Proteomics analysis of normal and senescent NG108-15 cells: GRP78 plays a negative role in cisplatin-induced senescence in the NG108-15 cell line

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Li, Wei ^a   Wang, Wei ^b   Li, Yan ^a   Wang, Wenwen ^a   Wang, Tian ^a   Li, Li ^a   Han, Zhiqiang ^a   Wang, Shixuan ^a   Ma, Ding ^a   Wang, Hui ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CDC2 PROTEIN; CISPLATIN; DEOXYGLUCOSE; GLUCOSE REGULATED PROTEIN 78; GLUTATHIONE TRANSFERASE M2; ISOMERASE; PEPTIDYLPROLYL ISOMERASE A; PEROXIREDOXIN 1; PROTEIN P53; REGULATOR PROTEIN; UNCLASSIFIED DRUG; VIMENTIN; ANTINEOPLASTIC AGENT; ATM PROTEIN; CALCIUM; HEAT SHOCK PROTEIN; MOLECULAR CHAPERONE GRP78; TRANSCRIPTOME;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CELL LINE; CELL PROTECTION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; FEMALE; GENE FUNCTION; GENE IDENTIFICATION; GENE SILENCING; GLIOMA; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOUSE; NEUROBLASTOMA; NG108 15 CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEOMICS; RAT; REGULATORY MECHANISM; SENESCENCE; TWO DIMENSIONAL ELECTROPHORESIS; ANIMAL; CELL AGING; CELL PROLIFERATION; DRUG EFFECTS; METABOLISM; PHENOTYPE; SECRETION (PROCESS); SIGNAL TRANSDUCTION; TUMOR CELL LINE; UPREGULATION;

ANIMALS; ANTINEOPLASTIC AGENTS; ATAXIA TELANGIECTASIA MUTATED PROTEINS; CALCIUM; CELL AGING; CELL LINE, TUMOR; CELL PROLIFERATION; CISPLATIN; ENDOPLASMIC RETICULUM; FEMALE; HEAT-SHOCK PROTEINS; MICE; PHENOTYPE; PROTEOMICS; RATS; SIGNAL TRANSDUCTION; TRANSCRIPTOME; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

EID: 84897978768     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0090114     Document Type: Article

References (35)

