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Volumn 21, Issue 5, 2014, Pages 783-796

Conditional inactivation of Miwi2 reveals that MIWI2 is only essential for prospermatogonial development in mice

Author keywords

conditional knockout; meiosis; MIWI2; piRNAs; PIWI; transposon

Indexed keywords

MESSENGER RNA; MIWI2 PROTEIN; PIWI PROTEIN; UNCLASSIFIED DRUG; ARGONAUTE PROTEIN; PIWIL4 PROTEIN, MOUSE; SMALL INTERFERING RNA; TRANSPOSON;

EID: 84898038343     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2014.5     Document Type: Article
Times cited : (33)

References (58)
  • 1
    • 37549014207 scopus 로고    scopus 로고
    • Argonaute proteins: Key players in RNA silencing
    • Hutvagner G, Simard MJ. Argonaute proteins: key players in RNA silencing. Nat Rev. Mol Cell Biol 2008; 9: 22-32.
    • (2008) Nat Rev. Mol Cell Biol , vol.9 , pp. 22-32
    • Hutvagner, G.1    Simard, M.J.2
  • 2
    • 43549096196 scopus 로고    scopus 로고
    • The Argonaute protein family
    • Hock J, Meister G. The Argonaute protein family. Genome Biol 2008; 9: 210.
    • (2008) Genome Biol , vol.9 , pp. 210
    • Hock, J.1    Meister, G.2
  • 4
    • 33745336617 scopus 로고    scopus 로고
    • A germline-specific class of small RNAs binds mammalian Piwi proteins
    • DOI 10.1038/nature04917, PII NATURE04917
    • Girard A, Sachidanandam R, Hannon GJ, Carmell MA. A germline-specific class of small RNAs binds mammalian Piwi proteins. Nature 2006; 442: 199-202. (Pubitemid 44086566)
    • (2006) Nature , vol.442 , Issue.7099 , pp. 199-202
    • Girard, A.1    Sachidanandam, R.2    Hannon, G.J.3    Carmell, M.A.4
  • 6
    • 36749037521 scopus 로고    scopus 로고
    • The Piwi-piRNA pathway provides an adaptive defense in the transposon arms race
    • DOI 10.1126/science.1146484
    • Aravin AA, Hannon GJ, Brennecke J. The Piwi-piRNA pathway provides an adaptive defense in the transposon arms race. Science 2007; 318: 761-764. (Pubitemid 351411762)
    • (2007) Science , vol.318 , Issue.5851 , pp. 761-764
    • Aravin, A.A.1    Hannon, G.J.2    Brennecke, J.3
  • 7
    • 34248160438 scopus 로고    scopus 로고
    • Developmentally regulated piRNA clusters implicate MILI in transposon control
    • DOI 10.1126/science.1142612
    • Aravin AA, Sachidanandam R, Girard A, Fejes-Toth K, Hannon GJ. Developmentally regulated piRNA clusters implicate MILI in transposon control. Science 2007; 316: 744-747. (Pubitemid 46717682)
    • (2007) Science , vol.316 , Issue.5825 , pp. 744-747
    • Aravin, A.A.1    Sachidanandam, R.2    Girard, A.3    Fejes-Toth, K.4    Hannon, G.J.5
  • 8
    • 84867086147 scopus 로고    scopus 로고
    • Lin H. PiRNA biogenesis during adult spermatogenesis in mice is independent of the ping-pong mechanism
    • Beyret E, Liu N, Lin H. piRNA biogenesis during adult spermatogenesis in mice is independent of the ping-pong mechanism. Cell Res 2012; 22: 1429-1439.
    • (2012) Cell Res , vol.22 , pp. 1429-1439
    • Beyret, E.1    Liu, N.2
  • 9
    • 84864643089 scopus 로고    scopus 로고
    • Mili and Miwi target RNA repertoire reveals piRNA biogenesis and function of Miwi in spermiogenesis
    • Vourekas A, Zheng Q, Alexiou P, Maragkakis M, Kirino Y, Gregory BD et al. Mili and Miwi target RNA repertoire reveals piRNA biogenesis and function of Miwi in spermiogenesis. Nat Struct Mol Biol 2012; 19: 773-781.
