Gastrointestinal bioavailability of 2.0 nm diameter gold nanoparticles

ACS Nano

Volumn 7, Issue 5, 2013, Pages 3991-3996

  Smith, Candice A ^a   Simpson, Carrie A ^a   Kim, Ganghyeok ^a   Carter, Carly J ^a   Feldheim, Daniel L ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

gastrointestinal absorption; gold nanoparticles; oral bioavailability

Indexed keywords

ABSORPTION EFFICIENCY; GASTROINTESTINAL ABSORPTIONS; GASTROINTESTINAL TRACT; GOLD NANOPARTICLES; ORAL BIOAVAILABILITIES; ORDERS-OF-MAGNITUDE; POLYETHYLENE GLYCOL (PEG); THERAPEUTIC DELIVERY;

BIOCHEMISTRY; DIAGNOSIS; METAL NANOPARTICLES; MOLECULES; POLYETHYLENE GLYCOLS;

GOLD;

4 MERCURIBENZOATE; 4-MERCURIBENZOATE; GLUTATHIONE; GOLD; MACROGOL DERIVATIVE; MERCURIBENZOIC ACID DERIVATIVE; METAL NANOPARTICLE;

ANIMAL; ARTICLE; BAGG ALBINO MOUSE; BIOAVAILABILITY; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; FEMALE; GASTROINTESTINAL TRACT; METABOLISM; MOUSE; PARTICLE SIZE;

ANIMALS; BIOLOGICAL AVAILABILITY; FEMALE; GASTROINTESTINAL TRACT; GLUTATHIONE; GOLD; MERCURIBENZOATES; METAL NANOPARTICLES; MICE; MICE, INBRED BALB C; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PARTICLE SIZE; POLYETHYLENE GLYCOLS;

EID: 84878316146     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn305930e     Document Type: Article

References (27)

