Nanoscale structure-activity relationships, mode of action, and biocompatibility of gold nanoparticle antibiotics

Journal of the American Chemical Society

Volumn 136, Issue 14, 2014, Pages 5295-5300

  Bresee, Jamee ^a   Bond, Constance M ^b   Worthington, Roberta J ^b   Smith, Candice A ^a   Gifford, Jennifer C ^a   Simpson, Carrie A ^a   Carter, Carly J ^a   Wang, Guankui ^a   Hartman, Jesse ^a   Osbaugh, Niki A ^a   Shoemaker, Richard K ^a   Melander, Christian ^b   Feldheim, Daniel L ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTICS; BIOCOMPATIBILITY; ESCHERICHIA COLI; GOLD; METAL NANOPARTICLES; MOLECULES;

BACTERIAL INFECTIONS; COMBINATORIAL SCREENINGS; GLOBAL PUBLIC HEALTH; GRAM-NEGATIVE BACTERIA; KLEBSIELLA PNEUMONIAE; NANOPARTICLE CONJUGATE; SMALL-MOLECULE DRUGS; STRUCTURE ACTIVITY RELATIONSHIPS;

BACTERIA;

ANTIBIOTIC AGENT; GOLD NANOPARTICLE; LIGAND; NANOMATERIAL; ANTIINFECTIVE AGENT; BIOMATERIAL; GOLD; METAL NANOPARTICLE;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL INFECTION; BIOCOMPATIBILITY; CELL DIVISION; CELL MEMBRANE; CONJUGATE; CONTROLLED STUDY; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG MECHANISM; DRUG SCREENING; ESCHERICHIA COLI; KLEBSIELLA PNEUMONIAE; MAMMAL CELL; MULTIDRUG RESISTANCE; NONHUMAN; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; MICROBIAL SENSITIVITY TEST; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANTI-BACTERIAL AGENTS; BIOCOMPATIBLE MATERIALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ESCHERICHIA COLI; GOLD; KLEBSIELLA PNEUMONIAE; METAL NANOPARTICLES; MICROBIAL SENSITIVITY TESTS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84897973533     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja408505n     Document Type: Article

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