    • (2012) Nat Struct Mol Biol , vol.19 , pp. 773-781
    • Vourekas, A.1    Zheng, Q.2    Alexiou, P.3    Maragkakis, M.4    Kirino, Y.5    Gregory, B.D.6
  • 10
    • 84864085621 scopus 로고    scopus 로고
    • The RNase III enzyme DROSHA is essential for microRNA production and spermatogenesis
    • Wu Q, Song R, Ortogero N, Zheng H, Evanoff R, Small CL et al. The RNase III enzyme DROSHA is essential for microRNA production and spermatogenesis. J Biol Chem 2012; 287: 25173-25190.
    • (2012) J Biol Chem , vol.287 , pp. 25173-25190
    • Wu, Q.1    Song, R.2    Ortogero, N.3    Zheng, H.4    Evanoff, R.5    Small, C.L.6
  • 11
    • 52049098967 scopus 로고    scopus 로고
    • A piRNA pathway primed by individual transposons is linked to de novo DNA methylation in mice
    • Aravin AA, Sachidanandam R, Bourc'his D, Schaefer C, Pezic D, Toth KF et al. A piRNA pathway primed by individual transposons is linked to de novo DNA methylation in mice. Mol Cell 2008; 31: 785-799.
    • (2008) Mol Cell , vol.31 , pp. 785-799
    • Aravin, A.A.1    Sachidanandam, R.2    Bourc'His, D.3    Schaefer, C.4    Pezic, D.5    Toth, K.F.6
  • 13
    • 65549105694 scopus 로고    scopus 로고
    • Specialized piRNA pathways act in germline and somatic tissues of the Drosophila ovary
    • Malone CD, Brennecke J, Dus M, Stark A, McCombie WR, Sachidanandam R et al. Specialized piRNA pathways act in germline and somatic tissues of the Drosophila ovary. Cell 2009; 137: 522-535.
    • (2009) Cell , vol.137 , pp. 522-535
    • Malone, C.D.1    Brennecke, J.2    Dus, M.3    Stark, A.4    McCombie, W.R.5    Sachidanandam, R.6
  • 14
    • 79952509006 scopus 로고    scopus 로고
    • PiRNA-associated germline nuage formation and spermatogenesis require MITOPLD profusogenic mitochondrial-surface lipid signaling
    • Huang H, Gao Q, Peng X, Choi SY, Sarma K, Ren H et al. piRNA-associated germline nuage formation and spermatogenesis require MITOPLD profusogenic mitochondrial-surface lipid signaling. Dev Cell 2011; 20: 376-387.
    • (2011) Dev Cell , vol.20 , pp. 376-387
    • Huang, H.1    Gao, Q.2    Peng, X.3    Choi, S.Y.4    Sarma, K.5    Ren, H.6
  • 15
    • 79952525007 scopus 로고    scopus 로고
    • MITOPLD is a mitochondrial protein essential for nuage formation and piRNA biogenesis in the mouse germline
    • Watanabe T, Chuma S, Yamamoto Y, Kuramochi-Miyagawa S, Totoki Y, Toyoda A et al. MITOPLD is a mitochondrial protein essential for nuage formation and piRNA biogenesis in the mouse germline. Dev Cell 2011; 20: 364-375.
    • (2011) Dev Cell , vol.20 , pp. 364-375
    • Watanabe, T.1    Chuma, S.2    Yamamoto, Y.3    Kuramochi-Miyagawa, S.4    Totoki, Y.5    Toyoda, A.6
  • 16
    • 77955409741 scopus 로고    scopus 로고
    • MOV10L1 is necessary for protection of spermatocytes against retrotransposons by Piwi-interacting RNAs
    • Frost RJ, Hamra FK, Richardson JA, Qi X, Bassel-Duby R, Olson EN. MOV10L1 is necessary for protection of spermatocytes against retrotransposons by Piwi-interacting RNAs. Proc Natl Acad Sci USA 2010; 107: 11847-11852.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 11847-11852
    • Frost, R.J.1    Hamra, F.K.2    Richardson, J.A.3    Qi, X.4    Bassel-Duby, R.5    Olson, E.N.6
  • 17
    • 77955406478 scopus 로고    scopus 로고
    • Mouse MOV10L1 associates with Piwi proteins and is an essential component of the Piwi-interacting RNA (piRNA) pathway
    • Zheng K, Xiol J, Reuter M, Eckardt S, Leu NA, McLaughlin KJ et al. Mouse MOV10L1 associates with Piwi proteins and is an essential component of the Piwi-interacting RNA (piRNA) pathway. Proc Natl Acad Sci USA 2010; 107: 11841-11846.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 11841-11846
    • Zheng, K.1    Xiol, J.2    Reuter, M.3    Eckardt, S.4    Leu, N.A.5    McLaughlin, K.J.6
  • 18
    • 84870722050 scopus 로고    scopus 로고
    • Blockade of pachytene piRNA biogenesis reveals a novel requirement for maintaining post-meiotic germline genome integrity
    • Zheng K, Wang PJ. Blockade of pachytene piRNA biogenesis reveals a novel requirement for maintaining post-meiotic germline genome integrity. PLoS Genet 2012; 8: e1003038.
