-
1
-
-
0038492517
-
A global transcriptional regulatory role for c-Myc in Burkitt's lymphoma cells
-
Li Z, Van Calcar S, Qu C, Cavenee WK, Zhang MQ, Ren B. A global transcriptional regulatory role for c-Myc in Burkitt's lymphoma cells. Proc Natl Acad Sci USA 2003; 100:8164-8169.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 8164-8169
-
-
Li, Z.1
Van Calcar, S.2
Qu, C.3
Cavenee, W.K.4
Zhang, M.Q.5
Ren, B.6
-
2
-
-
0027327313
-
Binding of myc proteins to canonical and noncanonical DNA sequences
-
Blackwell TK, Huang J, Ma A, et al. Binding of myc proteins to canonical and noncanonical DNA sequences. Mol Cell Biol 1993; 13:5216-5224.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 5216-5224
-
-
Blackwell, T.K.1
Huang, J.2
Ma, A.3
-
3
-
-
84867021989
-
Transcriptional amplification in tumor cells with elevated c-Myc
-
Lin CY, Loven J, Rahl PB, et al. Transcriptional amplification in tumor cells with elevated c-Myc. Cell 2012; 151:56-67.
-
(2012)
Cell
, vol.151
, pp. 56-67
-
-
Lin, C.Y.1
Loven, J.2
Rahl, P.B.3
-
4
-
-
84867010006
-
c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells
-
Nie Z, Hu G, Wei G, et al. c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells. Cell 2012; 151:68-79.
-
(2012)
Cell
, vol.151
, pp. 68-79
-
-
Nie, Z.1
Hu, G.2
Wei, G.3
-
5
-
-
57149096666
-
N-Myc regulates a widespread euchromatic program in the human genome partially independent of its role as a classical transcription factor
-
Cotterman R, Jin VX, Krig SR, et al. N-Myc regulates a widespread euchromatic program in the human genome partially independent of its role as a classical transcription factor. Cancer Res 2008; 68:9654-9662.
-
(2008)
Cancer Res
, vol.68
, pp. 9654-9662
-
-
Cotterman, R.1
Jin, V.X.2
Krig, S.R.3
-
6
-
-
33745558509
-
Myc influences global chromatin structure
-
Knoepfler PS, Zhang XY, Cheng PF, Gafken PR, Mcmahon SB, Eisenman RN. Myc influences global chromatin structure. EMBO J 2006; 25:2723-2734.
-
(2006)
EMBO J
, vol.25
, pp. 2723-2734
-
-
Knoepfler, P.S.1
Zhang, X.Y.2
Cheng, P.F.3
Gafken, P.R.4
Mcmahon, S.B.5
Eisenman, R.N.6
-
7
-
-
79955717501
-
Dissection of the oncogenic MYCN transcriptional network reveals a large set of clinically relevant cell cycle genes as drivers of neuroblastoma tumorigenesis
-
Murphy DM, Buckley PG, Bryan K, et al. Dissection of the oncogenic MYCN transcriptional network reveals a large set of clinically relevant cell cycle genes as drivers of neuroblastoma tumorigenesis. Mol Carcinog 2011; 50:403-411.
-
(2011)
Mol Carcinog
, vol.50
, pp. 403-411
-
-
Murphy, D.M.1
Buckley, P.G.2
Bryan, K.3
-
8
-
-
17744400301
-
N-myc enhances the expression of a large set of genes functioning in ribosome biogenesis and protein synthesis
-
Boon K, Caron HN, van Asperen R, et al. N-myc enhances the expression of a large set of genes functioning in ribosome biogenesis and protein synthesis. EMBO J 2001; 20:1383-1393.
-
(2001)
EMBO J
, vol.20
, pp. 1383-1393
-
-
Boon, K.1
Caron, H.N.2
van Asperen, R.3
-
9
-
-
0033968093
-
Gene-target recognition among members of the myc superfamily and implications for oncogenesis
-
O'hagan RC, Schreiber-Agus N, Chen K, et al. Gene-target recognition among members of the myc superfamily and implications for oncogenesis. Nat Genet 2000; 24:113-119.
-
(2000)
Nat Genet
, vol.24
, pp. 113-119
-
-
O'hagan, R.C.1
Schreiber-Agus, N.2
Chen, K.3
-
10
-
-
0030799791
-
An alternative pathway for gene regulation by Myc
-
Peukert K, Staller P, Schneider A, Carmichael G, Hanel F, Eilers M. An alternative pathway for gene regulation by Myc. EMBO J 1997; 16:5672-5686.
