-
1
-
-
75249086827
-
Ewing's sarcoma
-
20152770 10.1016/S1470-2045(09)70286-4
-
Balamuth NJ, Womer RB (2010) Ewing's sarcoma. Lancet Oncol 11(2):184-192
-
(2010)
Lancet Oncol
, vol.11
, Issue.2
, pp. 184-192
-
-
Balamuth, N.J.1
Womer, R.B.2
-
3
-
-
84875056487
-
Molecular pathogenesis and targeted therapeutics in Ewing sarcoma/primitive neuroectodermal tumours
-
3351706 22587874 10.1186/2045-3329-2-6
-
Kelleher FC, Thomas DM (2012) Molecular pathogenesis and targeted therapeutics in Ewing sarcoma/primitive neuroectodermal tumours. Clin Sarcoma Res 2(1):6
-
(2012)
Clin Sarcoma Res
, vol.2
, Issue.1
, pp. 6
-
-
Kelleher, F.C.1
Thomas, D.M.2
-
4
-
-
70349753195
-
Advances in Ewing's sarcoma research: Where are we now and what lies ahead?
-
19738075 10.1158/0008-5472.CAN-08-4041
-
Ordóñez JL, Osuna D, Herrero D, de Alava E, Madoz-Gúrpide J (2009) Advances in Ewing's sarcoma research: where are we now and what lies ahead? Cancer Res 69(18):7140-7150
-
(2009)
Cancer Res
, vol.69
, Issue.18
, pp. 7140-7150
-
-
Ordóñez, J.L.1
Osuna, D.2
Herrero, D.3
De Alava, E.4
Madoz-Gúrpide, J.5
-
5
-
-
0030862075
-
The Ewing family of tumors. Ewing's sarcoma and primitive neuroectodermal tumors
-
9286296 10.1016/S0031-3955(05)70541-1
-
Grier HE (1997) The Ewing family of tumors. Ewing's sarcoma and primitive neuroectodermal tumors. Pediatr Clin North Am 44:991
-
(1997)
Pediatr Clin North Am
, vol.44
, pp. 991
-
-
Grier, H.E.1
-
6
-
-
0020634618
-
Ewing's sarcoma of bone: Clinicopathologic aspects of 303 cases from the Intergroup Ewing's Sarcoma Study
-
6885037 10.1016/S0046-8177(83)80300-1
-
Kissane JM, Askin FB, Foulkes M, Stratton LB, Shirley SF (1983) Ewing's sarcoma of bone: clinicopathologic aspects of 303 cases from the Intergroup Ewing's Sarcoma Study. Hum Pathol 14:773
-
(1983)
Hum Pathol
, vol.14
, pp. 773
-
-
Kissane, J.M.1
Askin, F.B.2
Foulkes, M.3
Stratton, L.B.4
Shirley, S.F.5
-
7
-
-
84880576746
-
Prognostic factors and clinical outcome of patients with Ewing's sarcoma family of tumors in adults: Multicentric study of the Anatolian Society of Medical Oncology
-
23345116 10.1007/s12032-013-0469-z
-
Arpaci E, Yetisyigit T, Seker M, Uncu D, Uyeturk U, Oksuzoglu B, Demirci U, Coskun U, Kucukoner M, IsIkdogan A, Inanc M, Alkis N, Ozkan M (2013) Prognostic factors and clinical outcome of patients with Ewing's sarcoma family of tumors in adults: multicentric study of the Anatolian Society of Medical Oncology. Med Oncol 30(1):469
-
(2013)
Med Oncol
, vol.30
, Issue.1
, pp. 469
-
-
Arpaci, E.1
Yetisyigit, T.2
Seker, M.3
Uncu, D.4
Uyeturk, U.5
Oksuzoglu, B.6
Demirci, U.7
Coskun, U.8
Kucukoner, M.9
Isikdogan, A.10
Inanc, M.11
Alkis, N.12
Ozkan, M.13
-
8
-
-
70350150140
-
Critical signaling pathways in bone sarcoma: Candidates for therapeutic interventions
-
19840522 10.1007/s11912-009-0061-z
-
Geryk-Hall M, Hughes DP (2009) Critical signaling pathways in bone sarcoma: candidates for therapeutic interventions. Curr Oncol Rep 11(6):446-453
-
(2009)
Curr Oncol Rep
, vol.11
, Issue.6
, pp. 446-453
-
-
Geryk-Hall, M.1
Hughes, D.P.2
-
9
-
-
0014439475
-
Past failures and future possibilities in Ewing's sarcoma: Experimental and preliminary clinical results
-
5763249 10.1002/1097-0142(196901)23:1<161: AID-CNCR2820230121>3.0. CO;2-L
-
Johnson R, Humphreys SR (1969) Past failures and future possibilities in Ewing's sarcoma: experimental and preliminary clinical results. Cancer 23:161-166
-
(1969)
Cancer
, vol.23
, pp. 161-166
-
-
Johnson, R.1
Humphreys, S.R.2
-
10
-
-
84869447819
-
Randomized controlled trial of interval-compressed chemotherapy for the treatment of localized Ewing sarcoma: A report from the Children's Oncology Group
-
3494838 23091096 10.1200/JCO.2011.41.5703
-
