Diffusion studies of nanometer polymersomes across tissue engineered human oral mucosa

Pharmaceutical Research

Volumn 26, Issue 7, 2009, Pages 1718-1728

  Hearnden, Vanessa ^a   Lomas, Hannah ^a   MacNeil, Sheila ^a   Thornhill, Martin ^a   Murdoch, Craig ^a   Lewis, Andrew ^b   Madsen, Jeppe ^a   Blanazs, Adam ^a   Armes, Steve ^a   Battaglia, Giuseppe ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b BIOCOMPATIBLES UK LTD   (United Kingdom)

Author keywords

Confocal laser scanning microscopy; Diffusion; Epithelium; Oral mucosa; Polymersome

Indexed keywords

2 (METHACRYLOYLOXY)ETHYLPHOSPHORYLCHOLINE POLY[2 (DIISOPROPYLAMINO)ETHYLMETHACRYLATE]; COPOLYMER; NANOMATERIAL; POLY(ETHYLENE OXIDE) POLY[2 (DIISOPROPYLAMINO)ETHYLMETHACRYLATE]; RHODAMINE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DERMIS; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; HUMAN; HUMAN CELL; MOUTH MUCOSA; PARTICLE SIZE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; TISSUE ENGINEERING;

BIOLOGICAL TRANSPORT; CELLS, CULTURED; DIFFUSION; DRUG CARRIERS; FIBROBLASTS; HUMANS; KERATINOCYTES; METHACRYLATES; MICROSCOPY, CONFOCAL; MOUTH MUCOSA; PHOSPHORYLCHOLINE; POLYETHYLENE GLYCOLS; POLYMETHACRYLIC ACIDS; TISSUE ENGINEERING;

EID: 67349092430     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-009-9882-6     Document Type: Article

References (48)

