Trophic effects of mesenchymal stem cells in chondrocyte Co-Cultures are independent of culture conditions and cell sources

Tissue Engineering - Part A

Volumn 18, Issue 15-16, 2012, Pages 1542-1551

  Wu, Ling ^a   Prins, Henk Jan ^b,c   Helder, Marco N ^c   Van Blitterswijk, Clemens A ^a   Karperien, Marcel ^a  

^a UNIVERSITY OF TWENTE   (Netherlands)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

^c VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BODY FLUIDS; CARTILAGE; FLOWCHARTING; MAMMALS; PELLETIZING; POLYMERASE CHAIN REACTION; STEM CELLS; TISSUE;

ADIPOSE TISSUE; BONE MARROW-DERIVED MESENCHYMAL STEM CELLS; CARTILAGE FORMATION; CARTILAGE REPAIR; CELL SOURCES; CELL TRACKING; CHONDROCYTE PROLIFERATION; CHONDROCYTES; CHONDROGENIC DIFFERENTIATION; CO-CULTURES; COCULTURE; CULTURE CONDITIONS; CULTURE MEDIUM; GENOMIC DNA; GLYCOSAMINOGLYCANS; MESENCHYMAL STEM CELL; PRIMARY CHONDROCYTES; QUANTITATIVE POLYMERASE CHAIN REACTION; SHORT TANDEM REPEATS;

CELL CULTURE;

GLYCOSAMINOGLYCAN;

ANIMAL; ARTICLE; BIOSYNTHESIS; CARTILAGE CELL; CATTLE; CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; CHONDROGENESIS; COCULTURE; CULTURE MEDIUM; CULTURE TECHNIQUE; CYTOLOGY; DRUG EFFECT; EXTRACELLULAR MATRIX; HUMAN; MESENCHYMAL STROMA CELL; METABOLISM; METHODOLOGY;

ANIMALS; CATTLE; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; CHONDROCYTES; CHONDROGENESIS; COCULTURE TECHNIQUES; CULTURE MEDIA; EXTRACELLULAR MATRIX; GLYCOSAMINOGLYCANS; HUMANS; MESENCHYMAL STROMAL CELLS;

EID: 84865253085     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2011.0715     Document Type: Article

References (44)