Womer RB, West DC, Krailo MD, Dickman PS, Pawel BR, Grier HE, Marcus K, Sailer S, Healey JH, Dormans JP, Weiss AR (2012) Randomized controlled trial of interval-compressed chemotherapy for the treatment of localized Ewing sarcoma: a report from the Children's Oncology Group. J Clin Oncol 30:4148-4154
-
(2012)
J Clin Oncol
, vol.30
, pp. 4148-4154
-
-
Womer, R.B.1
West, D.C.2
Krailo, M.D.3
Dickman, P.S.4
Pawel, B.R.5
Grier, H.E.6
Marcus, K.7
Sailer, S.8
Healey, J.H.9
Dormans, J.P.10
Weiss, A.R.11
-
11
-
-
0037080272
-
Survival after recurrence of Ewing tumors: The St Jude Children's Research Hospital experience, 1979-1999
-
11900241 10.1002/cncr.10192
-
Rodriguez-Galindo C, Billups CA, Kun LE, Rao BN, Pratt CB, Merchant TE, Santana VM, Pappo AS (2002) Survival after recurrence of Ewing tumors: the St Jude Children's Research Hospital experience, 1979-1999. Cancer 94:561-569
-
(2002)
Cancer
, vol.94
, pp. 561-569
-
-
Rodriguez-Galindo, C.1
Billups, C.A.2
Kun, L.E.3
Rao, B.N.4
Pratt, C.B.5
Merchant, T.E.6
Santana, V.M.7
Pappo, A.S.8
-
12
-
-
0034955685
-
Treatment strategies for metastatic Ewing's sarcoma
-
11435062 10.1016/S0959-8049(01)00131-9
-
Pinkerton CR, Bataillard A, Guillo S, Oberlin O, Fervers B, Philip T (2001) Treatment strategies for metastatic Ewing's sarcoma. Eur J Cancer 37:1338-1344
-
(2001)
Eur J Cancer
, vol.37
, pp. 1338-1344
-
-
Pinkerton, C.R.1
Bataillard, A.2
Guillo, S.3
Oberlin, O.4
Fervers, B.5
Philip, T.6
-
13
-
-
84883165709
-
Overview of cancer stem cells (CSCs) and mechanisms of their regulation: Implications for cancer therapy
-
23744710
-
Bao B, Ahmad A, Azmi AS, Ali S, Sarkar FH (2013) Overview of cancer stem cells (CSCs) and mechanisms of their regulation: implications for cancer therapy. Curr Protoc Pharmacol 14(Unit14):25
-
(2013)
Curr Protoc Pharmacol
, vol.14
, Issue.UNIT14
, pp. 25
-
-
Bao, B.1
Ahmad, A.2
Azmi, A.S.3
Ali, S.4
Sarkar, F.H.5
-
14
-
-
76749139548
-
Do stem-like cells play a role in drug resistance of sarcomas?
-
20132001 10.1586/era.09.184
-
Honoki K (2010) Do stem-like cells play a role in drug resistance of sarcomas? Expert Rev Anticancer Ther 10(2):261-270
-
(2010)
Expert Rev Anticancer Ther
, vol.10
, Issue.2
, pp. 261-270
-
-
Honoki, K.1
-
15
-
-
84866483877
-
Targeting CSCs within the tumor microenvironment for cancer therapy: A potential role of mesenchymal stem cells
-
22877147 10.1517/14728222.2012.714774
-
Bao B, Ahmad A, Li Y, Azmi AS, Ali S, Banerjee S, Kong D, Sarkar FH (2012) Targeting CSCs within the tumor microenvironment for cancer therapy: a potential role of mesenchymal stem cells. Expert Opin Ther Targets 16(10):1041-1054
-
(2012)
Expert Opin Ther Targets
, vol.16
, Issue.10
, pp. 1041-1054
-
-
Bao, B.1
Ahmad, A.2
Li, Y.3
Azmi, A.S.4
Ali, S.5
Banerjee, S.6
Kong, D.7
Sarkar, F.H.8
-
16
-
-
84862297325
-
Sarcoma stem cells: Do we know what we are looking for?
-
3357604 22654552 10.1155/2012/291705
-
Trucco M, Loeb D (2012) Sarcoma stem cells: do we know what we are looking for? Sarcoma 2012:291705
-
(2012)
Sarcoma
, vol.2012
, pp. 291705
-
-
Trucco, M.1
Loeb, D.2
-
17
-
-
84887448247
-
Salient features of mesenchymal stem cells-implications for Ewing sarcoma modeling
-
3580960 23443465 10.3389/fonc.2013.00024
-
Monument MJ, Bernthal NM, Randall RL (2013) Salient features of mesenchymal stem cells-implications for Ewing sarcoma modeling. Front Oncol 3:24
-
(2013)
Front Oncol
, vol.3
, pp. 24
-
-
Monument, M.J.1
Bernthal, N.M.2
Randall, R.L.3
-
18
-
-
78349237776
-
Mesenchymal stem cells and the origin of Ewing's sarcoma
-
Lin PP, Wang Y, Lozano G (2011) Mesenchymal stem cells and the origin of Ewing's sarcoma. Sarcoma 2011:276463
-
(2011)
Sarcoma
, vol.2011
, pp. 276463
-
-
Lin, P.P.1
Wang, Y.2
Lozano, G.3
-
19
-
-
77952893906
-
CD133 expression in chemo-resistant Ewing sarcoma cells
-
2851692 20346143 10.1186/1471-2407-10-116
-
Jiang X, Gwye Y, Russell D, Cao C, Douglas D, Hung L, Kovar H, Triche TJ, Lawlor ER (2010) CD133 expression in chemo-resistant Ewing sarcoma cells. BMC Cancer 10:116