1. S MacNeil 2007 Progress and opportunities for tissue-engineered skin Nature 445 874 880 doi:10.1038/nature05664
2. K Moharamzadeh IM Brook R Van Noort AM Scutt MH Thornhill 2007 Tissue-engineered oral mucosa: a review of the scientific literature J Dent Res 86 115 124 doi:10.1177/154405910708600203
3. G Schmalz 2002 Materials science: biological aspects J Dent Res 81 660 663 doi:10.1177/154405910208101001
4. G Schmalz U Schuster A Koch H Scheweikl 2002 Cytotoxicity of low pH dentin-bonding agents in a dentin barrier test in vitro J Endod 28 188 192 doi:10.1097/00004770-200203000-00011
5. KH Chakrabarty RA Dawson P Harris C Layton M Babu L Gould J Phillips I Leigh C Green E Freedlander S Mac Neil 1999 Development of autologous human dermal-epidermal composites based on sterilized human allodermis for clinical use Br J Dermatol 141 811 823 doi:10.1046/j.1365-2133.1999.03153.x
6. L Selvaratnam AT Cruchley H Navsaria PW Wertz EP Hagi-Pavli IM Leigh CA Squier DM Williams 2001 Permeability barrier properties of oral keratinocyte cultures: a model of intact human oral mucosa Oral Dis 7 252 258 doi:10.1034/j.1601-0825.2001.70409.x
7. S Bhargava CR Chapple AJ Bullock C Layton S MacNeil 2004 Tissue-engineered buccal mucosa for substitution urethroplasty BJU Int 93 807 811 doi:10.1111/j.1464-410X.2003.04723.x
8. S Bhargava JM Patterson RD Inman S MacNeil CR Chapple 2008 Tissue-engineered buccal mucosa urethroplasty-clinical outcomes Eur Urol 53 1263 1271 doi:10.1016/j.eururo.2008.01.061
9. T Smart H Lomas M Massignani MV Flores-Merino LR Perez G Battaglia 2008 Block copolymer nanostructures Nanotoday 3 1 9
10. J Du Y Tang AL Lewis SP Armes 2005 pH-sensitive vesicles based on a biocompatible zwitterionic diblock copolymer J Am Chem Soc 127 17982 17983 doi:10.1021/ja056514l
11. Madsen J. PhD thesis, University of Sheffield; 2009
12. BM Discher Y Won DS Ege JCM Lee FS Bates DE Discher DA Hammer 1999 Polymersomes: tough vesicles made from diblock copolymers Science 284 1143 1146 doi:10.1126/science.284.5417.1143
13. DE Discher A Eisenberg 2002 Polymer vesicles Science 297 967 973 doi:10.1126/science.1074972
14. AD Bangham 1961 A correlation between surface charge and coagulant action of phospholipids Nature 192 1197 1198 doi:10.1038/1921197a0
15. Lasic DD, Papahadjopoulos D. Medical applications of liposomes. Amsterdam: Elsevier; 1998.
16. PJ Photos L Bacakova B Discher FS Bates DE Discher 2003 Polymer vesicles in vivo: correlations with PEG molecular weight J Control Release 90 323 334 doi:10.1016/S0168-3659(03)00201-3
17. DD Lasic 1994 Sterically stabilized vesicles Angew Chem Int Ed 33 1685 1698 doi:10.1002/anie.199416851
18. DD Lasic 1997 Recent developments in medical applications of liposomes: sterically stabilized liposomes in cancer therapy and gene delivery in vivo J Control Release 48 203 222 doi:10.1016/S0168-3659(97)00045-X
19. R Duncan 2003 The dawning era of polymer therapeutics Nat Rev Drug Discov 2 347 360 doi:10.1038/nrd1088
20. DE Discher V Ortiz G Srinivas ML Klein Y Kim D Christian S Cai P Photos F Ahmed 2007 Emerging applications of polymersomes in delivery: from molecular dynamics to shrinkage of tumors Prog Polym Sci 32 838 857 doi:10.1016/j. progpolymsci.2007.05.011
21. G Battaglia A Ryan 2005 Bilayers and interdigitation in block copolymer vesicles J Am Chem Soc 127 8757 8764 doi:10.1021/ja050742y
22. G Battaglia AJ Ryan S Tomas 2006 Polymeric vesicle permeability: a facile chemical assay Langmuir 22 4910 4913 doi:10.1021/la060354p
23. H Aranda-Espinoza H Bermudez FS Bates DE Discher 2001 Electromechanical limits of polymersomes Phys Rev Lett 87 208301 doi:10.1103/PhysRevLett.87.208301
24. H Lomas I Canton S MacNeil J Du SPA Armes AJ Ryan AL Lewis G Battaglia 2007 Biomimetic pH sensitive polymersomes for efficient DNA encapsulation and delivery Adv Mater 19 4238 4243 doi:10.1002/adma.200700941
25. H Lomas M Massignani KA Abdullah I Canton C Lo Presti S MacNeil J Du A Blanazs J Madsen SP Armes AL Lewis G Battaglia 2008 Non-cytotoxic polymer vesicles for rapid and efficient intracellular delivery Faraday Discuss 139 143 doi:10.1039/b717431d
