Regeneration of human-ear-shaped cartilage by co-culturing human microtia chondrocytes with BMSCs

Biomaterials

Volumn 35, Issue 18, 2014, Pages 4878-4887

  Zhang, Lu ^a,b   He, Aijuan ^a,b   Yin, Zongqi ^a,b   Yu, Zheyuan ^a   Luo, Xusong ^a   Liu, Wei ^a,b   Zhang, Wenjie ^a,b   Cao, Yilin ^a,b   Liu, Yu ^a,b   Zhou, Guangdong ^a,b  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b National Tissue Engineering Center of China   (China)

Author keywords

Bone marrow stromal cells; Co culture; Human ear shaped cartilage; Microtia chondrocytes; Regeneration

Indexed keywords

BONE; CARTILAGE; CYTOLOGY; STEM CELLS;

BONE MARROW STROMAL CELLS; CHONDROCYTES; CO-CULTURES; HUMAN EAR; REGENERATION;

SCAFFOLDS (BIOLOGY);

TISSUE SCAFFOLD;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIODEGRADABLE IMPLANT; CARTILAGE CELL; CELL LABELING; CELL PROLIFERATION; CELL TRANSFORMATION; CHONDROGENESIS; COCULTURE; CONTROLLED STUDY; DONOR SITE; EAR RECONSTRUCTION; ELASTICITY; FEASIBILITY STUDY; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; HUMAN EAR SHAPED CARTILAGE; HUMAN TISSUE; MICROTIA; MIXED CELL CULTURE; MORBIDITY; MOUSE; NONHUMAN; NUDE MOUSE; OSSIFICATION; PRIORITY JOURNAL; STEM CELL NICHE; TISSUE ENGINEERING; TISSUE IMPLANT; TISSUE REGENERATION; ANIMAL; CYTOLOGY; EAR CARTILAGE; GOAT; IMMUNOHISTOCHEMISTRY; MESENCHYMAL STROMA CELL; METABOLISM; PHYSIOLOGY; PROCEDURES; REGENERATION; TISSUE SCAFFOLD;

MUS MUSCULUS;

ANIMALS; CELL PROLIFERATION; CHONDROCYTES; CHONDROGENESIS; COCULTURE TECHNIQUES; CONGENITAL MICROTIA; EAR CARTILAGE; GOATS; HUMANS; IMMUNOHISTOCHEMISTRY; MESENCHYMAL STROMAL CELLS; REGENERATION; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 84897912134     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2014.02.043     Document Type: Article

References (44)

