; CHROMOSOME INVERSION; CHROMOSOMES, HUMAN, PAIR 3; DNA-BINDING PROTEINS; GATA2 TRANSCRIPTION FACTOR; HEMATOPOIESIS; HUMANS; LEUKEMIA, MYELOID, ACUTE; MICE; MICE, TRANSGENIC; PROTO-ONCOGENES; TRANSCRIPTION FACTORS; TRANSFECTION; TRANSGENES; TRANSLOCATION, GENETIC;

EID: 84898420078     PISSN: 15356108     EISSN: 18783686     Source Type: Journal    
DOI: 10.1016/j.ccr.2014.02.008     Document Type: Article

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