1. Cardus A, Uryga AK, Walters G, Erusalimsky JD (2013) SIRT6 protects human endothelial cells from DNA damage, telomere dysfunction, and senescence. Cardiovascular Research 97: 571-579.
2. Campisi J (2011) Cellular senescence as a tumor-suppressor mechanism. Trends Cell Biol 11: S27-31.
3. Roninson IB (2003) Tumour Cell Senescence in Cancer Treatment. Cancer Res 63:2705-2715.
4. Fang K, Chiu CC, Li CH, Chang YT, Hwang HT (2007) Cisplatin-Induced Senescence and Growth Inhibition in Human Non-Small Cell Lung Cancer Cells With Ectopic Transfer of p16INK4a. Oncology Research 16: 479-488.
5. te Poele RH, Okorokov AL, Jardine L, Cummings J, Joel SP (2002) DNA damage is able to induce senescence in tumor cells in vitro and in vivo. Cancer Res 62: 1876-1883. (Pubitemid 34408516)
6. Lee AS (2001) The glucose-regulated proteins: stress induction and clinical applications. Trends Biochem Sci 26: 504-510.
7. Baumeister P, Dong D, Fu Y, Lee AS (2009) Transcriptional induction of GRP78/BiP by histone deacetylase inhibitors and resistance to histone deacetylase inhibitor-induced apoptosis. Mol Cancer Ther 8(5): 1086-1094.
8. Wang M, Ye R, Barron E, Baumeister P, Mao C, et al. (2010) Essential role of the unfolded protein response regulator GRP78/BiP in protection from neuronal apoptosis. Cell Death and Differentiation 17: 488-498.
9. Elmore LW, Xu D, Dumur C, Holt SE, Gewirtz DA (2005) Evasion of a Single-Step, Chemotherapy-Induced Senescence in Breast Cancer Cells: Implications for Treatment Response. Clin Cancer Res 11: 2637-2643. (Pubitemid 40569464)
10. Roberson RS, Kussick SJ, Vallieres E, Chen SJ, Wu DY (2005) Escape from Therapy-Induced Accelerated Cellular Senescence in p53-Null Lung Cancer Cells and in Human Lung Cancers. Cancer Res 65: 2795-2803. (Pubitemid 40490082)
11. Goehe RW, Di X, Sharma K, Bristol ML, Hendersonet SC, et al. (2012) The Autophagy-Senescence Connection in Chemotherapy: Must Tumor Cells (Self) Eat Before They Sleep? J Pharmacol Exp Ther 343: 763-778.
12. Bolesta E, Pfannenstiel LW, Demelash A (2012) Inhibition of Mcl-1 Promotes Senescence in Cancer Cells: Implicationsfor Preventing Tumor Growth and Chemotherapy Resistance. Molecular and Cellular Biology: 1879-1892.
13. Görg A, Obermaier C, Boguth G, Harder A, Scheibe B, et al. (2000) The current state of two-dimensional electrophoresis with immobilized pH gradients. Electrophoresis 21: 1037-1053. (Pubitemid 30230771)
14. Gerner C, Frohwein U, Gotzmann J, Bayer E, Gelbmann D, et al. (2000) The Fas-induced apoptosis analyzed by high throughput proteome analysis. J Biol Chem 275: 39018-39026. (Pubitemid 32058914)
15. Hawkins LK, Johnson L, Bauzon M, Nye JA, Castro D, et al. (2001) Gene delivery from the E3 region of replicating human adenovirus: evaluation of the 6.7 K/gp19 K region. Gene Ther 8: 1123-1131. (Pubitemid 32776385)
16. Wang W, Wang SX, Song XF, Si MN, Xu XH, et al. (2007) The relationship between c-FLIP expression and human papillomavirus E2 gene disruption in cervical carcinogenesis. Gynecologic Oncology 105: 571-577. (Pubitemid 46734183)
17. Wang QS, Zhao XY, He SZ, Liu YS, An MG, et al. (2010) Differential Proteomics Analysis of Specific Carbonylated Proteins in the Temporal Cortex of Aged Rats: The Deterioration of Antioxidant System. Neurochem Res 35: 13-21.
18. Lin HJ, Probst-Hensch NM, Ingles SA, Han CY, Lin BK (1995) Glutathione transferase (GSTM1) null genotype, smoking, and prevalence of colorectal adenomas. Cancer Res 55: 1224-1226.
19. Nishio K, Inoue A, Qiao SJ, Kondo H, Mimura A (2001) Senescence and cytoskeleton: overproduction of vimentin induces senescent-like morphology in human fibroblasts. Histochem Cell Biol 116: 321-327. (Pubitemid 32972326)
20. Fernandez PM, Tabbara SO, Jacobs LK, Manning FC, Tsangaris TN, et al. (2000) Overexpression of the glucose-regulated stress gene GRP78 in malignant but not benign human breast lesions. Breast Cancer Res Treat 59: 15-26. (Pubitemid 30153894)
21. Koomagi R, Mattern J, Volm M (1999) Glucose-related protein (GRP78) and its relationship to the drugresistance proteins P170, GST-pi, LRP56 and angiogenesis in non-small cell lung carcinomas. Anticancer Res 19: 4333-4336.
22. Douglas DT, Cicek GT, Lynn PP (2009) Patient-derived tumour-reactive antibodies as diagnostic markers for ovarian cancer. Gynecologic Oncology 115:112-120.
23. Arap MA, Lahdenranta J, Mintz PJ, Hajitou A, Sarkis AS, et al. (2004) Cell surface expression of the stress response chaperone GRP78 enables tumor targeting by circulating ligands. Cancer Cell 6: 275-284. (Pubitemid 39222040)
24. Zu K, Bihani T, Lin A, Park YM, Mori K, et al. (2006) Enhanced selenium effect on growth arrest by BiP/GRP78 knockdown in P53-null human prostate cancer cells. Oncogene 25: 546-554. (Pubitemid 43164465)
25. Petroulakis E, Parsyan A, Dowling RJ, LeBacquer O, Martineau Y, et al. (2009) P53-Dependent Translational Control of Senescence and Transformation via 4E-BPs. Cancer cell 16: 439-446.
26. Gannon HS, Donehower LA, Lyle S, Jones SN (2011) Mdm2-P53 signaling regulates epidermal stem cell senescence and premature aging phenotypes in mouse skin. Developmental Biology 353: 1-9.
27. Asish G, Kanda K, Steele T, Ray R (2008) Knockdown of MBP-1 in Human Foreskin Fibroblasts Induces P53-P21 Dependent Senescence. PLoS ONE 3 (10):3384.
28. Levine AJ (1997) P53, the cellular gatekeeper for growth and division. Cell 88: 323-331.
29. Rohde M, Daugaard M, Jensen MH, Helin K, Nylandsted J, et al. (2005) Members of the heat-shock protein 70 family promote cancer cell growth by distinct mechanisms. Genes Dev 19: 570-582. (Pubitemid 40314989)
30. Yaglom JA, Gabai VL, Sherman MY (2007) High levels of heat shock protein hsp72 in cancer cells suppress default senescence pathways. Cancer Res 67: 2373-2381. (Pubitemid 46424259)
31. Kaul SC, Aida S, Yaguchi T, Kaur K, Wadhwa R (2005) Activation of wild type P53 function by its mortalin-binding, cytoplasmically localizing carboxyl terminus peptides. J Biol Chem 280: 39373-39379. (Pubitemid 41713894)
32. Giorgi C, Ito K, Lin HK, Santangelo C, Mariusz R (2010) PML Regulates Apoptosis at Endoplasmic Reticulum by Modulating Calcium Release. Science 30: 1247-1251.
33. Al-Bahlani S, Fraser M, Wong AY, Sayan BS, Bergeron R, et al. (2011) P73 regulates cisplatin-induced apoptosis in ovarian cancer cells via a calcium/calpain-dependent mechanism. Oncogene 30: 4219-4230.
34. Bosche B, Schäfer M, Graf R, Härtel FV, Schäfer U, et al. (2013) Lithium prevents early cytosolic calcium increase and secondary injurious calcium overload in glycolytically inhibited endothelial cells. Biochemical and Biophysical Research Communications 434: 268-272.
35. Ikenouchi H, Kohmoto O, McMillan M, Barry WH (1991) Contributions of [Ca2+], [P.], and pH to Altered Diastolic Myocyte Tone during Partial Metabolic Inhibition. J Clin Invest 88: 55-61.