TGF-β favors bone marrow-derived dendritic cells to acquire tolerogenic properties

Immunological Investigations

Volumn 43, Issue 4, 2014, Pages 360-369

  Song, Sha Sha ^a   Yuan, Ping Fan ^a   Chen, Jing Yu ^a   Fu, Jing Jing ^a   Wu, Hua Xun ^a   Lu, J T ^a   Wei, W ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

CD45RB; Dendritic cells; Immune tolerance; Indoleamine 2, 3 dioxygenase; Transforming growth factor

Indexed keywords

CD40 ANTIGEN; CD45RB ANTIGEN; CD83 ANTIGEN; CD86 ANTIGEN; INDOLEAMINE 2,3 DIOXYGENASE; INTERLEUKIN 10; INTERLEUKIN 12; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; TRANSFORMING GROWTH FACTOR BETA; MEMBRANE ANTIGEN;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; BONE MARROW CELL; CELL DIFFERENTIATION; CONTROLLED STUDY; CYTOKINE RELEASE; ENDOCYTOSIS; IMMUNOGENICITY; IMMUNOLOGICAL TOLERANCE; MALE; MIXED LYMPHOCYTE REACTION; MOUSE; MYELOID DENDRITIC CELL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SUPERNATANT; T LYMPHOCYTE ACTIVATION; ANIMAL; BIOSYNTHESIS; DENDRITIC CELL; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; IMMUNOPHENOTYPING; LYMPHOCYTE ACTIVATION; METABOLISM; T LYMPHOCYTE;

ANIMALS; ANTIGENS, SURFACE; DENDRITIC CELLS; ENDOCYTOSIS; GENE EXPRESSION REGULATION; IMMUNE TOLERANCE; IMMUNOPHENOTYPING; INTERLEUKIN-10; INTERLEUKIN-12; LYMPHOCYTE ACTIVATION; MALE; MICE; T-LYMPHOCYTES; TRANSFORMING GROWTH FACTOR BETA;

EID: 84898012300     PISSN: 08820139     EISSN: 15324311     Source Type: Journal    
DOI: 10.3109/08820139.2013.879172     Document Type: Article

References (30)

