The anti-lung cancer activity of SEP is mediated by the activation and cytotoxicity of NK cells via TLR2/4 in vivo

Biochemical Pharmacology

Volumn 89, Issue 1, 2014, Pages 119-130

  Ke, Mengyun ^a   Wang, Hui ^a   Zhang, Min ^a   Tian, Yuwei ^a   Wang, Yizhou ^a   Li, Bing ^a   Yu, Jie ^a   Dou, Jie ^a   Xi, Tao ^a   Zhou, Changlin ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Immunotherapy; Lung cancer; Natural killer cell; SEP; TLR

Indexed keywords

ANTINEOPLASTIC AGENT; GAMMA INTERFERON; GANGLIOSIDE GM1 ANTIBODY; INTERLEUKIN 2; PACLITAXEL; POLYSACCHARIDE; STRONGYLOCENTROTUS NUDUS EGG POLYSACCHARIDE; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CD3+ T LYMPHOCYTE; CELL POPULATION; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXICITY; DRUG MECHANISM; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LEWIS CARCINOMA; LUNG NON SMALL CELL CANCER; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPLEEN CELL; T CELL DEPLETION; TUMOR CELL; WILD TYPE;

IMMUNOTHERAPY; LUNG CANCER; NATURAL KILLER CELL; SEP; TLR;

ANIMALS; BASE SEQUENCE; CARCINOMA, LEWIS LUNG; CELL LINE, TUMOR; CYTOTOXICITY, IMMUNOLOGIC; DNA PRIMERS; FEMALE; HUMANS; KILLER CELLS, NATURAL; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; POLYSACCHARIDES; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STRONGYLOCENTROTUS; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4;

EID: 84897973125     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2014.02.024     Document Type: Article

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