-
(2010)
BMC Cancer
, vol.10
, pp. 116
-
-
Jiang, X.1
Gwye, Y.2
Russell, D.3
Cao, C.4
Douglas, D.5
Hung, L.6
Kovar, H.7
Triche, T.J.8
Lawlor, E.R.9
-
20
-
-
71849094172
-
Potential for therapeutic targeting of tumor stem cells
-
19860850 10.1111/j.1349-7006.2009.01371.x
-
Saini V, Shoemaker RH (2010) Potential for therapeutic targeting of tumor stem cells. Cancer Sci 101(1):16-21
-
(2010)
Cancer Sci
, vol.101
, Issue.1
, pp. 16-21
-
-
Saini, V.1
Shoemaker, R.H.2
-
21
-
-
20044367805
-
Ewing sarcomas with p53 mutation or p16/p14ARF homozygous deletion: A highly lethal subset associated with poor chemoresponse
-
15659501 10.1200/JCO.2005.02.081
-
Huang HY, Illei PB, Zhao Z, Mazumdar M, Huvos AG, Healey JH, Wexler LH, Gorlick R, Meyers P, Ladanyi M (2005) Ewing sarcomas with p53 mutation or p16/p14ARF homozygous deletion: a highly lethal subset associated with poor chemoresponse. J Clin Oncol 23(3):548-558
-
(2005)
J Clin Oncol
, vol.23
, Issue.3
, pp. 548-558
-
-
Huang, H.Y.1
Illei, P.B.2
Zhao, Z.3
Mazumdar, M.4
Huvos, A.G.5
Healey, J.H.6
Wexler, L.H.7
Gorlick, R.8
Meyers, P.9
Ladanyi, M.10
-
22
-
-
78650730395
-
Clinicopathological significance of cell cycle regulation markers in a large series of genetically confirmed Ewing's sarcoma family of tumors
-
20473914 10.1002/ijc.25424
-
Lopez-Guerrero JA, Machado I, Scotlandi K, Noguera R, Pellin A, Navarro S, Serra M, Calabuig-Fariñas S, Picci P, Llombart-Bosch A (2011) Clinicopathological significance of cell cycle regulation markers in a large series of genetically confirmed Ewing's sarcoma family of tumors. Int J Cancer 128:1139-1150
-
(2011)
Int J Cancer
, vol.128
, pp. 1139-1150
-
-
Lopez-Guerrero, J.A.1
Machado, I.2
Scotlandi, K.3
Noguera, R.4
Pellin, A.5
Navarro, S.6
Serra, M.7
Calabuig-Fariñas, S.8
Picci, P.9
Llombart-Bosch, A.10
-
23
-
-
84890114204
-
MicroRNAs in Ewing sarcoma
-
3610014 23543617 10.3389/fonc.2013.00065
-
Dylla L, Moore C, Jedlicka P (2013) MicroRNAs in Ewing sarcoma. Front Oncol 3:65
-
(2013)
Front Oncol
, vol.3
, pp. 65
-
-
Dylla, L.1
Moore, C.2
Jedlicka, P.3
-
24
-
-
84874449515
-
MiR-125b develops chemoresistance in Ewing sarcoma/primitive neuroectodermal tumor
-
3599506 23497288 10.1186/1475-2867-13-21
-
Iida K, Fukushi J, Matsumoto Y, Oda Y, Takahashi Y, Fujiwara T, Fujiwara-Okada Y, Hatano M, Nabashima A, Kamura S, Iwamoto Y (2013) miR-125b develops chemoresistance in Ewing sarcoma/primitive neuroectodermal tumor. Cancer Cell Int 13(1):21
-
(2013)
Cancer Cell Int
, vol.13
, Issue.1
, pp. 21
-
-
Iida, K.1
Fukushi, J.2
Matsumoto, Y.3
Oda, Y.4
Takahashi, Y.5
Fujiwara, T.6
Fujiwara-Okada, Y.7
Hatano, M.8
Nabashima, A.9
Kamura, S.10
Iwamoto, Y.11
-
25
-
-
84856732824
-
MiR-34a predicts survival of Ewing's sarcoma patients and directly influences cell chemo-sensitivity and malignancy
-
21960059 10.1002/path.3007
-
Nakatani F, Ferracin M, Manara MC, Ventura S, Del Monaco V, Ferrari S, Alberghini M, Grilli A, Knuutila S, Schaefer KL, Mattia G, Negrini M, Picci P, Serra M, Scotlandi K (2012) miR-34a predicts survival of Ewing's sarcoma patients and directly influences cell chemo-sensitivity and malignancy. J Pathol 226(5):796-805
-
(2012)
J Pathol
, vol.226
, Issue.5
, pp. 796-805
-
-
Nakatani, F.1
Ferracin, M.2
Manara, M.C.3
Ventura, S.4
Del Monaco, V.5
Ferrari, S.6
Alberghini, M.7
Grilli, A.8
Knuutila, S.9
Schaefer, K.L.10
Mattia, G.11
Negrini, M.12
Picci, P.13
Serra, M.14
Scotlandi, K.15
-
26
-
-
84865304256
-
EWS/FLI1 regulates EYA3 in Ewing sarcoma via modulation of miRNA-708, resulting in increased cell survival and chemoresistance
-
3432289 22723308 10.1158/1541-7786.MCR-12-0086
-
Robin TP, Smith A, McKinsey E, Reaves L, Jedlicka P, Ford HL (2012) EWS/FLI1 regulates EYA3 in Ewing sarcoma via modulation of miRNA-708, resulting in increased cell survival and chemoresistance. Mol Cancer Res 10(8):1098-1108
-