    • (2012) PLoS Genet , vol.8
    • Zheng, K.1    Wang, P.J.2
  • 19
    • 83055180736 scopus 로고    scopus 로고
    • The endonuclease activity of Mili fuels piRNA amplification that silences LINE1 elements
    • De Fazio S, Bartonicek N, Di Giacomo M, Abreu-Goodger C, Sankar A, Funaya C et al. The endonuclease activity of Mili fuels piRNA amplification that silences LINE1 elements. Nature 2011; 480: 259-263.
    • (2011) Nature , vol.480 , pp. 259-263
    • De Fazio, S.1    Bartonicek, N.2    Di Giacomo, M.3    Abreu-Goodger, C.4    Sankar, A.5    Funaya, C.6
  • 20
    • 67349141725 scopus 로고    scopus 로고
    • Loss of the Mili-interacting Tudor domain-containing protein-1 activates transposons and alters the Mili-associated small RNA profile
    • Reuter M, Chuma S, Tanaka T, Franz T, Stark A, Pillai RS. Loss of the Mili-interacting Tudor domain-containing protein-1 activates transposons and alters the Mili-associated small RNA profile. Nat Struct Mol Biol 2009; 16: 639-646.
    • (2009) Nat Struct Mol Biol , vol.16 , pp. 639-646
    • Reuter, M.1    Chuma, S.2    Tanaka, T.3    Franz, T.4    Stark, A.5    Pillai, R.S.6
  • 21
    • 71649101009 scopus 로고    scopus 로고
    • The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline
    • Shoji M, Tanaka T, Hosokawa M, Reuter M, Stark A, Kato Y et al. The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline. Dev Cell 2009; 17: 775-787.
    • (2009) Dev Cell , vol.17 , pp. 775-787
    • Shoji, M.1    Tanaka, T.2    Hosokawa, M.3    Reuter, M.4    Stark, A.5    Kato, Y.6
  • 22
    • 68549128834 scopus 로고    scopus 로고
    • PiRNAs mediate posttranscriptional retroelement silencing and localization to pi-bodies in the Drosophila germline
    • Lim AK, Tao L, Kai T. piRNAs mediate posttranscriptional retroelement silencing and localization to pi-bodies in the Drosophila germline. J Cell Biol 2009; 186: 333-342.
    • (2009) J Cell Biol , vol.186 , pp. 333-342
    • Lim, A.K.1    Tao, L.2    Kai, T.3
  • 23
    • 67249090774 scopus 로고    scopus 로고
    • Peculiarities of piRNA-mediated post-transcriptional silencing of Stellate repeats in testes of Drosophila melanogaster
    • Kotelnikov RN, Klenov MS, Rozovsky YM, Olenina LV, Kibanov MV, Gvozdev VA. Peculiarities of piRNA-mediated post-transcriptional silencing of Stellate repeats in testes of Drosophila melanogaster. Nucleic Acids Res 2009; 37: 3254-3263.
    • (2009) Nucleic Acids Res , vol.37 , pp. 3254-3263
    • Kotelnikov, R.N.1    Klenov, M.S.2    Rozovsky, Y.M.3    Olenina, L.V.4    Kibanov, M.V.5    Gvozdev, V.A.6
  • 25
    • 78049387387 scopus 로고    scopus 로고
    • Maternal mRNA deadenylation and decay by the piRNA pathway in the early Drosophila embryo
    • Rouget C, Papin C, Boureux A, Meunier AC, Franco B, Robine N et al. Maternal mRNA deadenylation and decay by the piRNA pathway in the early Drosophila embryo. Nature 2010; 467: 1128-1132.
    • (2010) Nature , vol.467 , pp. 1128-1132
    • Rouget, C.1    Papin, C.2    Boureux, A.3    Meunier, A.C.4    Franco, B.5    Robine, N.6
  • 26
    • 77957775830 scopus 로고    scopus 로고
    • Somatic piRNA biogenesis
    • Zamore PD. Somatic piRNA biogenesis. EMBO J 2010; 29: 3219-3221.
