Polymersome-mediated delivery of combination anticancer therapy to head and neck cancer cells: 2D and 3D in vitro evaluation

Molecular Pharmaceutics

Volumn 11, Issue 4, 2014, Pages 1176-1188

  Colley, Helen E ^a   Hearnden, Vanessa ^a,b   Avila Olias, Milagros ^a,c   Cecchin, Denis ^a,c,d   Canton, Irene ^a   Madsen, Jeppe ^a   Macneil, Sheila ^b   Warren, Nicholas ^a   Hu, Ke ^e   McKeating, Jane A ^e   Armes, Steven P ^a   Murdoch, Craig ^a   Thornhill, Martin H ^a   Battaglia, Giuseppe ^a,c,d  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b Department of Biomedical Science University of Sheffield ^*  (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d MEDICAL RESEARCH COUNCIL   (United Kingdom)

^e UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

doxorubicin; drug delivery; head and neck cancer; multicellular tumor spheroid; paclitaxel; polymersomes; scavenger receptors

Indexed keywords

COPOLYMER; DOXORUBICIN; PACLITAXEL; POLY 2 (DIISOPROPYLAMINO)ETHYL METHACRYLATE; POLY 2 (METHACRYLOYLOXY)ETHYL PHOSPHORYLCHOLINE; POLYMERSOME; SCAVENGER RECEPTOR B; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; DIMYRISTOYLPHOSPHATIDYLCHOLINE; POLY(2-(DIISOPROPYLAMINO)ETHYL METHACRYLATE); POLYMETHACRYLIC ACID DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CELL CULTURE; CELL DAMAGE; CELL VIABILITY; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; ENCAPSULATION; HEAD AND NECK SQUAMOUS CELL CARCINOMA; HUMAN; HUMAN CELL; IN VITRO STUDY; INTERNALIZATION; MONOLAYER CULTURE; MULTICELLULAR SPHEROID; PH; PRIORITY JOURNAL; CARCINOMA, SQUAMOUS CELL; HEAD AND NECK NEOPLASMS; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; DIMYRISTOYLPHOSPHATIDYLCHOLINE; DOXORUBICIN; DRUG DELIVERY SYSTEMS; HEAD AND NECK NEOPLASMS; HUMANS; HYDROGEN-ION CONCENTRATION; PACLITAXEL; POLYMETHACRYLIC ACIDS;

EID: 84898015500     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp400610b     Document Type: Article

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