-
(1997)
EMBO J
, vol.16
, pp. 5672-5686
-
-
Peukert, K.1
Staller, P.2
Schneider, A.3
Carmichael, G.4
Hanel, F.5
Eilers, M.6
-
11
-
-
13444270415
-
Myc represses transcription through recruitment of DNA methyltransferase corepressor
-
Brenner C, Deplus R, Didelot C, et al. Myc represses transcription through recruitment of DNA methyltransferase corepressor. EMBO J 2005; 24:336-346.
-
(2005)
EMBO J
, vol.24
, pp. 336-346
-
-
Brenner, C.1
Deplus, R.2
Didelot, C.3
-
12
-
-
70350010350
-
Epigenetic silencing of the RASSF1A tumor suppressor gene through HOXB3-mediated induction of DNMT3B expression
-
Palakurthy RK, Wajapeyee N, Santra MK, et al. Epigenetic silencing of the RASSF1A tumor suppressor gene through HOXB3-mediated induction of DNMT3B expression. Mol Cell 2009; 36:219-230.
-
(2009)
Mol Cell
, vol.36
, pp. 219-230
-
-
Palakurthy, R.K.1
Wajapeyee, N.2
Santra, M.K.3
-
13
-
-
0022388606
-
Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas
-
Seeger RC, Brodeur GM, Sather H, et al. Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas. N Engl J Med 1985; 313:1111-1116.
-
(1985)
N Engl J Med
, vol.313
, pp. 1111-1116
-
-
Seeger, R.C.1
Brodeur, G.M.2
Sather, H.3
-
14
-
-
52949154642
-
High Myc pathway activity and low stage of neuronal differentiation associate with poor outcome in neuroblastoma
-
Fredlund E, Ringner M, Maris JM, Pahlman S. High Myc pathway activity and low stage of neuronal differentiation associate with poor outcome in neuroblastoma. Proc Natl Acad Sci USA 2008; 105:14094-14099.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 14094-14099
-
-
Fredlund, E.1
Ringner, M.2
Maris, J.M.3
Pahlman, S.4
-
15
-
-
57349120674
-
Aberrant methylation of candidate tumor suppressor genes in neuroblastoma
-
Hoebeeck J, Michels E, Pattyn F, et al. Aberrant methylation of candidate tumor suppressor genes in neuroblastoma. Cancer Lett 2009; 273:336-346.
-
(2009)
Cancer Lett
, vol.273
, pp. 336-346
-
-
Hoebeeck, J.1
Michels, E.2
Pattyn, F.3
-
16
-
-
33750824574
-
Frequent promoter hypermethylation of RASSF1A and CASP8 in neuroblastoma
-
Lazcoz P, Munoz J, Nistal M, Pestana A, Encio I, Castresana JS. Frequent promoter hypermethylation of RASSF1A and CASP8 in neuroblastoma. BMC Cancer 2006; 6:254.
-
(2006)
BMC Cancer
, vol.6
, pp. 254
-
-
Lazcoz, P.1
Munoz, J.2
Nistal, M.3
Pestana, A.4
Encio, I.5
Castresana, J.S.6
-
17
-
-
11144229611
-
Association of epigenetic inactivation of RASSF1A with poor outcome in human neuroblastoma
-
Yang Q, Zage P, Kagan D, et al. Association of epigenetic inactivation of RASSF1A with poor outcome in human neuroblastoma. Clin Cancer Res 2004; 10:8493-8500.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 8493-8500
-
-
Yang, Q.1
Zage, P.2
Kagan, D.3
-
18
-
-
34250633589
-
Methylation of CASP8, DCR2, and HIN-1 in neuroblastoma is associated with poor outcome
-
Yang Q, Kiernan CM, Tian Y, et al. Methylation of CASP8, DCR2, and HIN-1 in neuroblastoma is associated with poor outcome. Clin Cancer Res 2007; 13:3191-3197.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 3191-3197
-
-
Yang, Q.1
Kiernan, C.M.2
Tian, Y.3
-
19
-
-
13444270332
-
CpG island methylator phenotype is a strong determinant of poor prognosis in neuroblastomas
-
Abe M, Ohira M, Kaneda A, et al. CpG island methylator phenotype is a strong determinant of poor prognosis in neuroblastomas. Cancer Res 2005; 65:828-834.