    • (2010) EMBO J , vol.29 , pp. 3219-3221
    • Zamore, P.D.1
  • 27
    • 84866854050 scopus 로고    scopus 로고
    • A role for Fkbp6 and the chaperone machinery in piRNA amplification and transposon silencing
    • Xiol J, Cora E, Koglgruber R, Chuma S, Subramanian S, Hosokawa M et al. A role for Fkbp6 and the chaperone machinery in piRNA amplification and transposon silencing. Mol Cell 2012; 47: 970-979.
    • (2012) Mol Cell , vol.47 , pp. 970-979
    • Xiol, J.1    Cora, E.2    Koglgruber, R.3    Chuma, S.4    Subramanian, S.5    Hosokawa, M.6
  • 31
    • 70350238350 scopus 로고    scopus 로고
    • The biogenesis and function of PIWI proteins and piRNAs: Progress and prospect
    • Thomson T, Lin H. The biogenesis and function of PIWI proteins and piRNAs: progress and prospect. Ann Rev CellDev Biol 2009; 25: 355-376.
    • (2009) Ann Rev CellDev Biol , vol.25 , pp. 355-376
    • Thomson, T.1    Lin, H.2
  • 32
    • 65049088735 scopus 로고    scopus 로고
    • Mili interacts with tudor domain-containing protein 1 in regulating spermatogenesis
    • Wang J, Saxe JP, Tanaka T, Chuma S, Lin H. Mili interacts with tudor domain-containing protein 1 in regulating spermatogenesis. Curr Biol 2009; 19: 640-644.
    • (2009) Curr Biol , vol.19 , pp. 640-644
    • Wang, J.1    Saxe, J.P.2    Tanaka, T.3    Chuma, S.4    Lin, H.5
  • 33
    • 84878205591 scopus 로고    scopus 로고
    • Multiple epigenetic mechanisms and the piRNA pathway enforce LINE1 silencing during adult spermatogenesis
    • Di Giacomo M, Comazzetto S, Saini H, De Fazio S, Carrieri C, Morgan M et al. Multiple epigenetic mechanisms and the piRNA pathway enforce LINE1 silencing during adult spermatogenesis. Mol Cell 2013; 50: 601-608.
    • (2013) Mol Cell , vol.50 , pp. 601-608
    • Di Giacomo, M.1    Comazzetto, S.2    Saini, H.3    De Fazio, S.4    Carrieri, C.5    Morgan, M.6
  • 34
    • 84876070120 scopus 로고    scopus 로고
    • An ancient transcription factor initiates the burst of piRNA production during early meiosis in mouse testes
    • Li XZ, Roy CK, Dong X, Bolcun-Filas E, Wang J, Han BW et al. An ancient transcription factor initiates the burst of piRNA production during early meiosis in mouse testes. Mol Cell 2013; 50: 67-81.
    • (2013) Mol Cell , vol.50 , pp. 67-81
    • Li, X.Z.1    Roy, C.K.2    Dong, X.3    Bolcun-Filas, E.4    Wang, J.5    Han, B.W.6
  • 35
    • 83055193640 scopus 로고    scopus 로고
    • Miwi catalysis is required for piRNA amplification-independent LINE1 transposon silencing
    • Reuter M, Berninger P, Chuma S, Shah H, Hosokawa M, Funaya C et al. Miwi catalysis is required for piRNA amplification-independent LINE1 transposon silencing. Nature 2011; 480: 264-267.
    • (2011) Nature , vol.480 , pp. 264-267
    • Reuter, M.1    Berninger, P.2    Chuma, S.3    Shah, H.4    Hosokawa, M.5    Funaya, C.6
  • 36
    • 84855927549 scopus 로고    scopus 로고
    • Chuma S. PiRNAs and their involvement in male germline development in mice
    • Pillai RS, Chuma S. piRNAs and their involvement in male germline development in mice. Dev Growth Differ 2012; 54: 78-92.
    • (2012) Dev Growth Differ , vol.54 , pp. 78-92
    • Pillai, R.S.1
  • 37
    • 84864015827 scopus 로고    scopus 로고
    • Male germline control of transposable elements
    • Bao J, Yan W. Male germline control of transposable elements. Biol Reprod 2012; 865: 1-14.
    • (2012) Biol Reprod , vol.865 , pp. 1-14
    • Bao, J.1    Yan, W.2
  • 38
    • 33646814901 scopus 로고    scopus 로고
    • Human LINE-1 retrotransposon induces DNA damage and apoptosis in cancer cells
    • Belgnaoui SM, Gosden RG, Semmes OJ, Haoudi A. Human LINE-1 retrotransposon induces DNA damage and apoptosis in cancer cells. Cancer Cell Int 2006; 6: 13.