1. Tollefson T.T. Advances in the treatment of microtia. Curr Opin Otolaryngol Head Neck Surg 2006, 14(6):412-422.
2. Forrester M.B., Merz R.D. Impact of excluding cases with known chromosomal abnormalities on the prevalence of structural birth defects, Hawaii, 1986-1999. Am J Med Genet A 2004, 128A(4):383-388.
3. Steffen A., Klaiber S., Katzbach R., Nitsch S., Konig I.R., Frenzel H. The psychosocial consequences of reconstruction of severe ear defects or third-degree microtia with rib cartilage. Aesthet Surg J 2008, 28(4):404-411.
4. Brent B. Microtia repair with rib cartilage grafts: a review of personal experience with 1000 cases. Clin Plast Surg 2002, 29(2):257-271.
5. Langer R., Vacanti J.P. Tissue engineering. Science 1993, 260(5110):920-926.
6. Vacanti J.P., Langer R. Tissue engineering: the design and fabrication of living replacement devices for surgical reconstruction and transplantation. Lancet 1999, 354(Suppl. 1):I32-I34.
7. Liu Y., Zhang L., Zhou G., Li Q., Liu W., Yu Z., et al. In vitro engineering of human ear-shaped cartilage assisted with CAD/CAM technology. Biomaterials 2010, 31(8):2176-2183.
8. Cao Y., Vacanti J.P., Paige K.T., Upton J., Vacanti C.A. Transplantation of chondrocytes utilizing a polymer-cell construct to produce tissue-engineered cartilage in the shape of a human ear. Plast Reconstr Surg 1997, 100(2):297-304.
9. Zhou L., Pomerantseva I., Bassett E.K., Bowley C.M., Zhao X., Bichara D.A., et al. Engineering ear constructs with a composite scaffold to maintain dimensions. Tissue Eng Part A 2011, 17(11-12):1573-1581.
10. Saim L., Aminuddin B.S., Munirah S., Chua K.H., Izuddin F.A., Fuzina N.H., et al. Formation of tissue-engineered human auricular cartilage via tissue engineering technique for future use in ear surgery. Med J Malaysia 2004, 59(Suppl. B):192-193.
11. Haisch A. Ear reconstruction through tissue engineering. Adv Otorhinolaryngol 2010, 68:108-119.
12. Staudenmaier R., Hoang N.T., Mandlik V., Schurr C., Burghartz M., Hauber K., et al. Customized tissue engineering for ear reconstruction. Adv Otorhinolaryngol 2010, 68:120-131.
13. Kusuhara H., Isogai N., Enjo M., Otani H., Ikada Y., Jacquet R., et al. Tissue engineering a model for the human ear: assessment of size, shape, morphology, and gene expression following seeding of different chondrocytes. Wound Repair Regen 2009, 17(1):136-146.
14. Nayyer L., Patel K.H., Esmaeili A., Rippel R.A., Birchall M., O'Toole G., et al. Tissue engineering: revolution and challenge in auricular cartilage reconstruction. Plast Reconstr Surg 2012, 129(5):1123-1137.
15. Xue J., Feng B., Zheng R., Lu Y., Zhou G., Liu W., et al. Engineering ear-shaped cartilage using electrospun fibrous membranes of gelatin/polycaprolactone. Biomaterials 2013, 34(11):2624-2631.
16. Isogai N., Kusuhara H., Ikada Y., Ohtani H., Jacquet R., Hillyer J., et al. Comparison of different chondrocytes for use in tissue engineering of cartilage model structures. Tissue Eng 2006, 12(4):691-703.
17. Xu J.W., Zaporojan V., Peretti G.M., Roses R.E., Morse K.B., Roy A.K., et al. Injectable tissue-engineered cartilage with different chondrocyte sources. Plast Reconstr Surg 2004, 113(5):1361-1371.
18. Oseni A.O., Butler P.E., Seifalian A.M. Optimization of chondrocyte isolation and characterization for large-scale cartilage tissue engineering. J Surg Res 2013, 181(1):41-48.
19. Takahashi T., Ogasawara T., Kishimoto J., Liu G., Asato H., Nakatsuka T., et al. Synergistic effects of FGF-2 with insulin or IGF-I on the proliferation of human auricular chondrocytes. Cell Transpl 2005, 14(9):683-693.
20. Kamil S.H., Rodrigruez A., Vacanti C.A., Eavey R.D., Vacanti M.P. Expansion of the number of human auricular chondrocytes: recycling of culture media containing floating cells. Tissue Eng 2004, 10(1-2):139-144.
21. Yanaga H., Imai K., Tanaka Y., Yanaga K. Two-stage transplantation of cell-engineered autologous auricular chondrocytes to regenerate chondrofat composite tissue: clinical application in regenerative surgery. Plast Reconstr Surg 2013, 132(6):1467-1477.
22. Yanaga H., Imai K., Fujimoto T., Yanaga K. Generating ears from cultured autologous auricular chondrocytes by using two-stage implantation in treatment of microtia. Plast Reconstr Surg 2009, 124(3):817-825.
23. Pittenger M.F., Mackay A.M., Beck S.C., Jaiswal R.K., Douglas R., Mosca J.D., et al. Multilineage potential of adult human mesenchymal stem cells. Science 1999, 284(5411):143-147.