1. Brittberg, M., Lindahl, A., Nilsson, A., Ohlsson, C., Isaksson, O., and Peterson, L. Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation. N Engl J Med 331, 889, 1994.
2. Hendriks, J., Riesle, J., and van Blitterswijk, C.A. Co-culture in cartilage tissue engineering. J Tissue Eng Regen Med 1, 170, 2007.
3. Tsuchiya, K., Chen, G., Ushida, T., Matsuno, T., and Tateishi, T. The effect of coculture of chondrocytes with mesenchymal stem cells on their cartilaginous phenotype in vitro. Materials Science & Engineering C-Biomimetic and Supramolecular Systems 24, 6, 2004.
4. Gruber, H.E., Deepe, R., Hoelscher, G.L., Ingram, J.A., Norton, H.J., Scannell, B., et al. Human adipose-derived mesenchymal stem cells: direction to a phenotype sharing similarities with the disc, gene expression profiling, and coculture with human annulus cells. Tissue Eng Part A 16, 2843, 2010.
5. Wu, L., Leijten, J.C., Georgi, N., Post, J.N., van Blitterswijk, C.A., and Karperien, M. Trophic effects of mesenchymal stem cells increase chondrocyte proliferation and matrix formation. Tissue Eng Part A 17, 1425, 2011.
6. Acharya, C., Adesida, A., Zajac, P., Mumme, M., Riesle, J., Martin, I., et al. Enhanced chondrocyte proliferation and mesenchymal stromal cells chondrogenesis in coculture pellets mediate improved cartilage formation. J Cell Physiol 227, 88, 2012.
7. Caplan, A.I., and Dennis, J.E. Mesenchymal stem cells as trophic mediators. J Cell Biochem 98, 1076, 2006.
8. Singer, M. Trophic functions of the neuron. VI. Other trophic systems. Neurotrophic control of limb regeneration in the newt. Ann N Y Acad Sci 228, 308, 1974.
9. Bruder, S.P., Fink, D.J., and Caplan, A.I. Mesenchymal stem cells in bone development, bone repair, and skeletal regeneration therapy. J Cell Biochem 56, 283, 1994.
10. Kassis, I., Vaknin-Dembinsky, A., and Karussis, D. Bone marrow mesenchymal stem cells: agents of immunomodulation and neuroprotection. Curr Stem Cell Res Ther 6, 63, 2011.
11. Li, Y., Chen, J., Zhang, C.L., Wang, L., Lu, D., Katakowski, M., et al. Gliosis and brain remodeling after treatment of stroke in rats with marrow stromal cells. Glia 49, 407, 2005.
12. Sassoli, C., Pini, A., Mazzanti, B., Quercioli, F., Nistri, S., Saccardi, R., et al. Mesenchymal stromal cells affect cardiomyocyte growth through juxtacrine Notch-1/Jagged1 signaling and paracrine mechanisms: clues for cardiac regeneration. J Mol Cell Cardiol 51, 399, 2011.
13. Tang, Y.L., Zhao, Q., Qin, X., Shen, L., Cheng, L., Ge, J., et al. Paracrine action enhances the effects of autologous mesenchymal stem cell transplantation on vascular regeneration in rat model of myocardial infarction. Ann Thorac Surg 80, 229, discussion 36, 2005.
14. Lin, Y., Liu, L., Li, Z., Qiao, J., Wu, L., Tang, W., et al. Pluripotency potential of human adipose-derived stem cells marked with exogenous green fluorescent protein. Mol Cell Biochem 291, 1, 2006.
15. Zuk, P.A., Zhu, M., Mizuno, H., Huang, J., Futrell, J.W., Katz, A.J., et al. Multilineage cells from human adipose tissue: implications for cell-based therapies. Tissue Eng 7, 211, 2001.
16. De Bari, C., Dell'Accio, F., Tylzanowski, P., and Luyten, F.P. Multipotent mesenchymal stem cells from adult human synovial membrane. Arthritis Rheum 44, 1928, 2001.
17. Vemuri, M.C., Chase, L.G., and Rao, M.S. Mesenchymal stem cell assays and applications. Methods Mol Biol 698, 3, 2011.
18. Chen, F.H., and Tuan, R.S. Mesenchymal stem cells in arthritic diseases. Arthritis Res Ther 10, 223, 2008.
19. Motaln, H., Schichor, C., and Lah, T.T. Human mesenchymal stem cells and their use in cell-based therapies. Cancer 116, 2519, 2010.
20. Balber, A.E. Concise review: aldehyde dehydrogenase bright stem and progenitor cell populations from normal tissues: characteristics, activities, and emerging uses in regenerative medicine. Stem Cells 29, 570, 2011.
21. Lin, Y., Tang, W., Wu, L., Jing, W., Li, X., Wu, Y., et al. Bone regeneration by BMP-2 enhanced adipose stem cells loading on alginate gel. Histochem Cell Biol 129, 203, 2008.
22. Wu, L., Zhu, F., Wu, Y., Lin, Y., Nie, X., Jing, W., et al. Dentin sialophosphoprotein-promoted mineralization and expression of odontogenic genes in adipose-derived stromal cells. Cells Tissues Organs 187, 103, 2008.
23. Wu, L., Wu, Y., Lin, Y., Jing, W., Nie, X., Qiao, J., et al. Osteogenic differentiation of adipose derived stem cells promoted by overexpression of osterix. Mol Cell Biochem 301, 83, 2007.
