Pentamethoxyflavanone regulates macrophage polarization and ameliorates sepsis in mice

Biochemical Pharmacology

Volumn 89, Issue 1, 2014, Pages 109-118

  Feng, Lili ^a   Song, Pingping ^b   Zhou, Hang ^a   Wu, Xudong ^a   Li, Ang ^a   Ma, Yuxiang ^a   Zhang, Xiong ^a   Liu, Hailiang ^a   Xu, Ge ^a   Zhou, Yang ^a   Wu, Xuefeng ^a   Shen, Yan ^a   Sun, Yang ^a   Xu, Qiang ^a  

^a NANJING UNIVERSITY   (China)

^b INSTITUTE OF BOTANY   (China)

Author keywords

5,7,3 ,4 ,5 Pentamethoxyflavanone (PMFA); Anti inflammation; Macrophage polarization; Sepsis; STAT1 STAT6 signals

Indexed keywords

5,7,30,40,50 PENTAMETHOXYFLAVANONE; FLAVONE DERIVATIVE; INTERLEUKIN 1BETA; INTERLEUKIN 6; STAT1 PROTEIN; STAT6 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; B LYMPHOCYTE ACTIVATION; BONE MARROW CELL; BONE MARROW DERIVED MACROPHAGE; CELL INFILTRATION; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; FEMALE; IN VITRO STUDY; INFECTION PREVENTION; LUNG LAVAGE; M1 MACROPHAGE; M2 MACROPHAGE; M2 MACROPHAGE RELATED MOLECULE; MACROPHAGE; MACROPHAGE FUNCTION; MACROPHAGE PHENOTYPE SHIFT; MOUSE; NONHUMAN; PHENOTYPE; POLARIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEPSIS; SIGNAL TRANSDUCTION; SURVIVAL RATE; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TISSUE INJURY; UPREGULATION;

5,7,3′,4′,5′-PENTAMETHOXYFLAVANONE (PMFA); ANTI-INFLAMMATION; MACROPHAGE POLARIZATION; SEPSIS; STAT1/STAT6 SIGNALS;

ANIMALS; BLOTTING, WESTERN; BRONCHOALVEOLAR LAVAGE FLUID; CELL LINE; FEMALE; FLAVANONES; FLOW CYTOMETRY; MACROPHAGES; MICE; MICE, INBRED C57BL; POLYMERASE CHAIN REACTION; SEPSIS; STAT1 TRANSCRIPTION FACTOR; STAT6 TRANSCRIPTION FACTOR;

EID: 84898016603     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2014.02.016     Document Type: Article

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