Vitamin C is an essential antioxidant that enhances survival of oxidatively stressed human vascular endothelial cells in the presence of a vast molar excess of glutathione

Journal of Biological Chemistry

Volumn 282, Issue 21, 2007, Pages 15506-15515

  Montecinos, Viviana ^a   Guzmán, Paula ^a   Barra, Valeria ^a   Villagrán, Marcelo ^a   Muñoz Montesino, Carola ^a   Sotomayor, Kirsty ^a   Escobar, Elizabeth ^a   Godoy, Alejandro ^a   Mardones, Lorena ^a   Sotomayor, Paula ^a   Guzmán, Catherine ^a   Vásquez, Osmán ^a   Gallardo, Victoria ^a   Van Zundert, Brigitte ^a   Bono, María Rosa ^b   Oñate, Sergio A ^c   Bustamante, Marcelo ^d   Cárcamo, Juan G ^e   Rivas, Coralia I ^a   Vera, Juan Carlos ^a  

^a UNIVERSITY OF CONCEPCIÓN   (Chile)

^b UNIVERSITY OF CHILE   (Chile)

^c ROSWELL PARK CANCER INSTITUTE   (United States)

^d UNIVERSIDAD CATÓLICA DE LA SANTÍSIMA CONCEPCIÓN   (Chile)

^e UNIVERSIDAD AUSTRAL DE CHILE   (Chile)

Author keywords

[No Author keywords available]

Indexed keywords

DEHYDROASCORBIC ACID REDUCTASES; GLUTATHIONE; VITAMIN C;

CARBOXYLIC ACIDS; ENDOTHELIAL CELLS; HYDROGEN PEROXIDE; METABOLISM; POLYPEPTIDES; RESPIRATORY SYSTEM;

VITAMINS;

ANTIOXIDANT; ASCORBIC ACID; CARRIER PROTEIN; DEHYDROASCORBIC ACID REDUCTASE; GLUTATHIONE; HYDROGEN PEROXIDE; OXIDIZING AGENT; OXIDOREDUCTASE;

ANTIOXIDANT ACTIVITY; ARTICLE; CELL ACTIVATION; CELL LEVEL; CELL PROTECTION; CELL SURVIVAL; CELLULAR STRESS RESPONSE; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; DRUG MECHANISM; DRUG METABOLISM; ENDOTHELIUM CELL; EXTRACELLULAR SPACE; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MONOTHERAPY; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY BURST; VASCULAR ENDOTHELIUM; DOSE RESPONSE; DRUG EFFECT; METABOLISM;

ANTIOXIDANTS; ASCORBIC ACID; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; GLUTATHIONE; HUMANS; HYDROGEN PEROXIDE; OXIDANTS; OXIDATION-REDUCTION; OXIDATIVE STRESS; OXIDOREDUCTASES; RESPIRATORY BURST;

EID: 34447505075     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M608361200     Document Type: Article

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