Mitochondrial ascorbic acid transport is mediated by a low-affinity form of the sodium-coupled ascorbic acid transporter-2

Free Radical Biology and Medicine

Volumn 70, Issue , 2014, Pages 241-254

  Muñoz Montesino, Carola ^a,c   Roa, Francisco J ^a   Peña, Eduardo ^a   González, Mauricio ^a   Sotomayor, Kirsty ^a   Inostroza, Eveling ^a   Muñoz, Carolina A ^a   González, Iván ^a   Maldonado, Mafalda ^a   Soliz, Carlos ^a   Reyes, Alejandro M ^b   Vera, Juan Carlos ^a   Rivas, Coralia I ^a  

^a UNIVERSITY OF CONCEPCIÓN   (Chile)

^b UNIVERSIDAD AUSTRAL DE CHILE   (Chile)

^c INRA Institut National de la Recherche Agronomique   (France)

Author keywords

Ascorbic acid transport; Free radicals; Intracellular ascorbate transporter; Mitochondria; Mitochondrial ascorbate transporter; SVCT2; Transport asymmetry

Indexed keywords

ASCORBIC ACID; DEHYDROASCORBIC ACID; GLUCOSE TRANSPORTER 1; POTASSIUM; SODIUM ASCORBIC ACID COTRANSPORTER; SODIUM COUPLED ASCORBIC TRANSPORTER 2; UNCLASSIFIED DRUG; FREE RADICAL; SLC23A1 PROTEIN, HUMAN; SMALL INTERFERING RNA;

ARTICLE; BINDING AFFINITY; CELL MEMBRANE; CELL STRAIN HEK293; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IMMUNOLOCALIZATION; IMMUNOREACTIVITY; MICROENVIRONMENT; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN EXPRESSION; GENE EXPRESSION REGULATION; GENETICS; HEK293 CELL LINE; METABOLISM; OXIDATION REDUCTION REACTION; TRANSPORT AT THE CELLULAR LEVEL;

ASCORBIC ACID; BIOLOGICAL TRANSPORT; FREE RADICALS; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; MITOCHONDRIA; OXIDATION-REDUCTION; RNA, SMALL INTERFERING; SODIUM-COUPLED VITAMIN C TRANSPORTERS;

EID: 84898010568     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2014.02.021     Document Type: Article

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