    • (2006) Cancer Cell Int , vol.6 , pp. 13
    • Belgnaoui, S.M.1    Gosden, R.G.2    Semmes, O.J.3    Haoudi, A.4
  • 39
    • 34347351997 scopus 로고    scopus 로고
    • Generation of a germ cell-specific mouse transgenic Cre line, Vasa-Cre
    • DOI 10.1002/dvg.20310
    • Gallardo T, Shirley L, John GB, Castrillon DH. Generation of a germ cell-specific mouse transgenic Cre line, Vasa-Cre. Genesis 2007; 45: 413-417. (Pubitemid 47015328)
    • (2007) Genesis , vol.45 , Issue.6 , pp. 413-417
    • Gallardo, T.1    Shirley, L.2    John, G.B.3    Castrillon, D.H.4
  • 40
    • 59649109441 scopus 로고    scopus 로고
    • Cre recombinase activity specific to postnatal, premeiotic male germ cells in transgenic mice
    • Sadate-Ngatchou PI, Payne CJ, Dearth AT, Braun RE. Cre recombinase activity specific to postnatal, premeiotic male germ cells in transgenic mice. Genesis 2008; 46: 738-742.
    • (2008) Genesis , vol.46 , pp. 738-742
    • Sadate-Ngatchou, P.I.1    Payne, C.J.2    Dearth, A.T.3    Braun, R.E.4
  • 41
    • 84898038362 scopus 로고    scopus 로고
    • Incomplete cre-mediated excision leads to phenotypic differences between Stra8-iCre; Mov10l1 and Stra8-iCre; Mov10l1 mice
    • Bao J, Ma HY, Schuster A, Lin YM, Yan W. Incomplete cre-mediated excision leads to phenotypic differences between Stra8-iCre; Mov10l1 and Stra8-iCre; Mov10l1 mice. Genesis 2013; 1-10.
    • (2013) Genesis , pp. 1-10
    • Bao, J.1    Ma, H.Y.2    Schuster, A.3    Lin, Y.M.4    Yan, W.5
  • 43
    • 70350539626 scopus 로고    scopus 로고
    • GammaH2AX marks the main events of the spermatogenic process
    • Blanco-Rodriguez J. GammaH2AX marks the main events of the spermatogenic process. Micros Res Tech 2009; 72: 823-832.
    • (2009) Micros Res Tech , vol.72 , pp. 823-832
    • Blanco-Rodriguez, J.1
  • 44
    • 0028223562 scopus 로고
    • Developmentally regulated expression of a mouse germ cell nuclear antigen examined from embryonic day 11 to adult in male and female mice
    • DOI 10.1006/dbio.1994.1152
    • Enders GC, May JJ 2nd. Developmentally regulated expression of a mouse germ cell nuclear antigen examined from embryonic day 11 to adult in male and female mice. Dev Biol 1994; 163: 331-340. (Pubitemid 24221618)
    • (1994) Developmental Biology , vol.163 , Issue.2 , pp. 331-340
    • Enders, G.C.1    May II, J.J.2
  • 46
    • 79956052873 scopus 로고    scopus 로고
    • Role for piRNAs and noncoding RNA in de novo DNA methylation of the imprinted mouse Rasgrf1 locus
    • Watanabe T, Tomizawa S, Mitsuya K, Totoki Y, Yamamoto Y, Kuramochi-Miyagawa S et al. Role for piRNAs and noncoding RNA in de novo DNA methylation of the imprinted mouse Rasgrf1 locus. Science 2011; 332: 848-852.
