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Volumn 4, Issue 4, 2014, Pages 390-391

Metabolic dysregulation in melanoma: Cause or consequence?

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; B RAF KINASE; B RAF KINASE INHIBITOR; DEOXYGLUCOSE; DICHLOROACETIC ACID; HEXOKINASE; HYPOXIA INDUCIBLE FACTOR 1 ALPHA INHIBITOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LACTATE DEHYDROGENASE; MITOGEN ACTIVATED PROTEIN KINASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PYRUVATE DEHYDROGENASE KINASE; PYRUVATE DEHYDROGENASE KINASE INHIBITOR; UNCLASSIFIED DRUG; BRAF PROTEIN, HUMAN; PROTEIN KINASE INHIBITOR;

EID: 84897937661     PISSN: 21598274     EISSN: 21598290     Source Type: Journal    
DOI: 10.1158/2159-8290.CD-14-0173     Document Type: Article
Times cited : (10)

References (10)
  • 4
    • 84897933246 scopus 로고    scopus 로고
    • Response of BRAF-mutant melanoma to BRAF inhibition is mediated by a network of transcriptional regulators of glycolysis
    • Parmenter TJ, Kleinschmidt M, Kinross KM, Bond ST, Li J, Kaadige MR, et al. Response of BRAF-mutant melanoma to BRAF inhibition is mediated by a network of transcriptional regulators of glycolysis. Cancer Discov 2014;4:423-33.
    • (2014) Cancer Discov , vol.4 , pp. 423-433
    • Parmenter, T.J.1    Kleinschmidt, M.2    Kinross, K.M.3    Bond, S.T.4    Li, J.5    Kaadige, M.R.6
  • 5
    • 33644614520 scopus 로고    scopus 로고
    • HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
    • Kim J-W, Tchernyshyov I, Semenza GL, Dang CV. HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia. Cell Metab 2006; 3: 177-85.
    • (2006) Cell Metab , vol.3 , pp. 177-185
    • Kim, J.-W.1    Tchernyshyov, I.2    Semenza, G.L.3    Dang, C.V.4
  • 6
    • 33644622570 scopus 로고    scopus 로고
    • HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
    • Papandreou I, Cairns RA, Fontana L, Lim AL, Denko NC. HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption. Cell Metab 2006; 3: 187-97.
    • (2006) Cell Metab , vol.3 , pp. 187-197
    • Papandreou, I.1    Cairns, R.A.2    Fontana, L.3    Lim, A.L.4    Denko, N.C.5
  • 7
    • 34547225129 scopus 로고    scopus 로고
    • Metabolic targeting of hypoxia and HIF1 in solid tumors can enhance cytotoxic chemotherapy
    • Cairns RA, Papandreou I, Sutphin PD, Denko NC. Metabolic targeting of hypoxia and HIF1 in solid tumors can enhance cytotoxic chemotherapy. Proc Natl Acad Sci U S A 2007; 104: 9445-50.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 9445-9450
    • Cairns, R.A.1    Papandreou, I.2    Sutphin, P.D.3    Denko, N.C.4
  • 9
    • 84881557242 scopus 로고    scopus 로고
    • Hexokinase 2 is required for tumor initiation and maintenance and its systemic deletion is therapeutic in mouse models of cancer
    • Patra KC, Wang Q, Bhaskar PT, Miller L, Wang Z, Wheaton W, et al. Hexokinase 2 is required for tumor initiation and maintenance and its systemic deletion is therapeutic in mouse models of cancer. Cancer Cell 2013; 24: 213-28.
    • (2013) Cancer Cell , vol.24 , pp. 213-228
    • Patra, K.C.1    Wang, Q.2    Bhaskar, P.T.3    Miller, L.4    Wang, Z.5    Wheaton, W.6
  • 10
    • 58649110598 scopus 로고    scopus 로고
    • Oncogenic B-RAF negatively regulates the tumor suppressor LKB1 to promote melanoma cell proliferation
    • Zheng B, Jeong JH, Asara JM, Yuan Y-Y, Granter SR, Chin L, et al. Oncogenic B-RAF negatively regulates the tumor suppressor LKB1 to promote melanoma cell proliferation. Mol Cell 2009; 33: 237-47.
    • (2009) Mol Cell , vol.33 , pp. 237-247
    • Zheng, B.1    Jeong, J.H.2    Asara, J.M.3    Yuan, Y.-Y.4    Granter, S.R.5    Chin, L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.