(2012)
Mol Cancer Res
, vol.10
, Issue.8
, pp. 1098-1108
-
-
Robin, T.P.1
Smith, A.2
McKinsey, E.3
Reaves, L.4
Jedlicka, P.5
Ford, H.L.6
-
27
-
-
34547762804
-
Immunophenotypic profile of biomarkers related to anti-apoptotic and neural development pathways in the Ewing's family of tumors (EFT) and their therapeutic implications
-
17695539
-
Navarro S, Giraudo P, Karseladze AI, Smirnov A, Petrovichev N, Savelov N, Alvarado-Cabrero I, Llombart-Bosch A (2007) Immunophenotypic profile of biomarkers related to anti-apoptotic and neural development pathways in the Ewing's family of tumors (EFT) and their therapeutic implications. Anticancer Res 27(4B):2457-2463
-
(2007)
Anticancer Res
, vol.27
, Issue.4
, pp. 2457-2463
-
-
Navarro, S.1
Giraudo, P.2
Karseladze, A.I.3
Smirnov, A.4
Petrovichev, N.5
Savelov, N.6
Alvarado-Cabrero, I.7
Llombart-Bosch, A.8
-
28
-
-
84867946834
-
Survivin, a target to modulate the radiosensitivity of Ewing's sarcoma
-
23053158 10.1007/s00066-012-0223-z
-
Greve B, Sheikh-Mounessi F, Kemper B, Ernst I, Götte M, Eich HT (2012) Survivin, a target to modulate the radiosensitivity of Ewing's sarcoma. Strahlenther Onkol 188(11):1038-1047
-
(2012)
Strahlenther Onkol
, vol.188
, Issue.11
, pp. 1038-1047
-
-
Greve, B.1
Sheikh-Mounessi, F.2
Kemper, B.3
Ernst, I.4
Götte, M.5
Eich, H.T.6
-
29
-
-
79952230990
-
Down-regulation of XIAP by AEG35156 in paediatric tumour cells induces apoptosis and sensitises cells to cytotoxic agents
-
21286665
-
Holt SV, Brookes KE, Dive C, Makin GW (2011) Down-regulation of XIAP by AEG35156 in paediatric tumour cells induces apoptosis and sensitises cells to cytotoxic agents. Oncol Rep 25(4):1177-1181
-
(2011)
Oncol Rep
, vol.25
, Issue.4
, pp. 1177-1181
-
-
Holt, S.V.1
Brookes, K.E.2
Dive, C.3
Makin, G.W.4
-
30
-
-
0033530269
-
Fas-mediated apoptosis in Ewing's sarcoma cell lines by metalloproteinase inhibitors
-
10511596 10.1093/jnci/91.19.1678
-
Mitsiades N, Poulaki V, Leone A, Tsokos M (1999) Fas-mediated apoptosis in Ewing's sarcoma cell lines by metalloproteinase inhibitors. J Natl Cancer Inst 91(19):1678-1684
-
(1999)
J Natl Cancer Inst
, vol.91
, Issue.19
, pp. 1678-1684
-
-
Mitsiades, N.1
Poulaki, V.2
Leone, A.3
Tsokos, M.4
-
31
-
-
0028050582
-
Immunohistochemical detection of P-glycoprotein in Ewing's sarcoma and peripheral primitive neuroectodermal tumors before and after chemotherapy
-
7913576
-
Hijazi YM, Axiotis CA, Navarro S, Steinberg SM, Horowitz ME, Tsokos M (1994) Immunohistochemical detection of P-glycoprotein in Ewing's sarcoma and peripheral primitive neuroectodermal tumors before and after chemotherapy. Am J Clin Pathol 102(1):61-67
-
(1994)
Am J Clin Pathol
, vol.102
, Issue.1
, pp. 61-67
-
-
Hijazi, Y.M.1
Axiotis, C.A.2
Navarro, S.3
Steinberg, S.M.4
Horowitz, M.E.5
Tsokos, M.6
-
32
-
-
0030905994
-
Expression of multidrug resistance-associated protein gene in Ewing's sarcoma and malignant peripheral neuroectodermal tumor of bone
-
9177499 10.1007/BF01240323
-
Oda Y, Dockhorn-Dworniczak B, Jürgens H, Roessner A (1997) Expression of multidrug resistance-associated protein gene in Ewing's sarcoma and malignant peripheral neuroectodermal tumor of bone. J Cancer Res Clin Oncol 123(4):237-239
-
(1997)
J Cancer Res Clin Oncol
, vol.123
, Issue.4
, pp. 237-239
-
-
Oda, Y.1
Dockhorn-Dworniczak, B.2
Jürgens, H.3
Roessner, A.4
-
33
-
-
27944434891
-
Involvement of P-glycoprotein and MRP1 in resistance to cyclic tetrapeptide subfamily of histone deacetylase inhibitors in the drug-resistant osteosarcoma and Ewing's sarcoma cells
-
16049968 10.1002/ijc.21297
-
Okada T, Tanaka K, Nakatani F, Sakimura R, Matsunobu T, Li X, Hanada M, Nakamura T, Oda Y, Tsuneyoshi M, Iwamoto Y (2006) Involvement of P-glycoprotein and MRP1 in resistance to cyclic tetrapeptide subfamily of histone deacetylase inhibitors in the drug-resistant osteosarcoma and Ewing's sarcoma cells. Int J Cancer 118(1):90-97
