Expression of TRPV1 in rabbits and consuming hot pepper affects its body weight

Molecular Biology Reports

Volumn 39, Issue 7, 2012, Pages 7583-7589

  Yu, Qi ^a   Wang, Yanli ^a   Yu, Ying ^b   Li, Yafeng ^a   Zhao, Sihai ^a   Chen, Yulong ^a   Waqar, Ahmed Bilal ^b   Fan, Jianglin ^b   Liu, Enqi ^a  

^a MEDICAL SCHOOL OF XI AN JIAOTONG UNIVERSITY   (China)

^b UNIVERSITY OF YAMANASHI   (Japan)

Author keywords

Body weight; Expression and distribution; Hot pepper; Rabbit; TRPV1

Indexed keywords

CAPSAICIN; VANILLOID RECEPTOR 1;

ADRENAL GLAND; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; BRAIN; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; FOOD INTAKE; GENE EXPRESSION; KIDNEY; LIPID DIET; MALE; METABOLIC DISORDER; NONHUMAN; NUCLEOTIDE SEQUENCE; OBESITY; PEPPER; PHYLOGENY; PROTEIN EXPRESSION; PROTEIN FUNCTION; RABBIT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPLEEN; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ANIMALS; BODY WEIGHT; CAPSAICIN; CAPSICUM; DIET, HIGH-FAT; LIPID METABOLISM; MALE; MODELS, ANIMAL; OBESITY; PHYLOGENY; RABBITS; RNA, MESSENGER; SEQUENCE ALIGNMENT; TRPV CATION CHANNELS;

CAPSICUM FRUTESCENS; ORYCTOLAGUS CUNICULUS; RODENTIA;

EID: 84864279075     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-012-1592-1     Document Type: Article

References (35)