1. Bonnefoy F, Couturier M, Clauzon A, et al. (2011). TGF-b-exposed plasmacytoid dendritic cells participate in Th17 commitment. J Immunol, 186, 6157-64.
2. Chen L, Qiu M, He W, et al. (2012). Functional study of immature dendritic cells co-transfected with IL-10 and TGF-beta 1 genes in vitro. Mol Biol Rep, 39, 6633-9.
3. + regulatory T cells. J Cell Mol Med, 12, 690-700. (Pubitemid 351555146)
4. den Hartog G, van Altena C, Savelkoul HF, van Neerven RJ. (2013). The mucocal factors retinoic acid and TGF-b1 induce phenotypically and functional distinct dendritic cell types. Int Arch Allergy Immunol, 162, 225-36.
5. Fogel-Petrovic M, Long JA, Misso NL, et al. (2007). Physiological concentrations of transforming growth factor beta1 selectively inhibit human dendritic cell function. Int Immunopharmacol, 7, 1924-33. (Pubitemid 350138512)
6. Griffiths KL, O'Neill HC. (2008). Dendritic cells as immune regulators: the mouse model. J Cell Mol Med, 12, 1909-14.
7. Harden JL, Egilmez NK. (2012). Indoleamine 2, 3-Dioxygenase and Dendritic cell Tolerogenicity. Immunol Invest, 41, 738-64.
8. Irie-Sasaki J, Sasaki T, Matsumoto W, et al. (2001). CD45 is a JAK phosphatase and negatively regulates cytokine receptor signaling. Nature, 409, 349-54. (Pubitemid 32151240)
9. Johnson TS, Munn DH. (2012). Host Indoleamine 2, 3-Dioxygenase: Contribution to Systemic Acquired Tumor Tolerance. Immunol Invest, 41, 765-97.
10. Kel JM, Girard-Madoux MJ, Reizis B, Clausen BE. (2010). TGF-beta is required to maintain the pool of immature Langerhans cells in the epidermis. J Immunol, 185, 3248-55.
11. Liu N, Duan TD, Zheng N. (2006). Effects of TGF-beta 1, gene modified donor dendritic cells on immune repulsion. Sichuan Da Xue Xue Bao Yi Xue Ban, 37, 721-5. (Pubitemid 44544988)
12. high dendritic cells in vitro. J Ethnopharmacol, 136, 457-64.
13. + regulatory T cells. Nat Immunol, 9, 632-40. (Pubitemid 351712634)
14. Lob S, Konigsrainer A, Rammensee HG, et al. (2009). Inhibitors of indoleamine 2, 3-dioxygenase for cancer therapy: can we see the wood for trees. Nat Rev Cancer, 9, 445-52.
15. Mantel PY, Schmidt-Weber CB. (2011). Transforming growth factor-beta: recent advances on its role in immune tolerance. Methods Mol Biol, 677, 303-38.
16. + dendritic cells express indoleamine 2, 3-dioxygenase which influence T regulatory/T effectorcell balance and oral tolerance induction. Gut, 59, 595-604.
17. Mellor AL, Munn DH. (2004). IDO expression by dendritic cells: tolerance and tryptophan catabolism. Nat Rev Immunol, 4, 762-74. (Pubitemid 39336293)
18. Messmer D, Hatsukari I, Hitosugi N, et al. (2006). Morphine reciprocally regulates IL-0 and IL-12 production by monocyte-derived human dendritic cells and enhances T cell activation. Mol Med, 12, 284-90. (Pubitemid 46489821)
19. Nasef A, Chapel A, Mazurier C, et al. (2007). Identification of IL-10 and TGF-beta transcripts involved in the inhibition of T-lymphocyte proliferation during cell contact with human msenchymal stem cells. Gene Expr, 13, 217-26. (Pubitemid 47024153)
20. Park J, Babensee JE. (2012). Differential functional effects of biomaterials on dendritic cell maturation. Acta Biomater, 8, 3606-17.
21. Sallusto F, Cella M, Danieli C, Lanzavecchia A. (1995). Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex II compartment: downregulation by cytokines and bacterial products. J Exp Med, 182, 389-400.
22. Son CH, Bae JH, Shin DY, et al. (2013). Enhanced maturation and function of dendritic cells using hydrogel coated plate and antigen electroporation. Immunol Invest, 42, 341-55.
23. Spender LC, O, Brien DI, Simpson D, et al. (2009). TGF-beta induces apoptosis in human B cells by transcriptional regulation of BIK and BCL-XL. Cell Death Differ, 16, 593-602.
24. Takamatsu M, Hirata A, Ohtaki H, et al. (2013). IDO plays an immunosuppressive role in 2, 4, 6-Trinitrobenzene sulfate-induced colitis in mice. J Immunol, 191, 3057-64.
25. Ureta G, Osorio F, Morales J, et al. (2007). Generation of dendritic cells with regulatory properties. Transpl Proc, 9, 633-7. (Pubitemid 46574813)
26. Von Bubnoff D, Scheler M, Wilms H, et al. (2011). Identification of IDO-positive and IDO-negative human dendritic cells after activation by various proinflammatory stimuli. J Immunol, 186, 6701-9.
27. low dendritic cell differentiation. Food Chem Toxicol, 50, 2560-4.
28. Yang L, Pang Y, Moses HL. (2010). TGF-beta and immune cells: an important regulatory axis in the tumor microenvironment and progression. Trends Immunol, 31, 220-7.
29. Ye Z, Huang H, Hao S, et al. (2007). L-10 has a distinct immunoregulatory effect on naive and active T cell subsets. J Interferon Cytokine Res, 27, 1031-8.
30. + T-cell proliferation, induces T-regulatory-cell development and prolongs corneal allograft survival. Invest Ophthalmol Vis Sci, 52, 2640-8.