-
(2005)
Cancer Res
, vol.65
, pp. 828-834
-
-
Abe, M.1
Ohira, M.2
Kaneda, A.3
-
20
-
-
4344688973
-
Clustering of gene hypermethylation associated with clinical risk groups in neuroblastoma
-
Alaminos M, Davalos V, Cheung NK, Gerald WL, Esteller M. Clustering of gene hypermethylation associated with clinical risk groups in neuroblastoma. J Natl Cancer Inst 2004; 96:1208-1219.
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 1208-1219
-
-
Alaminos, M.1
Davalos, V.2
Cheung, N.K.3
Gerald, W.L.4
Esteller, M.5
-
21
-
-
23944463325
-
Distinct CpG methylation profiles characterize different clinical groups of neuroblastic tumors
-
Banelli B, Gelvi I, Di Vinci A, et al. Distinct CpG methylation profiles characterize different clinical groups of neuroblastic tumors. Oncogene 2005; 24:5619-5628.
-
(2005)
Oncogene
, vol.24
, pp. 5619-5628
-
-
Banelli, B.1
Gelvi, I.2
Di Vinci, A.3
-
22
-
-
0029743372
-
Conditional expression of N-myc in human neuroblastoma cells increases expression of alpha-prothymosin and ornithine decarboxylase and accelerates progression into S-phase early after mitogenic stimulation of quiescent cells
-
Lutz W, Stohr M, Schurmann J, Wenzel A, Lohr A, Schwab M. Conditional expression of N-myc in human neuroblastoma cells increases expression of alpha-prothymosin and ornithine decarboxylase and accelerates progression into S-phase early after mitogenic stimulation of quiescent cells. Oncogene 1996; 13:803-812.
-
(1996)
Oncogene
, vol.13
, pp. 803-812
-
-
Lutz, W.1
Stohr, M.2
Schurmann, J.3
Wenzel, A.4
Lohr, A.5
Schwab, M.6
-
23
-
-
65549092592
-
Clusterin, a haploinsufficient tumor suppressor gene in neuroblastomas
-
Chayka O, Corvetta D, Dews M, et al. Clusterin, a haploinsufficient tumor suppressor gene in neuroblastomas. J Natl Cancer Inst 2009; 101:663-677.
-
(2009)
J Natl Cancer Inst
, vol.101
, pp. 663-677
-
-
Chayka, O.1
Corvetta, D.2
Dews, M.3
-
24
-
-
57849107571
-
Stabilization of N-Myc is a critical function of Aurora A in human neuroblastoma
-
Otto T, Horn S, Brockmann M, et al. Stabilization of N-Myc is a critical function of Aurora A in human neuroblastoma. Cancer Cell 2009; 15:67-78.
-
(2009)
Cancer Cell
, vol.15
, pp. 67-78
-
-
Otto, T.1
Horn, S.2
Brockmann, M.3
-
25
-
-
3142562321
-
Phorbol ester-induced translocation of PKC epsilon to the nucleus in fibroblasts: Identification of nuclear PKC epsilon-associating proteins
-
Xu TR, Rumsby MG. Phorbol ester-induced translocation of PKC epsilon to the nucleus in fibroblasts: Identification of nuclear PKC epsilon-associating proteins. FEBS Lett 2004; 570:20-24.
-
(2004)
FEBS Lett
, vol.570
, pp. 20-24
-
-
Xu, T.R.1
Rumsby, M.G.2
-
26
-
-
0026651978
-
Ethidium bromide provides a simple tool for identifying genuine DNA-independent protein associations
-
Lai JS, Herr W. Ethidium bromide provides a simple tool for identifying genuine DNA-independent protein associations. Proc Natl Acad Sci USA 1992; 89:6958-6962.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 6958-6962
-
-
Lai, J.S.1
Herr, W.2
-
27
-
-
0030825309
-
COBRA: A sensitive and quantitative DNA methylation assay
-
Xiong Z, Laird PW. COBRA: A sensitive and quantitative DNA methylation assay. Nucleic Acids Res 1997; 25:2532-2534.
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 2532-2534
-
-
Xiong, Z.1
Laird, P.W.2
-
28
-
-
33745700202
-
Genome-wide profiling of CpG methylation identifies novel targets of aberrant hypermethylation in myeloid leukemia
-
Gebhard C, Schwarzfischer L, Pham TH, et al. Genome-wide profiling of CpG methylation identifies novel targets of aberrant hypermethylation in myeloid leukemia. Cancer Res 2006; 66:6118-6128.