-
(2006)
Int J Cancer
, vol.118
, Issue.1
, pp. 90-97
-
-
Okada, T.1
Tanaka, K.2
Nakatani, F.3
Sakimura, R.4
Matsunobu, T.5
Li, X.6
Hanada, M.7
Nakamura, T.8
Oda, Y.9
Tsuneyoshi, M.10
Iwamoto, Y.11
-
34
-
-
84884812845
-
The role of aldehyde dehydrogenase (ALDH) in cancer drug resistance
-
Januchowski R, Wojtowicz K, Zabel M (2013) The role of aldehyde dehydrogenase (ALDH) in cancer drug resistance. Biomed Pharmacother 67(7):669-680
-
(2013)
Biomed Pharmacother
, vol.67
, Issue.7
, pp. 669-680
-
-
Januchowski, R.1
Wojtowicz, K.2
Zabel, M.3
-
35
-
-
78649728590
-
High ALDH activity identifies chemotherapy-resistant Ewing's sarcoma stem cells that retain sensitivity to EWS-FLI1 inhibition
-
2978678 21085683 10.1371/journal.pone.0013943
-
Awad O, Yustein JT, Shah P, Gul N, Katuri V, O'Neill A, Kong Y, Brown ML, Toretsky JA, Loeb DM (2010) High ALDH activity identifies chemotherapy- resistant Ewing's sarcoma stem cells that retain sensitivity to EWS-FLI1 inhibition. PLoS One 5(11):e13943
-
(2010)
PLoS One
, vol.5
, Issue.11
, pp. 13943
-
-
Awad, O.1
Yustein, J.T.2
Shah, P.3
Gul, N.4
Katuri, V.5
O'Neill, A.6
Kong, Y.7
Brown, M.L.8
Toretsky, J.A.9
Loeb, D.M.10
-
36
-
-
35848931009
-
The mechanism of cross-resistance to proteasome inhibitor bortezomib and overcoming resistance in Ewing's family tumor cells
-
17786311
-
Nakamura T, Tanaka K, Matsunobu T, Okada T, Nakatani F, Sakimura R, Hanada M, Iwamoto Y (2007) The mechanism of cross-resistance to proteasome inhibitor bortezomib and overcoming resistance in Ewing's family tumor cells. Int J Oncol 31(4):803-811
-
(2007)
Int J Oncol
, vol.31
, Issue.4
, pp. 803-811
-
-
Nakamura, T.1
Tanaka, K.2
Matsunobu, T.3
Okada, T.4
Nakatani, F.5
Sakimura, R.6
Hanada, M.7
Iwamoto, Y.8
-
37
-
-
0642374221
-
The role of glutathione-S-transferase in anti-cancer drug resistance
-
14576844 10.1038/sj.onc.1206940
-
Townsend DM, Tew KD (2003) The role of glutathione-S-transferase in anti-cancer drug resistance. Oncogene 22(47):7369-7375
-
(2003)
Oncogene
, vol.22
, Issue.47
, pp. 7369-7375
-
-
Townsend, D.M.1
Tew, K.D.2
-
38
-
-
79960809400
-
Targeting glutathione-S transferase enzymes in musculoskeletal sarcomas: A promising therapeutic strategy
-
Pasello M, Manara MC, Michelacci F, Fanelli M, Hattinger CM, Nicoletti G, Landuzzi L, Lollini PL, Caccuri A, Picci P, Scotlandi K, Serra M (2011) Targeting glutathione-S transferase enzymes in musculoskeletal sarcomas: a promising therapeutic strategy. Anal Cell Pathol (Amst) 34(3):131-145
-
(2011)
Anal Cell Pathol (Amst)
, vol.34
, Issue.3
, pp. 131-145
-
-
Pasello, M.1
Manara, M.C.2
Michelacci, F.3
Fanelli, M.4
Hattinger, C.M.5
Nicoletti, G.6
Landuzzi, L.7
Lollini, P.L.8
Caccuri, A.9
Picci, P.10
Scotlandi, K.11
Serra, M.12
-
39
-
-
0038352146
-
Cytochrome P450 CYP3A4/5 expression as a biomarker of outcome in osteosarcoma
-
12829666 10.1200/JCO.2003.06.015
-
Dhaini HR, Thomas DG, Giordano TJ, Johnson TD, Biermann JS, Leu K, Hollenberg PF, Baker LH (2003) Cytochrome P450 CYP3A4/5 expression as a biomarker of outcome in osteosarcoma. J Clin Oncol 21(13):2481-2485
-
(2003)
J Clin Oncol
, vol.21
, Issue.13
, pp. 2481-2485
-
-
Dhaini, H.R.1
Thomas, D.G.2
Giordano, T.J.3
Johnson, T.D.4
Biermann, J.S.5
Leu, K.6
Hollenberg, P.F.7
Baker, L.H.8
-
40
-
-
36348970313
-
Targeted therapies in Ewing's sarcoma
-
17163152 10.1007/978-1-4020-5133-3-2
-
Scotlandi K (2006) Targeted therapies in Ewing's sarcoma. Adv Exp Med Biol 587:13-22
-
(2006)
Adv Exp Med Biol
, vol.587
, pp. 13-22
-
-
Scotlandi, K.1
-
41
-
-
84891590949
-
COG Ewing Sarcoma Biology Committee. Biomarkers in Ewing sarcoma: The Promise and Challenge of Personalized Medicine. A report from the Children's Oncology Group
-
3674398 23761859 10.3389/fonc.2013.00141
-