24. Lee, J.I., Sato, M., Kim, H.W., and Mochida, J. Transplantatation of scaffold-free spheroids composed of synoviumderived cells and chondrocytes for the treatment of cartilage defects of the knee. Eur Cell Mater 22, 275, 2011.
25. Xue, G., He, M., Zhao, J., Chen, Y., Tian, Y., Zhao, B., et al. Intravenous umbilical cord mesenchymal stem cell infusion for the treatment of combined malnutrition nonunion of the humerus and radial nerve injury. Regen Med 6, 733, 2011.
26. Park, J., Euhus, D.M., and Scherer, P.E. Paracrine and Endocrine Effects of Adipose Tissue on Cancer Development and Progression. Endocr Rev 32, 550, 2011.
27. Bhang, S.H., Cho, S.W., La, W.G., Lee, T.J., Yang, H.S., Sun, A.Y., et al. Angiogenesis in ischemic tissue produced by spheroid grafting of human adipose-derived stromal cells. Biomaterials 32, 2734, 2011.
28. Hendriks, J., Riesle, J., and Vanblitterswijk, C.A. Effect of stratified culture compared to confluent culture in monolayer on proliferation and differentiation of human articular chondrocytes. Tissue Eng 12, 2397, 2006.
29. Wu, L., Cai, X., Dong, H., Jing, W., Huang, Y., Yang, X., et al. Serum regulates adipogenesis of mesenchymal stem cells via MEK/ERK-dependent PPARgamma expression and phosphorylation. J Cell Mol Med 14, 922, 2010.
30. Jurgens, W.J., Oedayrajsingh-Varma, M.J., Helder, M.N., Zandiehdoulabi, B., Schouten, T.E., Kuik, D.J., et al. Effect of tissue-harvesting site on yield of stem cells derived from adipose tissue: implications for cell-based therapies. Cell Tissue Res 332, 415, 2008.
31. Lee, S.Y., Nakagawa, T., and Reddi, A.H. Mesenchymal progenitor cells derived from synovium and infrapatellar fat pad as a source for superficial zone cartilage tissue engineering: analysis of superficial zone protein/lubricin expression. Tissue Eng Part A 16, 317, 2010.
32. Livak, K.J., and Schmittgen, T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25, 402, 2001.
33. Hwang, N.S., Varghese, S., Puleo, C., Zhang, Z., and Elisseeff, J. Morphogenetic signals from chondrocytes promote chondrogenic and osteogenic differentiation of mesenchymal stem cells. J Cell Physiol 212, 281, 2007.
34. Vadala, G., Studer, R.K., Sowa, G., Spiezia, F., Iucu, C., Denaro, V., et al. Coculture of bone marrow mesenchymal stem cells and nucleus pulposus cells modulate gene expression profile without cell fusion. Spine (Phila Pa 1976) 33, 870, 2008.
35. Lee, J.S., and Im, G.I. Influence of Chondrocytes on the Chondrogenic Differentiation of Adipose Stem Cells. Tissue Eng Part A 16, 3569, 2010.
36. Bigdeli, N., Karlsson, C., Strehl, R., Concaro, S., Hyllner, J., and Lindahl, A. Coculture of human embryonic stem cells and human articular chondrocytes results in significantly altered phenotype and improved chondrogenic differentiation. Stem Cells 27, 1812, 2009.
37. Gunja, N.J., and Athanasiou, K.A. Effects of co-cultures of meniscus cells and articular chondrocytes on PLLA scaffolds. Biotechnol Bioeng 103, 808, 2009.
38. Hildner, F., Concaro, S., Peterbauer, A., Wolbank, S., Danzer, M., Lindahl, A., et al. Human adipose-derived stem cells contribute to chondrogenesis in coculture with human articular chondrocytes. Tissue Eng Part A 15, 3961, 2009.
39. Hendriks, J.A.A., Miclea, R.L., Schotel, R., de Bruijn, E., Moroni, L., Karperien, M., et al. Primary chondrocytes enhance cartilage tissue formation upon co-culture with a range of cell types. Soft Matter 6, 5080, 2010.
40. Witkowska-Zimny, M., and Walenko, K. Stem cells from adipose tissue. Cell Mol Biol Lett 16, 236, 2011.
41. Hildner, F., Albrecht, C., Gabriel, C., Redl, H., and van Griensven, M. State of the art and future perspectives of articular cartilage regeneration: a focus on adipose-derived stem cells and platelet-derived products. J Tissue Eng Regen Med 5, e36, 2011.
42. Wilson, A., Butler, P.E., and Seifalian, A.M. Adipose-derived stem cells for clinical applications: a review. Cell Prolif 44, 86, 2011.
43. Cherubino, M., Rubin, J.P., Miljkovic, N., Kelmendi-Doko, A., and Marra, K.G. Adipose-derived stem cells for woundhealing applications. Ann Plast Surg 66, 210, 2011.
44. Mochizuki, T., Muneta, T., Sakaguchi, Y., Nimura, A., Yokoyama, A., Koga, H., et al. Higher chondrogenic potential of fibrous synovium-and adipose synovium-derived cells compared with subcutaneous fat-derived cells: distinguishing properties of mesenchymal stem cells in humans. ArthritisRheum 54, 843, 2006.