1. Szallasi A, Cortright DN, Blum CA, Eid SR (2007) The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept. Nat Rev Drug Discov 6(5):357-372 (Pubitemid 46705200)
2. Tominaga M, Tominaga T (2005) Structure and function of TRPV1. Pflugers Arch 451(1):143-150 (Pubitemid 41424917)
3. Szolcsanyi J (2004) Forty years in capsaicin research for sensory pharmacology and physiology. Neuropeptides 38(6):377-384 (Pubitemid 39572842)
4. Suri A, Szallasi A (2008) The emerging role of TRPV1 in diabetes and obesity. Trends Pharmacol Sci 29(1):29-36
5. Ching LC, Kou YR, Shyue SK, Su KH, Wei J, Cheng LC, Yu YB, Pan CC, Lee TS (2011) Molecular mechanisms of activation of endothelial nitric oxide synthase mediated by transient receptor potential vanilloid type 1. Cardiovasc Res 91(3): 492-501
6. Harper AG, Brownlow SL, Sage SO (2009) A role for TRPV1 in agonist-evoked activation of human platelets. J Thromb Haemost 7(2):330-338
7. Yang XR, Lin MJ, McIntosh LS, Sham JS (2006) Functional expression of transient receptor potential melastatin-and vanil-loid-related channels in pulmonary arterial and aortic smooth muscle. Am J Physiol Lung Cell Mol Physiol 290(6):L1267-L1276 (Pubitemid 43830872)
8. Kawada T, Hagihara KI, Iwai K (1986) Formation and metabolism of pungent principle of capsicum fruits-effects of capsaicin on lipid-metabolism in rats fed a high-fat diet. J Nutr 116(7): 1272-1278
9. Yanni AE (2004) The laboratory rabbit: an animal model of atherosclerosis research. Lab Anim 38(3):246-256 (Pubitemid 38962073)
10. Russell JC, Proctor SD (2006) Small animal models of cardiovascular disease: tools for the study of the roles of metabolic syndrome, dyslipidemia, and atherosclerosis. Cardiovasc Pathol 15(6):318-330 (Pubitemid 44755356)
11. Fan J, Watanabe T (2003) Transgenic rabbits as therapeutic protein bioreactors and human disease models. Pharmacol Ther 99(3):261-282 (Pubitemid 37311195)
12. Zhang C, Zheng H, Yu Q, Yang P, Li Y, Cheng F, Fan J, Liu E (2010) A practical method for quantifying atherosclerotic lesions in rabbits. J Comp Pathol 142(2-3):122-128
13. Kwon MJ, Song YS, Choi MS, Song YO (2003) Red pepper attenuates cholesteryl ester transfer protein activity and atherosclerosis in cholesterol-fed rabbits. Clin Chim Acta 332(1-2): 37-44
14. Cheng S, He S, Chen W, Wu Y (2009) Detection of capsaicin and dihydrocapsaicin content and analysis of pungency degree in different pepper genotypes. Nat Sci J Hainan Univ 27(1):38-42
15. Zheng H, Zhang C, Yang W, Wang Y, Lin Y, Yang P, Yu Q, Fan J, Liu E (2009) Fat and cholesterol diet induced lipid metabolic disorders and insulin resistance in rabbit. Exp Clin Endocrinol Diabetes 117(8):400-405
16. Liu E, Kitajima S, Higaki Y, Morimoto M, Sun H, Watanabe T, Yamada N, Fan J (2005) High lipoprotein lipase activity increases insulin sensitivity in transgenic rabbits. Metabolism 54(1): 132-138 (Pubitemid 39572468)
17. Zhang Y, Xiang B, Li YM, Wang Y, Wang X, Wang YN, Wu LL, Yu GY (2006) Expression and characteristics of vanilloid receptor 1 in the rabbit submandibular gland. Biochem Biophys Res Commun 345(1):467-473
18. Liang J, Liu E, Yu Y, Kitajima S, Koike T, Jin Y, Morimoto M, Hatakeyama K, Asada Y, Watanabe T, Sasaguri Y, Watanabe S, Fan J (2006) Macrophage metalloelastase accelerates the progression of atherosclerosis in transgenic rabbits. Circulation 113(16):1993-2001
19. Yu Q, Lin Y, Yang P, Wang Y, Zhao S, Fan J, Liu E (2011) C-reactive protein is associated with the progression of acute embolic stroke in rabbit model. J Thromb Thrombolysis Epub ahead of print
20. Thompson JD, Higgins DG, Gibson TJ (1994) CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res 22(22): 4673-4680 (Pubitemid 24354800)
21. Saitou N, Nei M (1987) The neighbor-joining method: a new method for reconstructing phylogenetic trees. Mol Biol Evol 4(4):406-425
22. Felsenstein J (1985) Confidence-limits on phylogenies-an approach using the bootstrap. Evolution 39(4):783-791
23. Starowicz K, Cristino L, Di Marzo V (2008) TRPV1 receptors in the central nervous system: potential for previously unforeseen therapeutic applications. Curr Pharm Des 14(1):42-54 (Pubitemid 351266983)
24. Leung FW (2008) Capsaicin-sensitive intestinal mucosal afferent mechanism and body fat distribution. Life Sci 83(1-2):1-5
25. Yang D, Luo Z, Ma S, Wong WT, Ma L, Zhong J, He H, Zhao Z, Cao T, Yan Z, Liu D, Arendshorst WJ, Huang Y, Tepel M, Zhu Z (2010) Activation of TRPV1 by dietary capsaicin improves endothelium-dependent vasorelaxation and prevents hypertension. Cell Metab 12(2):130-141
26. Eilers H, Lee SY, Hau CW, Logvinova A, Schumacher MA (2007) The rat vanilloid receptor splice variant VR.5'sv blocks TRPV1 activation. Neuroreport 18(10):969-973 (Pubitemid 46905167)
27. Hellwig N, Albrecht N, Harteneck C, Schultz G, Schaefer M (2005) Homo-and heteromeric assembly of TRPV channel sub-units. J Cell Sci 118(Pt 5):917-928 (Pubitemid 40484883)
28. Schumacher MA, Moff I, Sudanagunta SP, Levine JD (2000) Molecular cloning of an N-terminal splice variant of the capsaicin receptor. Loss of N-terminal domain suggests functional divergence among capsaicin receptor subtypes. J Biol Chem 275(4): 2756-2762 (Pubitemid 30082046)
29. Gavva NR, Klionsky L, Qu Y, Shi L, Tamir R, Edenson S, Zhang TJ, Viswanadhan VN, Toth A, Pearce LV, Vanderah TW, Porreca F, Blumberg PM, Lile J, Sun Y, Wild K, Louis JC, Treanor JJ (2004) Molecular determinants of vanilloid sensitivity in TRPV1. J Biol Chem 279(19):20283-20295 (Pubitemid 38623474)
30. Wang M, Peng J, Wang R, Zhao L, Xia Z (2010) TRPV1 Agonist capsaicin attenuates lung ischemia-reperfusion injury in rabbits. J Surg Res Epub ahead of print
31. Zhang Y, Cong X, Shi L, Xiang B, Li YM, Ding QW, Ding C, Wu LL, Yu GY (2010) Activation of transient receptor potential vanilloid subtype 1 increases secretion of the hypofunctional, transplanted submandibular gland. Am J Physiol Gastrointest Liver Physiol 299(1):G54-G62
32. Zhang LL, Yan Liu D, Ma LQ, Luo ZD, Cao TB, Zhong J, Yan ZC, Wang LJ, Zhao ZG, Zhu SJ, Schrader M, Thilo F, Zhu ZM, Tepel M (2007) Activation of transient receptor potential vanil-loid type-1 channel prevents adipogenesis and obesity. Circ Res 100(7):1063-1070 (Pubitemid 46598931)
33. Ahuja KD, Robertson IK, Geraghty DP, Ball MJ (2006) Effects of chili consumption on postprandial glucose, insulin, and energy metabolism. Am J Clin Nutr 84(1):63-69 (Pubitemid 44699172)
34. Leung FW, Go VL, Scremin OU, Obenaus A, Tuck ML, Golub MS, Eggena P, Leung JW (2007) Pilot studies to demonstrate that intestinal mucosal afferent nerves are functionally linked to visceral adipose tissue. Dig Dis Sci 52(10):2695-2702 (Pubitemid 47373889)
35. Leung FW, Golub M, Tuck M, Yip I, Leung JW, Go VL (2001) Stimulation of intestinal mucosal afferent nerves increases superior mesenteric artery and decreases mesenteric adipose tissue blood flow. Dig Dis Sci 46(6):1217-1222 (Pubitemid 32523267)