26. S Rameez H Alosta AF Palmer 2008 Biocompatible and biodegradable polymersome encapsulated hemoglobin: a potential oxygen carrier Bioconjugate Chem 19 1025 1032 doi:10.1021/bc700465v
27. DR Arifin AF Palmer 2005 Polymersome encapsulated hemoglobin: a novel type of oxygen carrier Biomacromolecules 6 2172 2181 doi:10.1021/bm0501454
28. PP Ghoroghchian PR Frail K Susumu D Blessington AK Brannan FS Bates B Chance DA Hammer MJ Therien 2005 Near-infrared-emissive polymersomes: self-assembled soft matter for in vivo optical imaging PNAS 102 2922 2927 doi:10.1073/pnas.0409394102
29. JJ Lin PP Ghoroghchian Y Zhang DA Hammer 2006 Adhesion of antibody-functionalized polymersomes Langmuir 22 3975 3979 doi:10.1021/la052445c
30. K Matyjaszewski J Spanswick 2005 Controlled/living radical polymerization Mater Today 8 26 33 doi:10.1016/S1369-7021(05)00745-5
31. S Cerritelli D Velluto JA Hubbell 2007 PEG-SS-PPS: reduction-sensitive disulfide block copolymer vesicles for intracellular drug delivery Biomacromolecules 8 1966 1972 doi:10.1021/bm070085x
32. F Meng GHM Engbers J Feijen 2005 Biodegradable polymersomes as a basis for artificial cells: encapsulation, release and targeting J Control Release 101 187 198 doi:10.1016/j.jconrel.2004.09.026
33. N Ben-Haim P Broz S Marsch W Meier P Hunziker 2008 Cell-specific integration of artificial organelles based on functionalized polymer vesicles Nano Letters 8 1368 1373 doi:10.1021/nl080105g
34. S Sood SJ Shiff CS Yang X Chen 2005 Selection of topically applied non-steroidal anti-inflammatory drugs for oral cancer chemoprevention Oral Oncol 41 562 567 doi:10.1016/j.oraloncology.2005.01.003
35. H Zhang J Zhang JB Streisand 2002 Oral mucosal drug delivery: clinical pharmacokinetics and therapeutic applications Clin Pharmacokinet 41 661 680 doi:10.2165/00003088-200241090-00003
36. 4 J Mater Chem 12 890 896 doi:10.1039/b200348c
37. JG Rheinwald H Green 1975 Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinizing colonies from single cells Cell 6 331 343 doi:10.1016/S0092-8674(75)80001-8
38. Nanci A. Ten Cate's oral histology-development, structure and function. St. Louis: Mosby; 2003.
39. K Schenke-Layland I Riemann O Damour UA Stock K König 2006 Two-photon microscopes and in vivo multiphoton tomographs-powerful diagnostic tools for tissue engineering and drug delivery Adv Drug Deliv Rev 58 878 896 doi:10.1016/j.addr.2006.07.004
40. IC Mackenzie NE Fusenig 1983 Regeneration of organized epithelial structure J Invest Dermatol 81 189s 194s doi:10.1111/1523-1747.ep12541093
41. DE Costea LL Loro EAO Dimba OK Vintermyr AC Johannessen 2003 Crucial effects of fibroblasts and keratinocyte growth factor on morphogenesis of reconstituted human oral epithelium J Invest Dermatol 121 1479 1486 doi:10.1111/j.1523-1747.2003.12616.x
42. NA Alcantar ES Aydil JN Israelachvili 2000 Polyethylene glycol-coated biocompatible surfaces J Biomed Mater Res 51 343 351
43. Massignani M, Blanazs A, Madsen J, Armes SP, Lewis AL, Battaglia G. Engineering polymeric nanovectors for effective and rapid cellular delivery. In preparation (2008).
44. G Campisi G Giandalia V De Caro C Di Liberto P Aricò LI Giannola 2004 A new delivery system of clobetasol-17-propionate (lipid-loaded microspheres) compared with a conventional formulation (lipophilic ointment in a hydrophilic phase) in topical treatment of atrophic/erosive oral lichen planus. A Phase IV, randomized, observer-blinded, parallel group clinical trial Br J Dermatol 150 984 990 doi:10.1111/j.1365-2133.2004.05943.x
45. J Blanchette N Kavimandan NA Peppas 2004 Principles of transmucosal delivery of therapeutic agents Biomed Pharmacother 58 142 151 doi:10.1016/j.biopha.2004.01.006
46. RH Guy 1996 Current status and future prospects of transdermal drug delivery Pharm Res 13 1765 1769 doi:10.1023/A:1016060403438
47. M Shimono F Clementi 1976 Intercellular junctions of oral epithelium. I. Studies with freeze-fracture and tracing methods of normal rat keratinized oral epithelium J Ultrastruct Res 56 121 136 doi:10.1016/S0022-5320(76)80145-1
48. G Cevc D Gebauer 2003 Hydration-driven transport of deformable lipid vesicles through fine pores and the skin barrier Biophys J 84 1010 1024 doi:10.1016/S0006-3495(03)74917-0