Shukla N, Schiffman J, Reed D, Davis IJ, Womer RB, Lessnick SL, Lawlor ER (2013) COG Ewing Sarcoma Biology Committee. Biomarkers in Ewing sarcoma: the Promise and Challenge of Personalized Medicine. A report from the Children's Oncology Group. Front Oncol 3:141
-
(2013)
Front Oncol
, vol.3
, pp. 141
-
-
Shukla, N.1
Schiffman, J.2
Reed, D.3
Davis, I.J.4
Womer, R.B.5
Lessnick, S.L.6
Lawlor, E.R.7
-
42
-
-
84867946225
-
The clinical use of biomarkers as prognostic factors in Ewing sarcoma
-
3351700 22587879 10.1186/2045-3329-2-7
-
van Maldegem AM, Hogendoorn PC, Hassan AB (2012) The clinical use of biomarkers as prognostic factors in Ewing sarcoma. Clin Sarcoma Res 2(1):7
-
(2012)
Clin Sarcoma Res
, vol.2
, Issue.1
, pp. 7
-
-
Van Maldegem, A.M.1
Hogendoorn, P.C.2
Hassan, A.B.3
-
43
-
-
62849105383
-
The insulin-like growth factor system and sarcomas
-
19148905 10.1002/path.2499
-
Rikhof B, de Jong S, Suurmeijer AJ, Meijer C, van der Graaf WT (2009) The insulin-like growth factor system and sarcomas. J Pathol 217(4):469-482
-
(2009)
J Pathol
, vol.217
, Issue.4
, pp. 469-482
-
-
Rikhof, B.1
De Jong, S.2
Suurmeijer, A.J.3
Meijer, C.4
Van Der Graaf, W.T.5
-
44
-
-
79959265311
-
Targeting the insulin-like growth factor 1 receptor in Ewing's sarcoma: Reality and expectations
-
3103989 21647361 10.1155/2011/402508
-
Olmos D, Martins AS, Jones RL, Alam S, Scurr M, Judson IR (2011) Targeting the insulin-like growth factor 1 receptor in Ewing's sarcoma: reality and expectations. Sarcoma 2011:402508
-
(2011)
Sarcoma
, vol.2011
, pp. 402508
-
-
Olmos, D.1
Martins, A.S.2
Jones, R.L.3
Alam, S.4
Scurr, M.5
Judson, I.R.6
-
45
-
-
33644816649
-
The molecular mechanisms responsible for resistance to ET-743 (Trabectidin; Yondelis) in the Ewing's sarcoma cell line, TC-71
-
16273217
-
Manara MC, Perdichizzi S, Serra M, Pierini R, Benini S, Hattinger CM, Astolfi A, Bagnati R, D'Incalci M, Picci P, Scotlandi K (2005) The molecular mechanisms responsible for resistance to ET-743 (Trabectidin; Yondelis) in the Ewing's sarcoma cell line, TC-71. Int J Oncol 27(6):1605-1616
-
(2005)
Int J Oncol
, vol.27
, Issue.6
, pp. 1605-1616
-
-
Manara, M.C.1
Perdichizzi, S.2
Serra, M.3
Pierini, R.4
Benini, S.5
Hattinger, C.M.6
Astolfi, A.7
Bagnati, R.8
D'Incalci, M.9
Picci, P.10
Scotlandi, K.11
-
46
-
-
67649389647
-
Development of IGF-IR inhibitors in pediatric sarcomas
-
19508836 10.1007/s11912-009-0043-1
-
Kolb EA, Gorlick R (2009) Development of IGF-IR inhibitors in pediatric sarcomas. Curr Oncol Rep 11(4):307-313
-
(2009)
Curr Oncol Rep
, vol.11
, Issue.4
, pp. 307-313
-
-
Kolb, E.A.1
Gorlick, R.2
-
47
-
-
77953641778
-
Biological rationale and current clinical experience with anti-insulin-like growth factor 1 receptor monoclonal antibodies in treating sarcoma: Twenty years from the bench to the bedside
-
20526094 10.1097/PPO.0b013e3181dbebf9
-
Olmos D, Tan DS, Jones RL, Judson IR (2010) Biological rationale and current clinical experience with anti-insulin-like growth factor 1 receptor monoclonal antibodies in treating sarcoma: twenty years from the bench to the bedside. Cancer J 16(3):183-194
-
(2010)
Cancer J
, vol.16
, Issue.3
, pp. 183-194
-
-
Olmos, D.1
Tan, D.S.2
Jones, R.L.3
Judson, I.R.4
-
48
-
-
84874547199
-
Insulin-like growth factor 1 receptor as a therapeutic target in Ewing sarcoma: Lack of consistent upregulation or recurrent mutation and a review of the clinical trial literature
-
3569907 23431249
-
O'Neill A, Shah N, Zitomersky N, Ladanyi M, Shukla N, Uren A, Loeb D, Toretsky J (2013) Insulin-like growth factor 1 receptor as a therapeutic target in Ewing sarcoma: lack of consistent upregulation or recurrent mutation and a review of the clinical trial literature. Sarcoma 2013:450478
-
(2013)
Sarcoma
, vol.2013
, pp. 450478
-
-
O'Neill, A.1
Shah, N.2
Zitomersky, N.3
Ladanyi, M.4
Shukla, N.5
Uren, A.6
Loeb, D.7
Toretsky, J.8
-
49
-
-
84865585349
-