24. Pelttari K., Winter A., Steck E., Goetzke K., Hennig T., Ochs B.G., et al. Premature induction of hypertrophy during in vitro chondrogenesis of human mesenchymal stem cells correlates with calcification and vascular invasion after ectopic transplantation in SCID mice. Arthritis Rheum 2006, 54(10):3254-3266.
25. Liu K., Zhou G.D., Liu W., Zhang W.J., Cui L., Liu X., et al. The dependence of in vivo stable ectopic chondrogenesis by human mesenchymal stem cells on chondrogenic differentiation in vitro. Biomaterials 2008, 29(14):2183-2192.
26. Tsuchiya K., Chen G., Ushida T., Matsuno T., Tateishi T. The effect of coculture of chondrocytes with mesenchymal stem cells on their cartilaginous phenotype in vitro. Mater Sci Eng C 2004, 24(3):391-396.
27. Fischer J., Dickhut A., Rickert M., Richter W. Human articular chondrocytes secrete parathyroid hormone-related protein and inhibit hypertrophy of mesenchymal stem cells in coculture during chondrogenesis. Arthritis Rheum 2010, 62(9):2696-2706.
28. Bian L., Zhai D.Y., Mauck R.L., Burdick J.A. Coculture of human mesenchymal stem cells and articular chondrocytes reduces hypertrophy and enhances functional properties of engineered cartilage. Tissue Eng Part A 2011, 17(7-8):1137-1145.
29. Wang M., Rahnama R., Cheng T., Grotkopp E., Jacobs L., Limburg S., et al. Trophic stimulation of articular chondrocytes by late-passage mesenchymal stem cells in coculture. J Orthop Res 2013, 31(12):1936-1942.
30. Wu L., Leijten J.C., Georgi N., Post J.N., van Blitterswijk C.A., Karperien M. Trophic effects of mesenchymal stem cells increase chondrocyte proliferation and matrix formation. Tissue Eng Part A 2011, 17(9-10):1425-1436.
31. Liu X., Sun H., Yan D., Zhang L., Lv X., Liu T., et al. In vivo ectopic chondrogenesis of BMSCs directed by mature chondrocytes. Biomaterials 2010, 31(36):9406-9414.
32. Kang N., Liu X., Guan Y., Wang J., Gong F., Yang X., et al. Effects of co-culturing BMSCs and auricular chondrocytes on the elastic modulus and hypertrophy of tissue engineered cartilage. Biomaterials 2012, 33(18):4535-4544.
33. Ishak M.F., Chua K.H., Asma A., Saim L., Aminuddin B.S., Ruszymah B.H., et al. Stem cell genes are poorly expressed in chondrocytes from microtic cartilage. Int J Pediatr Otorhinolaryngol 2011, 75(6):835-840.
34. Jiang T., Liu W., Lv X., Sun H., Zhang L., Liu Y., et al. Potent in vitro chondrogenesis of CD105 enriched human adipose-derived stem cells. Biomaterials 2010, 31(13):3564-3571.
35. Tew S.R., Murdoch A.D., Rauchenberg R.P., Hardingham T.E. Cellular methods in cartilage research: primary human chondrocytes in culture and chondrogenesis in human bone marrow stem cells. Methods 2008, 45(1):2-9.
36. Yan D., Zhou G., Zhou X., Liu W., Zhang W.J., Luo X., et al. The impact of low levels of collagen IX and pyridinoline on the mechanical properties of in vitro engineered cartilage. Biomaterials 2009, 30(5):814-821.
37. Zhou G., Liu W., Cui L., Wang X., Liu T., Cao Y. Repair of porcine articular osteochondral defects in non-weightbearing areas with autologous bone marrow stromal cells. Tissue Eng 2006, 12(11):3209-3221.
38. Spiller K.L., Liu Y., Holloway J.L., Maher S.A., Cao Y., Liu W., et al. A novel method for the direct fabrication of growth factor-loaded microspheres within porous nondegradable hydrogels: controlled release for cartilage tissue engineering. J Control Release 2012, 157(1):39-45.
39. Ho S.T., Yang Z., Hui H.P., Oh K.W., Choo B.H., Lee E.H. A serum free approach towards the conservation of chondrogenic phenotype during in vitro cell expansion. Growth Factors 2009, 27(5):321-333.
40. Richter W. Mesenchymal stem cells and cartilage in situ regeneration. J Intern Med 2009, 266(4):390-405.
41. Dickhut A., Pelttari K., Janicki P., Wagner W., Eckstein V., Egermann M., et al. Calcification or dedifferentiation: requirement to lock mesenchymal stem cells in a desired differentiation stage. J Cell Physiol 2009, 219(1):219-226.
42. Cooke M.E., Allon A.A., Cheng T., Kuo A.C., Kim H.T., Vail T.P., et al. Structured three-dimensional co-culture of mesenchymal stem cells with chondrocytes promotes chondrogenic differentiation without hypertrophy. Osteoarthr Cartil 2011, 19(10):1210-1218.
43. Wu L., Prins H.J., Helder M.N., van Blitterswijk C.A., Karperien M. Trophic effects of mesenchymal stem cells in chondrocyte co-cultures are independent of culture conditions and cell sources. Tissue Eng Part A 2012, 18(15-16):1542-1551.
44. Meretoja V.V., Dahlin R.L., Kasper F.K., Mikos A.G. Enhanced chondrogenesis in co-cultures with articular chondrocytes and mesenchymal stem cells. Biomaterials 2012, 33(27):6362-6369.