-
(2006)
Cancer Res
, vol.66
, pp. 6118-6128
-
-
Gebhard, C.1
Schwarzfischer, L.2
Pham, T.H.3
-
29
-
-
73649141296
-
Frequent long-range epigenetic silencing of protocadherin gene clusters on chromosome 5q31 in Wilms' tumor
-
Dallosso AR, Hancock AL, Szemes M, et al. Frequent long-range epigenetic silencing of protocadherin gene clusters on chromosome 5q31 in Wilms' tumor. PLoS Genet 2009; 5:e1000745.
-
(2009)
PLoS Genet
, vol.5
-
-
Dallosso, A.R.1
Hancock, A.L.2
Szemes, M.3
-
30
-
-
0033919595
-
DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters
-
Robertson KD, Ait-Si-Ali S, Yokochi T, Wade PA, Jones PL, Wolffe AP. DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters. Nat Genet 2000; 25:338-342.
-
(2000)
Nat Genet
, vol.25
, pp. 338-342
-
-
Robertson, K.D.1
Ait-Si-Ali, S.2
Yokochi, T.3
Wade, P.A.4
Jones, P.L.5
Wolffe, A.P.6
-
31
-
-
79952828836
-
Transcriptional repression: The dark side of myc
-
Herkert B, Eilers M. Transcriptional repression: The dark side of myc. Genes Cancer 2010; 1:580-586.
-
(2010)
Genes Cancer
, vol.1
, pp. 580-586
-
-
Herkert, B.1
Eilers, M.2
-
32
-
-
83055176409
-
GSTP1 hypermethylation is associated with reduced protein expression, aggressive disease and prognosis in neuroblastoma
-
Gumy-Pause F, Pardo B, Khoshbeen-Boudal M, et al. GSTP1 hypermethylation is associated with reduced protein expression, aggressive disease and prognosis in neuroblastoma. Genes Chromosomes Cancer 2011; 51:174-185.
-
(2011)
Genes Chromosomes Cancer
, vol.51
, pp. 174-185
-
-
Gumy-Pause, F.1
Pardo, B.2
Khoshbeen-Boudal, M.3
-
33
-
-
0033765517
-
Direct recruitment of N-myc to target gene promoters
-
Mac SM, D'cunha CA, Farnham PJ. Direct recruitment of N-myc to target gene promoters. Mol Carcinog 2000; 29:76-86.
-
(2000)
Mol Carcinog
, vol.29
, pp. 76-86
-
-
Mac, S.M.1
D'cunha, C.A.2
Farnham, P.J.3
-
34
-
-
34548693211
-
Dickkopf-1 is down-regulated by MYCN and inhibits neuroblastoma cell proliferation
-
Koppen A, Ait-Aissa R, Hopman S, et al. Dickkopf-1 is down-regulated by MYCN and inhibits neuroblastoma cell proliferation. Cancer Lett 2007; 256:218-228.
-
(2007)
Cancer Lett
, vol.256
, pp. 218-228
-
-
Koppen, A.1
Ait-Aissa, R.2
Hopman, S.3
-
35
-
-
39649085571
-
Dickkopf-3 expression is a marker for neuroblastic tumor maturation and is down-regulated by MYCN
-
Koppen A, Ait-Aissa R, Koster J, et al. Dickkopf-3 expression is a marker for neuroblastic tumor maturation and is down-regulated by MYCN. Int J Cancer 2008; 122:1455-1464.
-
(2008)
Int J Cancer
, vol.122
, pp. 1455-1464
-
-
Koppen, A.1
Ait-Aissa, R.2
Koster, J.3
-
36
-
-
39749144542
-
An N-Myc truncation analogous to c-Myc-S induces cell proliferation independently of transactivation but dependent on Myc homology box II
-
Cowling VH, Cole MD. An N-Myc truncation analogous to c-Myc-S induces cell proliferation independently of transactivation but dependent on Myc homology box II. Oncogene 2008; 27:1327-1332.