Identification of common and distinctive mechanisms of resistance to different anti-IGF-IR agents in Ewing's sarcoma
-
22798295 10.1210/me.2012-1142
-
Garofalo C, Mancarella C, Grilli A, Manara MC, Astolfi A, Marino MT, Conte A, Sigismund S, Carè A, Belfiore A, Picci P, Scotlandi K (2012) Identification of common and distinctive mechanisms of resistance to different anti-IGF-IR agents in Ewing's sarcoma. Mol Endocrinol 26(9):1603-1616
-
(2012)
Mol Endocrinol
, vol.26
, Issue.9
, pp. 1603-1616
-
-
Garofalo, C.1
Mancarella, C.2
Grilli, A.3
Manara, M.C.4
Astolfi, A.5
Marino, M.T.6
Conte, A.7
Sigismund, S.8
Carè, A.9
Belfiore, A.10
Picci, P.11
Scotlandi, K.12
-
50
-
-
79958863370
-
Efficacy of and resistance to anti-IGF-1R therapies in Ewing's sarcoma is dependent on insulin receptor signaling
-
21278796 10.1038/onc.2010.640
-
Garofalo C, Manara MC, Nicoletti G, Marino MT, Lollini PL, Astolfi A, Pandini G, López-Guerrero JA, Schaefer KL, Belfiore A, Picci P, Scotlandi K (2011) Efficacy of and resistance to anti-IGF-1R therapies in Ewing's sarcoma is dependent on insulin receptor signaling. Oncogene 30(24):2730-2740
-
(2011)
Oncogene
, vol.30
, Issue.24
, pp. 2730-2740
-
-
Garofalo, C.1
Manara, M.C.2
Nicoletti, G.3
Marino, M.T.4
Lollini, P.L.5
Astolfi, A.6
Pandini, G.7
López-Guerrero, J.A.8
Schaefer, K.L.9
Belfiore, A.10
Picci, P.11
Scotlandi, K.12
-
51
-
-
84862572950
-
Expression of therapeutic targets in Ewing sarcoma family tumors
-
22196127 10.1016/j.humpath.2011.09.001
-
Ahmed AA, Sherman AK, Pawel BR (2012) Expression of therapeutic targets in Ewing sarcoma family tumors. Hum Pathol 43(7):1077-1083
-
(2012)
Hum Pathol
, vol.43
, Issue.7
, pp. 1077-1083
-
-
Ahmed, A.A.1
Sherman, A.K.2
Pawel, B.R.3
-
52
-
-
84861019279
-
MAPK/ERK signaling in osteosarcomas, Ewing sarcomas and chondrosarcomas: Therapeutic implications and future directions
-
3345255 22577336 10.1155/2012/404810
-
Chandhanayingyong C, Kim Y, Staples JR, Hahn C, Lee FY (2012) MAPK/ERK signaling in osteosarcomas, Ewing sarcomas and chondrosarcomas: therapeutic implications and future directions. Sarcoma 2012:404810
-
(2012)
Sarcoma
, vol.2012
, pp. 404810
-
-
Chandhanayingyong, C.1
Kim, Y.2
Staples, J.R.3
Hahn, C.4
Lee, F.Y.5
-
53
-
-
84898056800
-
Crosstalk between IGF-1R and other tumor promoting pathways
-
Liu C, Zhang Z, Tang H, Jiang Z, You L, Lia Y (2013) Crosstalk between IGF-1R and other tumor promoting pathways. Curr Pharm Des 19:1-10
-
(2013)
Curr Pharm des
, vol.19
, pp. 1-10
-
-
Liu, C.1
Zhang, Z.2
Tang, H.3
Jiang, Z.4
You, L.5
Lia, Y.6
-
54
-
-
84879591354
-
Type 1 insulin-like growth factor receptor targeted therapies in pediatric cancer
-
3563098 23383402 10.3389/fonc.2013.00009
-
Wagner MJ, Maki RG (2013) Type 1 insulin-like growth factor receptor targeted therapies in pediatric cancer. Front Oncol 3:9
-
(2013)
Front Oncol
, vol.3
, pp. 9
-
-
Wagner, M.J.1
Maki, R.G.2
-
55
-
-
84880019478
-
ERBB4 confers metastatic capacity in Ewing sarcoma
-
3721475 23681745 10.1002/emmm.201202343
-
Mendoza-Naranjo A, El-Naggar A, Wai DH, Mistry P, Lazic N, Ayala FR, da Cunha IW, Rodriguez-Viciana P, Cheng H, Tavares Guerreiro Fregnani JH, Reynolds P, Arceci RJ, Nicholson A, Triche TJ, Soares FA, Flanagan AM, Wang YZ, Strauss SJ, Sorensen PH (2013) ERBB4 confers metastatic capacity in Ewing sarcoma. EMBO Mol Med 5(7):1019-1034
-
(2013)
EMBO Mol Med
, vol.5
, Issue.7
, pp. 1019-1034
-
-
Mendoza-Naranjo, A.1
El-Naggar, A.2
Wai, D.H.3
Mistry, P.4
Lazic, N.5
Ayala, F.R.6
Da Cunha, I.W.7
Rodriguez-Viciana, P.8
Cheng, H.9
Tavares Guerreiro Fregnani, J.H.10
Reynolds, P.11
Arceci, R.J.12
Nicholson, A.13
Triche, T.J.14
Soares, F.A.15
Flanagan, A.M.16
Wang, Y.Z.17
Strauss, S.J.18
Sorensen, P.H.19
-
56
-
-
84863547465
-
The human phosphotyrosine signaling network: Evolution and hotspots of hijacking in cancer
-
3396364 22194470 10.1101/gr.128819.111
-