1. Cutler, J. I.; Auyeung, E.; Mirkin, C. A. Spherical Nucleic Acids J. Am. Chem. Soc. 2012, 134, 1376-1391
2. Prigodich, A. E.; Randeria, P. S.; Briley, W. E.; Kim, N. J.; Daniel, W. L.; Giljohann, D. A.; Mirkin, C. A. Multiplexed Nanoflares: mRNA Detection in Live Cells Anal. Chem. 2012, 84, 2062-2066
3. Prigodich, A. E.; Seferos, D. S.; Massich, M. D.; Giljohann, D. A.; Lane, B. C.; Mirkin, C. A. Nano-flares for mRNA Regulation and Detection ACS Nano 2009, 3, 2147-2152
4. Bardhan, R.; Chen, W.; Perez-Torres, C.; Bartels, M.; Huschka, R. M.; Zhao, L. L.; Morosan, E.; Pautler, R. G.; Joshi, A.; Halas, N. J. Nanoshells with Targeted Simultaneous Enhancement of Magnetic and Optical Imaging and Photothermal Therapeutic Response Adv. Funct. Mater. 2009, 19, 3901-3909
5. Lal, S.; Clare, S. E.; Halas, N. J. Nanoshell-Enabled Photothermal Cancer Therapy: Impending Clinical Impact Acc. Chem. Res. 2008, 41, 1842-1851
6. Lowery, A. R.; Gobin, A. M.; Day, E. S.; Halas, N. J.; West, J. L. Immunonanoshells for Targeted Photothermal Ablation of Tumor Cells Int. J. Nanomed. 2006, 1, 149-154
7. Dickerson, E. B.; Dreaden, E. C.; Huang, X.; El-Sayed, H.; Chu, H.; Pushpanketh, S.; McDonald, J. F.; El-Sayed, M. A. Gold Nanorod Assisted Near-Infrared Plasmonic Photothermal Therapy (PPTT) of Squamous Cell Carcinoma in Mice Cancer Lett. 2008, 269, 57-66
8. Huang, X. H.; Jain, P. K.; El-Sayed, I. H.; El-Sayed, M. A. Plasmonic Photothermal Therapy (PPTT) Using Gold Nanoparticles Lasers Med. Sci. 2008, 23, 217-228
9. Xia, Y. N.; Li, W.; Cobley, C. M.; Chen, J.; Xia, X.; Zhang, Q.; Yang, M.; Cho, E. C.; Brown, P. K. Gold Nanocages: From Synthesis to Theranostic Applications Acc. Chem. Res. 2011, 44, 914-924
10. Agbasi-Porter, C.; Ryman-Rasmussen, J.; Franzen, S.; Feldheim, D. L. Transcription Inhibition Using Oligonucleotide-Modified Gold Nanoparticles Bioconjugate Chem. 2006, 17, 1178-1183
11. Ryan, J. A.; Overton, K. W.; Speight, M. E.; Oldenburg, C. N.; Loo, L.; Robarge, W.; Franzen, S.; Feldheim, D. L. Cellular Uptake of Gold Nanoparticles Passivated with BSA-SV40 Large T Antigen Conjugates Anal. Chem. 2007, 79, 9150-9159
12. Tkachenko, A. G.; Xie, H.; Coleman, D.; Glomm, W.; Ryan, J.; Anderson, M. F.; Franzen, S.; Feldheim, D. L. Multifunctional Gold Nanoparticle-Peptide Complexes for Nuclear Targeting J. Am. Chem. Soc. 2003, 125, 4700-4701
13. Zheng, D.; Giljohann, D. A.; Chen, D. L.; Massich, M. D.; Wang, X. Q.; Iordanov, H.; Mirkin, C. A.; Paller, A. S. Topical Delivery of siRNA-Based Spherical Nucleic Acid Nanoparticle Conjugates for Gene Regulation Proc. Natl. Acad. Sci. U.S.A. 2012, 109, 11975-11980
14. Bowman, M. C.; Ballard, T. E.; Ackerson, C. J.; Feldheim, D. L.; Margolis, D. M.; Melander, C. Inhibition of HIV Fusion with Multivalent Gold Nanoparticles J. Am. Chem. Soc. 2008, 130, 6896
15. Bresee, J.; Maier, K. E.; Boncella, A. E.; Melander, C.; Feldheim, D. L. Growth Inhibition of Staphylococcus aureus by Mixed Monolayer Gold Nanoparticles Small 2011, 7, 2027-2031
16. Bresee, J.; Maier, K. E.; Melander, C.; Feldheim, D. L. Identification of Antibiotics Using Small Molecule Variable Ligand Display on Gold Nanoparticles Chem. Commun. 2010, 46, 7516-7518
17. Hillyer, J. F.; Albrecht, R. M. Gastrointestinal Persorption and Tissue Distribution of Differently Sized Colloidal Gold Nanoparticles J. Pharm. Sci. 2001, 90, 1927-1936
18. Schleh, C.; Semmler-Behnke, M.; Lipka, J.; Wenk, A.; Hirn, S.; Schaffler, M.; Schmid, G.; Simon, U.; Kreyling, W. G. Size and Surface Charge of Gold Nanoparticles Determine Absorption across Intestinal Barriers and Accumulation in Secondary Target Organs after Oral Administration Nanotoxicology 2012, 6, 36-46
19. Donovan, M. D.; Flynn, G. L.; Amidon, G. L. Absorption of Polyethylene Glycols 600 through 2000: The Molecular Weight Dependence of Gastrointestinal and Nasal Absorption Pharm. Res. 1990, 7, 863-868
20. Simpson, C. A.; Salleng, K. J.; Cliffel, D. E.; Feldheim, D. L. In Vivo Toxicity, Biodistribution, and Clearance of Glutathione-Coated Gold Nanoparticles Nanomedicine 2013, 9, 257-263
21. Witschi, A.; Reddy, S.; Stofer, B.; Lauterburg, B. H. The Systematic Availability of Oral Glutathione Eur. J. Clin. Pharm. 1992, 43, 667-669
22. Simpson, C. A.; Agrawal, A. C.; Balinski, A.; Harkness, K. M.; Cliffel, D. E. Short-Chain PEG Mixed Monolayer Protected Gold Clusters Increase Clearance and Red Blood Cell Counts ACS Nano 2011, 5, 3577-3584
23. Jadzinsky, P. D.; Calero, G.; Ackerson, C. J.; Bushnell, D. A.; Kornberg, R. D. Structure of a Thiol Monolayer-Protected Gold Nanoparticle at 1.1 Angstrom Resolution Science 2007, 318, 430-433
24. Golde, W. T.; Gollobin, P.; Rodriguez, L. L. A Rapid, Simple, and Humane Method for Submandibular Bleeding of Mice Using a Lancet LabAnimal 2005, 34, 39-43
25. NIH guideline for animal care and use: http://oacu.od.nih.gov/ARAC/ Bleeding.pdf (2005).
26. Kurien, B. T.; Scofield, R. H. Mouse Urine Collection Using Clear Plastic Wrap Lab. Anim. 1998, 33, 83-86
27. Guyton, A. C.; Hall, J. E. Textbook of Medical Physiology; Elsevier Saunders: Philadelphia, PA, 2006.