-
(2008)
Oncogene
, vol.27
, pp. 1327-1332
-
-
Cowling, V.H.1
Cole, M.D.2
-
37
-
-
76549105209
-
MYCN-regulated microRNAs repress estrogen receptor-alpha (ESR1) expression and neuronal differentiation in human neuroblastoma
-
Loven J, Zinin N, Wahlstrom T, et al. MYCN-regulated microRNAs repress estrogen receptor-alpha (ESR1) expression and neuronal differentiation in human neuroblastoma. Proc Natl Acad Sci USA 2010; 107:1553-1558.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 1553-1558
-
-
Loven, J.1
Zinin, N.2
Wahlstrom, T.3
-
38
-
-
19044380776
-
Loss of a FYN-regulated differentiation and growth arrest pathway in advanced stage neuroblastoma
-
Berwanger B, Hartmann O, Bergmann E, et al. Loss of a FYN-regulated differentiation and growth arrest pathway in advanced stage neuroblastoma. Cancer Cell 2002; 2:377-386.
-
(2002)
Cancer Cell
, vol.2
, pp. 377-386
-
-
Berwanger, B.1
Hartmann, O.2
Bergmann, E.3
-
39
-
-
55649123695
-
Distinct transcriptional MYCN/c-MYC activities are associated with spontaneous regression or malignant progression in neuroblastomas
-
Westermann F, Muth D, Benner A, et al. Distinct transcriptional MYCN/c-MYC activities are associated with spontaneous regression or malignant progression in neuroblastomas. Genome Biol 2008; 9:R150.
-
(2008)
Genome Biol
, vol.9
-
-
Westermann, F.1
Muth, D.2
Benner, A.3
-
40
-
-
0033006387
-
N-myc-dependent repression of ndr1, a gene identified by direct subtraction of whole mouse embryo cDNAs between wild type and N-myc mutant
-
Shimono A, Okuda T, Kondoh H. N-myc-dependent repression of ndr1, a gene identified by direct subtraction of whole mouse embryo cDNAs between wild type and N-myc mutant. Mech Dev 1999; 83:39-52.
-
(1999)
Mech Dev
, vol.83
, pp. 39-52
-
-
Shimono, A.1
Okuda, T.2
Kondoh, H.3
-
41
-
-
73449113904
-
Dnmt3/transcription factor interactions as crucial players in targeted DNA methylation
-
Hervouet E, Vallette FM, Cartron PF. Dnmt3/transcription factor interactions as crucial players in targeted DNA methylation. Epigenetics 2009; 4:487-499.
-
(2009)
Epigenetics
, vol.4
, pp. 487-499
-
-
Hervouet, E.1
Vallette, F.M.2
Cartron, P.F.3
-
42
-
-
84862224603
-
The RASSF gene family members RASSF5, RASSF6 and RASSF7 show frequent DNA methylation in neuroblastoma
-
Djos A, Martinsson T, Kogner P, Caren H. The RASSF gene family members RASSF5, RASSF6 and RASSF7 show frequent DNA methylation in neuroblastoma. Mol Cancer 2012; 11:40.
-
(2012)
Mol Cancer
, vol.11
, pp. 40
-
-
Djos, A.1
Martinsson, T.2
Kogner, P.3
Caren, H.4
-
43
-
-
45549095542
-
Myc-mediated transcriptional repression by recruitment of histone deacetylase
-
Kurland JF, Tansey WP. Myc-mediated transcriptional repression by recruitment of histone deacetylase. Cancer Res 2008; 68:3624-3629.
-
(2008)
Cancer Res
, vol.68
, pp. 3624-3629
-
-
Kurland, J.F.1
Tansey, W.P.2
-
44
-
-
77949689758
-
The Arf tumor suppressor protein inhibits Miz1 to suppress cell adhesion and induce apoptosis
-
Herkert B, Dwertmann A, Herold S, et al. The Arf tumor suppressor protein inhibits Miz1 to suppress cell adhesion and induce apoptosis. J Cell Biol 2010; 188:905-918.
-
(2010)
J Cell Biol
, vol.188
, pp. 905-918
-
-
Herkert, B.1
Dwertmann, A.2
Herold, S.3
-
45
-
-
79959433009
-
Co-localization of the oncogenic transcription factor MYCN and the DNA methyl binding protein MeCP2 at genomic sites in neuroblastoma
-
Murphy DM, Buckley PG, Das S, Watters KM, Bryan K, Stallings RL. Co-localization of the oncogenic transcription factor MYCN and the DNA methyl binding protein MeCP2 at genomic sites in neuroblastoma. PLoS ONE 2011; 6:e21436.
-
(2011)
PLoS ONE
, vol.6
-
-
Murphy, D.M.1
Buckley, P.G.2
Das, S.3
Watters, K.M.4
Bryan, K.5
Stallings, R.L.6
|