Li L, Tibiche C, Fu C, Kaneko T, Moran MF, Schiller MR, Li SS, Wang E (2012) The human phosphotyrosine signaling network: evolution and hotspots of hijacking in cancer. Genome Res 22(7):1222-1230
-
(2012)
Genome Res
, vol.22
, Issue.7
, pp. 1222-1230
-
-
Li, L.1
Tibiche, C.2
Fu, C.3
Kaneko, T.4
Moran, M.F.5
Schiller, M.R.6
Li, S.S.7
Wang, E.8
-
57
-
-
84857671060
-
Tumor heterogeneity: Mechanisms and bases for a reliable application of molecular marker design
-
3292002 22408433 10.3390/ijms13021951
-
Diaz-Cano SalvadorJ (2012) Tumor heterogeneity: mechanisms and bases for a reliable application of molecular marker design. Int J Mol Sci 13(2):1951-2011
-
(2012)
Int J Mol Sci
, vol.13
, Issue.2
, pp. 1951-2011
-
-
Diaz-Cano, S.1
-
58
-
-
84875211731
-
Cancer heterogeneity: Implications for targeted therapeutics
-
3593543 23299535 10.1038/bjc.2012.581
-
Fisher R, Pusztai L, Swanton C (2013) Cancer heterogeneity: implications for targeted therapeutics. Br J Cancer 108(3):479-485
-
(2013)
Br J Cancer
, vol.108
, Issue.3
, pp. 479-485
-
-
Fisher, R.1
Pusztai, L.2
Swanton, C.3
-
59
-
-
70350227313
-
The insulin-like growth factor-1 receptor-targeting antibody, CP-751,871, suppresses tumor-derived VEGF and synergizes with rapamycin in models of childhood sarcoma
-
3003871 19789339 10.1158/0008-5472.CAN-09-1693
-
Kurmasheva RT, Dudkin L, Billups C, Debelenko LV, Morton CL, Houghton PJ (2009) The insulin-like growth factor-1 receptor-targeting antibody, CP-751,871, suppresses tumor-derived VEGF and synergizes with rapamycin in models of childhood sarcoma. Cancer Res 69(19):7662-7671
-
(2009)
Cancer Res
, vol.69
, Issue.19
, pp. 7662-7671
-
-
Kurmasheva, R.T.1
Dudkin, L.2
Billups, C.3
Debelenko, L.V.4
Morton, C.L.5
Houghton, P.J.6
-
60
-
-
84860506226
-
Insulin growth factor-receptor (IGF-1R) antibody cixutumumab combined with the mTOR inhibitor temsirolimus in patients with refractory Ewing's sarcoma family tumors
-
22465830 10.1158/1078-0432.CCR-12-0061
-
Naing A, LoRusso P, Fu S, Hong DS, Anderson P, Benjamin RS, Ludwig J, Chen HX, Doyle LA, Kurzrock R (2012) Insulin growth factor-receptor (IGF-1R) antibody cixutumumab combined with the mTOR inhibitor temsirolimus in patients with refractory Ewing's sarcoma family tumors. Clin Cancer Res 18(9):2625-2631
-
(2012)
Clin Cancer Res
, vol.18
, Issue.9
, pp. 2625-2631
-
-
Naing, A.1
Lorusso, P.2
Fu, S.3
Hong, D.S.4
Anderson, P.5
Benjamin, R.S.6
Ludwig, J.7
Chen, H.X.8
Doyle, L.A.9
Kurzrock, R.10
-
61
-
-
84881087888
-
How to escape the cancer attractor: Rationale and limitations of multi-target drugs
-
Huang S, Kauffman S (2013) How to escape the cancer attractor: rationale and limitations of multi-target drugs. Semin Cancer Biol 23(4):270-278
-
(2013)
Semin Cancer Biol
, vol.23
, Issue.4
, pp. 270-278
-
-
Huang, S.1
Kauffman, S.2
-
62
-
-
70349330663
-
Cancer attractors: A systems view of tumors from a gene network dynamics and developmental perspective
-
2754594 19595782 10.1016/j.semcdb.2009.07.003
-
Huang S, Ernberg I, Kauffman S (2009) Cancer attractors: a systems view of tumors from a gene network dynamics and developmental perspective. Semin Cell Dev Biol 20(7):869-876
-
(2009)
Semin Cell Dev Biol
, vol.20
, Issue.7
, pp. 869-876
-
-
Huang, S.1
Ernberg, I.2
Kauffman, S.3
-
63
-
-
84881109934
-
Cancer-related networks: A help to understand, predict and change malignant transformation
-
Csermely P, Korcsmáros T (2013) Cancer-related networks: a help to understand, predict and change malignant transformation. Semin Cancer Biol 23(4):209-212
-
(2013)
Semin Cancer Biol
, vol.23
, Issue.4
, pp. 209-212
-
-
Csermely P, K.1
-
64
-
-
84867649825
-
Ewing's sarcoma: Overcoming the therapeutic plateau
-
3893930 22742646
-
Subbiah V, Kurzrock R (2012) Ewing's sarcoma: overcoming the therapeutic plateau. Discov Med 13(73):405-415
-
(2012)
Discov Med
, vol.13
, Issue.73
, pp. 405-415
-
-
Subbiah, V.1
Kurzrock, R.2
|