The role of intestinal microbiota in development of irinotecan toxicity and in toxicity reduction through dietary fibres in rats

PLoS ONE

Volumn 9, Issue 1, 2014, Pages

  Lin, Xiaoxi B ^a   Farhangfar, Arazm ^a   Valcheva, Rosica ^a   Sawyer, Michael B ^a   Dieleman, Levinus ^a   Schieber, Andreas ^a,b   Gänzle, Michael G ^a   Baracos, Vickie ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b UNIVERSITY OF BONN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GLUCURONIDASE; BUTYRIC ACID; CARBOHYDRATE; DRUG METABOLITE; FIRTECAN; FLUOROURACIL; INTERLEUKIN 1BETA; IRINOTECAN; MONOCARBOXYLATE TRANSPORTER 1;

ANIMAL EXPERIMENT; ANIMAL HEALTH; ANIMAL MODEL; ARTICLE; BACTERIAL GENE; BACTERIAL OVERGROWTH; BACTERIAL TRANSLOCATION; BODY WEIGHT; BUTYRYL COA GENE; CECUM; CITROBACTER FREUNDII; COLON CARCINOMA; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; DIET SUPPLEMENTATION; DIETARY FIBER; ENTEROBACTERIACEAE; ENTEROCOCCUS; FEMALE; FOOD INTAKE; GENE EXPRESSION; HOST; HOST PATHOGEN INTERACTION; INTESTINE FLORA; KLEBSIELLA OXYTOCA; MESENTERY LYMPH NODE; MICROBIAL COMMUNITY; MULTIPLE CYCLE TREATMENT; NONHUMAN; POPULATION ABUNDANCE; RAT; STAPHYLOCOCCUS; TOXICITY;

ANIMALS; BUTYRATES; CAMPTOTHECIN; CECUM; DIETARY FIBER; FATTY ACIDS; FEMALE; GLUCURONIDASE; HUMANS; INTESTINES; MICROBIOTA; RATS;

EID: 84898016390     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0083644     Document Type: Article

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