    • (2011) Science , vol.332 , pp. 848-852
    • Watanabe, T.1    Tomizawa, S.2    Mitsuya, K.3    Totoki, Y.4    Yamamoto, Y.5    Kuramochi-Miyagawa, S.6
  • 47
    • 27844440989 scopus 로고    scopus 로고
    • A histone H3 methyltransferase controls epigenetic events required for meiotic prophase
    • DOI 10.1038/nature04112, PII N04112
    • Hayashi K, Yoshida K, Matsui Y. A histone H3 methyltransferase controls epigenetic events required for meiotic prophase. Nature 2005; 438: 374-378. (Pubitemid 41643955)
    • (2005) Nature , vol.438 , Issue.7066 , pp. 374-378
    • Hayashi, K.1    Yoshida, K.2    Matsui, Y.3
  • 48
    • 34547221416 scopus 로고    scopus 로고
    • Functional dynamics of H3K9 methylation during meiotic prophase progression
    • DOI 10.1038/sj.emboj.7601767, PII 7601767
    • Tachibana M, Nozaki M, Takeda N, Shinkai Y. Functional dynamics of H3K9 methylation during meiotic prophase progression. EMBO J 2007; 26: 3346-3359. (Pubitemid 47123532)
    • (2007) EMBO Journal , vol.26 , Issue.14 , pp. 3346-3359
    • Tachibana, M.1    Nozaki, M.2    Takeda, N.3    Shinkai, Y.4
  • 49
    • 80355128032 scopus 로고    scopus 로고
    • Flow cytometryurification of mouse meiotic cells
    • pii 2602
    • Getun IV, Torres B, Bois PR. Flow cytometryurification of mouse meiotic cells. J Vis Exp 2011; 50: pii 2602.
    • (2011) J Vis Exp , vol.50
    • Getun, I.V.1    Torres, B.2    Bois, P.R.3
  • 50
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • Huang da W, Sherman BT, Lempicki RA. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 2009; 4: 44-57.
    • (2009) Nat Protoc , vol.4 , pp. 44-57
    • Huang Da, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 52
    • 84857637929 scopus 로고    scopus 로고
    • STK31(TDRD8) is dynamically regulated throughout mouse spermatogenesis and interacts with MIWI protein
    • Bao J, Wang L, Lei J, Hu Y, Liu Y, Shen H et al. STK31(TDRD8) is dynamically regulated throughout mouse spermatogenesis and interacts with MIWI protein. Histochem Cell Biol 2012; 137: 377-389.
    • (2012) Histochem Cell Biol , vol.137 , pp. 377-389
    • Bao, J.1    Wang, L.2    Lei, J.3    Hu, Y.4    Liu, Y.5    Shen, H.6
  • 53
    • 79651474455 scopus 로고    scopus 로고
    • RANBP17 is localized to the XY body of spermatocytes and interacts with SPEM1 on the manchette of elongating spermatids
    • Bao J, Wu Q, Song R, Jie Z, Zheng H, Xu C et al. RANBP17 is localized to the XY body of spermatocytes and interacts with SPEM1 on the manchette of elongating spermatids. Mol Cell Endocrinol 2011; 333: 134-142.
    • (2011) Mol Cell Endocrinol , vol.333 , pp. 134-142
    • Bao, J.1    Wu, Q.2    Song, R.3    Jie, Z.4    Zheng, H.5    Xu, C.6
  • 54
    • 48549092573 scopus 로고    scopus 로고
    • Mouse maelstrom, a component of nuage, is essential for spermatogenesis and transposon repression in meiosis
    • Soper SF, van der Heijden GW, Hardiman TC, Goodheart M, Martin SL, de Boer P et al. Mouse maelstrom, a component of nuage, is essential for spermatogenesis and transposon repression in meiosis. Dev Cell 2008; 15: 285-297.
    • (2008) Dev Cell , vol.15 , pp. 285-297
    • Soper, S.F.1    Van Der Heijden, G.W.2    Hardiman, T.C.3    Goodheart, M.4    Martin, S.L.5    De Boer, P.6
  • 56
    • 84862680867 scopus 로고    scopus 로고
    • MicroRNA-449 and microRNA-34b/c function redundantly in murine testes by targeting E2F transcription factor-retinoblastoma protein (E2F-pRb) pathway
    • Bao J, Li D, Wang L, Wu J, Hu Y, Wang Z et al. MicroRNA-449 and microRNA-34b/c function redundantly in murine testes by targeting E2F transcription factor-retinoblastoma protein (E2F-pRb) pathway. J Biol Chem 2012; 287: 21686-21698.
    • (2012) J Biol Chem , vol.287 , pp. 21686-21698
    • Bao, J.1    Li, D.2    Wang, L.3    Wu, J.4    Hu, Y.5    Wang, Z.6
  • 57
    • 84866878555 scopus 로고    scopus 로고
    • Epigenetic transgenerational inheritance of somatic transcriptomes and epigenetic control regions
    • Skinner MK, Mohan M, Haque MM, Zhang B, Savenkova MI. Epigenetic transgenerational inheritance of somatic transcriptomes and epigenetic control regions. Genome Biol 2012; 13: R91.
    • (2012) Genome Biol , vol.13
    • Skinner, M.K.1    Mohan, M.2    Haque, M.M.3    Zhang, B.4    Savenkova, M.I.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.